Matching Items (149)
Description
The knee joint has essential functions to support the body weight and maintain normal walking. Neurological diseases like stroke and musculoskeletal disorders like osteoarthritis can affect the function of the knee. Besides physical therapy, robot-assisted therapy using wearable exoskeletons and exosuits has shown the potential as an efficient therapy that helps patients restore their limbs’ functions. Exoskeletons and exosuits are being developed for either human performance augmentation or medical purposes like rehabilitation. Although, the research on exoskeletons started early before exosuits, the research and development on exosuits have recently grown rapidly as exosuits have advantages that exoskeletons lack. The objective of this research is to develop a soft exosuit for knee flexion assistance and validate its ability to reduce the EMG activity of the knee flexor muscles. The exosuit has been developed with a novel soft fabric actuator and novel 3D printed adjustable braces to attach the actuator aligned with the knee. A torque analytical model has been derived and validate experimentally to characterize and predict the torque output of the actuator. In addition to that, the actuator’s deflation and inflation time has been experimentally characterized and a controller has been implemented and the exosuit has been tested on a healthy human subject. It is found that the analytical torque model succeeded to predict the torque output in flexion angle range from 0° to 60° more precisely than analytical models in the literature. Deviations existed beyond 60° might have happened because some factors like fabric extensibility and actuator’s bending behavior. After human testing, results showed that, for the human subject tested, the exosuit gave the best performance when the controller was tuned to inflate at 31.9 % of the gait cycle. At this inflation timing, the biceps femoris, the semitendinosus and the vastus lateralis muscles showed average electromyography (EMG) reduction of - 32.02 %, - 23.05 % and - 2.85 % respectively. Finally, it is concluded that the developed exosuit may assist the knee flexion of more diverse healthy human subjects and it may potentially be used in the future in human performance augmentation and rehabilitation of people with disabilities.
ContributorsHasan, Ibrahim Mohammed Ibrahim (Author) / Zhang, Wenlong (Thesis advisor) / Aukes, Daniel (Committee member) / McDaniel, Troy (Committee member) / Arizona State University (Publisher)
Created2021
Description
In this thesis, the applications of deep learning in the analysis, detection and classification of medical imaging datasets were studied, with a focus on datasets having a limited sample size. A combined machine learning-deep learning model was designed to classify one small dataset, prostate cancer provided by Mayo Clinic, Arizona. Deep learning model was implemented to extract imaging features followed by machine learning classifier for prostate cancer diagnosis. The results were compared against models trained on texture-based features, namely gray level co-occurrence matrix (GLCM) and Gabor. Some of the challenges of performing diagnosis on medical imaging datasets with limited sample sizes, have been identified. Lastly, a set of future works have been proposed. Keywords: Deep learning, radiology, transfer learning, convolutional neural network.
ContributorsSarkar, Suryadipto (Author) / Wu, Teresa (Thesis advisor) / Papandreou-Suppappola, Antonia (Committee member) / Silva, Alvin (Committee member) / Arizona State University (Publisher)
Created2021
Description
Self-Driving cars are a long-lasting ambition for many AI scientists and engineers. In the last decade alone, many self-driving cars like Google Waymo, Tesla Autopilot, Uber, etc. have been roaming the streets of many cities. As a rapidly expanding field, researchers all over the world are attempting to develop more safe and efficient AI agents that can navigate through our cities. However, driving is a very complex task to master even for a human, let alone the challenges in developing robots to do the same. It requires attention and inputs from the surroundings of the car, and it is nearly impossible for us to program all the possible factors affecting this complex task. As a solution, imitation learning was introduced, wherein the agents learn a policy, mapping the observations to the actions through demonstrations given by humans. Through imitation learning, one could easily teach self-driving cars the expected behavior in many scenarios. Despite their autonomous nature, it is undeniable that humans play a vital role in the development and execution of safe and trustworthy self-driving cars and hence form the strongest link in this application of Human-Robot Interaction. Several approaches were taken to incorporate this link between humans and self-driving cars, one of which involves the communication of human's navigational instruction to self-driving cars. The communicative channel provides humans with control over the agent’s decisions as well as the ability to guide them in real-time. In this work, the abilities of imitation learning in creating a self-driving agent that can follow natural language instructions given by humans based on environmental objects’ descriptions were explored. The proposed model architecture is capable of handling latent temporal context in these instructions thus making the agent capable of taking multiple decisions along its course. The work shows promising results that push the boundaries of natural language instructions and their complexities in navigating self-driving cars through towns.
