ASU Electronic Theses and Dissertations
This collection includes most of the ASU Theses and Dissertations from 2011 to present. ASU Theses and Dissertations are available in downloadable PDF format; however, a small percentage of items are under embargo. Information about the dissertations/theses includes degree information, committee members, an abstract, supporting data or media.
In addition to the electronic theses found in the ASU Digital Repository, ASU Theses and Dissertations can be found in the ASU Library Catalog.
Dissertations and Theses granted by Arizona State University are archived and made available through a joint effort of the ASU Graduate College and the ASU Libraries. For more information or questions about this collection contact or visit the Digital Repository ETD Library Guide or contact the ASU Graduate College at gradformat@asu.edu.
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- All Subjects: Statistics
- Creators: Moraffah, Bahman
Description
Infants born before 37 weeks of pregnancy are considered to be preterm. Typically, preterm infants have to be strictly monitored since they are highly susceptible to health problems like hypoxemia (low blood oxygen level), apnea, respiratory issues, cardiac problems, neurological problems as well as an increased chance of long-term health issues such as cerebral palsy, asthma and sudden infant death syndrome. One of the leading health complications in preterm infants is bradycardia - which is defined as the slower than expected heart rate, generally beating lower than 60 beats per minute. Bradycardia is often accompanied by low oxygen levels and can cause additional long term health problems in the premature infant.The implementation of a non-parametric method to predict the onset of brady- cardia is presented. This method assumes no prior knowledge of the data and uses kernel density estimation to predict the future onset of bradycardia events. The data is preprocessed, and then analyzed to detect the peaks in the ECG signals, following which different kernels are implemented to estimate the shared underlying distribu- tion of the data. The performance of the algorithm is evaluated using various metrics and the computational challenges and methods to overcome them are also discussed.
It is observed that the performance of the algorithm with regards to the kernels used are consistent with the theoretical performance of the kernel as presented in a previous work. The theoretical approach has also been automated in this work and the various implementation challenges have been addressed.
It is observed that the performance of the algorithm with regards to the kernels used are consistent with the theoretical performance of the kernel as presented in a previous work. The theoretical approach has also been automated in this work and the various implementation challenges have been addressed.
ContributorsMitra, Sinjini (Author) / Papandreou-Suppappola, Antonia (Thesis advisor) / Moraffah, Bahman (Thesis advisor) / Turaga, Pavan (Committee member) / Arizona State University (Publisher)
Created2020
Description
The problem of multiple object tracking seeks to jointly estimate the time-varying cardinality and trajectory of each object. There are numerous challenges that are encountered in tracking multiple objects including a time-varying number of measurements, under varying constraints, and environmental conditions. In this thesis, the proposed statistical methods integrate the use of physical-based models with Bayesian nonparametric methods to address the main challenges in a tracking problem. In particular, Bayesian nonparametric methods are exploited to efficiently and robustly infer object identity and learn time-dependent cardinality; together with Bayesian inference methods, they are also used to associate measurements to objects and estimate the trajectory of objects. These methods differ from the current methods to the core as the existing methods are mainly based on random finite set theory.
The first contribution proposes dependent nonparametric models such as the dependent Dirichlet process and the dependent Pitman-Yor process to capture the inherent time-dependency in the problem at hand. These processes are used as priors for object state distributions to learn dependent information between previous and current time steps. Markov chain Monte Carlo sampling methods exploit the learned information to sample from posterior distributions and update the estimated object parameters.
The second contribution proposes a novel, robust, and fast nonparametric approach based on a diffusion process over infinite random trees to infer information on object cardinality and trajectory. This method follows the hierarchy induced by objects entering and leaving a scene and the time-dependency between unknown object parameters. Markov chain Monte Carlo sampling methods integrate the prior distributions over the infinite random trees with time-dependent diffusion processes to update object states.
The third contribution develops the use of hierarchical models to form a prior for statistically dependent measurements in a single object tracking setup. Dependency among the sensor measurements provides extra information which is incorporated to achieve the optimal tracking performance. The hierarchical Dirichlet process as a prior provides the required flexibility to do inference. Bayesian tracker is integrated with the hierarchical Dirichlet process prior to accurately estimate the object trajectory.
