Matching Items (322)
Description
The development of the Diabetic Physiological state is influenced by the Receptor for Advanced Glycation End Products (RAGE). This receptor was discovered in 1992, and the accumulation of research on this subject has been extensive. Structural characterization studies of the RAGE protein have shown that it is a transmembrane protein that binds a number of different motile ligands. The diversity of ligands that can attach to the binding domain is the primary factor that allows for RAGE to exhibit its wide-range effects on host cells. Two different studies were completed: one study dealt with the role of IAPP in beta cell death, and the second study was related to RAGE influence on cardiomyocytes and, more specifically, it was related to cardiac cell death. After the completion of the two studies, a comprehensive report was written for each topic. The two papers were merged into a single document. Molecular studies are important for understanding the underlying mechanisms that motivate pathophysiological presentation. In addition to a molecular understanding of the development of diabetes, a clinical research study was completed through the examination of appropriate literature sources. This clinical aspect allowed for the progression of different phases in the research process. A relationship between vinegar and lower plasma glucose was found. The exact mechanism behind this relationship will be studied in the future.
ContributorsGonzalez, Matthew Joseph (Author) / Johnston, Carol (Thesis director) / Collins, Michael (Committee member) / Barrett, The Honors College (Contributor) / School of Nutrition and Health Promotion (Contributor)
Created2015-05
Description
Introduction/Purpose: the purpose of this study was to explore the perception of care after stillbirth and the use of physical activity and/or mindful approaches (e.g., yoga) to cope with grief in women of racial/ethnic minority who have experienced stillbirth.
Methods: This was an exploratory qualitative research study. Participants were African American, Hispanic, Asian, and American Indian women, between the ages of 26 and 38, who have experienced stillbirth within the past 3 years. Participants completed a 20-30 minute phone interview.
Results: Fourteen women participated in the study (M age = 31.02 ± 5.97 years; M time since stillbirth = 1.47 ± 0.94 years). Women’s perceptions about physical activity and mindfulness to cope with grief were coded into the following major themes: perception of health care after stillbirth (satisfaction with the level of care provided), recommendations about inter-conception health care from physician (relating to mental, emotional, and physical health), grief (comfort with communicating with the physician), coping mechanisms, perception of the relationship between physical activity and mood, barriers to participating in physical activity (social and behavioral), pre-pregnancy physical activity, and perception of mindful approach (e.g., yoga) as a coping mechanism.
Conclusion: This was the first study to explore perceptions of health care and the use of physical activity and/or mindful approaches (e.g., yoga) to cope with grief after stillbirth in women of racial/ethnic minority. Findings from this study may help inform health care professionals alter their care practices and introduce physical activity and mindfulness based approaches as coping mechanisms to mothers of stillborn babies.
Methods: This was an exploratory qualitative research study. Participants were African American, Hispanic, Asian, and American Indian women, between the ages of 26 and 38, who have experienced stillbirth within the past 3 years. Participants completed a 20-30 minute phone interview.
Results: Fourteen women participated in the study (M age = 31.02 ± 5.97 years; M time since stillbirth = 1.47 ± 0.94 years). Women’s perceptions about physical activity and mindfulness to cope with grief were coded into the following major themes: perception of health care after stillbirth (satisfaction with the level of care provided), recommendations about inter-conception health care from physician (relating to mental, emotional, and physical health), grief (comfort with communicating with the physician), coping mechanisms, perception of the relationship between physical activity and mood, barriers to participating in physical activity (social and behavioral), pre-pregnancy physical activity, and perception of mindful approach (e.g., yoga) as a coping mechanism.
Conclusion: This was the first study to explore perceptions of health care and the use of physical activity and/or mindful approaches (e.g., yoga) to cope with grief after stillbirth in women of racial/ethnic minority. Findings from this study may help inform health care professionals alter their care practices and introduce physical activity and mindfulness based approaches as coping mechanisms to mothers of stillborn babies.
ContributorsArvayo, Jordan Michelle (Author) / Huberty, Jennifer (Thesis director) / Hoffner, Kristin (Committee member) / Barrett, The Honors College (Contributor) / School of Nutrition and Health Promotion (Contributor)
Created2015-05
Effects of Assisted Cycle Therapy on Short Term and Working Memory in Adolescents with Down Syndrome
Description
To examine the effect of an 8-week cycling intervention on short term and working memory in adolescents with Down syndrome (DS), participants were divided into Assisted Cycling Therapy (ACT), Voluntary Cycling (VC), or No Cycling (NC) groups. Forward and backward digit span assessments were administered prior to and after the intervention to evaluate short term and working memory respectively. 8 weeks of exercise via ACT showed a trend toward conventional levels of significance in the number of levels completed in the backward direction.