ContributorsMoudhgalya, Nithish B (Author) / Amor, Hani Ben (Thesis advisor) / Baral, Chitta (Committee member) / Yang, Yezhou (Committee member) / Zhang, Wenlong (Committee member) / Arizona State University (Publisher)
Created2021
Description
In a pursuit-evasion setup where one group of agents tracks down another adversarial group, vision-based algorithms have been known to make use of techniques such as Linear Dynamic Estimation to determine the probable future location of an evader in a given environment. This helps a pursuer attain an edge over the evader that has conventionally benefited from the uncertainty of the pursuit. The pursuer can utilize this knowledge to enable a faster capture of the evader, as opposed to a pursuer that only knows the evader's current location. Inspired by the function of dorsal anterior cingulate cortex (dACC) neurons in natural predators, the use of a predictive model that is built using an encoder-decoder Long Short-Term Memory (LSTM) Network and can produce a more accurate estimate of the evader's future location is proposed. This enables an even quicker capture of a target when compared to previously used filtering-based methods. The effectiveness of the approach is evaluated by setting up these agents in an environment based in the Modular Open Robots Simulation Engine (MORSE). Cross-domain adaptability of the method, without the explicit need to retrain the prediction model is demonstrated by evaluating it in another domain.
ContributorsGodbole, Sumedh (Author) / Yang, Yezhou (Thesis advisor) / Srivastava, Siddharth (Committee member) / Zhang, Wenlong (Committee member) / Arizona State University (Publisher)
Created2021
Description
Touch plays a vital role in maintaining human relationships through social andemotional communications. This research proposes a multi-modal haptic display
capable of generating vibrotactile and thermal haptic signals individually and simultaneously.
The main objective for creating this device is to explore the importance
of touch in social communication, which is absent in traditional communication
modes like a phone call or a video call. By studying how humans interpret
haptically generated messages, this research aims to create a new communication
channel for humans. This novel device will be worn on the user's forearm and has
a broad scope of applications such as navigation, social interactions, notifications,
health care, and education. The research methods include testing patterns in the
vibro-thermal modality while noting its realizability and accuracy. Different patterns
can be controlled and generated through an Android application connected to
the proposed device via Bluetooth. Experimental results indicate that the patterns
SINGLE TAP and HOLD/SQUEEZE were easily identifiable and more relatable to
social interactions. In contrast, other patterns like UP-DOWN, DOWN-UP, LEFTRIGHT,
LEFT-RIGHT, LEFT-DIAGONAL, and RIGHT-DIAGONAL were less
identifiable and less relatable to social interactions. Finally, design modifications
are required if complex social patterns are needed to be displayed on the forearm.
ContributorsGharat, Shubham Shriniwas (Author) / McDaniel, Troy (Thesis advisor) / Redkar, Sangram (Thesis advisor) / Zhang, Wenlong (Committee member) / Arizona State University (Publisher)
Created2021
Description
Asymmetry of bilateral mammographic tissue density and patterns is a potentially strong indicator of having or developing breast abnormalities or early cancers. The purpose of this study is to design and test the global asymmetry features from bilateral mammograms to predict the near-term risk of women developing detectable high risk breast lesions or cancer in the next sequential screening mammography examination. The image dataset includes mammograms acquired from 90 women who underwent routine screening examinations, all interpreted as negative and not recalled by the radiologists during the original screening procedures. A computerized breast cancer risk analysis scheme using four image processing modules, including image preprocessing, suspicious region segmentation, image feature extraction, and classification was designed to detect and compute image feature asymmetry between the left and right breasts imaged on the mammograms. The highest computed area under curve (AUC) is 0.754 ± 0.024 when applying the new computerized aided diagnosis (CAD) scheme to our testing dataset. The positive predictive value and the negative predictive value were 0.58 and 0.80, respectively.
