Matching Items (386)
Description
Abortion is one of the most polarizing moral issues in our society today. This issue divides the country into two separate groups: Pro-choice or Pro-life. Our thesis analyzes published reviewed articles, media articles, policy papers, and perspective, opinion, and commentary pieces to discuss the ethical implications of selective abortion, specifically sex-selective abortion and genetic-selective abortion. Our thesis provides an overview of selective abortion, explores women’s bodily autonomy in the U.S., addresses the complexities of both sex-selective and genetic-selective abortion, and finally evaluates the U.S.’s regulation of selective abortion. Through these topics, we were able to determine the implications selective abortion has on the disabled community and how selective abortion is being used to ban abortion overall in the U.S.
ContributorsNguyen, Nhu Quynh (Co-author) / McNeill, Ashley (Co-author) / Brian, Jennifer (Thesis director) / Manninen, Bertha (Committee member) / Department of Psychology (Contributor) / School of Life Sciences (Contributor) / Watts College of Public Service & Community Solut (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
Description
Germany, a Western-European country famous for its beer, pretzels, and beautiful castles, is rated among the top countries in the world for quality public education and health care with a population of around 82,927,922 (U.S. News, 2019). While Germany is typically seen as a very progressive country, where do they stand when it comes to women in the business world? German women have the same rights as men, but do they have the same opportunities? My research aimed to find out whether traditional gender roles in Germany still impact businesswomen to this day. As an American woman, who one day hopes to work in sales in the private sector, I was curious as to what it would be like if I were to live in Germany. This was especially interesting to me as a Business Management and German student who also was an exchange student in Germany during high school. Throughout my research I gathered a plethora of information about traditional German gender roles, the current situation for German business women, and what the hope for the future is. (abstract)
ContributorsCampton, Sydney (Author) / LaRosa, Julia (Thesis director) / Reves, Christiane (Committee member) / Dean, W.P. Carey School of Business (Contributor) / Department of Management and Entrepreneurship (Contributor) / Watts College of Public Service & Community Solut (Contributor) / School of International Letters and Cultures (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
Description
As technological advancement increases and becomes more accessible to everyone around the world, many communities and support groups have begun to offer online options for their programs, whether it be a fitness program, online therapy group, or doctor’s appointment. With the COVID-19 pandemic affecting every country around the world, online and virtual communities have become more necessary than ever. Using personal experience from an online fitness community formed as a response to social isolation called“Barrett Healthy Minds, Healthy Bodies,” research was conducted to determine if online communities had the same effectiveness as in-person communities in reaching and maintaining individual health goals. Peer-reviewed scientific articles and research papers from many countries around the world were analyzed for demonstration and quantification of the efficacy of other online communities compared to in- person groups. In addition, the benefits and limitations of online communities were identified. Using all of the research and data collected, a novel fitness program was designed for implementation with an online synchronous group (OSG) and an online asynchronous option serving as a control to observe any differential adherence of participants to fitness goals. The proposed OSG consists of meetings and workouts through Zoom and is more interactive, even virtually. The control group had no interaction with others and completed the workouts alone. While this program was not distributed to the public and tested as part of this project, it was designed to be an optimized pilot program to test the impact of remote community engagement on goal attainment. It is predicted that the OSG would demonstrate improvement over control in better reaching goals and increased satisfaction with results. Scientific literature from a variety of disciplines discussed here informs this prediction.
ContributorsKaroubi, Seema (Author) / Sellner, Erin (Thesis director) / Culbertson, Jade (Committee member) / School of Humanities, Arts, and Cultural Studies (Contributor) / School of Mathematical and Natural Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
Description
Rainbowfish, Melanotaenia splendida, are a common freshwater species in tropical regions of the world. They are members of the Atheriniformes (Atherinomorpha), the silverside fishes, which are known for some unusual feeding behaviors. Their close relatives, the Cypriniformes, such as mollies, guppies, and mosquitofish, are well studied and exhibit innovative morphologies associated with feeding. The third member of the Atherinomorphs, the Beloniformes, contains the recognizably odd needlefish, halfbeaks, and flying fishes. As a group, it is fair to say that the Atherinomorpha contain some pretty unusual fishes. The purpose of this project was to gain a further understanding of the unique feeding kinematics of Atheriniform fishes using the rainbowfish as an exemplar species. Feeding kinematics were quantified using high speed video recording unrestrained feeding events. Three feeding events from five individuals were analyzed frame by frame, from the time of the mouth opening to mouth closing. The X,Y coordinates of seven specific points were used to calculate the following kinematic variables: cranial elevation, gape distance, premaxillary protrusion, and hyoid depression. The contribution of cranial elevation to the strike was inconsistent. At times the fish raised the head as they expanded the mouth for prey capture, and at other times they did not. Cranial elevation is theoretically important for expanding the head during suction prey capture. Hyoid depression was more consistent, and clearly contributed to expansion of the head elements. Premaxillary protrusion contributed strongly to the event, and the jaws are closed with the premaxilla still protruded, facilitating a ‘nipping’ style jaw closure. A nipping style of prey capture is much like the Cyprinodontiforms, however, in rainbowfish, the event was quicker, and appeared to rely heavily on suction. We used both cleared and stained specimens and CT scans to investigate the underlying morphology of rainbowfish. These images revealed nearly microscopic teeth on the exterior of the jaws, and other features associated with feeding on highly elusive prey (i.e. prey that are mobile and likely to be able to escape predation). Further examination revealed a surprisingly well developed set of pharyngeal jaws, secondary to the oral jaws. The structure of the pharyngeal jaws suggested that most of the prey processing occurred within the pharynx.
