ASU Electronic Theses and Dissertations
This collection includes most of the ASU Theses and Dissertations from 2011 to present. ASU Theses and Dissertations are available in downloadable PDF format; however, a small percentage of items are under embargo. Information about the dissertations/theses includes degree information, committee members, an abstract, supporting data or media.
In addition to the electronic theses found in the ASU Digital Repository, ASU Theses and Dissertations can be found in the ASU Library Catalog.
Dissertations and Theses granted by Arizona State University are archived and made available through a joint effort of the ASU Graduate College and the ASU Libraries. For more information or questions about this collection contact or visit the Digital Repository ETD Library Guide or contact the ASU Graduate College at gradformat@asu.edu.
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- Creators: Davulcu, Hasan
Adverse Drug Reaction (ADR) identification. Such methods employ a step of drug search followed by classification of the associated text as consisting an ADR or not. Although this method works efficiently for ADR classifications, if ADR evidence is present in users posts over time, drug mentions fail to capture such ADRs. It also fails to record additional user information which may provide an opportunity to perform an in-depth analysis for lifestyle habits and possible reasons for any medical problems.
Pre-market clinical trials for drugs generally do not include pregnant women, and so their effects on pregnancy outcomes are not discovered early. This thesis presents a thorough, alternative strategy for assessing the safety profiles of drugs during pregnancy by utilizing user timelines from social media. I explore the use of a variety of state-of-the-art social media mining techniques, including rule-based and machine learning techniques, to identify pregnant women, monitor their drug usage patterns, categorize their birth outcomes, and attempt to discover associations between drugs and bad birth outcomes.
The technique used models user timelines as longitudinal patient networks, which provide us with a variety of key information about pregnancy, drug usage, and post-
birth reactions. I evaluate the distinct parts of the pipeline separately, validating the usefulness of each step. The approach to use user timelines in this fashion has produced very encouraging results, and can be employed for a range of other important tasks where users/patients are required to be followed over time to derive population-based measures.
Efficient processing of skyline queries on static data sources, data streams and incomplete datasets
An assumption commonly made by many skyline algorithms is that a skyline query is applied to a single static data source or data stream. Unfortunately, this assumption does not hold in many applications in which a skyline query may involve attributes belonging to multiple data sources and requires a join operation to be performed before the skyline can be produced. Recently, various skyline-join algorithms have been proposed to address this problem in the context of static data sources. However, these algorithms suffer from several drawbacks: they often need to scan the data sources exhaustively to obtain the skyline-join results; moreover, the pruning techniques employed to eliminate tuples are largely based on expensive tuple-to-tuple comparisons. On the other hand, most data stream techniques focus on single stream skyline queries, thus rendering them unsuitable for skyline-join queries.
Another assumption typically made by most of the earlier skyline algorithms is that the data is complete and all skyline attribute values are available. Due to this constraint, these algorithms cannot be applied to incomplete data sources in which some of the attribute values are missing and are represented by NULL values. There exists a definition of dominance for incomplete data, but this leads to undesirable consequences such as non-transitive and cyclic dominance relations both of which are detrimental to skyline processing.
Based on the aforementioned observations, the main goal of the research described in this dissertation is the design and development of a framework of skyline operators that effectively handles three distinct types of skyline queries: 1) skyline-join queries on static data sources, 2) skyline-window-join queries over data streams, and 3) strata-skyline queries on incomplete datasets. This dissertation presents the unique challenges posed by these skyline queries and addresses the shortcomings of current skyline techniques by proposing efficient methods to tackle the added overhead in processing skyline queries on static data sources, data streams, and incomplete datasets.