ASU Electronic Theses and Dissertations
This collection includes most of the ASU Theses and Dissertations from 2011 to present. ASU Theses and Dissertations are available in downloadable PDF format; however, a small percentage of items are under embargo. Information about the dissertations/theses includes degree information, committee members, an abstract, supporting data or media.
In addition to the electronic theses found in the ASU Digital Repository, ASU Theses and Dissertations can be found in the ASU Library Catalog.
Dissertations and Theses granted by Arizona State University are archived and made available through a joint effort of the ASU Graduate College and the ASU Libraries. For more information or questions about this collection contact or visit the Digital Repository ETD Library Guide or contact the ASU Graduate College at gradformat@asu.edu.
Filtering by
- All Subjects: Control
- Creators: Tsakalis, Konstantinos
In this study, the conditions of human seizures are recreated in an animal model of temporal lobe epilepsy. The rodents used in this study are chemically induced to become chronically epileptic. Their Electroencephalogram (EEG) data is then recorded and analyzed to detect and predict seizures; with the ultimate goal being the control and complete suppression of seizures.
Two methods, the maximum Lyapunov exponent and the Generalized Partial Directed Coherence (GPDC), are applied on EEG data to extract meaningful information. Their effectiveness have been reported in the literature for the purpose of prediction of seizures and seizure focus localization. This study integrates these measures, through some modifications, to robustly detect seizures and separately find precursors to them and in consequence provide stimulation to the epileptic brain of rats in order to suppress seizures. Additionally open-loop stimulation with biphasic currents of various pairs of sites in differing lengths of time have helped us create control efficacy maps. While GPDC tells us about the possible location of the focus, control efficacy maps tells us how effective stimulating a certain pair of sites will be.
The results from computations performed on the data are presented and the feasibility of the control problem is discussed. The results show a new reliable means of seizure detection even in the presence of artifacts in the data. The seizure precursors provide a means of prediction, in the order of tens of minutes, prior to seizures. Closed loop stimulation experiments based on these precursors and control efficacy maps on the epileptic animals show a maximum reduction of seizure frequency by 24.26\% in one animal and reduction of length of seizures by 51.77\% in another. Thus, through this study it was shown that the implementation of the methods can ameliorate seizures in an epileptic patient. It is expected that the new knowledge and experimental techniques will provide a guide for future research in an effort to ultimately eliminate seizures in epileptic patients.
used to produce three-phase sinusoidal voltages and currents from a DC source. They
are critical for injecting power from renewable energy sources into the grid. This is
especially true since many of these sources of energy are DC sources (e.g. solar
photovoltaic) or need to be stored in DC batteries because they are intermittent (e.g. wind
and solar). Two classes of inverters are examined in this thesis. A control-centric design
procedure is presented for each class. The first class of inverters is simple in that they
consist of three decoupled subsystems. Such inverters are characterized by no mutual
inductance between the three phases. As such, no multivariable coupling is present and
decentralized single-input single-output (SISO) control theory suffices to generate
acceptable control designs. For this class of inverters several families of controllers are
addressed in order to examine command following as well as input disturbance and noise
attenuation specifications. The goal here is to illuminate fundamental tradeoffs. Such
tradeoffs include an improvement in the in-band command following and output
disturbance attenuation versus a deterioration in out-of-band noise attenuation.
A fundamental deficiency associated with such inverters is their large size. This can be
remedied by designing a smaller core. This naturally leads to the second class of inverters
considered in this work. These inverters are characterized by significant mutual
inductances and multivariable coupling. As such, SISO control theory is generally not
adequate and multiple-input multiple-output (MIMO) theory becomes essential for
controlling these inverters.