Matching Items (314)
Description
As technology becomes more available to the public, cybercriminals are able to utilize these tools to circumvent outdated modes of protection and steal this information. My aim with my thesis is to understand the effects of cyberterror and cybercrime on the United States and the world and help spread awareness to the public and encourage proactivity in taking the proper steps to protect your information and stop those who would try and take it.
ContributorsLeung, Kevin (Author) / Fehler, Michelle (Thesis director) / Heywood, William (Committee member) / Barrett, The Honors College (Contributor) / School of Historical, Philosophical and Religious Studies (Contributor) / The Design School (Contributor)
Created2015-05
Description
In my Honors Thesis, I endeavor to complicate and to respond to conventional debates over historical periodization and the problem of what it means to be "modern." I understand the modern as a conceptual product of discourses surrounding religion, science, and industry. Specifically, the modern era has been defined as one in which the forms of rationalization associated with quantitative and experimental scientific methods and large-scale, technologically sophisticated industrial production have surpassed the "irrational" superstitions associated with religion. Critical responses to this definition have largely had the goal of supplanting it with another way of conceiving of the historical discontinuity between the "modern" and the "non-modern." In three essays, I aim to complicate the terms (religion, science, and industry) in which these debates have been conducted and to relate them to one another both historically and conceptually. As opposed to the goal of re-defining the modern, my goal in these essays is to complicate the existing definitions and to reveal and challenge the ideological motives of historical periodization. I illuminate the connections of the modern conception of "religion" to a colonial system of power, between scientific development and changes in economic and religious thinking, and between contemporary technological and industrial projects to an "enchanted" view of the world. In tracing these connections, I am indebted to conventional discourses of modernization, Max Weber's theory of "disenchantment," and recent scholarship on the use of materialist methods in the study of history. In these essays, I move beyond the critical project of "re-imagining" the modern, and illuminate some of the ideological commitments of that project that I consider untenable. In addition to a more sophisticated historical understanding of the meaning of religion, science, and industry, what I aim to achieve in my thesis is a better framing of some of the largest problems faced by contemporary humanity, including the looming risks of ecological, economic, and geopolitical collapse. In this framing, I situate these risks in the context of their connection to strategies of historical periodization, and argue that managing them will require a radically new view of religion, science, industry, and the roles that they play in producing historical discontinuity.
ContributorsNeibergall, William (Author) / Bennett, Gaymon (Thesis director) / Suk, Mina (Committee member) / School of Historical, Philosophical and Religious Studies (Contributor) / Department of English (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
Analysis into the political career of Texas state senator George Ruby provides invaluable insight to the African American experience during Reconstruction in Texas as a whole. Juxtaposing the needs vocalized by African American communities and the actions taken by Ruby, the Freedmen’s Bureau, and other Texas politicians, helps identify how racial politics dictated the lives of Texas African Americans. Ruby’s rise to power can also be utilized as a historical blueprint for how leaders in marginalized communities can become impactful and obtain power within a racially-biased societal structure. Ruby’s rise and fall in Texas politics is tragic as he finds himself forced to separate from his loyal African American support base—deciding to cater to the needs of elite white Texans to help ensure political favor on both sides of the political and racial spectrum. However, Ruby’s legacy remains one of great success as he managed to break the mold forced upon so many African Americans during Reconstruction and enact lasting change in the marginalized Texas African American communities.
ContributorsCourson, Shawn Thomas (Author) / Schermerhorn, J. (Thesis director) / Delmont, Matthew (Committee member) / School of Politics and Global Studies (Contributor) / School of Historical, Philosophical and Religious Studies (Contributor) / Division of Teacher Preparation (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
The human hairless gene (HR) encodes a 130 kDa transcription factor that is primarily expressed in the brain and skin. In the promoter and 5'-untranslated regions (5'-UTR) of HR, there are three putative consensus p53 responsive elements (p53RE). p53 is a tumor suppressor protein that regulates cell proliferation, apoptosis, and other cell functions. The p53 protein, a known tumor suppressor, acts as a transcription factor and binds to DNA p53REs to activate or repress transcription of the target gene. In general, the p53 binding sequence is 5'-RRRCWWGYYY-3' where W is A or T, and R and Y are purines or pyrimidines, respectively. However, even if the p53 binding sequence does not match the consensus sequence, p53 protein might still be able to bind to the response element. The intent of this investigation was to identify and characterize the p53REs in the promoter and 5'-UTR of HR. If the three p53REs (p53RE1, p53RE2, and p53RE3) are functional, then p53 can bind there and might regulate HR gene expression. The first aim for this thesis was to clone the putative p53REs into a luciferase reporter and to characterize the transcription of these p53REs in glioblastoma (U87 MG) and human embryonic kidney (HEK293) cell lines. Through the transactivation assay, it was discovered that p53REs 2 and 3 were functional in HEK293, but none of the response elements were functional in U87 MG. Since p53 displayed a different regulatory capacity of HR expression in HEK293 and U87 MG cells, the second aim was to verify whether the p53REs are mutated in GBM U87 MG cells by genomic DNA sequencing.
ContributorsMaatough, Anas (Author) / Neisewander, Janet (Thesis director) / Hsieh, Jui-Cheng (Committee member) / Goldstein, Elliott (Committee member) / School of Life Sciences (Contributor) / School of Historical, Philosophical and Religious Studies (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05