Matching Items (344)
Description
Adderall remains to be one of the most commonly abused drug among college campuses. Although it is a prescription drug that is primarily used to treat attention deficit hyperactivity disorder (ADHD), it has become one of the many "study drugs" due to its usage among college students during stressful school times, such as exams, where increased concentration and energy levels are thought to improve work efficiency. However, Adderall is notable for having a high potential for abuse and a risk of psychological and physical side effects. In this paper, we conducted a mathematical analysis on an existing epidemiological model of Adderall abuse. We started by verifying the positivity of solutions using techniques from dynamical systems because this is a population model dealing with people. Then, we found and investigated different equilibrium solutions to analyze their stability using both analytical and graphical approaches. Finally, the results were tied back into the Adderall model and conclusions were drawn.
ContributorsKerseg, Cassidy (Author) / Wirkus, Stephen (Thesis director) / Brager, Danielle (Committee member) / School of Mathematical and Natural Sciences (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
Description
In late 2019, COVID-19, a new disease caused by a novel (or new) coronavirus began to take over the lives of many people. This study centers on how members of the Latinx community have been affected by COVID-19. Both quantitative and qualitative data were utilized to analyze the perceived risk of infection, preventative behaviors, and acceptability of the COVID-19 vaccine for individuals that identify as Latinx. Analysis of the survey and interview analysis found the majority of participants expressed abiding by recommended measures and becoming hypervigilant about their activities, and their desire to get vaccinated against COVID-19 when they are eligible. Individuals who did not express the desire to be vaccinated mentioned worries including side effects, costs, safety, and efficacy of the vaccine. Results from this research could aid in the creation of public health initiatives in order to increase the uptake of the vaccine tailored for the Latinx community.
ContributorsJimenez Espinoza, Issa Hibeth (Author) / Gonzales, Angela (Thesis director) / Vargas, Edward (Committee member) / School of Humanities, Arts, and Cultural Studies (Contributor) / School of Mathematical and Natural Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
Description
Vitamin D, Klotho, and FOXO3 have all been linked to have anti-aging and anti-cancerous effects as separate pathways. Specifically, mice with knockout Klotho in their genes have displayed signs of premature aging, humans who are vitamin D deficient have been shown to develop cardiovascular disease and cognitive impairments, and those who have displayed overexpression of FOXO3 have shown to have a longer lifespan. Here we took each pathway and attempted to formulate a feedback mechanism loop linking all three separate pathways. We propose that vitamin D levels modulate klotho activity, including the expression of the s-klotho and m-klotho isoforms. Moreover, the anti-oxidation transcription factor FOXO3 is also thought to participate in crosstalk with VDR signaling. Through the connection between 1,25D and Klotho, we probed at their interactions with FOXO3 signaling in kidney and colon cells, and proposed that vitamin D and klotho may reduce oxidative stress and suppress the onset of epithelial cancers through it effects on FOXO3. Results showed a strong support for the cooperation between FOXO3 and 1,25D to stimulate both superoxide dismutase (a FOXO3 response element) and XDR3/ROC (vitamin D response elements). This cooperation was mostly seen in embryonic kidney cells (HEK293) and not in the colon cancer cells (HCT116), which has led to the conclusion that vitamin D and FOXO3 cooperation mainly occurs in kidney tissue and/or in tissue that is not yet been overtaken by cancer. Differences in the Klotho isoforms were seen when measuring FOXO3 and vitamin D activity, but experiments manipulating other components will need to be conducted to further understand the function of Klotho in maintaining reactive oxygenated species levels.
ContributorsSandoval, Ruby (Author) / Jurutka, Peter (Thesis director) / Sandrin, Todd R. (Committee member) / Heck, Michael (Committee member) / School of Social and Behavioral Sciences (Contributor) / School of Mathematical and Natural Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
The Athleta Esprit de She is a national women's racing series owned and produced by Life Time Athletic Events, a branch of the company Life Time Fitness. Esprit de She (EDS) has fourteen events per year in areas ranging from Minneapolis, MN to San Diego, CA. These events include 5K/10K runs, triathlons, duathlons, and cycle tours. The purpose of this study was to determine recommendations for the brand from both a marketing and event production standpoint. Through the use of a survey, the research team received participant feedback regarding the events. Once receiving participant survey responses, the research team used Importance-Performance Analysis to analyze the data. The goals of the study were to see how participants perceive the production of the event as well as the social media presence of the brand. Participants also provided insights as to whether or not they are ready to accept a greater challenge with a longer distance race. The overall aim of this study was to see what changes needed to be made to both the brand as well as the events themselves in order to improve the overall customer experience with Esprit de She.