ContributorsLerma, Sarahi (Author) / Ferry, Lara A. (Thesis director) / Hackney Price, Jennifer (Committee member) / Barrett, The Honors College (Contributor) / School of Mathematical and Natural Sciences (Contributor) / School of Social and Behavioral Sciences (Contributor)
Created2015-05
Description
This paper focuses on feudalist structure and values within this system in George R. R. Martin's fantasy novel series A Song of Ice and Fire and Shakespeare's play King Richard the Third. The paper is structured into three arguments that focus on different characters from each work. The first argument is focused on Tyrion Lannister and Richard III's deformity, and how they violate feudalist values. This argument ultimately comes to the discussion of whether or not these characters are monstrous and by what values. The second argument is focused on Daenerys Targaryen and Margaret, discussing why both authors give these women a supernatural power. The authors give women these powers because they believe that women should have power. Martin argues that women need to remake the structure, while Shakespeare believes women can change their place in the structure through collective action. The last argument focuses on Petyr Baelish and Richard III, and how they both represent a chaos attacking feudalism. Petyr is a chaos that comes outside the system, exploiting the values of the system, while Richard is a chaos within the system because he violates feudal values, while trying to hold positions where he needs to embody feudalist value. The authors come to different conclusions of what is trying to take down feudalist structure and how this could be fixed. Martin finds feudalism cannot be fixed and that other systems are not much better because they still create violence. Shakespeare comes to the conclusion that feudalism cannot be fixed because people continue to violate its values, so a new system must be put in place.
ContributorsPittaro, James Vincent (Author) / Mann, Annika (Thesis director) / Kirsch, Sharon (Committee member) / Barrett, The Honors College (Contributor) / School of Social and Behavioral Sciences (Contributor) / School of Humanities, Arts, and Cultural Studies (Contributor)
Created2015-05
Description
Bexarotene (Targretin®) is an FDA approved drug used to treat cutaneous T-cell lymphoma (CTCL), as well as off-label treatments for various cancers and neurodegenerative diseases. Previous research has indicated that bexarotene has a specific affinity for retinoid X receptors (RXR), which allows bexarotene to act as a ligand-activated-transcription factor and in return control cell differentiation and proliferation. Bexarotene targets RXR homodimerization to drive transcription of tumor suppressing genes; however, adverse reactions occur simultaneously when bound to other nuclear receptors. In this study, we used novel bexarotene analogs throughout 5 iterations synthesized in the laboratory of Dr. Wagner to test for their potency and ability to bind RXR. The aim of our study is to quantitatively measure RXR homodimerization driven by bexarotene analogs using a yeast two-hybrid system. Our results suggests there to be several compounds with higher protein activity than bexarotene, particularly in generations 3.0 and 5.0. This higher affinity for RXR homodimers may help scientists identify a compound that will minimize adverse effects and toxicity of bexarotene and serve as a better cancer treatment alternative.
ContributorsSeto, David Hua (Author) / Marshall, Pamela (Thesis director) / Wagner, Carl (Committee member) / Barrett, The Honors College (Contributor) / School of Mathematical and Natural Sciences (Contributor) / School of Social and Behavioral Sciences (Contributor)
Created2015-05
Description
Civic engagement is often defined as political activism; to be a part of governmental decision making, the practices thereof, and various efforts of participation in voting. However, civic engagement is also known for its role within non-political work, such as community building and development. Because of the former definition many members of our society have a tendency to not embrace the full potential of their community roles. It is always about who is a Republican, who is a Democrat, who looks better, or who has a better name. Now it must be noted that this is not in absolute, not all members of our society work in this thought process, but many still do. If that doesn't come as a surprise to you, then the simplicity of how you can be an engaged member will. As a student attending Arizona State University at the West campus in Phoenix, Arizona, I have chosen to challenge the traditional view of civic engagement and prepare this development plan for the campus community. Having done so, I not only discovered the paths that one can take to be engaged in such matters, but also continued my role as a civil servant.
