Matching Items (510)
Description
The Paradise Valley Family Resource Center (PVFRC) is a not for profit, community based organization funded by First Things First and a part of the Paradise Valley Unified School District (PVUSD) in Phoenix, Arizona. The mission of this organization is to connect and strengthen families with children from birth to five years old in the Phoenix valley. The PVFRC longed to be more cognizant of what the needs of the community they serve are, and how they, as an organization, can administer programs of value to the community. Hence, the PVFRC entered a partnership with the Community Action Research Experiences (CARE) program at Arizona State University to develop a research proposal to improve their effectiveness and efficiency at achieving their mission. The purpose of this research project was to identify and evaluate the needs of the families with children ages birth to five within the community, to improve upon existing programs and services or to implement new programs, and to discover more effective modes of awareness and advertisement to the community about the programs and services the PVFRC provides. The main research questions of the experiment included asking participants about what programs and services they need, wish, or want to exist at the PVFRC, what barriers or gaps they see or experience regarding attending the PVFRC, how did participants learn about the PVFRC, and what are the best ways to contact families in their community. The methods of the research included conducting focus group interviews with families who utilize the programs and services at the PVFRC and with early childhood professionals in the Paradise Valley Unified School District (PVUSD), which included social workers and preschool teachers. A total of 25 participants were interviewed (10 families, 6 social workers, and 9 preschool teachers) and responses from the interviews were coded by the researcher. The results of the research was that the PVFRC is meeting many needs and current families are satisfied, participants desire some changes to current programs and services, and the best modes of advertisement and awareness were "word of mouth" and the internet. It was recommended that in order to better achieve their mission, it is advised that the PVFRC make appropriate changes to programs and services as suggested by the participants, connect with mom's or parents groups in the community, collaborate with preschool teachers on the front line, and increase their online presence through the use of social media and their website.
ContributorsHoran, Mary Jensen (Author) / Foster, Stacie (Thesis director) / Brougham, Jennifer (Committee member) / Dumka, Larry (Committee member) / T. Denny Sanford School of Social and Family Dynamics (Contributor) / School of Molecular Sciences (Contributor) / School for the Science of Health Care Delivery (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
Isotopic analyses of archaeological and modern materials are commonly used to reconstruct diet, climate, and habitat. This study analyzes 15 camelid samples from three sites (two archaeological, one modern) in South America to determine their carbon and nitrogen isotopic values to further explore the relationship between stable isotopes and environments. Camelid individuals in the modern site of Cuenca, Ecuador had a diet of almost entirely C3 vegetation, while those in Chen Chen, Peru had slightly higher values, still consistent with C3 plants. Those in the higher altitude site of Pumapunku, Bolivia had higher δ13C values than expected, indicating they may have been foddered with a mixed diet. These isotopic data indicate that vegetation, and therefore herbivore diets, are influenced by altitude. Additionally, it was found that a positive linear relationship exists between δ15N values and aridity of a site. Results indicate that aspects of the environment such as aridity are reflected in isotopic signatures. These results contribute to the increasing amount of data on isotopic variation in South American camelids, both modern and archaeological.
ContributorsSpencer, Katherine Clare (Author) / Knudson, Kelly (Thesis director) / Reed, Kaye (Committee member) / School of Human Evolution and Social Change (Contributor) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
With a quantum efficiency of nearly 100%, the electron transfer process that occurs within the reaction center protein of the photosynthetic bacteria Rhodobacter (Rh.) sphaeroides is a paragon for understanding the complexities, intricacies, and overall systemization of energy conversion and storage in natural systems. To better understand the way in which photons of light are captured, converted into chemically useful forms, and stored for biological use, an investigation into the reaction center protein, specifically into its cascade of cofactors, was undertaken. The purpose of this experimentation was to advance our knowledge and understanding of how differing protein environments and variant cofactors affect the spectroscopic aspects of and electron transfer kinetics within the reaction of Rh. sphaeroides. The native quinone, ubiquinone, was extracted from its pocket within the reaction center protein and replaced by non-native quinones having different reduction/oxidation potentials. It was determined that, of the two non-native quinones tested—1,2-naphthaquinone and 9,10- anthraquinone—the substitution of the anthraquinone (lower redox potential) resulted in an increased rate of recombination from the P+QA- charge-separated state, while the substitution of the napthaquinone (higher redox potential) resulted in a decreased rate of recombination.
ContributorsSussman, Hallie Rebecca (Author) / Woodbury, Neal (Thesis director) / Redding, Kevin (Committee member) / Lin, Su (Committee member) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2015-12
Description
The purpose of the study was to examine the associations of protective (ethic identity, parent-child closeness) and risk (perceived discrimination, parent-child role reversal) factors with mental and behavioral health in 2nd generation Cambodian American (CA) young adults. A total of 66 participants who identified as being 2nd generation CA young adults aged 18-25 years old were recruited to participate in this cross-sectional. Reliable and valid measures were used to assess protective and risk factors and mental (depressive, anxiety, somatic symptoms) and behavioral health outcomes (alcohol and drug use). We used descriptive statistics to describe sample characteristics and study variables and conducted multiple regression analysis to examine the associations of factors with each of the 5 health outcomes. The findings suggested that peer discrimination was positively and significantly associated with depressive (β = 0.42, p = 0.023; R2 = 0.397) and somatic symptoms (β = 0.63, p = 0.000, R2 = 0.554). Father role-reversal was also found to be negatively and significantly associated with predicting CA young adults’ anxiety symptoms (β = -0.32, p = 0.005, R2 = 0.456).
