This collection includes most of the ASU Theses and Dissertations from 2011 to present. ASU Theses and Dissertations are available in downloadable PDF format; however, a small percentage of items are under embargo. Information about the dissertations/theses includes degree information, committee members, an abstract, supporting data or media.

In addition to the electronic theses found in the ASU Digital Repository, ASU Theses and Dissertations can be found in the ASU Library Catalog.

Dissertations and Theses granted by Arizona State University are archived and made available through a joint effort of the ASU Graduate College and the ASU Libraries. For more information or questions about this collection contact or visit the Digital Repository ETD Library Guide or contact the ASU Graduate College at gradformat@asu.edu.

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Description
The continuous time-tagging of photon arrival times for high count rate sources isnecessary for applications such as optical communications, quantum key encryption, and astronomical measurements. Detection of Hanbury-Brown and Twiss (HBT) single photon correlations from thermal sources, such as stars, requires a combination of high dynamic range, long integration times, and low systematics

The continuous time-tagging of photon arrival times for high count rate sources isnecessary for applications such as optical communications, quantum key encryption, and astronomical measurements. Detection of Hanbury-Brown and Twiss (HBT) single photon correlations from thermal sources, such as stars, requires a combination of high dynamic range, long integration times, and low systematics in the photon detection and time tagging system. The continuous nature of the measurements and the need for highly accurate timing resolution requires a customized time-to-digital converter (TDC). A custom built, two-channel, field programmable gate array (FPGA)-based TDC capable of continuously time tagging single photons with sub clock cycle timing resolution was characterized. Auto-correlation and cross-correlation measurements were used to constrain spurious systematic effects in the pulse count data as a function of system variables. These variables included, but were not limited to, incident photon count rate, incoming signal attenuation, and measurements of fixed signals. Additionally, a generalized likelihood ratio test using maximum likelihood estimators (MLEs) was derived as a means to detect and estimate correlated photon signal parameters. The derived GLRT was capable of detecting correlated photon signals in a laboratory setting with a high degree of statistical confidence. A proof is presented in which the MLE for the amplitude of the correlated photon signal is shown to be the minimum variance unbiased estimator (MVUE). The fully characterized TDC was used in preliminary measurements of astronomical sources using ground based telescopes. Finally, preliminary theoretical groundwork is established for the deep space optical communications system of the proposed Breakthrough Starshot project, in which low-mass craft will travel to the Alpha Centauri system to collect scientific data from Proxima B. This theoretical groundwork utilizes recent and upcoming space based optical communication systems as starting points for the Starshot communication system.
ContributorsHodges, Todd Michael William (Author) / Mauskopf, Philip (Thesis advisor) / Trichopoulos, George (Thesis advisor) / Papandreou-Suppappola, Antonia (Committee member) / Bliss, Daniel (Committee member) / Arizona State University (Publisher)
Created2022
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Description
Statistical process control (SPC) and predictive analytics have been used in industrial manufacturing and design, but up until now have not been applied to threshold data of vital sign monitoring in remote care settings. In this study of 20 elders with COPD and/or CHF, extended months of peak flow monitoring

Statistical process control (SPC) and predictive analytics have been used in industrial manufacturing and design, but up until now have not been applied to threshold data of vital sign monitoring in remote care settings. In this study of 20 elders with COPD and/or CHF, extended months of peak flow monitoring (FEV1) using telemedicine are examined to determine when an earlier or later clinical intervention may have been advised. This study demonstrated that SPC may bring less than a 2.0% increase in clinician workload while providing more robust statistically-derived thresholds than clinician-derived thresholds. Using a random K-fold model, FEV1 output was predictably validated to .80 Generalized R-square, demonstrating the adequate learning of a threshold classifier. Disease severity also impacted the model. Forecasting future FEV1 data points is possible with a complex ARIMA (45, 0, 49), but variation and sources of error require tight control. Validation was above average and encouraging for clinician acceptance. These statistical algorithms provide for the patient's own data to drive reduction in variability and, potentially increase clinician efficiency, improve patient outcome, and cost burden to the health care ecosystem.
ContributorsFralick, Celeste (Author) / Muthuswamy, Jitendran (Thesis advisor) / O'Shea, Terrance (Thesis advisor) / LaBelle, Jeffrey (Committee member) / Pizziconi, Vincent (Committee member) / Shea, Kimberly (Committee member) / Arizona State University (Publisher)
Created2013
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Description
In this work, the author analyzes quantitative and structural aspects of Bayesian inference using Markov kernels, Wasserstein metrics, and Kantorovich monads. In particular, the author shows the following main results: first, that Markov kernels can be viewed as Borel measurable maps with values in a Wasserstein space; second, that the

