Matching Items (162)
Description
It is important to consider factors that contribute to successful fertilization and the development of viable offspring. Better understanding the factors that contribute to infertility can be used to assist in the development of viable offspring, especially for human beings looking to successfully reproduce. Identifying paternal effect genes, genes that come from the father, introduces more targets that can be manipulated to produce specific reproductive effects. Use of Drosophila melanogaster as a model to study reproduction has increased, in part, due to the use of the GAL4 system. In this system, the GAL4 gene encodes an 881 amino acid protein that binds to the 4-site Upstream Activating Sequence (UAS) to induce transcription of the gene of interest. These sequences constitute the two components of the system: the driver (GAL4) and the responder (gene of interest) \u2014 each of which is maintained as a separate parental line. Effects of the GAL4 driver line "driving" transcription of the responder can be assessed by examining the offspring. One of the more common uses of the GAL4 system involves analyzing phenotypic effects of reducing or eliminating expression of a target gene through the induction of RNAi transcription, which often results in toxicity, lethality, or reduced viability. Utilizing these principles, we strove to demonstrate the effect of knocking down the expression of testis-specific sperm-leucyl-aminopeptidases gene CG13340 on progeny by inducing expression of RNAi with two distinct GAL4 driver lines - one with a nonspecific actin-binding activation sequence and the other with a testis-specific activation sequence. Comparison of both GAL4 driver lines to crosses using N01 wild type ("wt") flies verify that inducing RNAi transcription using the GAL4 system results in reduction of proper offspring development. Further studies using D. melanogaster and the GAL4 system can improve knowledge of factors contributing to male fertility and also be applied to better understand mammalian, specifically human, fertility.
ContributorsEvans, Donna Marie (Author) / Karr, Timothy L. (Thesis director) / Roland, Kenneth (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor) / Department of English (Contributor)
Created2014-05
Description
Currently, autonomous vehicles are being evaluated by how well they interact with humans without evaluating how well humans interact with them. Since people are not going to unanimously switch over to using autonomous vehicles, attention must be given to how well these new vehicles signal intent to human drivers from the driver’s point of view. Ineffective communication will lead to unnecessary discomfort among drivers caused by an underlying uncertainty about what an autonomous vehicle is or isn’t about to do. Recent studies suggest that humans tend to fixate on areas of higher uncertainty so scenarios that have a higher number of vehicle fixations can be reasoned to be more uncertain. We provide a framework for measuring human uncertainty and use the framework to measure the effect of empathetic vs non-empathetic agents. We used a simulated driving environment to create recorded scenarios and manipulate the autonomous vehicle to include either an empathetic or non-empathetic agent. The driving interaction is composed of two vehicles approaching an uncontrolled intersection. These scenarios were played to twelve participants while their gaze was recorded to track what the participants were fixating on. The overall intent was to provide an analytical framework as a tool for evaluating autonomous driving features; and in this case, we choose to evaluate how effective it was for vehicles to have empathetic behaviors included in the autonomous vehicle decision making. A t-test analysis of the gaze indicated that empathy did not in fact reduce uncertainty although additional testing of this hypothesis will be needed due to the small sample size.
ContributorsGreenhagen, Tanner Patrick (Author) / Yang, Yezhou (Thesis director) / Jammula, Varun C (Committee member) / Computer Science and Engineering Program (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
Description
In the last decade, a large variety of algorithms have been developed for use in object tracking, environment mapping, and object classification. It is often difficult for beginners to fully predict the constraints that multirotors place on machine vision algorithms. The purpose of this paper is to explain some of the types of algorithms that can be applied to these aerial systems, why the constraints for these algorithms exist, and what could be done to mitigate them. This paper provides a summary of the processes involved in a popular filter-based tracking algorithm called MOSSE (Minimum Output Sum of Squared Error) and a particular implementation of SLAM (Simultaneous Localization and Mapping) called LSD SLAM.
ContributorsVan Hazel, Colton (Author) / Zhang, Wenlong (Thesis director) / Yang, Yezhou (Committee member) / Engineering Programs (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
A defense-by-randomization framework is proposed as an effective defense mechanism against different types of adversarial attacks on neural networks. Experiments were conducted by selecting a combination of differently constructed image classification neural networks to observe which combinations applied to this framework were most effective in maximizing classification accuracy. Furthermore, the reasons why particular combinations were more effective than others is explored.
