ASU Electronic Theses and Dissertations
This collection includes most of the ASU Theses and Dissertations from 2011 to present. ASU Theses and Dissertations are available in downloadable PDF format; however, a small percentage of items are under embargo. Information about the dissertations/theses includes degree information, committee members, an abstract, supporting data or media.
In addition to the electronic theses found in the ASU Digital Repository, ASU Theses and Dissertations can be found in the ASU Library Catalog.
Dissertations and Theses granted by Arizona State University are archived and made available through a joint effort of the ASU Graduate College and the ASU Libraries. For more information or questions about this collection contact or visit the Digital Repository ETD Library Guide or contact the ASU Graduate College at gradformat@asu.edu.
Filtering by
- All Subjects: Automatic control
- All Subjects: Spectral analysis
The thesis starts with a careful review of existing signal processing techniques and state of the art methods possible for vital signs monitoring using UWB impulse systems. Then an in-depth analysis of various approaches is presented.
Robust heart-rate monitoring methods are proposed based on a novel result: spectrally the fundamental heartbeat frequency is respiration-interference-limited while its higher-order harmonics are noise-limited. The higher-order statistics related to heartbeat can be a robust indication when the fundamental heartbeat is masked by the strong lower-order harmonics of respiration or when phase calibration is not accurate if phase-based method is used. Analytical spectral analysis is performed to validate that the higher-order harmonics of heartbeat is almost respiration-interference free. Extensive experiments have been conducted to justify an adaptive heart-rate monitoring algorithm. The scenarios of interest are, 1) single subject, 2) multiple subjects at different ranges, 3) multiple subjects at same range, and 4) through wall monitoring.
A remote sensing radar system implemented using the proposed adaptive heart-rate estimation algorithm is compared to the competing remote sensing technology, a remote imaging photoplethysmography system, showing promising results.
State of the art methods for vital signs monitoring are fundamentally related to process the phase variation due to vital signs motions. Their performance are determined by a phase calibration procedure. Existing methods fail to consider the time-varying nature of phase noise. There is no prior knowledge about which of the corrupted complex signals, in-phase component (I) and quadrature component (Q), need to be corrected. A precise phase calibration routine is proposed based on the respiration pattern. The I/Q samples from every breath are more likely to experience similar motion noise and therefore they should be corrected independently. High slow-time sampling rate is used to ensure phase calibration accuracy. Occasionally, a 180-degree phase shift error occurs after the initial calibration step and should be corrected as well. All phase trajectories in the I/Q plot are only allowed in certain angular spaces. This precise phase calibration routine is validated through computer simulations incorporating a time-varying phase noise model, controlled mechanic system, and human subject experiment.
existence of objects from which no direct information can be obtained
experimentally or observationally. A well known example is to
ascertain the existence of black holes of various masses in different
parts of the universe from indirect evidence, such as X-ray emissions.
In the field of complex networks, the problem of detecting
hidden nodes can be stated, as follows. Consider a network whose
topology is completely unknown but whose nodes consist of two types:
one accessible and another inaccessible from the outside world. The
accessible nodes can be observed or monitored, and it is assumed that time
series are available from each node in this group. The inaccessible
nodes are shielded from the outside and they are essentially
``hidden.'' The question is, based solely on the
available time series from the accessible nodes, can the existence and
locations of the hidden nodes be inferred? A completely data-driven,
compressive-sensing based method is developed to address this issue by utilizing
complex weighted networks of nonlinear oscillators, evolutionary game
and geospatial networks.
Both microbes and multicellular organisms actively regulate their cell
fate determination to cope with changing environments or to ensure
proper development. Here, the synthetic biology approaches are used to
engineer bistable gene networks to demonstrate that stochastic and
permanent cell fate determination can be achieved through initializing
gene regulatory networks (GRNs) at the boundary between dynamic
attractors. This is experimentally realized by linking a synthetic GRN
to a natural output of galactose metabolism regulation in yeast.
Combining mathematical modeling and flow cytometry, the
engineered systems are shown to be bistable and that inherent gene expression
stochasticity does not induce spontaneous state transitioning at
steady state. By interfacing rationally designed synthetic
GRNs with background gene regulation mechanisms, this work
investigates intricate properties of networks that illuminate possible
regulatory mechanisms for cell differentiation and development that
can be initiated from points of instability.