In this work, the author analyzes quantitative and structural aspects of Bayesian inference using Markov kernels, Wasserstein metrics, and Kantorovich monads. In particular, the author shows the following main results: first, that Markov kernels can be viewed as Borel measurable maps with values in a Wasserstein space; second, that the Disintegration Theorem can be interpreted as a literal equality of integrals using an original theory of integration for Markov kernels; third, that the Kantorovich monad can be defined for Wasserstein metrics of any order; and finally, that, under certain assumptions, a generalized Bayes’s Law for Markov kernels provably leads to convergence of the expected posterior distribution in the Wasserstein metric. These contributions provide a basis for studying further convergence, approximation, and stability properties of Bayesian inverse maps and inference processes using a unified theoretical framework that bridges between statistical inference, machine learning, and probabilistic programming semantics.
ContributorsEikenberry, Keenan (Author) / Cochran, Douglas (Thesis advisor) / Lan, Shiwei (Thesis advisor) / Dasarathy, Gautam (Committee member) / Kotschwar, Brett (Committee member) / Shahbaba, Babak (Committee member) / Arizona State University (Publisher)
Created2023
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Description
This dissertation centers on treatment effect estimation in the field of causal inference, and aims to expand the toolkit for effect estimation when the treatment variable is binary. Two new stochastic tree-ensemble methods for treatment effect estimation in the continuous outcome setting are presented. The Accelerated Bayesian Causal Forrest (XBCF)

This dissertation centers on treatment effect estimation in the field of causal inference, and aims to expand the toolkit for effect estimation when the treatment variable is binary. Two new stochastic tree-ensemble methods for treatment effect estimation in the continuous outcome setting are presented. The Accelerated Bayesian Causal Forrest (XBCF) model handles variance via a group-specific parameter, and the Heteroskedastic version of XBCF (H-XBCF) uses a separate tree ensemble to learn covariate-dependent variance. This work also contributes to the field of survival analysis by proposing a new framework for estimating survival probabilities via density regression. Within this framework, the Heteroskedastic Accelerated Bayesian Additive Regression Trees (H-XBART) model, which is also developed as part of this work, is utilized in treatment effect estimation for right-censored survival outcomes. All models have been implemented as part of the XBART R package, and their performance is evaluated via extensive simulation studies with appropriate sets of comparators. The contributed methods achieve similar levels of performance, while being orders of magnitude (sometimes as much as 100x) faster than comparator state-of-the-art methods, thus offering an exciting opportunity for treatment effect estimation in the large data setting.
ContributorsKrantsevich, Nikolay (Author) / Hahn, P Richard (Thesis advisor) / McCulloch, Robert (Committee member) / Zhou, Shuang (Committee member) / Lan, Shiwei (Committee member) / He, Jingyu (Committee member) / Arizona State University (Publisher)
Created2023
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Description
As the impacts of climate change worsen in the coming decades, natural hazards are expected to increase in frequency and intensity, leading to increased loss and risk to human livelihood. The spatio-temporal statistical approaches developed and applied in this dissertation highlight the ways in which hazard data can be leveraged

As the impacts of climate change worsen in the coming decades, natural hazards are expected to increase in frequency and intensity, leading to increased loss and risk to human livelihood. The spatio-temporal statistical approaches developed and applied in this dissertation highlight the ways in which hazard data can be leveraged to understand loss trends, build forecasts, and study societal impacts of losses. Specifically, this work makes use of the Spatial Hazard Events and Losses Database which is an unparalleled source of loss data for the United States. The first portion of this dissertation develops accurate loss baselines that are crucial for mitigation planning, infrastructure investment, and risk communication. This is accomplished thorough a stationarity analysis of county level losses following a normalization procedure. A wide variety of studies employ loss data without addressing stationarity assumptions or the possibility for spurious regression. This work enables the statistically rigorous application of such loss time series to modeling applications. The second portion of this work develops a novel matrix variate dynamic factor model for spatio-temporal loss data stratified across multiple correlated hazards or perils. The developed model is employed to analyze and forecast losses from convective storms, which constitute some of the highest losses covered by insurers. Adopting factor-based approach, forecasts are achieved despite the complex and often unobserved underlying drivers of these losses. The developed methodology extends the literature on dynamic factor models to matrix variate time series. Specifically, a covariance structure is imposed that is well suited to spatio-temporal problems while significantly reducing model complexity. The model is fit via the EM algorithm and Kalman filter. The third and final part of this dissertation investigates the impact of compounding hazard events on state and regional migration in the United States. Any attempt to capture trends in climate related migration must account for the inherent uncertainties surrounding climate change, natural hazard occurrences, and socioeconomic factors. For this reason, I adopt a Bayesian modeling approach that enables the explicit estimation of the inherent uncertainty. This work can provide decision-makers with greater clarity regarding the extent of knowledge on climate trends.
ContributorsBoyle, Esther Sarai (Author) / Jevtic, Petar (Thesis advisor) / Lanchier, Nicolas (Thesis advisor) / Lan, Shiwei (Committee member) / Cheng, Dan (Committee member) / Fricks, John (Committee member) / Gall, Melanie (Committee member) / Cutter, Susan (Committee member) / McNicholas, Paul (Committee member) / Arizona State University (Publisher)
Created2023
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Description
This dissertation centers on the development of Bayesian methods for learning differ- ent types of variation in switching nonlinear gene regulatory networks (GRNs). A new nonlinear and dynamic multivariate GRN model is introduced to account for different sources of variability in GRNs. The new model is aimed at more precisely