ContributorsMazboudi, Yassine Ahmad (Author) / Yang, Yezhou (Thesis director) / Ren, Yi (Committee member) / School of Mathematical and Statistical Sciences (Contributor) / Economics Program in CLAS (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
Propaganda bots are malicious bots on Twitter that spread divisive opinions and support political accounts. This project is based on detecting propaganda bots on Twitter using machine learning. Once I began to observe patterns within propaganda followers on Twitter, I determined that I could train algorithms to detect these bots. The paper focuses on my development and process of training classifiers and using them to create a user-facing server that performs prediction functions automatically. The learning goals of this project were detailed, the focus of which was to learn some form of machine learning architecture. I needed to learn some aspect of large data handling, as well as being able to maintain these datasets for training use. I also needed to develop a server that would execute these functionalities on command. I wanted to be able to design a full-stack system that allowed me to create every aspect of a user-facing server that can execute predictions using the classifiers that I design.
Throughout this project, I decided on a number of learning goals to consider it a success. I needed to learn how to use the supporting libraries that would help me to design this system. I also learned how to use the Twitter API, as well as create the infrastructure behind it that would allow me to collect large amounts of data for machine learning. I needed to become familiar with common machine learning libraries in Python in order to create the necessary algorithms and pipelines to make predictions based on Twitter data.
This paper details the steps and decisions needed to determine how to collect this data and apply it to machine learning algorithms. I determined how to create labelled data using pre-existing Botometer ratings, and the levels of confidence I needed to label data for training. I use the scikit-learn library to create these algorithms to best detect these bots. I used a number of pre-processing routines to refine the classifiers’ precision, including natural language processing and data analysis techniques. I eventually move to remotely-hosted versions of the system on Amazon web instances to collect larger amounts of data and train more advanced classifiers. This leads to the details of my final implementation of a user-facing server, hosted on AWS and interfacing over Gmail’s IMAP server.
The current and future development of this system is laid out. This includes more advanced classifiers, better data analysis, conversions to third party Twitter data collection systems, and user features. I detail what it is I have learned from this exercise, and what it is I hope to continue working on.
Throughout this project, I decided on a number of learning goals to consider it a success. I needed to learn how to use the supporting libraries that would help me to design this system. I also learned how to use the Twitter API, as well as create the infrastructure behind it that would allow me to collect large amounts of data for machine learning. I needed to become familiar with common machine learning libraries in Python in order to create the necessary algorithms and pipelines to make predictions based on Twitter data.
This paper details the steps and decisions needed to determine how to collect this data and apply it to machine learning algorithms. I determined how to create labelled data using pre-existing Botometer ratings, and the levels of confidence I needed to label data for training. I use the scikit-learn library to create these algorithms to best detect these bots. I used a number of pre-processing routines to refine the classifiers’ precision, including natural language processing and data analysis techniques. I eventually move to remotely-hosted versions of the system on Amazon web instances to collect larger amounts of data and train more advanced classifiers. This leads to the details of my final implementation of a user-facing server, hosted on AWS and interfacing over Gmail’s IMAP server.
The current and future development of this system is laid out. This includes more advanced classifiers, better data analysis, conversions to third party Twitter data collection systems, and user features. I detail what it is I have learned from this exercise, and what it is I hope to continue working on.
ContributorsPeterson, Austin (Author) / Yang, Yezhou (Thesis director) / Sadasivam, Aadhavan (Committee member) / Computer Science and Engineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
In the field of machine learning, reinforcement learning stands out for its ability to explore approaches to complex, high dimensional problems that outperform even expert humans. For robotic locomotion tasks reinforcement learning provides an approach to solving them without the need for unique controllers. In this thesis, two reinforcement learning algorithms, Deep Deterministic Policy Gradient and Group Factor Policy Search are compared based upon their performance in the bipedal walking environment provided by OpenAI gym. These algorithms are evaluated on their performance in the environment and their sample efficiency.