ContributorsWaldie, Howard William (Author) / Ackroyd, William (Thesis director) / Smith, Sharon (Committee member) / Alvarez Manninen, Bertha (Committee member) / Barrett, The Honors College (Contributor) / School of Social and Behavioral Sciences (Contributor) / School of Humanities, Arts, and Cultural Studies (Contributor)
Created2015-05
Description
"The Hunger Games: What a Dystopic World Reveals about Modern Society" is an interdisciplinary thesis that examines the impossibility of revolutionary stories or concepts in popular culture by specifically analyzing the Hunger Games project. First, an analysis of what young adult fiction is and how it is written is provided. The formulaic way in which modern adolescent literature is written provides the basic structure for Suzanne Collins' Hunger Games trilogy. The second chapter examines the main character of the Hunger Games series, Katniss Everdeen. The way in which this young female heroine relinquishes her independence and courage due to being consistently undermined by the men and political leaders in her life is traced by following the development of the story throughout the three novels. The third chapter of the thesis delves into how the entire Hunger Games project of novels and films fits into current popular culture. An analysis of the mass production of the novels, and then turning the books into films, merchandise, and further commercialization of the story is discussed in detail throughout the chapter. Finally, the thesis discusses the responsibility authors of young adult literature should assume when addressing a young impressionable audience and how Collins took advantage of the position she had in telling the story of Katniss Everdeen.
ContributorsHeath, Elisabeth Rose (Author) / Gruber, Diane (Thesis director) / Bixby, Patrick (Committee member) / Roy, Sohinee (Committee member) / Barrett, The Honors College (Contributor) / School of Social and Behavioral Sciences (Contributor) / School of Humanities, Arts, and Cultural Studies (Contributor)
Created2015-05
Description
Multiracial individuals are the fastest growing demographic group in the United States. In order to explore and gain insight into how mixed-race individuals understand and negotiate their identity, this project includes a documentary of compiled interviews with multiracial individuals. These interviews seek to address both positive and problematic notions associated with identifying as mixed race/multi-ethnic, including issues that these individuals encounter if, and when, the dominant culture rejects their blended racial heritage. The video format allows individuals to convey the complicated nature of belonging to different groups of people that are hierarchically divided in the United States.
ContributorsCavazos, Amanda Catherine (Author) / Elenes, C. Alejandra (Thesis director) / Gruber, Diane (Committee member) / School of Humanities, Arts, and Cultural Studies (Contributor) / School of Social and Behavioral Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2015-12
Description
Vitamin D, a bioactive lipid and essential nutrient, is obtained by humans through either endogenous synthesis in response to UV light exposure or via nutritional intake. Once activated to its hormonal form, vitamin D binds to and activates the nuclear vitamin D receptor (VDR). Activation of VDR is known to modulate gene transcription in vitamin D target tissues such as kidney, colon, and bone; however, less is known about the ability of VDR to respond to "nutritional modulators". One such potential VDR modulator is resveratrol, a plant-derived polyphenol and potent antioxidant nutrient that also functions as a chemopreventative. Resveratrol is known to activate sirtuin-1, a deacetylase enzyme with potential anti-aging properties. This study explores the potential for resveratrol, an anticancer nutraceutical, to upregulate VDR activity through its effector protein, sirtuin-1. Furthermore, due to its putative interactions with several intracellular signaling pathways, klotho has been proposed as an anti-aging protein and tumor suppressor gene, while the Wnt/β-catenin signaling pathway drives enhanced cellular proliferation leading to numerous types of cancers, especially colorectal neoplasia. Thus, the ability of klotho to cooperate with vitamin D to inhibit oncogenic β-catenin signaling was also analyzed. The experiments and resultant data presented in this thesis explore the potential role of VDR as a physiologically relevant nutritional sensor in human cells. This novel study reveals the importance of nutrient modulation of the VDR system by vitamin D and resveratrol and how this might represent a molecular mechanism that is responsible for the putative anti-cancer actions of vitamin D. Furthermore, this study enhances our understanding of how vitamin D/VDR and resveratrol interact with klotho and how this interaction affects β-catenin signaling to mitigate oncogenic growth and differentiation. This works demonstrates that the vitamin D hormone serves as a likely chemopreventive agent for various types of cancers through control of anti-oxidation and cellular proliferation pathways via its nuclear receptor. Our results also indicate the potential for resveratrol, an anticancer nutraceutical, to upregulate VDR activity through SIRT1. Furthermore, the novel data presented in this work illustrate that klotho, an anti-aging protein, cooperates with vitamin D to synergistically inhibit oncogenic β-catenin signaling. Ultimately, this study enhances our understating of the molecular pathways that underpin nutritional chemoprevention, and how modulation of these pathways via dietary intervention may lead to advances in public health strategies to eventually curb carcinogenesis.
ContributorsKhan, Zainab (Author) / Jurutka, Peter (Thesis director) / Hackney Price, Jennifer (Committee member) / School of Mathematical and Natural Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05