Matching Items (1,594)
Filtering by
- Creators: School of Life Sciences
Description
Urbanization and infrastructure development often brings dramatic changes in the surface and groundwater regimes. These changes in moisture content may be particularly problematic when subsurface soils are moisture sensitive such as expansive soils. Residential foundations such as slab-on ground may be built on unsaturated expansive soils and therefore have to resist the deformations associated with change in moisture content (matric suction) in the soil. The problem is more pronounced in arid and semi arid regions with drying periods followed by wet season resulting in large changes in soil suction. Moisture content change causes volume change in expansive soil which causes serious damage to the structures. In order to mitigate these ill effects various mitigation are adopted. The most commonly adopted method in the US is the removal and replacement of upper soils in the profile. The remove and replace method, although heavily used, is not well understood with regard to its impact on the depth of soil wetting or near-surface differential soil movements. In this study the effectiveness of the remove and replace method is studied. A parametric study is done with various removal and replacement materials used and analyzed to obtain the optimal replacement depths and best material. The depth of wetting and heave caused in expansive soil profile under climatic conditions and common irrigation scenarios are studied for arid regions. Soil suction changes and associated soil deformations are analyzed using finite element codes for unsaturated flow and stress/deformation, SVFlux and SVSolid, respectively. The effectiveness and fundamental mechanisms at play in mitigation of expansive soils for remove and replace methods are studied, and include (1) its role in reducing the depth and degree of wetting, and (2) its effect in reducing the overall heave potential, and (3) the effectiveness of this method in pushing the seat of movement deeper within the soil profile to reduce differential soil surface movements. Various non-expansive replacement layers and different surface flux boundary conditions are analyzed, and the concept of optimal depth and soil is introduced. General observations are made concerning the efficacy of remove and replace as a mitigation method.
ContributorsBharadwaj, Anushree (Author) / Houston, Sandra L. (Thesis advisor) / Welfert, Bruno (Thesis advisor) / Zapata, Claudia E (Committee member) / Arizona State University (Publisher)
Created2013
Description
Obtaining high-quality experimental designs to optimize statistical efficiency and data quality is quite challenging for functional magnetic resonance imaging (fMRI). The primary fMRI design issue is on the selection of the best sequence of stimuli based on a statistically meaningful optimality criterion. Some previous studies have provided some guidance and powerful computational tools for obtaining good fMRI designs. However, these results are mainly for basic experimental settings with simple statistical models. In this work, a type of modern fMRI experiments is considered, in which the design matrix of the statistical model depends not only on the selected design, but also on the experimental subject's probabilistic behavior during the experiment. The design matrix is thus uncertain at the design stage, making it diffcult to select good designs. By taking this uncertainty into account, a very efficient approach for obtaining high-quality fMRI designs is developed in this study. The proposed approach is built upon an analytical result, and an efficient computer algorithm. It is shown through case studies that the proposed approach can outperform an existing method in terms of computing time, and the quality of the obtained designs.
ContributorsZhou, Lin (Author) / Kao, Ming-Hung (Thesis advisor) / Reiser, Mark R. (Committee member) / Stufken, John (Committee member) / Welfert, Bruno (Committee member) / Arizona State University (Publisher)
Created2014
Description
In many classication problems data samples cannot be collected easily, example in drug trials, biological experiments and study on cancer patients. In many situations the data set size is small and there are many outliers. When classifying such data, example cancer vs normal patients the consequences of mis-classication are probably more important than any other data type, because the data point could be a cancer patient or the classication decision could help determine what gene might be over expressed and perhaps a cause of cancer. These mis-classications are typically higher in the presence of outlier data points. The aim of this thesis is to develop a maximum margin classier that is suited to address the lack of robustness of discriminant based classiers (like the Support Vector Machine (SVM)) to noise and outliers. The underlying notion is to adopt and develop a natural loss function that is more robust to outliers and more representative of the true loss function of the data. It is demonstrated experimentally that SVM's are indeed susceptible to outliers and that the new classier developed, here coined as Robust-SVM (RSVM), is superior to all studied classier on the synthetic datasets. It is superior to the SVM in both the synthetic and experimental data from biomedical studies and is competent to a classier derived on similar lines when real life data examples are considered.
ContributorsGupta, Sidharth (Author) / Kim, Seungchan (Thesis advisor) / Welfert, Bruno (Committee member) / Li, Baoxin (Committee member) / Arizona State University (Publisher)
Created2011
Description
The Kuramoto model is an archetypal model for studying synchronization in groups
of nonidentical oscillators where oscillators are imbued with their own frequency and
coupled with other oscillators though a network of interactions. As the coupling
strength increases, there is a bifurcation to complete synchronization where all oscillators
move with the same frequency and show a collective rhythm. Kuramoto-like
dynamics are considered a relevant model for instabilities of the AC-power grid which
operates in synchrony under standard conditions but exhibits, in a state of failure,
segmentation of the grid into desynchronized clusters.