Majority of the CA young adults have perceived racial/ethnic discrimination in the community. Furthermore, perceived discrimination has been positively associated with their depressive and somatic symptoms, suggesting a need to address racial/ethnic discrimination issues to promote positive mental health in this population. It is important for school/work personnel and healthcare providers to assess CA young adults’ discrimination experiences, and have the sufficient resources (e.g., education, support groups) to prevent negative consequences associated with discrimination.
Majority of the CA young adults have perceived racial/ethnic discrimination in the community. Furthermore, perceived discrimination has been positively associated with their depressive and somatic symptoms, suggesting a need to address racial/ethnic discrimination issues to promote positive mental health in this population. It is important for school/work personnel and healthcare providers to assess CA young adults’ discrimination experiences, and have the sufficient resources (e.g., education, support groups) to prevent negative consequences associated with discrimination.
ContributorsOu, Jason Heng (Author) / Chen, Angela Chia-Chia (Thesis director) / Sangalang, Cindy (Committee member) / Miroballi, Barbara (Committee member) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2015-12
Description
This study was conducted to observe the effects of vitamin C supplementation upon the expression of sICAM-1 in asthmatic subject. Two groups were created, each with a sample size of 4 subjects. One group was the vitamin C group (VC) and the other was the placebo group (PL). The study was analyzed through observing concentrations of biomolecules present within samples of blood plasma and nasal lavages. These included vitamin C, sICAM-1 expression, and histamine. The following P-values calculated from the data collected from this study. The plasma vitamin C screening was p=0.3, and after 18 days of supplementation, p=0.03. For Nasal ICAM p=0.5 at Day 0, p=0.4 at Day 4, and p=0.9 at Day 18. For the Histamine samples p=0.9 at Day 0 and p=0.9 at Day 18. The following P-values calculated from the data collected from both studies. The plasma vitamin C screening was p=0.8, and after 18 days of supplementation, p=0.03. The change of vitamin C at the end of this study and the combined data both had a P-value that was calculated to be lower than 0.05, which meant that this change was significant because it was due to the intervention and not chance. For Nasal ICAM samples p=0.7 at Day 0, p=0.7 at Day 4, and p=1 at Day 18. For the Histamine p=0.7 at Day 0 and p=0.9 at Day 18. This study carries various implications although the study data was unable to show much significance. This was the second study to test this, and as more research is done, and the sample size grows, one will be able to observe whether this really is the mechanism through which vitamin C plays a role in immunological functions.
ContributorsKapadia, Chirag Vinay (Author) / Johnston, Carol (Thesis director) / LaBaer, Joshua (Committee member) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2015-12
Description
Methods of second language (L2) teaching should involve exposure to authentic forms to facilitate the development of proficiency and fluency. Exposure to authentic forms is important because prior research has shown that natural language discourse uses mostly prefabricated linguistic units (prefabs-formulaic language) that aid in developing linguistic competence and fluency; this occurs because learners' cognitive load is decreased when they are able to retrieve prefabricated wholes from their L2 repertoire as they produce L2 discourse (Erman & Warren, 2000). An effective method of acquiring prefabricated constructions as single units of meaning or structure is repetition of exposure to whole collocations (words that occur together in fixed phrases), since attention will shift from the individual constituents of the phrase to the unit as a whole as the meaning-bearing stored form (Bybee et al., 2006). Authentic materials (materials produced by native speakers for native speakers) contain a substantial number of prefabricated meaning units that are characteristic of native-speaker produced natural language. Compared to traditional L2 classroom approaches, authentic materials are more likely to engage learners due to the range of options available for learner interest; there is a psychological benefit for students who can be certain that their progress with authentic materials is tantamount to progress outside the classroom setting (Berardo, 2006; Ugalde, 2008). The efficacy of exposure to authentic forms can also be explained by virtue of the fact that it promotes incidental acquisition, which is the primary manner by which language is learned (Ellis & Wulff, 2015); it does so through facilitating implicit pattern recognition of exemplar structures. The research concludes with a discussion of why pedagogical approaches should seek to incorporate formulaic language for learners to achieve fluency.