ContributorsFlanagan, Kelly Lynn (Author) / Hultsman, Wendy (Thesis director) / Montoya, Detra (Committee member) / Barrett, The Honors College (Contributor) / School of Community Resources and Development (Contributor) / WPC Graduate Programs (Contributor) / Department of Marketing (Contributor) / W. P. Carey School of Business (Contributor) / Department of Psychology (Contributor)
Created2015-05
Description
In an industrialized world that relies heavily on low cost production and packaging produced without a viable end-of-life strategy, the accumulation of non-biodegradable plastics in the environment and particularly the oceans today is an urgent problem of global proportions. Plastics pose a significant threat to marine mammals due to mistaken ingestion as well as potential release of plasticizers and other chemicals. However, the interactions and consequences of ingestion of oceanic plastics by marine mammals have not been thoroughly studied. In this literature review, information regarding plastic ingestion by marine mammals was compiled to estimate the magnitude of adverse impacts and identify major knowledge gaps. Using comprehensive Boolean search terms in Web of Science of literature published between 1960 and 2020, it was determined that there were large discrepancies in the amount of research conducted among 10 different categories of marine mammals, with cetaceans being the primary focus group of most studies (70.3). In addition, different areas of the world, such as southern Africa, were found to have a disproportionately small number of studies on plastic impacts on marine mammalian life in their surrounding marine waters. Differences were found in the amount of plastics ingested by marine animals and a hypothesis of explaining these observations was formulated, attributing potential ingestion of plastic to the debris resembling different food sources in the mammals’ diets as well as different feeding mechanisms.
ContributorsFredette-Roman, Cassidy (Author) / Polidoro, Beth (Thesis director) / Rolsky, Charles (Committee member) / Halden, Rolf (Committee member) / School of Life Sciences (Contributor) / School of Mathematical and Natural Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2020-12
Description
The purpose of this project is to use powerful visual storytelling techniques to convey a social need and an effective solution. Guatemala is a third world country, where poverty is widespread and the birth rate is high. Among the most economically and educationally disadvantaged are the Mayan women. Arizona nun, Sister Marife Hellman, recognized the needs of this population and founded a school to serve them. Hellman's mission is to provide a quality education to those underserved, so they can become positive leaders in their native communities. The website and video materials produced for this thesis are meant to be used for fundraising purposes on behalf of the school. All funds raised will help Hellman's alumni launch schools in their native areas, giving access to education that has long been nonexistent. Watch the mini-documentary here: www.youtube.com/watch?v=LxTiuwQCH44&t=17s.
ContributorsLaduke, Sierra Dawn (Author) / Craft, John (Thesis director) / Mork, Nick (Committee member) / Walter Cronkite School of Journalism and Mass Communication (Contributor) / School of Community Resources and Development (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
This study examines the utility of diagnostic CT scans as sources of data to quantify facial growth in children. Subadults often suffer facial trauma arising from a variety of circumstances. Pediatric surgeons are then confronted with devising surgical pre- and post-operative strategies that present numerous complications. One of these involves predicting how specific areas of a child's face will change with time. The proliferation of CT scans use in pre-operative planning throughout healthcare provides potential data for addressing many concerns, including those involving facial growth. To add to the burgeoning body of literature focusing on facial growth and provide insight anatomical variation this study used data derived from CT scans from Phoenix Children's Hospital. Quantitative data derived from CTs were used to examine normative growth and develop predictive equations that surgeons can use to visualize facial change for males and female patients.
ContributorsLee, Isaac Jet (Author) / Ferry, Lara (Thesis director) / Falsetti, Anthony (Committee member) / School of Mathematical and Natural Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2018-12
Description
Post-mortem interval (PMI) estimation is a crucial piece of information to be established to be established in any death investigation. Though a variety of methods to estimate PMI exists, not all of them are always able to work. Forensic microbiology is attempting to help bridge this gap by developing methods to predict PMI with microbial communities. The change in the microbiome present on a body after death is a predictable patter that can be used almost like a clock. Existing studies thus far have shown a consistent pattern of what the composition of the microbiome on a body is during key stages of decomposition. However, research has yet to be conducted on whether these patterns persist in an arid climate, such as the desert, or during decomposition within a sealed container. Here, we aimed to begin filling this knowledge gap by observing the microbiomes present on pigs decomposing inside of buckets in the Arizona climate. Bacteroidetes, Firmicutes and Proteobacteria were the most abundant phyla detected with Firmicutes primarily being found on the skin. Firmicutes abundance decreased about half-way through decomposition. Xanthomonadaceae appeared part way through decomposition and Clostridiaceae was detected in all sequenced samples. Though the initial results match the trends established in previous research, further testing is required to determine if this result is reproducible and reliable.