In this dissertation the minimum coupling strength required to ensure total frequency
synchronization in a Kuramoto system, called the critical coupling, is investigated.
For coupling strength below the critical coupling, clusters of oscillators form
where oscillators within a cluster are on average oscillating with the same long-term
frequency. A unified order parameter based approach is developed to create approximations
of the critical coupling. Some of the new approximations provide strict lower
bounds for the critical coupling. In addition, these approximations allow for predictions
of the partially synchronized clusters that emerge in the bifurcation from the
synchronized state.
Merging the order parameter approach with graph theoretical concepts leads to a
characterization of this bifurcation as a weighted graph partitioning problem on an
arbitrary networks which then leads to an optimization problem that can efficiently
estimate the partially synchronized clusters. Numerical experiments on random Kuramoto
systems show the high accuracy of these methods. An interpretation of the
methods in the context of power systems is provided.
of nonidentical oscillators where oscillators are imbued with their own frequency and
coupled with other oscillators though a network of interactions. As the coupling
strength increases, there is a bifurcation to complete synchronization where all oscillators
move with the same frequency and show a collective rhythm. Kuramoto-like
dynamics are considered a relevant model for instabilities of the AC-power grid which
operates in synchrony under standard conditions but exhibits, in a state of failure,
segmentation of the grid into desynchronized clusters.
In this dissertation the minimum coupling strength required to ensure total frequency
synchronization in a Kuramoto system, called the critical coupling, is investigated.
For coupling strength below the critical coupling, clusters of oscillators form
where oscillators within a cluster are on average oscillating with the same long-term
frequency. A unified order parameter based approach is developed to create approximations
of the critical coupling. Some of the new approximations provide strict lower
bounds for the critical coupling. In addition, these approximations allow for predictions
of the partially synchronized clusters that emerge in the bifurcation from the
synchronized state.
Merging the order parameter approach with graph theoretical concepts leads to a
characterization of this bifurcation as a weighted graph partitioning problem on an
arbitrary networks which then leads to an optimization problem that can efficiently
estimate the partially synchronized clusters. Numerical experiments on random Kuramoto
systems show the high accuracy of these methods. An interpretation of the
methods in the context of power systems is provided.
ContributorsGilg, Brady (Author) / Armbruster, Dieter (Thesis advisor) / Mittelmann, Hans (Committee member) / Scaglione, Anna (Committee member) / Strogatz, Steven (Committee member) / Welfert, Bruno (Committee member) / Arizona State University (Publisher)
Created2018
Description
The dynamics of a fluid flow inside 2D square and 3D cubic cavities
under various configurations were simulated and analyzed using a
spectral code I developed.
This code was validated against known studies in the 3D lid-driven
cavity. It was then used to explore the various dynamical behaviors
close to the onset of instability of the steady-state flow, and explain
in the process the mechanism underlying an intermittent bursting
previously observed. A fairly complete bifurcation picture emerged,
using a combination of computational tools such as selective
frequency damping, edge-state tracking and subspace restriction.
The code was then used to investigate the flow in a 2D square cavity
under stable temperature stratification, an idealized version of a lake
with warmer water at the surface compared to the bottom. The governing
equations are the Navier-Stokes equations under the Boussinesq approximation.
Simulations were done over a wide range of parameters of the problem quantifying
the driving velocity at the top (e.g. wind) and the strength of the stratification.
Particular attention was paid to the mechanisms associated with the onset of
instability of the base steady state, and the complex nontrivial dynamics
occurring beyond onset, where the presence of multiple states leads to a
rich spectrum of states, including homoclinic and heteroclinic chaos.
A third configuration investigates the flow dynamics of a fluid in a rapidly
rotating cube subjected to small amplitude modulations. The responses were
quantified by the global helicity and energy measures, and various peak
responses associated to resonances with intrinsic eigenmodes of the cavity
and/or internal retracing beams were clearly identified for the first time.
A novel approach to compute the eigenmodes is also described, making accessible
a whole catalog of these with various properties and dynamics. When the small
amplitude modulation does not align with the rotation axis (precession) we show
that a new set of eigenmodes are primarily excited as the angular velocity
increases, while triadic resonances may occur once the nonlinear regime kicks in.
under various configurations were simulated and analyzed using a
spectral code I developed.
This code was validated against known studies in the 3D lid-driven
cavity. It was then used to explore the various dynamical behaviors
close to the onset of instability of the steady-state flow, and explain
in the process the mechanism underlying an intermittent bursting
previously observed. A fairly complete bifurcation picture emerged,
using a combination of computational tools such as selective
frequency damping, edge-state tracking and subspace restriction.
