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Mutation is the ultimate source of all genetic variation and is, therefore, central to evolutionary change. Previous work on Paramecium tetraurelia found an unusually low germline base-substitution mutation rate in

Mutation is the ultimate source of all genetic variation and is, therefore, central to evolutionary change. Previous work on Paramecium tetraurelia found an unusually low germline base-substitution mutation rate in this ciliate. Here, we tested the generality of this result among ciliates using Tetrahymena thermophila. We sequenced the genomes of 10 lines of T. thermophila that had each undergone approximately 1,000 generations of mutation accumulation (MA).

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    Date Created
    • 2016-09-15
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  • Text
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    Identifier
    • Digital object identifier: 10.1093/gbe/evw223
    • Identifier Type
      International standard serial number
      Identifier Value
      1759-6653
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    Long, H., Winter, D. J., Chang, A. Y., Sung, W., Wu, S. H., Balboa, M., . . . Zufall, R. A. (2016). Low Base-Substitution Mutation Rate in the Germline Genome of the CiliateTetrahymena thermophil. Genome Biology and Evolution. doi:10.1093/gbe/evw223

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