ContributorsSun, Wenqing (Author) / Zheng, Bin (Author) / Lure, Fleming (Author) / Wu, Teresa (Author) / Zhang, Jianying (Author) / Wang, Benjamin Y. (Author) / Saltzstein, Edward C. (Author) / Qian, Wei (Author) / Ira A. Fulton Schools of Engineering (Contributor)
Created2014-07-01
Description
Buildings consume nearly 50% of the total energy in the United States, which drives the need to develop high-fidelity models for building energy systems. Extensive methods and techniques have been developed, studied, and applied to building energy simulation and forecasting, while most of work have focused on developing dedicated modeling approach for generic buildings. In this study, an integrated computationally efficient and high-fidelity building energy modeling framework is proposed, with the concentration on developing a generalized modeling approach for various types of buildings. First, a number of data-driven simulation models are reviewed and assessed on various types of computationally expensive simulation problems. Motivated by the conclusion that no model outperforms others if amortized over diverse problems, a meta-learning based recommendation system for data-driven simulation modeling is proposed. To test the feasibility of the proposed framework on the building energy system, an extended application of the recommendation system for short-term building energy forecasting is deployed on various buildings. Finally, Kalman filter-based data fusion technique is incorporated into the building recommendation system for on-line energy forecasting. Data fusion enables model calibration to update the state estimation in real-time, which filters out the noise and renders more accurate energy forecast. The framework is composed of two modules: off-line model recommendation module and on-line model calibration module. Specifically, the off-line model recommendation module includes 6 widely used data-driven simulation models, which are ranked by meta-learning recommendation system for off-line energy modeling on a given building scenario. Only a selective set of building physical and operational characteristic features is needed to complete the recommendation task. The on-line calibration module effectively addresses system uncertainties, where data fusion on off-line model is applied based on system identification and Kalman filtering methods. The developed data-driven modeling framework is validated on various genres of buildings, and the experimental results demonstrate desired performance on building energy forecasting in terms of accuracy and computational efficiency. The framework could be easily implemented into building energy model predictive control (MPC), demand response (DR) analysis and real-time operation decision support systems.
ContributorsCui, Can (Author) / Wu, Teresa (Thesis advisor) / Weir, Jeffery D. (Thesis advisor) / Li, Jing (Committee member) / Fowler, John (Committee member) / Hu, Mengqi (Committee member) / Arizona State University (Publisher)
Created2016
Description
The researchers build a drone with a grasping mechanism to wrap around branches to perch. The design process and methodology are discussed along with the software and hardware configuration. The researchers explain the influences on the design and the possibilities for what it could inspire.
ContributorsGoldenberg, Edward Bradley (Co-author) / Macias, Jose Carlos (Co-author) / Downey, Matthew (Co-author) / Zhang, Wenlong (Thesis director) / Aukes, Daniel M. (Committee member) / Engineering Programs (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
Description
Background: Genetic profiling represents the future of neuro-oncology but suffers from inadequate biopsies in heterogeneous tumors like Glioblastoma (GBM). Contrast-enhanced MRI (CE-MRI) targets enhancing core (ENH) but yields adequate tumor in only ~60% of cases. Further, CE-MRI poorly localizes infiltrative tumor within surrounding non-enhancing parenchyma, or brain-around-tumor (BAT), despite the importance of characterizing this tumor segment, which universally recurs. In this study, we use multiple texture analysis and machine learning (ML) algorithms to analyze multi-parametric MRI, and produce new images indicating tumor-rich targets in GBM.
Methods: We recruited primary GBM patients undergoing image-guided biopsies and acquired pre-operative MRI: CE-MRI, Dynamic-Susceptibility-weighted-Contrast-enhanced-MRI, and Diffusion Tensor Imaging. Following image coregistration and region of interest placement at biopsy locations, we compared MRI metrics and regional texture with histologic diagnoses of high- vs low-tumor content (≥80% vs <80% tumor nuclei) for corresponding samples. In a training set, we used three texture analysis algorithms and three ML methods to identify MRI-texture features that optimized model accuracy to distinguish tumor content. We confirmed model accuracy in a separate validation set.
Results: We collected 82 biopsies from 18 GBMs throughout ENH and BAT. The MRI-based model achieved 85% cross-validated accuracy to diagnose high- vs low-tumor in the training set (60 biopsies, 11 patients). The model achieved 81.8% accuracy in the validation set (22 biopsies, 7 patients).
Conclusion: Multi-parametric MRI and texture analysis can help characterize and visualize GBM’s spatial histologic heterogeneity to identify regional tumor-rich biopsy targets.
ContributorsHu, Leland S. (Author) / Ning, Shuluo (Author) / Eschbacher, Jennifer M. (Author) / Gaw, Nathan (Author) / Dueck, Amylou C. (Author) / Smith, Kris A. (Author) / Nakaji, Peter (Author) / Plasencia, Jonathan (Author) / Ranjbar, Sara (Author) / Price, Stephen J. (Author) / Tran, Nhan (Author) / Loftus, Joseph (Author) / Jenkins, Robert (Author) / O'Neill, Brian P. (Author) / Elmquist, William (Author) / Baxter, Leslie C. (Author) / Gao, Fei (Author) / Frakes, David (Author) / Karis, John P. (Author) / Zwart, Christine (Author) / Swanson, Kristin R. (Author) / Sarkaria, Jann (Author) / Wu, Teresa (Author) / Mitchell, J. Ross (Author) / Li, Jing (Author) / Ira A. Fulton Schools of Engineering (Contributor)
Created2015-11-24