ContributorsMcDonald, Dax (Author) / Ben Amor, Heni (Thesis director) / Yang, Yezhou (Committee member) / Barrett, The Honors College (Contributor) / Computer Science and Engineering Program (Contributor)
Created2018-12
iLieDown - Improved Display Orientation For Handheld Devices Using Convolutional Neural Networks.pdf
Description
91% of smartphone and tablet users experience a problem with their device screen being oriented the wrong way during use [11]. In [11], the authors proposed iRotate, a previous solution which uses computer vision to solve the orientation problem. We propose iLieDown, an improved method of automatically rotating smartphones, tablets, and other device displays. This paper introduces a new algorithm to correctly orient the display relative to the user’s face using a convolutional neural network (CNN). The CNN model is trained to predict the rotation of faces in various environments through data augmentation, uses a confidence threshold, and analyzes multiple images to be accurate and robust. iLieDown is battery and CPU efficient, causes no noticeable lag to the user during use, and is 6x more accurate than iRotate.
ContributorsTallman, Riley Paul (Author) / Yang, Yezhou (Thesis director) / Fang, Zhiyuan (Committee member) / Computer Science and Engineering Program (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2019-12
Description
Students learn in various ways \u2014 visualization, auditory, memorizing, or making analogies. Traditional lecturing in engineering courses and the learning styles of engineering students are inharmonious causing students to be at a disadvantage based on their learning style (Felder & Silverman, 1988). My study analyzes the traditional approach to learning coding skills which is unnatural to engineering students with no previous exposure and examining if visual learning enhances introductory computer science education. Visual and text-based learning are evaluated to determine how students learn introductory coding skills and associated problem solving skills. My study was conducted to observe how the two types of learning aid the students in learning how to problem solve as well as how much knowledge can be obtained in a short period of time. The application used for visual learning was Scratch and Repl.it was used for text-based learning. Two exams were made to measure the progress made by each student. The topics covered by the exam were initialization, variable reassignment, output, if statements, if else statements, nested if statements, logical operators, arrays/lists, while loop, type casting, functions, object orientation, and sorting. Analysis of the data collected in the study allow us to observe whether the traditional method of teaching programming or block-based programming is more beneficial and in what topics of introductory computer science concepts.
ContributorsVidaure, Destiny Vanessa (Author) / Meuth, Ryan (Thesis director) / Yang, Yezhou (Committee member) / Computer Science and Engineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
All of the modern technology tools that are being used today, have a purpose to support a variety of human tasks. Ambient Intelligence is the next step to transform modern technology. Ambient Intelligence is an electronic environment that is sensitive and responsive to human interaction/activity. We understand that Ambient Intelligence(AmI) concentrates on connectivity within a person's environment and the purpose of having a new connection is to make life simpler. Today, technology is in the transition of a new lifestyle where technology is discretely living with us. Ambient Intelligence is still in progress, but we can analyze the technology we have today, ties a relationship with Ambient Intelligence. In order to examine this concern, I investigated how much awareness/knowledge users that range from Generation X to Xennials, that had experience from replacing habitual items and technologies they use on a daily basis. A few questions I mainly wanted answered: - What kind of technologies, software, or tech services replace items you use daily? - What kind of benefits did the technology give you, did it change the way you think/act on any kind of activities? - What kind of expectations/concerns do you have for future technologies? To accomplish this, I gathered information from interviewing multiples groups: millennials and other older generations (33+ years old). I retrieved data from students at Arizona State University, Intel Corporation, and a local clinic. From this study, I've discovered from both groups, that both sides agree that modern technology is rapidly growing to a point that computers think as humans. Through multiple interviews and research, I have found that the technology today makes an impact through all aspects of our lives and through artificial intelligence. Furthermore, I will discuss and predict what will society will encounter later on as the new technology discretely arises.
ContributorsPascua, Roman Paolo Bustos (Author) / Yang, Yezhou (Thesis director) / Caviedes, Jorge (Committee member) / Computer Science and Engineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
This thesis examines Care Not Cash, a welfare reform measure that replaced traditional cash General Assistance program payments for homeless persons in San Francisco with in-kind social services. Unlike most welfare reform measures, proponents framed Care Not Cash as a progressive policy, aimed at expanding social services and government care for this vulnerable population. Drawing on primary and secondary documents, as well as interviews with homelessness policy experts, this thesis examines the historical and political success of Care Not Cash, and explores the potential need for implementation of a similar program in Phoenix, Arizona.
ContributorsMcCutcheon, Zachary Ryan (Author) / Lucio, Joanna (Thesis director) / Williams, David (Committee member) / Bretts-Jamison, Jake (Committee member) / School of Public Affairs (Contributor) / Barrett, The Honors College (Contributor)
Created2017-05