ASU Electronic Theses and Dissertations
This collection includes most of the ASU Theses and Dissertations from 2011 to present. ASU Theses and Dissertations are available in downloadable PDF format; however, a small percentage of items are under embargo. Information about the dissertations/theses includes degree information, committee members, an abstract, supporting data or media.
In addition to the electronic theses found in the ASU Digital Repository, ASU Theses and Dissertations can be found in the ASU Library Catalog.
Dissertations and Theses granted by Arizona State University are archived and made available through a joint effort of the ASU Graduate College and the ASU Libraries. For more information or questions about this collection contact or visit the Digital Repository ETD Library Guide or contact the ASU Graduate College at gradformat@asu.edu.
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- All Subjects: Archaeology
Description
Studies of ancient pathogens are moving beyond simple confirmatory analysis of diseased bone; bioarchaeologists and ancient geneticists are posing nuanced questions and utilizing novel methods capable of confronting the debates surrounding pathogen origins and evolution, and the relationships between humans and disease in the past. This dissertation examines two ancient human diseases through molecular and bioarchaeological lines of evidence, relying on techniques in paleogenetics and phylogenetics to detect, isolate, sequence and analyze ancient and modern pathogen DNA within an evolutionary framework. Specifically this research addresses outstanding issues regarding a) the evolution, origin and phylogenetic placement of the pathogen causing skeletal tuberculosis in New World prior to European contact, and b) the phylogeny and origins of the parasite causing the human leishmaniasis disease complex. An additional chapter presents a review of the major technological and theoretical advances in ancient pathogen genomics to frame the contributions of this work within a rapidly developing field. This overview emphasizes that understanding the evolution of human disease is critical to contextualizing relationships between humans and pathogens, and the epidemiological shifts observed both in the past and in the present era of (re)emerging infectious diseases. These questions continue to be at the forefront of not only pathogen research, but also
bioarchaeological and paleopathological scholarship.
bioarchaeological and paleopathological scholarship.
ContributorsHarkins, Kelly M (Author) / Buikstra, Jane E. (Thesis advisor) / Stone, Anne C (Thesis advisor) / Knudson, Kelly (Committee member) / Kumar, Sudhir (Committee member) / Krause, Johannes (Committee member) / Arizona State University (Publisher)
Created2014
Description
This dissertation examines the interrelationships between stress, frailty, growth, mortality, and diet at the Qinifab School site, Sudan, using a combination of osteological, paleopathological, and biogeochemical methods. The skeletal sample, from the fourth cataract region of Nubia, is comprised of 100 individuals from a Late Meroitic to Christian period (~250-1400 CE) cemetery. Standard osteological methods were used to estimate age and sex, and measurements were taken to assess body dimensions. Preadults were aged by dental and skeletal development, producing two independent ages to categorize individuals as developmentally “normal” or “delayed.” Data were collected on nonspecific indicators of stress, including linear enamel hypoplasias (LEHs), porotic hyperostosis (PH), and cribra orbitalia (CO). In preadults, these were compared to World Health Organization (WHO) growth standards to identify individuals who experienced stunting or wasting. For all ages, evidence of stress was compared with age at death and growth/body size. Finally, stable carbon and nitrogen isotope analyses were conducted on bone collagen and carbonate samples from a representative sample of 60 individuals, of which 46 collagen samples and all carbonates had acceptable preservation.“Delayed” preadults generally showed reduced body size relative to “normal” individuals, they were more likely to be stunted, and their growth trajectories were less similar to WHO standards. However, childhood stress had little impact on adult body size. CO occurred at higher frequencies in preadults and individuals with mixed/active lesions died at younger ages. PH rarely developed before age 6 but was present in most individuals over that age. Individuals with earlier formed LEHs tended to experience more stress overall and die younger. Active/mixed CO was associated with stunting in preadults and reduced brachial index in adults.
A greater proportion of individuals in the Christian period were affected by CO compared to the Post-Meroitic. A temporal shift also occurred in diet between the Post-Meroitic and Christian periods based upon the δ13CCOLL and δ15NCOLL values. Lower δ15N and the greater difference in δ13CAP-COLL suggest a shift toward intensified agriculture and decreased use of animal products and a potential dietary etiology for the increase in CO.
ContributorsNorris, Annie Laurie (Author) / Baker, Brenda J (Thesis advisor) / Knudson, Kelly (Committee member) / Dupras, Tosha (Committee member) / Arizona State University (Publisher)
Created2021
Description
This dissertation examines microevolutionary changes in the Eastern Adriatic and hinterland during Roman imperialism, evaluating changing patterns of variation among indigenous groups with varying histories of acceptance or defiance to Roman rule. Despite the prevalence of Roman influence, trade, and the accommodating nature of Roman political authority administered through existing local leaders, Eastern Adriatic and hinterland peoples underwent significant cultural transformations. Unlike the Roman-allied Liburnians, Romanization was not a voluntary and amicable process for the resisting Delmatae, Histri, Japodes, and Pannonians. The violent experiences of locals during the late Republican Period and early Roman Empire, including death, enslavement, conscription, and displacement, contrast with the eventual integration of the region by the end of the Roman Empire, when their descendants were Roman citizens. These complex histories make it challenging to understand local identities and the impact of Romanization. Biological distance analyses of dental morphology from Liburnian, Delmatae, Japodes, and Pannonian samples representing 313 individuals dating to the Iron Age (c. 700- 400 BCE), and Roman Period (Roman Republic c. 200- 0 BCE; Roman Empire c. 1- 500 CE), were contextualized with archaeological data and classical research. Results indicated no significant differences within Eastern Adriatic and hinterland populations across the time periods. However, interpretations of the results for Roman Period Liburnians, descendants of Roman allies, suggest differentiation from contemporaneous Italic Romans. Conversely, the descendants of resisting populations were not statistically different from Roman Empire Italics, potentially influenced by their ancestors’ experiences of war affecting subsequent admixture, community formation, and adherence to prevailing norms.
Roman laws that managed access to advantageous status identities through marriage and citizenship may also explain the findings that all surveyed local populations demonstrate continuity between ancestors and descendants. The dynamic of being identified as Roman, and yet descending from the people who fought against Rome, is further discussed as a form of biological imperialism, consequentially shaping indigenous ancestral ties within a pan-regional Roman citizenry. While Roman multiculturalism is often considered exemplary of Antique Period diversity, Roman values prioritized diversity when it was advantageous and used pluralism to encourage cultural assimilation and define outsiders.
ContributorsLoewen, Tisa Nicolette (Author) / Stojanowski, Christopher (Thesis advisor) / Buikstra, Jane (Committee member) / Novak, Mario (Committee member) / Knudson, Kelly (Committee member) / Arizona State University (Publisher)
Created2024