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- Creators: School of Politics and Global Studies
Description
Schizophrenia affects 1.1% of the population worldwide. Schizophrenia is a complex, multifactorial disorder. Stress can trigger psychotic episodes and exacerbate schizophrenic symptoms. For humans, one gene implicated in stress and schizophrenia in humans is the early growth response 3 (EGR3). Patients with genomic variations in EGR3 have reduced levels of EGR3 in the prefrontal brain region compared with healthy patients. Schizophrenic patients also have less serotonin 2A receptor (5HT2AR), which is coded by the gene Htr2a, in their prefrontal cortex. Mice that are Egr3-deficient also have decreased levels of 5HT2AR, suggesting that Egr3 may be involved in the regulation of 5HT2AR. The purpose of the experiment is to determine if EGR3 binds to the Htr2a gene promoter region by using a Chromatin immunoprecipitation (ChIP) assay. We will use ECS to increase EGR3 expression. Previously we have identified two upstream sites of interest where EGR3 potentially binds to the Htr2a gene, one which is distal and one proximal to the transcription start site. After ECS, increased binding is seen in the Htr2a distal region with EGR3 via the ChIP assay. Increased binding was not observed at either of the promoter sites; however, the t-test comparing the distal site of the ECS and the No ECS groups to have a p-value of 0.056, suggesting that increasing the number of animals (n=7) could possibly give a more accurate representation to test our hypothesis. However, the experiment still suggests increased expression and that EGR3 may bind to the distal site of Htr2a. Keywords: stress, environment, genetics, schizophrenia, EGR3, chromatin immunoprecipitation
ContributorsMishra, Abhinav (Author) / Buetow, Kenneth (Thesis director) / Gallitano, Amelia (Committee member) / Zhao, Xiuli (Committee member) / Barrett, The Honors College (Contributor) / School of Politics and Global Studies (Contributor) / School of Life Sciences (Contributor)
Created2015-05
Description
Within sixty years, the People’s Republic of China has risen from a struggling post-civil war state to the second largest economy in the world, comprising of 16.71 percent of the global economy as of 2015. While China has grown, its presence internationally has grown as well—China has utilized its capital to foment important relationships and foster soft power dynamics, making billions available in development aid and investment projects across the globe, most notably in Africa and Latin America, where Chinese goods have begun to dominate the markets there as they have in American counterparts. However, within Latin America China has been investing in countries that are traditionally seen as “risky” financial investments. This paper hypothesizes that the returns on Chinese investments in Latin America are not financial, but political—that China is investing in expansion of its soft-power and legitimizing its beginnings of global hegemony. The paper also explores the success of these initiatives by comparing the level of Chinese investment to changes in Latin American foreign policy alignment, discourse, and agreements through utilizing case studies of Venezuela and Bolivia.
ContributorsHochhaus, Natalie (Co-author) / Yan, Jaylia (Co-author) / Thomson, Henry (Thesis director) / Ripley, Charles (Committee member) / School of Politics and Global Studies (Contributor) / Department of Economics (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
Faërie exists in the mythology and literature of northwestern Europe as a spiritual Otherworld, a land of immortal beauty just tangential to our own. This project explored multiple conceptions of Faërie and their common association with things that have been lost. The pattern that emerged is one in which the Otherworld is not merely linked to lost things, but becomes a way of preserving and rediscovering them. Faërie embodies the hope that things lost live on, and can be found again.
ContributorsBell, Andrew Roos (Author) / Baldini, Cajsa (Thesis director) / Maring, Heather (Committee member) / Foy, Joseph (Committee member) / Barrett, The Honors College (Contributor) / School of Politics and Global Studies (Contributor) / Department of English (Contributor)
Created2013-05
Description
This paper examines how China was able to influence modernization in Southeast Asia during the time period of 1980-1995. Following thirty years of isolation, China opened itself up to foreign investments in an effort to modernize the country. Comparing the inflows and outflows of investment between China, Hong Kong, Singapore, Malaysia, and the Philippines, the impact on industries can be seen. China opening itself up to the world served as a catalyst for the region and helped lead to development and modernization in each country examined.
