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The current study examined the unique influence of emotional childhood abuse on positive and negative aspects of different types of social relationships (e.g., family, spouse/partner, and friends) in midlife and whether genetic variations of the oxytocin receptor gene (OXTR) moderated these associations. Genetic variations in OXTR are measured by single-nucleotide

The current study examined the unique influence of emotional childhood abuse on positive and negative aspects of different types of social relationships (e.g., family, spouse/partner, and friends) in midlife and whether genetic variations of the oxytocin receptor gene (OXTR) moderated these associations. Genetic variations in OXTR are measured by single-nucleotide polymorphisms (SNPs), which have been the most substantially studied prospects for explaining individual differences in socio-behavioral phenotypes. Specifically, an SNP, rs53576, involving a guanine (G) to adenine (A) substitution located in the third intron of the OXTR has been associated with fundamental aspects of social processes and behaviors. Compared to A carriers, individuals homozygous for the G allele have enhanced social competencies and tend to elicit more positive responses from social partners, consequently increasing the overall quality of social relationships across the lifespan. However, the G allele of the OXTR has also been associated with greater social sensitivity. In the current study, conducted among a sample of 614 adults in midlife, it was shown that emotional childhood abuse was significantly associated with having less supportive and more strained relationships in midlife. Regarding supportive family relationships, the effect of emotional childhood abuse was moderated by the OXTR rs53576 polymorphism. Specifically, under conditions of more emotional abuse in childhood, individuals homozygous for the G allele had more supportive family relationships in midlife compared to A carriers. Overall, the findings suggest that genetic variations of OXTR rs53576 may be an important candidate in understanding the development of social relationship functioning within the context of negative early life experiences.
ContributorsEbbert, Ashley Marie (Author) / Infurna, Frank (Thesis advisor) / Corbin, William (Committee member) / Lemery, Kathryn (Committee member) / Luthar, Suniya (Committee member) / Arizona State University (Publisher)
Created2018
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Given the major investment young people make in earning and maintaining a peer reputation, our goal in this study was to explore the association between dimensions of negative and positive peer reputation in middle school and adjustment several years later, by the end of high school, among upper middle class

Given the major investment young people make in earning and maintaining a peer reputation, our goal in this study was to explore the association between dimensions of negative and positive peer reputation in middle school and adjustment several years later, by the end of high school, among upper middle class youth. Prior research has shown negative reputations such as aggressive-disruptive and sensitive-isolated to be associated with maladjustment later in life, whereas reputations like popular and prosocial-leader have been related to positive future outcomes. However, there are contrary findings that reveal a more complex relationship between peer reputation and adjustment, showing certain “negative” reputations to be tied with better outcomes in some domains and the converse in others. Using a sample of middle school students, a confirmatory factor analysis (CFA) was performed to test a four-factor model of the Revised Class Play, a peer report measure on peer reputations. CFA findings supported the four-factor model with the following reputations: popular, prosocial, aggressive, and isolated. Structural equation models were used to predict 12th grade adjustment outcomes (academic achievement, psychopathology, substance use) from middle school peer reputation. Prosocial reputation in middle school was connected to higher academic achievement and fewer externalizing symptoms in 12th grade. Both prosocial and isolated peer reputation were negatively associated with alcohol, cigarette, and marijuana use, whereas a popular reputation was related to higher levels of alcohol use. Middle school reputation did not predict internalizing symptoms in 12th grade. Findings are discussed in terms of adaptive and maladaptive adjustment outcomes associated with each peer reputation and implications for future research.
ContributorsCurlee, Alexandria (Author) / Luthar, Suniya (Thesis advisor) / Aiken, Leona (Committee member) / Infurna, Frank (Committee member) / Arizona State University (Publisher)
Created2016
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Description
The purpose of this study was to examine if certain child demographics and risk modifiers of the child (i.e., anxiety sensitivity, depressive symptoms, anxiety control, and social competence) predict program response to a Child Anxiety Indicated Prevention and Early Intervention protocol (Pina, Zerr, Villalta, & Gonzales, 2012). This anxiety protocol

The purpose of this study was to examine if certain child demographics and risk modifiers of the child (i.e., anxiety sensitivity, depressive symptoms, anxiety control, and social competence) predict program response to a Child Anxiety Indicated Prevention and Early Intervention protocol (Pina, Zerr, Villalta, & Gonzales, 2012). This anxiety protocol focused on cognitive behavioral techniques (e.g., systematic and gradual exposure) that used culturally responsive implementation strategies (Pina, Villalta, & Zerr, 2009). The current study aims to investigate specific predictors of program response to this anxiety protocol. First, it was of interest to determine if child demographics and risk modifiers of the child at baseline would predict program response to the early anxiety intervention protocol. Second, it was of interest to see if an interaction with one of the four risk modifiers at baseline and sex or protocol condition would predict program response to the early anxiety intervention protocol. This study included 88 youth (59.14% Hispanic/Latino and 40.9% Caucasian) who were recruited through referrals from public schools and randomized to one of two protocol conditions (i.e., child-only or the child-plus-parent protocol), which had varying levels of mothers’ participation within the Child Anxiety Indicated Prevention and Early Intervention protocol (Pina et al., 2012). Participants ranged from 6 to 17 years of age (M = 10.36, SD = 2.73), and 48.9% were boys. The four risk modifiers were assessed using the Childhood Anxiety Sensitivity Index (CASI; Silverman, Fleisig, Rabian, & Peterson, 1991), Children's Depression Inventory (CDI; Kovacs, 1981), Anxiety Control Questionnaire for Children-Short Form (ACQ-C-S; Weems, 2005), and Social Competence scale from the Child Behavior Checklist (CBCL; Achenbach & Resorla, 2001). Program response was measured by pre-to-posttest changes in anxiety outcomes. Regarding the first aim, each of the four risk modifiers was related to pre-to-posttest changes in program response outcomes. Regarding the second aim for interactions between each of the four focal predictors, sex and protocol condition emerged as moderators. These results have potential implications for clinicians and researchers interested in understanding why some children might experience more or less change when participating in an early intervention protocol for anxiety.
ContributorsWynne, Henry (Author) / Pina, Armando (Thesis advisor) / Luthar, Suniya (Committee member) / Enders, Craig (Committee member) / Wolchik, Sharlene (Committee member) / Arizona State University (Publisher)
Created2017
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Description
In past decades, adverse childhood experiences (ACEs) rapidly gained attentionas a public health crisis due to dose-response relationships with a range of health and social problems, and early mortality. Converging studies show that ACEs are a pandemic in the general population of the United States—even in middle to upper-middle class