ContributorsGuerithault, Nicolas Owen (Author) / Lafford, Barbara (Thesis director) / Martinez, Jacqueline (Committee member) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
The Downtown ASU campus Bio 201 and 202 anatomy labs are planning on revising the method in which students are presented and evaluated on lab material for the Fall 2016 semester. The goal of this thesis project was to analyze the methods used in previous semesters in order to determine which method, if any, proved to be the most effective means of evaluation for the students. The general setup of the anatomy labs is that the students come to lab, receive that week's instruction, and then are quizzed on that week's material at the beginning of their next lab. Then roughly every five new segments there is a practical covering the cumulative information from the last five segments. Therefore it is imperative to analyze the current and previous methods of evaluation in order to find which one has the strongest correlation with an individual's quiz performance and their practical grade. Since the Fall 2014 semester three different quiz types have been used in lab while the practical has remained the same. The three different types of quizzes are written, turning point, and no quiz; in order to determine which method was most effective overall practical averages for each student was compared to their corresponding quiz average. This data was put into Excel and used to generate a graph in order to determine the r-squared values to determine which had the strongest correlation. The results showed that no matter what quiz type was used there was no statistically significant correlation between quiz performance and practical performance; in fact practical averages were nearly identical between semesters for Bio 201 and 202. However, visual analysis of the graph demonstrated that certain quiz methods did seem to be more effective than others. For Bio 201 it seemed that written quizzes were the most effective means of evaluation, while in Bio 202 the turning point quizzes were best.
ContributorsOlson, Zachary G (Author) / Kingsbury, Jeffrey (Thesis director) / Legere, Jenny (Committee member) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
DescriptionThis creative project provides documentation and an exploration of my interactions with individuals encountered while hitchhiking up the west coast.
ContributorsGerber, Evan Howard (Author) / Kashiwagi, Dean (Thesis director) / Kashiwagi, Jacob (Committee member) / W. P. Carey School of Business (Contributor) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
Many stressors today are psychological rather than physical and are influenced by the brain's perception of the stressor. The peripartum period is a particularly volatile time that is susceptible to new and stronger stressors. This current study investigates the relationship between self-reported perceived stress levels and physiological cortisol reactivity levels in new mothers at the 12-week postpartum time point. In addition, it examines the relationship between the mother and infants' physiological cortisol reactivity levels at 12-weeks postpartum. This current study is part of a longitudinal study and assessed these two correlations for 181 mother-infant dyads from a low income Mexican American population. The self-reported stress levels were assessed using the 4-item Perceived Stress Scale (PSS) and the cortisol reactivity data was gathered using four salivary cortisol samples taken from both mother and infant surrounding 5 interaction tasks and analyzed using Area Under the Curve with respect to ground (AUCg). Unexpectedly, the results found no correlation between perceived and physiological stress levels in the mothers, with a Pearson correlation of 0.114 and a p-value of 0.129. However, there was a positive correlation between mother and infant cortisol reactivity, with a correlation of 0.632 and a p-value less than 0.0001. This early postpartum period plays a significant role in developing HPA axis regulation for infants and developing productive mother-infant interactions. The physiological and psychological risks of chronically elevated stress for both mothers and children were addressed in this study as well, with implications for means to address and mitigate potential cortisol dysregulation.
ContributorsRegan, Emily Nicole (Author) / Washo-Krupps, Delon (Thesis director) / Crnic, Keith (Committee member) / Hanna, Mariam (Committee member) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
A single splice site mutation in the mitochondrial methionyl-tRNA formyltransferase (MTFMT) gene is described in three patients with mitochondrial disease from two unrelated families. Nuclear-encoded MTFMT localized to the mitochondria is responsible for the formylation of Met-tRNAMet necessary for the initiation of translation in the mitochondria. This mutation has been associated with mitochondrial disease (oxidative phosphorylation deficiencies due to a decreased expression of MTFMT), Leigh syndrome, and developmental delay. However, there is significant phenotypic variation between patients, which is not uncommon in mitochondrial disease. Though the variation was not clearly elucidated through analysis of gene expression, this data supported two potential gene modifiers as well as proposed an alternative energy producing pathway in the cell—glutamine metabolism. This nonsynonymous mutation at site c.626C>T generates a splicing suppressor in the coding region on exon 4 resulting exon skipping in almost all transcripts in homozygotes during splicing. It is hypothesized that antisense oligotherapy will be effective in rescuing this mutation by inhibiting the splice silencer and promoting exon inclusion as well as an increased expression of MTFMT protein in affected patients. Patient fibroblast cells were treated with MTFMT Oligo 3, which was shown to be promising in previous experiments. Real-Time qPCR was used to measure mRNA expression showing a significant up-regulation of wild-type MTFMT with treatment. In order to test whether this therapy increases mitochondrial function as well, three mitochondrial functional assays measuring superoxide species in the mitochondria, the mitochondrial membrane potential, and calcium uptake in the mitochondria were tested for optimization of results. Success has been shown in the measurement of superoxide species and mitochondrial membrane potential in patient cells without treatment. Oligotherapy will hopefully be considered as a viable therapeutic option in the future as further testing is conducted and perfected.
ContributorsMoskowitz, Abby Mae (Author) / Huentelman, Matt (Thesis director) / Schrauwen, Isabelle (Committee member) / Rangasamy, Sampath (Committee member) / School of Human Evolution and Social Change (Contributor) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05