ContributorsVan Streain, Taylor Andrew (Author) / Mendez, Jose (Thesis director) / Rush, James (Committee member) / Barrett, The Honors College (Contributor) / Department of Economics (Contributor) / W. P. Carey School of Business (Contributor) / School of Social and Behavioral Sciences (Contributor) / School of Politics and Global Studies (Contributor)
Created2014-05
Description
This piece highlights the Trump administration's history of diplomatic relations with states in East Asia (specifically North Korea (DPRK), South Korea (ROK), Japan, and China). The research in this essay primarily focuses on Trump's public attitudes towards these states during his presidential campaign, and seeks to establish if any negative statements towards East Asian states have affected social and diplomatic relations after Trump's inauguration. Overall, residents of Japan and South Korea had an overwhelmingly negative view of Trump during his campaign, primarily due to cultural differences and dissatisfaction with Trump's blunt, unpredictable demeanor which clashes with Japanese and Korean social norms. While public opinion of Trump was still low in mainland China, Trump's attitude is reminiscent of Mao Zedong's Cultural Revolution which serves as the societal and governmental framework of the modern People's Republic of China. Therefore, individuals living in China were more likely to be attracted to Trump's personality \u2014 this evident through the popularity of Trump "fan clubs" which gained popularity on Chinese social media websites during the American presidential campaign period. In terms of the bilateral relations between the U.S. and each East Asian state, Donald Trump's negative statements towards China, Japan, and South Korea during his campaign did not significantly impact diplomatic relations during his presidency. While Trump is vocally opposed to certain initiatives that are supported by these heads of state, he has demonstrated a willingness to discuss issues with these leaders. While this openness is not completely evident in U.S. \u2014 Southeast Asian relations, the leaders of Northeast Asia have set aside Trump's controversial campaign statements and have reciprocated his willingness to discuss important issues.
ContributorsGarvey, Lauren Agnes (Author) / Simon, Sheldon (Thesis director) / Ripley, Charles (Committee member) / School of Politics and Global Studies (Contributor) / School of Public Affairs (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
The Chinese tourism market has become the largest tourism market in the world and continues to show promise in its future development. Global destinations such as Southeast Asia, France and now Australia have begun to see a major boom in Chinese tourists within the past decade due to less restrictive travel policies, a growing economy and higher disposable income rates within urban centers in China. Australia has become the top destination among Chinese citizens that wish to travel due to its coastal and beach attractions, unique wildlife, and general welcoming attitude toward Chinese citizens. As the market continues to grow, the characteristics and demographics change as well. The Chinese government did not allow for international travel until the early 1990s. During this time, package tours offered by government-regulated travel agencies were the prominent method of travel planning with travelers over the age of 35 making up the majority of travelers. However, in the past decade there has been a shift from group travel toward independent travel due to higher income and more independence among young adults. There remains a stigma against Chinese tourists due to behavioral and cultural challenges Chinese tourists face when traveling abroad, but as Chinese travelers begin to travel in smaller groups and have greater exposure to international cultures, these negative stereotypes will start to disappear. This paper focuses on the impact the Chinese tourism market has on Cairns, Australia. Cairns is characterized by its backpacking culture, easy access to environmental attractions and a high number of annual travelers from Asia and China specifically. The paper uses qualitative research and compiles information from news sources, government documents and statistical data regarding Chinese outbound tourism and its impacts on Australian tourism. There is also a case study composed of personal observations of a nature park in North Queensland which uses specific marketing and attraction coordination to appeal to Chinese tourists. This case study analyzes the tactics used by local destinations that cater to group travel over independent travel and points out the benefits of this type of specialized tourism. The research concludes by arguing the trend toward independent travel is beneficial to the Cairns tourism industry rather than harmful as long as the industry recognizes the new trends in Chinese tourism and does not focus on the previous trends of group travel when appealing to Chinese tourists. Instead, the industry should continue to focus on the backpacking culture and work toward catering to the demands of millennial travelers.
