ASU Electronic Theses and Dissertations
This collection includes most of the ASU Theses and Dissertations from 2011 to present. ASU Theses and Dissertations are available in downloadable PDF format; however, a small percentage of items are under embargo. Information about the dissertations/theses includes degree information, committee members, an abstract, supporting data or media.
In addition to the electronic theses found in the ASU Digital Repository, ASU Theses and Dissertations can be found in the ASU Library Catalog.
Dissertations and Theses granted by Arizona State University are archived and made available through a joint effort of the ASU Graduate College and the ASU Libraries. For more information or questions about this collection contact or visit the Digital Repository ETD Library Guide or contact the ASU Graduate College at gradformat@asu.edu.
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- All Subjects: Statistics
- Creators: Li, Jing
- Creators: Davulcu, Hasan
In this thesis, several data mining algorithms have been applied to analyze students’ code assignment submission data from a real classroom study. The goal of this work is to explore
and predict students’ performances. Multiple machine learning models and the model accuracy were evaluated based on the Shapley Additive Explanation.
The Cross-Validation shows the Gradient Boosting Decision Tree has the best precision 85.93% with average 82.90%. Features like Component grade, Due Date, Submission Times have higher impact than others. Baseline model received lower precision due to lack of non-linear fitting.
The first topic is a Mixed Effects Transfer Learning (METL) model that can flexibly incorporate mixed effects and a general-form covariance matrix to better account for similarity and heterogeneity across subjects. I further develop computationally efficient procedures to handle unknown parameters and large covariance structures. Domain relations, such as domain similarity and domain covariance structure, are automatically quantified in the estimation steps. I demonstrate METL in an application of smartphone-based telemonitoring of PD.
The second topic focuses on an MRI-based transfer learning algorithm for non-invasive surgical guidance of glioblastoma patients. Limited biopsy samples per patient create a challenge to build a patient-specific model for glioblastoma. A transfer learning framework helps to leverage other patient’s knowledge for building a better predictive model. When modeling a target patient, not every patient’s information is helpful. Deciding the subset of other patients from which to transfer information to the modeling of the target patient is an important task to build an accurate predictive model. I define the subset of “transferrable” patients as those who have a positive rCBV-cell density correlation, because a positive correlation is confirmed by imaging theory and the its respective literature.
The last topic is a Privacy-Preserving Positive Transfer Learning (P3TL) model. Although negative transfer has been recognized as an important issue by the transfer learning research community, there is a lack of theoretical studies in evaluating the risk of negative transfer for a transfer learning method and identifying what causes the negative transfer. My work addresses this issue. Driven by the theoretical insights, I extend Bayesian Parameter Transfer (BPT) to a new method, i.e., P3TL. The unique features of P3TL include intelligent selection of patients to transfer in order to avoid negative transfer and maintain patient privacy. These features make P3TL an excellent model for telemonitoring of PD using an At-Home Testing Device.
This research explores the problem of the why so few of the published algorithms enter production and furthermore, fewer end up generating sustained value. The dissertation proposes a ‘Design for Deployment’ (DFD) framework to successfully build machine learning analytics so they can be deployed to generate sustained value. The framework emphasizes and elaborates the often neglected but immensely important latter steps of an analytics process: ‘Evaluation’ and ‘Deployment’. A representative evaluation framework is proposed that incorporates the temporal-shifts and dynamism of real-world scenarios. Additionally, the recommended infrastructure allows analytics projects to pivot rapidly when a particular venture does not materialize. Deployment needs and apprehensions of the industry are identified and gaps addressed through a 4-step process for sustainable deployment. Lastly, the need for analytics as a functional area (like finance and IT) is identified to maximize the return on machine-learning deployment.
The framework and process is demonstrated in semiconductor manufacturing – it is highly complex process involving hundreds of optical, electrical, chemical, mechanical, thermal, electrochemical and software processes which makes it a highly dynamic non-stationary system. Due to the 24/7 uptime requirements in manufacturing, high-reliability and fail-safe are a must. Moreover, the ever growing volumes mean that the system must be highly scalable. Lastly, due to the high cost of change, sustained value proposition is a must for any proposed changes. Hence the context is ideal to explore the issues involved. The enterprise use-cases are used to demonstrate the robustness of the framework in addressing challenges encountered in the end-to-end process of productizing machine learning analytics in dynamic read-world scenarios.
The first topic is an embedded feature selection algorithm termed Expectation-Selection-Maximization (ESM) model that can automatically select features while optimizing the parameters for Gaussian Mixture Model. I introduce a relevancy index (RI) revealing the contribution of the feature in the clustering process to assist feature selection. I demonstrate the efficacy of the ESM by studying two synthetic datasets, four benchmark datasets, and an Alzheimer’s Disease dataset.
The second topic focuses on extending the application of ESM algorithm to handle mixed datatypes. The Gaussian mixture model is generalized to Generalized Model of Mixture (GMoM), which can not only handle continuous features, but also binary and nominal features.
The last topic is about Uncertainty Quantification (UQ) of the feature selection. A new algorithm termed ESOM is proposed, which takes the variance information into consideration while conducting feature selection. Also, a set of outliers are generated in the feature selection process to infer the uncertainty in the input data. Finally, the selected features and detected outlier instances are evaluated by visualization comparison.
The main objective of this work is to investigate and improve measurement policies on the basis of quality control in the transduction/expansion bio-manufacturing processes. More specifically, this study addresses the issue of measuring yield within the transduction/expansion phases of gene therapy. To do so, it was decided to model the process as a Markov Decision Process where the decisions being made are optimally chosen to create an overall optimal measurement policy; for a set of predefined parameters.