ContributorsMiller, Amber (Author) / Parrott, Jonathan (Thesis director) / Marshall, Pamela (Committee member) / Barrett, The Honors College (Contributor) / School of Mathematical and Natural Sciences (Contributor)
Created2024-05
Description
In an increasingly technological world, people are spending more time inside than ever and less time outside with one another. Our goal is to create a new game that gets people off the couch and on their feet, spending quality time together. Everyone can recall a fond memory where they were outside with friends and family, and we do not want to let that disappear in today’s world.
Three Way is a student-led effort to put an innovative spin on typical lawn games seen at tailgates and backyard barbecues, such as Cornhole and KanJam. Our mission is to bring new life to classic American tailgate games and provide outdoor fun to students and families alike for decades to come.
The tailgate game industry is one that has seen little innovation over time, as favorites like cornhole have been a dominant standout for many years. Even with this lack of new products, this industry has still consistently grown for the last 4 decades, and is projected to continue to grow over the next decade. The global cornhole market is currently $482 million and is forecasted to grow to $1.2 billion by 2033 through a CAGR (compound annual growth rate) of 8.6%. We believe that because of this growth, there is room for a new product in this space. We have created social media accounts on various platforms (Instagram, X) to reach as wide of an audience as possible, along with creating a website and are in the process of designing merchandise to build excitement around our game. The success of our marketing will be dependent on the amount of views we can create.
Our group brings diverse backgrounds to the table with our experience including sports management, marketing, finance, computer information systems, and data analytics. Collectively, we have played a variety of sports in our lives, most notably football, basketball, baseball, golf, and hockey, and are very passionate about sports in general. We believe our extensive experience in sports gives us an advantage over competitors in the industry.
We have developed a prototype that we have utilized at tabling events to obtain consumer feedback. Our goal is to refine our current design until we are satisfied with it prior to releasing it to the public for sale, so profit is currently not our main goal. We have surveyed students before and after playing our game to see the difference between their expectations and the actual game play, and the feedback has been overwhelmingly positive.
ContributorsPonteras, Preston (Author) / Botvinnik, Nicolas (Co-author) / Ilardi, Nicolas (Co-author) / Gaunt, Harrison (Co-author) / Byrne, Jared (Thesis director) / Pierce, John (Committee member) / Barrett, The Honors College (Contributor) / School of Community Resources and Development (Contributor) / Department of Marketing (Contributor) / Department of Information Systems (Contributor)
Created2024-05
Description
This thesis proposes and explores an adapted approach to music recommendation and
event promotion, aimed at providing streaming users more accessibility to local artists,
performers, and events. By focusing specifically on the enrichment of local music ecosystems,
this research is undertaken with the express interest of local music artists, venues, and
streamers in mind. It seeks to serve a multifaceted goal: revitalizing local music scenes by
making them more visible and accessible through streaming platforms; empowering local music artists by providing them with a broader audience and new opportunities for engagement; reconnecting artists with the community, thereby fostering a stronger sense of local identity and cultural cohesion; and providing economic benefit to local venues through increased attendance and engagement. In essence, this thesis intends to harness the power of streaming platforms to rekindle the localized relationships between listeners, artists, and venues, thereby contributing to the renaissance, sustainability, and vibrancy of local music cultures. These outcomes will be achieved through a two-pronged theoretical and practical approach, incorporating Proof of Concept (PoC) algorithm with the Business Model Canvas
(BMC). A Proof of Concept recommendation algorithm was developed as a tool to empirically demonstrate the viability of the proposed strategies. This prototype music recommendation
algorithm was designed and tested with the explicit goal of creating a novel music recommendation algorithm that biased users towards exposure of smaller local artists and
events.
ContributorsBradley, Robert (Author) / Clarkin, Michael (Co-author) / Ellini, Andre (Co-author) / Mancenido, Michelle (Thesis director) / Sirugudi, Kumar (Committee member) / Barrett, The Honors College (Contributor) / School of Mathematical and Natural Sciences (Contributor)
Created2024-05