This dissertation centers on the development of Bayesian methods for learning differ- ent types of variation in switching nonlinear gene regulatory networks (GRNs). A new nonlinear and dynamic multivariate GRN model is introduced to account for different sources of variability in GRNs. The new model is aimed at more precisely capturing the complexity of GRN interactions through the introduction of time-varying kinetic order parameters, while allowing for variability in multiple model parameters. This model is used as the drift function in the development of several stochastic GRN mod- els based on Langevin dynamics. Six models are introduced which capture intrinsic and extrinsic noise in GRNs, thereby providing a full characterization of a stochastic regulatory system. A Bayesian hierarchical approach is developed for learning the Langevin model which best describes the noise dynamics at each time step. The trajectory of the state, which are the gene expression values, as well as the indicator corresponding to the correct noise model are estimated via sequential Monte Carlo (SMC) with a high degree of accuracy. To address the problem of time-varying regulatory interactions, a Bayesian hierarchical model is introduced for learning variation in switching GRN architectures with unknown measurement noise covariance. The trajectory of the state and the indicator corresponding to the network configuration at each time point are estimated using SMC. This work is extended to a fully Bayesian hierarchical model to account for uncertainty in the process noise covariance associated with each network architecture. An SMC algorithm with local Gibbs sampling is developed to estimate the trajectory of the state and the indicator correspond- ing to the network configuration at each time point with a high degree of accuracy. The results demonstrate the efficacy of Bayesian methods for learning information in switching nonlinear GRNs.
ContributorsVélez-Cruz, Nayely (Author) / Papandreou-Suppappola, Antonia (Thesis advisor) / Moraffah, Bahman (Committee member) / Tepedelenlioğlu, Cihan (Committee member) / Berisha, Visar (Committee member) / Arizona State University (Publisher)
Created2023
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Description
Uncertainty Quantification (UQ) is crucial in assessing the reliability of predictivemodels that make decisions for human experts in a data-rich world. The Bayesian approach to UQ for inverse problems has gained popularity. However, addressing UQ in high-dimensional inverse problems is challenging due to the intensity and inefficiency of Markov Chain

Uncertainty Quantification (UQ) is crucial in assessing the reliability of predictivemodels that make decisions for human experts in a data-rich world. The Bayesian approach to UQ for inverse problems has gained popularity. However, addressing UQ in high-dimensional inverse problems is challenging due to the intensity and inefficiency of Markov Chain Monte Carlo (MCMC) based Bayesian inference methods. Consequently, the first primary focus of this thesis is enhancing efficiency and scalability for UQ in inverse problems. On the other hand, the omnipresence of spatiotemporal data, particularly in areas like traffic analysis, underscores the need for effectively addressing inverse problems with spatiotemporal observations. Conventional solutions often overlook spatial or temporal correlations, resulting in underutilization of spatiotemporal interactions for parameter learning. Appropriately modeling spatiotemporal observations in inverse problems thus forms another pivotal research avenue. In terms of UQ methodologies, the calibration-emulation-sampling (CES) scheme has emerged as effective for large-dimensional problems. I introduce a novel CES approach by employing deep neural network (DNN) models during the emulation and sampling phase. This approach not only enhances computational efficiency but also diminishes sensitivity to training set variations. The newly devised “Dimension- Reduced Emulative Autoencoder Monte Carlo (DREAM)” algorithm scales Bayesian UQ up to thousands of dimensions in physics-constrained inverse problems. The algorithm’s effectiveness is exemplified through elliptic and advection-diffusion inverse problems. In the realm of spatiotemporal modeling, I propose to use Spatiotemporal Gaussian processes (STGP) in likelihood modeling and Spatiotemporal Besov processes (STBP) in prior modeling separately. These approaches highlight the efficacy of incorporat- ing spatial and temporal information for enhanced parameter estimation and UQ. Additionally, the superiority of STGP is demonstrated compared to static and time- averaged methods in time-dependent advection-diffusion partial differential equation (PDE) and three chaotic ordinary differential equations (ODE). Expanding upon Besov Process (BP), a method known for sparsity-promotion and edge-preservation, STBP is introduced to capture spatial data features and model temporal correlations by replacing the random coefficients in the series expansion with stochastic time functions following Q-exponential process(Q-EP). This advantage is showcased in dynamic computerized tomography (CT) reconstructions through comparison with classic STGP and a time-uncorrelated approach.
ContributorsLi, Shuyi (Author) / Lan, Shiwei (Thesis advisor) / Hahn, Paul (Committee member) / McCulloch, Robert (Committee member) / Dan, Cheng (Committee member) / Lopes, Hedibert (Committee member) / Arizona State University (Publisher)
Created2023