In past decades, adverse childhood experiences (ACEs) rapidly gained attentionas a public health crisis due to dose-response relationships with a range of health and social problems, and early mortality. Converging studies show that ACEs are a pandemic in the general population of the United States—even in middle to upper-middle class families that are considered to be ‘better off’. There have been collaborative efforts in public health to target root-causes of childhood adversity and increase resilient adaptation in individuals and families at risk. Due to the importance of fostering positive adaptation in the midst of adversity, this dissertation sought to examine both vulnerability and protective factors in children’s proximal ecology—e.g., parents and caring adults at school. A population-based study in this dissertation revealed that parents’ emotional well-being, measured as negative feelings toward parenting, greatly influences developing children, so as support and resources for parenting. The presence of caring adults as a protective factor in teens with highly competitive settings—a newly identified at-risk group due to high pressure to achieve and internalizing/externalizing problems. Lastly, this dissertation discusses conceptual and methodological limitations in current ways of measuring ACEs and provide future directions for research, practice, and policy. Suggestions include frequent assessments on reaching consensus on how to define ACEs, expanding the concept of ACEs, considering the duration, timing, and severity of the event. Healthcare professionals have important roles in public health; they incorporate frequent assessments on parents’ emotional wellbeing and needs for parenting as a part of care. Ongoing support from multiple disciplines is necessary to reduce the impact of ACEs and strengthen resilience development of children and families.
ContributorsSuh, Bin (Author) / Luthar, Suniya (Thesis advisor) / Pipe, Teri (Thesis advisor) / Castro, Felipe (Committee member) / Arizona State University (Publisher)
Created2022
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Description
The primary goal of this study was to investigate whether youth from an affluent community showed elevated rates of substance use and associated problems in young adulthood relative to national norms. The secondary goal was to determine if parents’ “containment,” or stringent disciplinary action, of adolescent substance use as measured

The primary goal of this study was to investigate whether youth from an affluent community showed elevated rates of substance use and associated problems in young adulthood relative to national norms. The secondary goal was to determine if parents’ “containment,” or stringent disciplinary action, of adolescent substance use as measured in Grade 12 could help predict substance use in senior year of college, over and above other parenting factors. The final goal was to assess trends of substance use over time for stability based on categories of participants’ overall levels of use in Grade 12, (low, medium, high). Results indicated that substance use remained elevated into young adulthood, relative to national norms, consistent with extant research involving upper middle class youth. In regression analyses, high parents’ containment was associated with low substance use in senior year of college; however, the inclusion of Grade12 use as a covariate reduced this association with containment such that it was no longer statistically significant. Such results suggest a mediated effect, with Grade 12 substance use mediating the effects of Grade 12 Containment on college senior year substance use. Finally, upper middle class youth were found to remain in their relative substance use group (low, medium, high) as determined at Grade 12 through all four years of college. Taken together, these results emphasized the importance of high school substance use behaviors as a notable risk factor for problematic substance use over time.
ContributorsSmall, Phillip J (Author) / Luthar, Suniya (Thesis advisor) / Meier, Madeline (Committee member) / Infurna, Frank (Committee member) / Arizona State University (Publisher)
Created2015
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Description
Students at High Achieving Schools (HASs) have recently been identified as an at-risk population, and excessive pressure to excel is considered the cause of this maladjustment. However, the specific aspects of pressure that lead to these outcomes have yet to be comprehensively explored. In two schools, one public and one

Students at High Achieving Schools (HASs) have recently been identified as an at-risk population, and excessive pressure to excel is considered the cause of this maladjustment. However, the specific aspects of pressure that lead to these outcomes have yet to be comprehensively explored. In two schools, one public and one independent, this study examined multiple constructs potentially implicated: feelings of pressure to succeed from different sources (parents, teachers, coaches, the self, and friends) and total felt pressure. Also considered are dimensions of being overextended across commitments, including hours of sleep, homework, and levels of associated strain and enjoyment. These indices were all examined in relation to adolescents’ internalizing and externalizing symptoms, as well as feelings of disengagement with school, after controlling for attachment to both parents. Results showed that total felt pressure, and pressure felt from the self, were most notably related to internalizing symptoms and disengagement with school. Additionally, strain from commitments showed unique links with depression, anxiety, and negative feelings about school. Finally, enjoyment from different commitments showed robust links with feelings about school. Overall, the different pressure predictors showed sporadic links with externalizing behaviors and substance use. Findings are discussed in terms of directions for interventions as well as future research with HAS populations.
ContributorsBenoit, Renee, L (Author) / Luthar, Suniya (Thesis advisor) / Infurna, Frank (Committee member) / Benitez, Viridiana (Committee member) / Arizona State University (Publisher)
Created2019