ContributorsSandoval-Menendez, Amber Melanie (Author) / Ringenbach, Shannon (Thesis director) / Amazeen, Eric (Committee member) / Blais, Chris (Committee member) / Barrett, The Honors College (Contributor) / School of Nutrition and Health Promotion (Contributor)
Created2015-05
Description
This study examined the effect of an 8-week exercise intervention on functional exercise capacity in adolescents with Down syndrome (DS). Forty participants were randomly assigned to one of three groups: assisted cycling (ACT) (n = 17) where participants experienced at least a 35% increase in their voluntary cycling speed through the use of a motor, voluntary cycling (VC) (n = 15) where participants cycled at a self-selected cadence, and no cycling (NC) (n = 8) where participants did not participate in any cycling intervention. In each cycling intervention, each participant completed three, 30 minute cycling sessions per week for a total of eight weeks. The Six-Minute Walk Test (6MWT) was administered prior to and after the 8-week intervention in pre-test and post-test assessment sessions, respectively. Our hypothesis was somewhat supported in that functional exercise capacity improved after ACT as measured by an increase in total number of laps walked, total distance walked, and average walking speed during the 6MWT, when compared to VC or NC.
ContributorsCook, Megan Rey (Author) / Ringenbach, Shannon (Thesis director) / Huberty, Jennifer (Committee member) / Barrett, The Honors College (Contributor) / School of Nutrition and Health Promotion (Contributor)
Created2015-05
Description
Many studies have supported the theory that gain-framed messaging is effective in changing smoking behavior. However, the importance of focusing on long-term positive benefits or short-term positive benefits in this messaging remains a mystery. This study investigated the role that reward-delay within gain-framed messaging has on the self-esteem and behavior of cigarette smokers. Specifically, it sought to answer the question of whether short-term reward-delay messaging is more effective in increasing self-esteem and positive smoking behavior than long-term reward-delay messaging. An intervention was conducted in which participants, 16 female and 17 male, were exposed to either short-term reward-delay information or long-term reward-delay information. Self-esteem scores as well as smoking behavior were measured and compared before and after the intervention. Results from the study showed that participants in the short-term reward-delay group smoked 2 less cigarettes per day and 12 less cigarettes per week on average after the intervention than participants in the long-term reward-delay group. The results were also consistent with the findings of previous studies that suggest females are more heavily influenced by gain-framed messaging than males.
ContributorsHintze, Kellie Elizabeth (Author) / Chisum, Jack W. (Thesis director) / Brown, Carla J. (Committee member) / Barrett, The Honors College (Contributor) / School of Nutrition and Health Promotion (Contributor) / Department of Psychology (Contributor)
Created2015-05
Description
This study examines cognitive and motor function in adolescents with Down syndrome (DS) following an 8-week assisted cycling therapy intervention. Forty-four participants were randomly assigned to three groups consisting of an assisted cycling (AC) (i.e., exercise accomplished through the use of a motor), a voluntary cycling (VC) (self-selected cadence), and a no cycling (NC) control group. Both ACT and VC groups rode a stationary bicycle for three 30-minute sessions a week, for a total of eight weeks. Participants completed cognitive testing that assessed information processing and manual dexterity at the beginning and at the end of the 8-week intervention. Consistent with our hypothesis, the results showed that information processing and manual dexterity improved following 8 weeks of cycling for the ACT group. These results were not seen for individuals in the voluntary and non-exercise groups. Our results suggest that assisted cycling therapy may induce permanent changes in the prefrontal cortex in adolescents with DS.
ContributorsJimenez, Andrew (Author) / Ringenbach, Shannon (Thesis director) / Kulinna, Pamela (Committee member) / Barrett, The Honors College (Contributor) / School of Nutrition and Health Promotion (Contributor)
Created2015-05
Description
Ruptures in the anterior cruciate ligament are a prevalent injury, particularly in young athletes. This injury is frequently treated with surgical repair utilizing autologous tissue, cadaver allografts or synthetic grafts. However there is no definitive answer on which is the best graft option. This review aims to compare clinical results of patellar tendon autograft (PT), hamstring autograft (HT), cadaver allograft and LARS synthetic ligament in ACL reconstruction. The ASU library was systematically searched for comparison studies or meta-analyses that compared or described ACL reconstruction graft options. The results of the studies were analyzed according to re-tear rate, return to pre-injury level of activity, KT-1000 laxity scores, post-operative muscle strength, International Knee Documentation Committee Score (IKDC), Lysholm score, Lachman test and donor site morbidity. Allografts showed the highest re-tear rate and increase in laxity when compared with the PT autograft and HT autograft. PT autograft provided the most stability according to the KT-1000 results. Knee extensor muscle strength was not graft dependent, but knee flexor strength decreased significantly in HT autograft patients. All grafts showed comparable results for IKDC, Lysholm scores and Lachman tests. There was increased anterior knee pain in PT autograft patients however this did not seem to have an affect on the stability or durability of the graft. The PT autograft is the best choice for individuals undergoing ACL reconstruction on the basis of lower re-tear rates and greater joint stability.