The code was then used to investigate the flow in a 2D square cavity
under stable temperature stratification, an idealized version of a lake
with warmer water at the surface compared to the bottom. The governing
equations are the Navier-Stokes equations under the Boussinesq approximation.
Simulations were done over a wide range of parameters of the problem quantifying
the driving velocity at the top (e.g. wind) and the strength of the stratification.
Particular attention was paid to the mechanisms associated with the onset of
instability of the base steady state, and the complex nontrivial dynamics
occurring beyond onset, where the presence of multiple states leads to a
rich spectrum of states, including homoclinic and heteroclinic chaos.
A third configuration investigates the flow dynamics of a fluid in a rapidly
rotating cube subjected to small amplitude modulations. The responses were
quantified by the global helicity and energy measures, and various peak
responses associated to resonances with intrinsic eigenmodes of the cavity
and/or internal retracing beams were clearly identified for the first time.
A novel approach to compute the eigenmodes is also described, making accessible
a whole catalog of these with various properties and dynamics. When the small
amplitude modulation does not align with the rotation axis (precession) we show
that a new set of eigenmodes are primarily excited as the angular velocity
increases, while triadic resonances may occur once the nonlinear regime kicks in.
ContributorsWu, Ke (Author) / Lopez, Juan (Thesis advisor) / Welfert, Bruno (Thesis advisor) / Tang, Wenbo (Committee member) / Platte, Rodrigo (Committee member) / Herrmann, Marcus (Committee member) / Arizona State University (Publisher)
Created2019
Description
The inherent risk in testing drugs has been hotly debated since the government first started regulating the drug industry in the early 1900s. Who can assume the risks associated with trying new pharmaceuticals is unclear when looked at through society's lens. In the mid twentieth century, the US Food and Drug Administration (FDA) published several guidance documents encouraging researchers to exclude women from early clinical drug research. The motivation to publish those documents and the subsequent guidance documents in which the FDA and other regulatory offices established their standpoints on women in drug research may have been connected to current events at the time. The problem of whether women should be involved in drug research is a question of who can assume risk and who is responsible for disseminating what specific kinds of information. The problem tends to be framed as one that juxtaposes the health of women and fetuses and sets their health as in opposition. That opposition, coupled with the inherent uncertainty in testing drugs, provides for a complex set of issues surrounding consent and access to information.
ContributorsMeek, Caroline Jane (Author) / Maienschein, Jane (Thesis director) / Brian, Jennifer (Committee member) / School of Life Sciences (Contributor) / Sanford School of Social and Family Dynamics (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
Social-emotional learning (SEL) methods are beginning to receive global attention in primary school education, yet the dominant emphasis on implementing these curricula is in high-income, urbanized areas. Consequently, the unique features of developing and integrating such methods in middle- or low-income rural areas are unclear. Past studies suggest that students exposed to SEL programs show an increase in academic performance, improved ability to cope with stress, and better attitudes about themselves, others, and school, but these curricula are designed with an urban focus. The purpose of this study was to conduct a needs-based analysis to investigate components specific to a SEL curriculum contextualized to rural primary schools. A promising organization committed to rural educational development is Barefoot College, located in Tilonia, Rajasthan, India. In partnership with Barefoot, we designed an ethnographic study to identify and describe what teachers and school leaders consider the highest needs related to their students' social and emotional education. To do so, we interviewed 14 teachers and school leaders individually or in a focus group to explore their present understanding of “social-emotional learning” and the perception of their students’ social and emotional intelligence. Analysis of this data uncovered common themes among classroom behaviors and prevalent opportunities to address social and emotional well-being among students. These themes translated into the three overarching topics and eight sub-topics explored throughout the curriculum, and these opportunities guided the creation of the 21 modules within it. Through a design-based research methodology, we developed a 40-hour curriculum by implementing its various modules within seven Barefoot classrooms alongside continuous reiteration based on teacher feedback and participant observation. Through this process, we found that student engagement increased during contextualized SEL lessons as opposed to traditional methods. In addition, we found that teachers and students preferred and performed better with an activities-based approach. These findings suggest that rural educators must employ particular teaching strategies when addressing SEL, including localized content and an experiential-learning approach. Teachers reported that as their approach to SEL shifted, they began to unlock the potential to build self-aware, globally-minded students. This study concludes that social and emotional education cannot be treated in a generalized manner, as curriculum development is central to the teaching-learning process.