The fourth contribution proposes an approach to model both the multiple dependent objects and multiple dependent measurements. This approach integrates the dependent Dirichlet process modeling over the dependent object with the hierarchical Dirichlet process modeling of the measurements to fully capture the dependency among both object and measurements. Bayesian nonparametric models can successfully associate each measurement to the corresponding object and exploit dependency among them to more accurately infer the trajectory of objects. Markov chain Monte Carlo methods amalgamate the dependent Dirichlet process with the hierarchical Dirichlet process to infer the object identity and object cardinality.
Simulations are exploited to demonstrate the improvement in multiple object tracking performance when compared to approaches that are developed based on random finite set theory.
The first contribution proposes dependent nonparametric models such as the dependent Dirichlet process and the dependent Pitman-Yor process to capture the inherent time-dependency in the problem at hand. These processes are used as priors for object state distributions to learn dependent information between previous and current time steps. Markov chain Monte Carlo sampling methods exploit the learned information to sample from posterior distributions and update the estimated object parameters.
The second contribution proposes a novel, robust, and fast nonparametric approach based on a diffusion process over infinite random trees to infer information on object cardinality and trajectory. This method follows the hierarchy induced by objects entering and leaving a scene and the time-dependency between unknown object parameters. Markov chain Monte Carlo sampling methods integrate the prior distributions over the infinite random trees with time-dependent diffusion processes to update object states.
The third contribution develops the use of hierarchical models to form a prior for statistically dependent measurements in a single object tracking setup. Dependency among the sensor measurements provides extra information which is incorporated to achieve the optimal tracking performance. The hierarchical Dirichlet process as a prior provides the required flexibility to do inference. Bayesian tracker is integrated with the hierarchical Dirichlet process prior to accurately estimate the object trajectory.
The fourth contribution proposes an approach to model both the multiple dependent objects and multiple dependent measurements. This approach integrates the dependent Dirichlet process modeling over the dependent object with the hierarchical Dirichlet process modeling of the measurements to fully capture the dependency among both object and measurements. Bayesian nonparametric models can successfully associate each measurement to the corresponding object and exploit dependency among them to more accurately infer the trajectory of objects. Markov chain Monte Carlo methods amalgamate the dependent Dirichlet process with the hierarchical Dirichlet process to infer the object identity and object cardinality.
Simulations are exploited to demonstrate the improvement in multiple object tracking performance when compared to approaches that are developed based on random finite set theory.
ContributorsMoraffah, Bahman (Author) / Papandreou-Suppappola, Antonia (Thesis advisor) / Bliss, Daniel W. (Committee member) / Richmond, Christ D. (Committee member) / Dasarathy, Gautam (Committee member) / Arizona State University (Publisher)
Created2019
Description
This dissertation centers on the development of Bayesian methods for learning differ- ent types of variation in switching nonlinear gene regulatory networks (GRNs). A new nonlinear and dynamic multivariate GRN model is introduced to account for different sources of variability in GRNs. The new model is aimed at more precisely capturing the complexity of GRN interactions through the introduction of time-varying kinetic order parameters, while allowing for variability in multiple model parameters. This model is used as the drift function in the development of several stochastic GRN mod- els based on Langevin dynamics. Six models are introduced which capture intrinsic and extrinsic noise in GRNs, thereby providing a full characterization of a stochastic regulatory system. A Bayesian hierarchical approach is developed for learning the Langevin model which best describes the noise dynamics at each time step. The trajectory of the state, which are the gene expression values, as well as the indicator corresponding to the correct noise model are estimated via sequential Monte Carlo (SMC) with a high degree of accuracy. To address the problem of time-varying regulatory interactions, a Bayesian hierarchical model is introduced for learning variation in switching GRN architectures with unknown measurement noise covariance. The trajectory of the state and the indicator corresponding to the network configuration at each time point are estimated using SMC. This work is extended to a fully Bayesian hierarchical model to account for uncertainty in the process noise covariance associated with each network architecture. An SMC algorithm with local Gibbs sampling is developed to estimate the trajectory of the state and the indicator correspond- ing to the network configuration at each time point with a high degree of accuracy. The results demonstrate the efficacy of Bayesian methods for learning information in switching nonlinear GRNs.
ContributorsVélez-Cruz, Nayely (Author) / Papandreou-Suppappola, Antonia (Thesis advisor) / Moraffah, Bahman (Committee member) / Tepedelenlioğlu, Cihan (Committee member) / Berisha, Visar (Committee member) / Arizona State University (Publisher)
Created2023