ContributorsNormen, Eliza Armstrong (Author) / Broman, Tannah (Thesis director) / Harper, Erin (Committee member) / Barrett, The Honors College (Contributor) / School of Nutrition and Health Promotion (Contributor) / School for the Science of Health Care Delivery (Contributor)
Created2015-05
Description
Previous research has found improvements in motor control following Assisted Cycle Therapy (ACT) in persons with Parkinson's disease, Down syndrome (DS) and autism. Our study examined the effect of ACT on manual dexterity in adults with Attention Deficit Hyperactivity Disorder (ADHD). Nine adults with ADHD completed six weeks of light intensity cycling on a stationary bicycle, three times per week for 30 minutes. Four adults with ADHD were in the voluntary cycling (VC) group in which they pedaled at their self-selected rate. Five adults with ADHD were in the ACT group in which a motor moved their legs at a rate approximately 13% faster than their voluntary rate. Our results showed that the dominant hand moved more pegs following ACT than VC. Our results were interpreted with respect to upregulation of neurotrophic factors in the motor cortex following ACT.
ContributorsRupp, Emily Anne (Author) / Ringenbach, Shannon (Thesis director) / Caterino, Linda (Committee member) / Broman, Tannah (Committee member) / Barrett, The Honors College (Contributor) / School of Nutrition and Health Promotion (Contributor)
Created2016-05
Description
The intention of this thesis is to create a cookbook to best serve the needs of all who attend Lions Camp Tatiyee. The cookbook was used as a resource in providing the Lions Camp Tatiyee Kitchen staff with simple, healthy recipes to use in the implementation of their summer menu. This thesis discusses the culmination of the idea, the process of execution, current research concerning the relationship between nutrition and health concerns related to special needs, and achievements and further advancements of my creative project.
ContributorsCornella, Krystiana Mana (Author) / Lespron, Christy (Thesis director) / Dixon, Kathleen (Committee member) / Barrett, The Honors College (Contributor) / School of Nutrition and Health Promotion (Contributor)
Created2015-12
Description
Popular culture has a longstanding tendency for being affected by, and reversely affecting, politics. Films, in particular, can exist as either purse “escapism” or heady pathways for political commentary. During the Second World War, governments in both the United States and Great Britain used film as a vessel for their own messages, but after the war ended, the two nations allowed their respective film industries more free expression in commenting on wartime and post-war politics. Film also provided particularly vivid political commentary during, and in the years immediately following, the Cold War. Though film has a longstanding history of being a force for political commentary, the medium’s specific engagement with the Cold War holds particular significance because works produced by the two nations’ film industries paralleled the social trend toward political activism at the time. While films produced in the UK and the United States in the 1960s addressed a wide range of contentious political issues, a huge body of work was spurred on by one of the most pressing political tensions of the time: namely, the Cold War.
The United States and Great Britain were major, allied forces during the Cold War. Despite their allied positions, they had unique politico-social perspectives that greatly reflected their immediate involvement in the conflict, in addition to their respective political histories and engagement in previous wars. As the Cold War threat was a large and, in many ways, incomprehensible one, each country took certain elements of the Cold War situation and used those elements to reflect their varied political social positions to a more popular audience and the culture it consumed.
In turn, filmmakers in both countries used their mediums to make overarching political commentaries on the Cold War situation. This analysis looks at five films from those countries during the 1960s, and explores how each representation offered different, often conflicting, perspectives on how to “manage” Cold War tensions, while simultaneously reflecting their conflicted culture and political decisions. The films analyzed reveal that each country focused on contrasting perceptions about the source of the threat posed by Soviet forces, thus becoming tools to further promote their distinct political stances. While the specifics of that commentary changed with each filmmaker, they generally paralleled each country’s perspective on the overall Cold War atmosphere. The British message represented the Cold War as a very internal battle—one that involved the threat within UK borders via the infiltration of spies the tools of espionage. In contrast, the American films suggest that the Cold War threat was largely an internal one, a struggle best combatted by increasing weaponry that would help control the threat before it reached American borders.
The United States and Great Britain were major, allied forces during the Cold War. Despite their allied positions, they had unique politico-social perspectives that greatly reflected their immediate involvement in the conflict, in addition to their respective political histories and engagement in previous wars. As the Cold War threat was a large and, in many ways, incomprehensible one, each country took certain elements of the Cold War situation and used those elements to reflect their varied political social positions to a more popular audience and the culture it consumed.
In turn, filmmakers in both countries used their mediums to make overarching political commentaries on the Cold War situation. This analysis looks at five films from those countries during the 1960s, and explores how each representation offered different, often conflicting, perspectives on how to “manage” Cold War tensions, while simultaneously reflecting their conflicted culture and political decisions. The films analyzed reveal that each country focused on contrasting perceptions about the source of the threat posed by Soviet forces, thus becoming tools to further promote their distinct political stances. While the specifics of that commentary changed with each filmmaker, they generally paralleled each country’s perspective on the overall Cold War atmosphere. The British message represented the Cold War as a very internal battle—one that involved the threat within UK borders via the infiltration of spies the tools of espionage. In contrast, the American films suggest that the Cold War threat was largely an internal one, a struggle best combatted by increasing weaponry that would help control the threat before it reached American borders.
ContributorsNelson, Taylor Lynn (Author) / Miller, April (Thesis director) / O'Flaherty, Katherine (Committee member) / Walter Cronkite School of Journalism and Mass Communication (Contributor) / School of Historical, Philosophical and Religious Studies (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05