The burden of dementia and its primary cause, Alzheimer’s disease, continue to devastate many with no available cure although present research has delivered methods for risk calculation and models of disease development that promote preventative strategies. Presently Alzheimer’s disease affects 1 in 9 people aged 65 and older amounting to a total annual healthcare cost in 2023 in the United States of $345 billion between Alzheimer’s disease and other dementias making dementia one of the costliest conditions to society (“2023 Alzheimer’s Disease Facts and Figures,” 2023). This substantial cost can be dramatically lowered in addition to a reduction in the overall burden of dementia through the help of risk prediction models, but there is still a need for models to deliver an individual’s predicted time of onset that supplements risk prediction in hopes of improving preventative care. The aim of this study is to develop a model used to predict the age of onset for all-cause dementias and Alzheimer’s disease using demographic, comorbidity, and genetic data from a cohort sample. This study creates multiple regression models with methods of ordinary least squares (OLS) and least absolute shrinkage and selection operator (LASSO) regression methods to understand the capacity of predictor variables that estimate age of onset for all-cause dementia and Alzheimer’s disease. This study is unique in its use of a diverse cohort containing 346 participants to create a predictive model that originates from the All of Us Research Program database and seeks to represent an accurate sampling of the United States population. The regression models generated had no predictive capacity for the age of onset but outline a simplified approach for integrating public health data into a predictive model. The results from the generated models suggest a need for continued research linking risk factors that estimate time of onset.

Studio 31 is a startup venture founded by Brandon Goldberg, Ryan Johnston, Samuel Vogel, and Ekaterina Korneva. The company offers affordable art prints created by aspiring artists through an online platform. Our mission is to connect these artists with art lovers and provide them with the tools to build sustainable careers. Key activities of Studio 31 include curating a set of artworks, maintaining a print-on-demand system for sustainable production, and penetration of the target market through strong digital media positioning. The field of art is replete with talented artists who are just starting their professional careers and are not represented in the art market. The works of art of such artists are unknown and inaccessible to the target audience, which complicates the process of their professional development and limits the variety of artworks available on the market. Studio 31 infiltrates the art community and forms partnerships with talented artists to then provide the target market with access to exclusive artwork through an established sales and production process. The advantages of an established business process are no risk to the artist, cost-efficient production that correlates with demand, and a predictable cash flow from operations. The current state of the industry and trends affecting the target market confirm the viability of Studio 31's business model. The covid-19 crisis has affected the art market, shifting focus to online sales. Moreover, due to people spending more time at home, the demand for art products has increased. Our team is uniquely positioned to bring the Studio 31 business plan to life. With Katrin, Ryan, Brandon, and Samuel as the management team, the project is supported by expertise in entrepreneurship, management and policy, economics, marketing and design Implementation and marketing are the key activities of the company on the way to gaining traction in the target market. Studio 31 will develop multiple direct and indirect distribution channels to provide customers with diversified access to offerings. The website will serve as the main direct channel to connect with buyers, displaying the full list of offers available for order. In addition, the company will be present on numerous social media platforms in order to notify the target audience of current offers in a timely manner. Both the website and social media accounts will grow through paid advertising and influencer marketing. The project's initial funding consists of Barrett, the Honors College Thesis Funding. These resources covered the overhead costs required to get started, such as the website and initial product prototypes. The seed funding will also be used for market research and business process testing to improve the company's performance and subsequently maximize profits. The team will resort to a crowdfunding strategy if additional funding resources are needed to cover the initial costs. The project will be presented to the public to receive financial assistance for business development. The investment will be encouraged by incentives such as discounts on future sales.

Studio 31 is a startup venture founded by Brandon Goldberg, Ryan Johnston, Samuel Vogel, and Ekaterina Korneva. The company offers affordable art prints created by aspiring artists through an online platform. Our mission is to connect these artists with art lovers and provide them with the tools to build sustainable careers. Key activities of Studio 31 include curating a set of artworks, maintaining a print-on-demand system for sustainable production, and penetration of the target market through strong digital media positioning. The field of art is replete with talented artists who are just starting their professional careers and are not represented in the art market. The works of art of such artists are unknown and inaccessible to the target audience, which complicates the process of their professional development and limits the variety of artworks available on the market. Studio 31 infiltrates the art community and forms partnerships with talented artists to then provide the target market with access to exclusive artwork through an established sales and production process. The advantages of an established business process are no risk to the artist, cost-efficient production that correlates with demand, and a predictable cash flow from operations. The current state of the industry and trends affecting the target market confirm the viability of Studio 31's business model. The covid-19 crisis has affected the art market, shifting focus to online sales. Moreover, due to people spending more time at home, the demand for art products has increased. Our team is uniquely positioned to bring the Studio 31 business plan to life. With Katrin, Ryan, Brandon, and Samuel as the management team, the project is supported by expertise in entrepreneurship, management and policy, economics, marketing and design Implementation and marketing are the key activities of the company on the way to gaining traction in the target market. Studio 31 will develop multiple direct and indirect distribution channels to provide customers with diversified access to offerings. The website will serve as the main direct channel to connect with buyers, displaying the full list of offers available for order. In addition, the company will be present on numerous social media platforms in order to notify the target audience of current offers in a timely manner. Both the website and social media accounts will grow through paid advertising and influencer marketing. The project's initial funding consists of Barrett, the Honors College Thesis Funding. These resources covered the overhead costs required to get started, such as the website and initial product prototypes. The seed funding will also be used for market research and business process testing to improve the company's performance and subsequently maximize profits. The team will resort to a crowdfunding strategy if additional funding resources are needed to cover the initial costs. The project will be presented to the public to receive financial assistance for business development. The investment will be encouraged by incentives such as discounts on future sales.

Director Wes Anderson enlisted the talents of composer Mark Mothersbaugh for his first four films (1996-2004), but suddenly decided to turn to composer Alexandre Desplat for the following five films (2009-2021). The question arises as to why this would be the case. In this paper I explore the career backgrounds of Mothersbaugh and Desplat including their musical influences and styles. I then examine Mothersbaugh’s music for The Life Aquatic with Steve Zissou and Desplat’s score for The French Dispatch. I analyze the use of music in these films and how it relates to the characters, their feelings, and their thoughts as well as how the music is intertwined with Anderson’s unique direction style. Part of this investigation will highlight the musical styles used, the mixture between composed and borrowed music, and the function of the music in the film to discover the similarities and differences between the two composers. With this paper I hope to fill a gap in the literature on film studies focused on the work of Anderson.

With an increase in Artificial Intelligence applications in the world of technology, its usage has extended as far as the world of business, with small, medium, and large firms offering both products and services for consumer and business use. Through its historical development, and the devolvement of frameworks, algorithms, and basic toolkits, the application of AI in business was able to flourish. The development of multiple tools such as smart stethoscopes and conversational assistants throughout multiple industries has created a complex commercial enterprise of Artificial Intelligence for the specific genre of business and its applications today are bound to have major effects on the AI applications of tomorrow.