ContributorsRochon, Jacob Henri (Author) / Goodman, Rebekka (Thesis director) / McWilliams, Claire (Committee member) / College of Public Service and Community Solutions (Contributor) / School of Politics and Global Studies (Contributor) / School of International Letters and Cultures (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
Description
Pizza, Pasta, Parmesan, this is Italian cuisine? What is conceived by many to be Italian cuisine and way of life is actually a glamorized and artificial unification of a multitude of different regional sub-cultures. The aim of my project was to provide a means through which other students can come to understand the diversity and complexities that make up the Italian culture and cuisine. The way in which this is to be accomplished was through the creation of a syllabus for a course here at ASU. The project aims to encourage students to think critically about the Italian lifestyle and how food and culture are interrelated. It is imperative that stereotypes surrounding the Italian culture are broken down and for the culture to be understood through a new lens. The manner through which Italian culture is examined rests upon the culture's impact on cuisine and the cuisine's impact on the culture. Italy's connections to the Mediterranean are explored through the cultural impacts of exchange and the scientific evidence behind the Mediterranean Diet. It is critical to consider cuisine when attempting to understand the history and culture of a location. Prezzolini's quote, "what is the glory of Dante compared to spaghetti?" was the starting point to which the questions surrounding the importance of cuisine were considered. One of the most important goals was to foster self-reflection and growth. As many of the texts challenge the preconceptions that most American maintain about Italian society, it is imperative that students reflect upon their own cultures and biases. For a course to have a meaningful impact upon the students the students must take something away from the course. The method of analysis was an analysis of the texts given the goals of the syllabus expressed through the learning outcomes. I concluded that the syllabus overall was sound. There was a wealth of texts which were unbiased or provided ample critiques to other readings. The texts also encourage students to reflect upon their own cultures and beliefs.
ContributorsHallquist, Jessika Anne (Author) / Vitullo, Juliann (Thesis director) / Minardi, Enrico (Committee member) / School of Politics and Global Studies (Contributor) / School of International Letters and Cultures (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
Description
This study examines sustainable development concerns as an essential part of the Costa Rican national identity. Interviews with ecotourism industry workers and an analysis of pertinent news articles shine light on the Costa Rican citizen's perspective of sustainable development, showing that in spite of current initiatives industry workers still have unmet environmental and economic concerns, and that the general public is both passionately interested and personally invested in the topic.
ContributorsHoward, Kalyn Marie (Author) / Puleo, Thomas (Thesis director) / Larson, Elizabeth (Committee member) / Hunter, Joel (Committee member) / Barrett, The Honors College (Contributor) / School of Humanities, Arts, and Cultural Studies (Contributor) / School of Politics and Global Studies (Contributor)
Created2013-05
Description
A Foreigner's Guide to China, a creative project, is a short novel that blends cultural analysis and linguistic study in a collective investigation of modern China. As China grows at an unprecedented pace, many Americans still remain ignorant of life and development in a foreign place on the other side of the world. The project is an attempt to help mesh cultural lines and aid students, travelers, and businesspeople travelling to China for the first time. Therefore, the main goal of the entire project is to provide an actual guidebook that can be read prior to going to China or while in the country. The project is divided into two main types of chapters: cultural analysis and advice giving on day to day life in China, and linguistic study that adopts a more academic approach. Both types of chapters use my personal anecdotes to give both context and a sense of reality to the advice I include in the project. While very different in their styles, the two types of chapters ultimately work towards the same end: explaining differences and similarities between Chinese and American cultures, and giving a cultural opening from which to expand understanding. The novel is written in a lighthearted and humorous tone that attempts to soften the often seemingly offensive overtone that appears when analyzing cultures side by side. Topics include landing advice, transportation, cuisine, working life, and school life, as well as Mandarin Chinese tones, politeness, and dialects. Overall, the project has a more cultural outlook with a heavier focus on those sections.
ContributorsDaliere, Andrew John (Author) / Oh, Young (Thesis director) / Lyon, Mich (Committee member) / W. P. Carey School of Business (Contributor) / School of International Letters and Cultures (Contributor) / School of Politics and Global Studies (Contributor) / Barrett, The Honors College (Contributor)
Created2015-12
Description
Located in the Putuo District of Shanghai, Caoyang New Village is an anomaly of sorts from the perspective of contemporary Chinese urban planning. With a history dating back to the early Mao era, the village has long been a symbol of socialist urban imagery that seems ahead of its time because in many ways it displays contemporary "new urbanism" elements. This paper discusses the origins and history of Caoyang Workers' Village, moving forward to its present conditions and recent role as an urban site for participatory planning. It also considers future redevelopment plans for Caoyang New Village, touching upon current conflict over the preservation of its cultural heritage and the need to address its housing issues. In analyzing the past and present of Caoyang New Village, questions of its future as a unique entity within modernity-seeking Shanghai arise.
ContributorsCristelli, Gabrielle Elizabeth (Author) / Webster, Douglas (Thesis director) / Sivak, Henry (Committee member) / School of Politics and Global Studies (Contributor) / School of International Letters and Cultures (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05