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Ultraviolet light in the UVC range is a commonly used disinfectant to control viruses in clinical settings and water treatment. However, it is currently unknown whether human viral pathogens may

Ultraviolet light in the UVC range is a commonly used disinfectant to control viruses in clinical settings and water treatment. However, it is currently unknown whether human viral pathogens may develop resistance to such stressor. Here, we investigate the adaptation of an enteric pathogen, human echovirus 11, to disinfection by UVC, and characterized the underlying phenotypic and genotypic changes. Repeated exposure to UVC lead to a reduction in the UVC inactivation rate of approximately 15 per cent compared to that of the wild-type and the control populations.

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    Date Created
    • 2017-11-20
    Resource Type
  • Text
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    Identifier
    • Digital object identifier: 10.1093/ve/vex035
    • Identifier Type
      International standard serial number
      Identifier Value
      2057-1577
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    Carratalà, A., Shim, H., Zhong, Q., Bachmann, V., Jensen, J. D., & Kohn, T. (2017). Experimental adaptation of human echovirus 11 to ultraviolet radiation leads to resistance to disinfection and ribavirin. Virus Evolution, 3(2). doi:10.1093/ve/vex035

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