This collection includes most of the ASU Theses and Dissertations from 2011 to present. ASU Theses and Dissertations are available in downloadable PDF format; however, a small percentage of items are under embargo. Information about the dissertations/theses includes degree information, committee members, an abstract, supporting data or media.

In addition to the electronic theses found in the ASU Digital Repository, ASU Theses and Dissertations can be found in the ASU Library Catalog.

Dissertations and Theses granted by Arizona State University are archived and made available through a joint effort of the ASU Graduate College and the ASU Libraries. For more information or questions about this collection contact or visit the Digital Repository ETD Library Guide or contact the ASU Graduate College at gradformat@asu.edu.

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Description
In the artificial intelligence literature, three forms of reasoning are commonly employed to understand agent behavior: inductive, deductive, and abductive.  More recently, data-driven approaches leveraging ideas such as machine learning, data mining, and social network analysis have gained popularity. While data-driven variants of the aforementioned forms of reasoning have been applied

In the artificial intelligence literature, three forms of reasoning are commonly employed to understand agent behavior: inductive, deductive, and abductive.  More recently, data-driven approaches leveraging ideas such as machine learning, data mining, and social network analysis have gained popularity. While data-driven variants of the aforementioned forms of reasoning have been applied separately, there is little work on how data-driven approaches across all three forms relate and lend themselves to practical applications. Given an agent behavior and the percept sequence, how one can identify a specific outcome such as the likeliest explanation? To address real-world problems, it is vital to understand the different types of reasonings which can lead to better data-driven inference.  

This dissertation has laid the groundwork for studying these relationships and applying them to three real-world problems. In criminal modeling, inductive and deductive reasonings are applied to early prediction of violent criminal gang members. To address this problem the features derived from the co-arrestee social network as well as geographical and temporal features are leveraged. Then, a data-driven variant of geospatial abductive inference is studied in missing person problem to locate the missing person. Finally, induction and abduction reasonings are studied for identifying pathogenic accounts of a cascade in social networks.
ContributorsShaabani, Elham (Author) / Shakarian, Paulo (Thesis advisor) / Davulcu, Hasan (Committee member) / Maciejewski, Ross (Committee member) / Decker, Scott (Committee member) / Arizona State University (Publisher)
Created2019
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Description
The apolipoprotein E (APOE) e4 genotype is the most prevalent known genetic risk factor for Alzheimer's disease (AD). In this paper, we examined the longitudinal effect of APOE e4 on hippocampal morphometry in Alzheimer's Disease Neuroimaging Initiative (ADNI). Generally, atrophy of hippocampus has more chance occurs in AD patients who

The apolipoprotein E (APOE) e4 genotype is the most prevalent known genetic risk factor for Alzheimer's disease (AD). In this paper, we examined the longitudinal effect of APOE e4 on hippocampal morphometry in Alzheimer's Disease Neuroimaging Initiative (ADNI). Generally, atrophy of hippocampus has more chance occurs in AD patients who carrying the APOE e4 allele than those who are APOE e4 noncarriers. Also, brain structure and function depend on APOE genotype not just for Alzheimer's disease patients but also in health elderly individuals, so APOE genotyping is considered critical in clinical trials of Alzheimer's disease. We used a large sample of elderly participants, with the help of a new automated surface registration system based on surface conformal parameterization with holomorphic 1-forms and surface fluid registration. In this system, we automatically segmented and constructed hippocampal surfaces from MR images at many different time points, such as 6 months, 1- and 2-year follow up. Between the two different hippocampal surfaces, we did the high-order correspondences, using a novel inverse consistent surface fluid registration method. At each time point, using Hotelling's T^2 test, we found significant morphological deformation in APOE e4 carriers relative to noncarriers in the entire cohort as well as in the non-demented (pooled MCI and control) subjects, affecting the left hippocampus more than the right, and this effect was more pronounced in e4 homozygotes than heterozygotes.
ContributorsLi, Bolun (Author) / Wang, Yalin (Thesis advisor) / Maciejewski, Ross (Committee member) / Liang, Jianming (Committee member) / Arizona State University (Publisher)
Created2015