ASU Electronic Theses and Dissertations
This collection includes most of the ASU Theses and Dissertations from 2011 to present. ASU Theses and Dissertations are available in downloadable PDF format; however, a small percentage of items are under embargo. Information about the dissertations/theses includes degree information, committee members, an abstract, supporting data or media.
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- All Subjects: Health Sciences
- Creators: Gaesser, Glenn A
et cycling efficiency in young (18-59 years old) and older (60-81 years old) adults (N=444). Walking was performed at three miles per hour by 86 young (mean = 29.60, standard deviation (SD) = 10.50 years old) and 121 older adults (mean = 66.80, SD = 4.50 years old). Cycling at 50 watts (60-70 revolutions per minute) was performed by 116 young (mean= 29.00, SD= 10.00 years old) and 121 older adults (m = 67.10 SD = 4.50 years old). Steady-state sub-maximal gross
et oxygen uptake and caloric expenditures from each activity and rest were analyzed. Net walking economy was represented by net caloric expenditure (kilocalories/kilogram/min). Cycling measures included percent gross
et cycling efficiency (kilo-calorie derived). Linear regressions were used to assess each measure as a function of age. Differences in age group means were assessed using independent t-tests for each modality (alpha = 0.05). No significant differences in mean oxygen uptake nor walking economy were found between young and older walkers (p>0.05). Older adults performing cycle ergometry demonstrated lower gross
et oxygen uptakes and lower gross caloric expenditures (p< 0.05).
Purpose: To evaluate the acute effects of a 15-min postmeal walk on glucose control and markers of oxidative stress following a high-carbohydrate meal.
Methods: Ten obese subjects (55.0 ± 10.0 yrs) with impaired fasting glucose (107.1 ± 9.0 mg/dL) participated in this repeated measures trial. Subjects arrived at the laboratory following an overnight fast and underwent one of three conditions: 1) Test meal with no walking or fiber (CON), 2) Test meal with 10g fiber and no walking (FIB), 3) Test meal with no fiber followed by a 15-min treadmill walk at preferred walking speed (WALK). Blood samples were taken over four hours and assayed for glucose, insulin, thiobarbituric reactive substances (TBARS), catalase, uric acid, and total antioxidant capacity (TAC). A repeated measures ANOVA was used to compare mean differences for all outcome variables.
Results: The 2hr and 4hr incremental area under the curve (iAUC) for glucose was lower in both FIB (2hr: -93.59 mmol∙120 min∙L-1, p = 0.006; 4hr: -92.59 mmol∙240 min∙L-1; p = 0.041) and WALK (2hr: -77.21 mmol∙120 min∙L-1, p = 0.002; 4hr: -102.94 mmol∙240 min∙L-1; p = 0.005) conditions respectively, compared with CON. There were no differences in 2hr or 4hr iAUC for glucose between FIB and WALK (2hr: p = 0.493; 4hr: p = 0.783). The 2hr iAUC for insulin was significantly lower in both FIB (-37.15 μU ∙h/mL; p = 0.021) and WALK (-66.35 μU ∙h/mL; p < 0.001) conditions, compared with CON, and was significantly lower in the WALK (-29.2 μU ∙h/mL; p = 0.049) condition, compared with FIB. The 4hr iAUC for insulin in the WALK condition was significantly lower than both CON (-104.51 μU ∙h/mL; p = 0.001) and FIB (-77.12 μU ∙h/mL; p = 0.006) conditions. Markers of oxidative stress were not significantly different between conditions.
Conclusion: A moderate 15-minute postmeal walk is an effective strategy to reduce postprandial hyperglycemia. However, it is unclear if this attenuation could lead to improvements in postprandial oxidative stress.