ContributorsBucker, Delaney Sue (Author) / Carrese, Susan (Thesis director) / Barab, Sasha (Committee member) / School of Life Sciences (Contributor, Contributor) / School of Civic & Economic Thought and Leadership (Contributor) / School of International Letters and Cultures (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
As of 2019, 30 US states have adopted abortion-specific informed consent laws that require state health departments to develop and disseminate written informational materials to patients seeking an abortion. Abortion is the only medical procedure for which states dictate the content of informed consent counseling. State abortion counseling materials have been criticized for containing inaccurate and misleading information, but overall, informed consent laws for abortion do not often receive national attention. The objective of this project was to determine the importance of informed consent laws to achieving the larger goal of dismantling the right to abortion. I found that informed consent counseling materials in most states contain a full timeline of fetal development, along with information about the risks of abortion, the risks of childbirth, and alternatives to abortion. In addition, informed consent laws for abortion are based on model legislation called the “Women’s Right to Know Act” developed by Americans United for Life (AUL). AUL calls itself the legal architect of the pro-life movement and works to pass laws at the state level that incrementally restrict abortion access so that it gradually becomes more difficult to exercise the right to abortion established by Roe v. Wade. The “Women’s Right to Know Act” is part of a larger package of model legislation called the “Women’s Protection Project,” a cluster of laws that place restrictions on abortion providers, purportedly to protect women, but actually to decrease abortion access. “Women’s Right to Know” counseling laws do not directly deny access to abortion, but they do reinforce key ideas important to the anti-abortion movement, like the concept of fetal personhood, distrust in medical professionals, the belief that pregnant people cannot be fully autonomous individuals, and the belief that abortion is not an ordinary medical procedure and requires special government oversight. “Women’s Right to Know” laws use the language of informed consent and the purported goal of protecting women to legitimize those ideas, and in doing so, they significantly undermine the right to abortion. The threat to abortion rights posed by laws like the “Women’s Right to Know” laws indicates the need to reevaluate and strengthen our ethical defense of the right to abortion.
ContributorsVenkatraman, Richa (Author) / Maienschein, Jane (Thesis director) / Brian, Jennifer (Thesis director) / Abboud, Carolina (Committee member) / Historical, Philosophical & Religious Studies (Contributor) / School of Life Sciences (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
Turbidity is a known problem for UV water treatment systems as suspended particles can shield contaminants from the UV radiation. UV systems that utilize a reflective radiation chamber may be able to decrease the impact of turbidity on the efficacy of the system. The purpose of this study was to determine how kaolin clay and gram flour turbidity affects inactivation of Escherichia coli (E. coli) when using a UV system with a reflective chamber. Both sources of turbidity were shown to reduce the inactivation of E. coli with increasing concentrations. Overall, it was shown that increasing kaolin clay turbidity had a consistent effect on reducing UV inactivation across UV doses. Log inactivation was reduced by 1.48 log for the low UV dose and it was reduced by at least 1.31 log for the low UV dose. Gram flour had a similar effect to the clay at the lower UV dose, reducing log inactivation by 1.58 log. At the high UV dose, there was no change in UV inactivation with an increase in turbidity. In conclusion, turbidity has a significant impact on the efficacy of UV disinfection. Therefore, removing turbidity from water is an essential process to enhance UV efficiency for the disinfection of microbial pathogens.
ContributorsMalladi, Rohith (Author) / Abbaszadegan, Morteza (Thesis director) / Alum, Absar (Committee member) / Fox, Peter (Committee member) / School of Human Evolution & Social Change (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
Aquatic macroinvertebrates are important for many ecological processes within river ecosystems and, as a result, their abundance and diversity are considered indicators of water quality and ecosystem health. Macroinvertebrates can be classified into functional feeding groups (FFG) based on morphological-behavioral adaptations. FFG ratios can shift due to changes in normal disturbance patterns, such as changes in precipitation, and from human impact. Due to their increased sensitivity to environmental changes, it has become more important to protect and monitor aquatic and riparian communities in arid regions as climate change continues to intensify. Therefore, the diversity and richness of macroinvertebrate FFGs before and after monsoon and winter storm seasons were analyzed to determine the effect of flow-related disturbances. Ecosystem size was also considered, as watershed area has been shown to affect macroinvertebrate diversity. There was no strong support for flow-related disturbance or ecosystem size on macroinvertebrate diversity and richness. This may indicate a need to explore other parameters of macroinvertebrate community assembly. Establishing how disturbance affects aquatic macroinvertebrate communities will provide a key understanding as to what the stream communities will look like in the future, as anthropogenic impacts continue to affect more vulnerable ecosystems.
ContributorsSainz, Ruby (Author) / Sabo, John (Thesis director) / Grimm, Nancy (Committee member) / Lupoli, Christina (Committee member) / School of Life Sciences (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2020-05