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Description
The interaction between visual fixations during planning and performance in a

dexterous task was analyzed. An eye-tracking device was affixed to subjects during

sequences of null (salient center of mass) and weighted (non salient center of mass) trials

with unconstrained precision grasp. Subjects experienced both expected and unexpected

perturbations, with the task of minimizing

The interaction between visual fixations during planning and performance in a

dexterous task was analyzed. An eye-tracking device was affixed to subjects during

sequences of null (salient center of mass) and weighted (non salient center of mass) trials

with unconstrained precision grasp. Subjects experienced both expected and unexpected

perturbations, with the task of minimizing object roll. Unexpected perturbations were

controlled by switching weights between trials, expected perturbations were controlled by

asking subjects to rotate the object themselves. In all cases subjects were able to

minimize the roll of the object within three trials. Eye fixations were correlated with

object weight for the initial context and for known shifts in center of mass. In subsequent

trials with unexpected weight shifts, subjects appeared to scan areas of interest from both

contexts even after learning present orientation.
ContributorsSmith, Michael David (Author) / Santello, Marco (Thesis advisor) / Buneo, Christopher (Committee member) / Schaefer, Sydney (Committee member) / Arizona State University (Publisher)
Created2017
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Description
The human hand is a complex biological system. Humans have evolved a unique ability to use the hand for a wide range of tasks, including activities of daily living such as successfully grasping and manipulating objects, i.e., lifting a cup of coffee without spilling. Despite the ubiquitous nature of hand

The human hand is a complex biological system. Humans have evolved a unique ability to use the hand for a wide range of tasks, including activities of daily living such as successfully grasping and manipulating objects, i.e., lifting a cup of coffee without spilling. Despite the ubiquitous nature of hand use in everyday activities involving object manipulations, there is currently an incomplete understanding of the cortical sensorimotor mechanisms underlying this important behavior. One critical aspect of natural object grasping is the coordination of where the fingers make contact with an object and how much force is applied following contact. Such force-to-position modulation is critical for successful manipulation. However, the neural mechanisms underlying these motor processes remain less understood, as previous experiments have utilized protocols with fixed contact points which likely rely on different neural mechanisms from those involved in grasping at unconstrained contacts. To address this gap in the motor neuroscience field, transcranial magnetic stimulation (TMS) and electroencephalography (EEG) were used to investigate the role of primary motor cortex (M1), as well as other important cortical regions in the grasping network, during the planning and execution of object grasping and manipulation. The results of virtual lesions induced by TMS and EEG revealed grasp context-specific cortical mechanisms underlying digit force-to-position coordination, as well as the spatial and temporal dynamics of cortical activity during planning and execution. Together, the present findings provide the foundation for a novel framework accounting for how the central nervous system controls dexterous manipulation. This new knowledge can potentially benefit research in neuroprosthetics and improve the efficacy of neurorehabilitation techniques for patients affected by sensorimotor impairments.
ContributorsMcGurrin, Patrick M (Author) / Santello, Marco (Thesis advisor) / Helms-Tillery, Steve (Committee member) / Kleim, Jeff (Committee member) / Davare, Marco (Committee member) / Arizona State University (Publisher)
Created2017
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Description

The human hand has so many degrees of freedom that it may seem impossible to control. A potential solution to this problem is “synergy control” which combines dimensionality reduction with great flexibility. With applicability to a wide range of tasks, this has become a very popular concept. In this review,

The human hand has so many degrees of freedom that it may seem impossible to control. A potential solution to this problem is “synergy control” which combines dimensionality reduction with great flexibility. With applicability to a wide range of tasks, this has become a very popular concept. In this review, we describe the evolution of the modern concept using studies of kinematic and force synergies in human hand control, neurophysiology of cortical and spinal neurons, and electromyographic (EMG) activity of hand muscles. We go beyond the often purely descriptive usage of synergy by reviewing the organization of the underlying neuronal circuitry in order to propose mechanistic explanations for various observed synergy phenomena. Finally, we propose a theoretical framework to reconcile important and still debated concepts such as the definitions of “fixed” vs. “flexible” synergies and mechanisms underlying the combination of synergies for hand control.

