Matching Items (2)
Description
The main objective of this study was to use a genetically-informative design to examine the putative influences of maternal perceived prenatal stress, obstetrical complications, and gestational age on infant dysregulation, competence, and developmental maturity. Specifically, whether or not prenatal and obstetrical environmental conditions modified the heritability of infant outcomes was examined. A total of 291 mothers were interviewed when their twin infants were 12 months of age. Pregnancy and twin birth medical records were obtained to code obstetrical data. Utilizing behavioral genetic models, results indicated maternal perceived prenatal stress moderated genetic and environmental influences on developmental maturity whereas obstetrical complications moderated shared environmental influences on infant competence and nonshared environmental influences on developmental maturity. Gestational age moderated the heritability and nonshared environment of infant dysregulation, shared and nonshared environmental influences on competence, and nonshared environmental influences on developmental maturity. Taken together, prenatal and obstetric conditions were important nonlinear influences on infant outcomes. An evolutionary perspective may provide a framework for these findings, such that the prenatal environment programs the fetus to be adaptive to current environmental contexts. Specifically, prenatal stress governs gene expression through epigenetic processes. Findings highlight the utility of a genetically informative design for elucidating the role of prenatal and obstetric conditions in the etiology of infant developmental outcomes.
ContributorsMcDonald, Kristy (Author) / Lemery-Chalfant, Kathryn S (Thesis advisor) / Fabricius, William (Committee member) / Luecken, Linda (Committee member) / Spinrad, Tracy (Committee member) / Arizona State University (Publisher)
Created2011
Description
The relations between prenatal risk factors and postnatal risk and protective factors and infant outcomes were examined. Mothers, primarily of low-income background and Latina ethnicity, were interviewed within 24 hours of giving birth, and then again when their infants were five and nine months of age. The relations between prenatal stress, postnatal environment, and infant maturity and temperament were analyzedusing a multiple regression model. We controlled for the covariates: mother's education level and infant's birth weight. Maternal prenatal risk factors predicted lower infant Regulation and lower Developmental Maturity at nine months. Maternal postnatal risks did not predict infant outcomes, but maternal expectations for their child provided a significant association for three of the four infant outcomes: Regulation, Surgency, and Infant Developmental Maturity. The results underscore the importance of prenatal stress holding its significance with the addition of postnatal measures. Future studies would need to explore deeper into a multitude of postnatal factors, in order to accurately portray associations between maternal prenatal stress and infant health.
ContributorsTran, Melissa (Author) / Lemery-Chalfant, Kathryn (Thesis director) / Luecken, Linda (Committee member) / McDonald, Kristy (Committee member) / Barrett, The Honors College (Contributor)
Created2012-05