ContributorsSantello, Marco (Author) / Baud-Bovy, Gabriel (Author) / Jorntell, Henrik (Author) / Ira A. Fulton Schools of Engineering (Contributor)
Created2013-04-08
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Description

Exposure to fine particles can cause various diseases, and an easily accessible method to monitor the particles can help raise public awareness and reduce harmful exposures. Here we report a method to estimate PM air pollution based on analysis of a large number of outdoor images available for Beijing, Shanghai

Exposure to fine particles can cause various diseases, and an easily accessible method to monitor the particles can help raise public awareness and reduce harmful exposures. Here we report a method to estimate PM air pollution based on analysis of a large number of outdoor images available for Beijing, Shanghai (China) and Phoenix (US). Six image features were extracted from the images, which were used, together with other relevant data, such as the position of the sun, date, time, geographic information and weather conditions, to predict PM2.5 index. The results demonstrate that the image analysis method provides good prediction of PM2.5 indexes, and different features have different significance levels in the prediction.

ContributorsLiu, Chenbin (Author) / Tsow, Francis (Author) / Zou, Yi (Author) / Tao, Nongjian (Author) / Biodesign Institute (Contributor)
Created2016-02-01
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Description

Pure coconut oil, lanolin, and acetaminophen were vaporized at rates of 1–50 mg/min, using a porous network exhibiting a temperature gradient from 5000 to 5500 K/mm, without incurring noticeable chemical changes due to combustion, oxidation, or other thermally-induced chemical structural changes. The newly coined term “ereptiospiration” is used here to

Pure coconut oil, lanolin, and acetaminophen were vaporized at rates of 1–50 mg/min, using a porous network exhibiting a temperature gradient from 5000 to 5500 K/mm, without incurring noticeable chemical changes due to combustion, oxidation, or other thermally-induced chemical structural changes. The newly coined term “ereptiospiration” is used here to describe this combination of thermal transpiration at high temperature gradients since the process can force the creation of thermal aerosols by rapid heating in a localized zone. Experimental data were generated for these materials using two different supports for metering the materials to the battery powered coil: namely, a stainless steel fiber bundle and a 3-D printed steel cartridge. Heating coconut oil, lanolin, or acetaminophen in a beaker to lower temperatures than those achieved at the surface of the coil showed noticeable and rapid degradation in the samples, while visual and olfactory observations for ereptiospiration showed no noticeable degradation in lanolin and coconut oil while HPLC chromatograms along with visual observation confirm that within the limit of detection, acetaminophen remains chemically unaltered by ereptiospiration.

ContributorsWoolley, Christine (Author) / Garcia, Antonio (Author) / Santello, Marco (Author) / Ira A. Fulton Schools of Engineering (Contributor)
Created2017-04-12
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Description

A novel portable wireless volatile organic compound (VOC) monitoring device with disposable sensors is presented. The device is miniaturized, light, easy-to-use, and cost-effective. Different field tests have been carried out to identify the operational, analytical, and functional performance of the device and its sensors. The device was compared to a

A novel portable wireless volatile organic compound (VOC) monitoring device with disposable sensors is presented. The device is miniaturized, light, easy-to-use, and cost-effective. Different field tests have been carried out to identify the operational, analytical, and functional performance of the device and its sensors. The device was compared to a commercial photo-ionization detector, gas chromatography-mass spectrometry, and carbon monoxide detector. In addition, environmental operational conditions, such as barometric change, temperature change and wind conditions were also tested to evaluate the device performance. The multiple comparisons and tests indicate that the proposed VOC device is adequate to characterize personal exposure in many real-world scenarios and is applicable for personal daily use.

ContributorsDeng, Yue (Author) / Chen, Cheng (Author) / Xian, Xiaojun (Author) / Tsow, Francis (Author) / Verma, Gaurav (Author) / McConnell, Rob (Author) / Fruin, Scott (Author) / Tao, Nongjian (Author) / Forzani, Erica (Author) / Ira A. Fulton Schools of Engineering (Contributor)
Created2016-12-03