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This thesis outlines the development of a vector retrieval technique, based on data assimilation, for a coherent Doppler LIDAR (Light Detection and Ranging). A detailed analysis of the Optimal Interpolation (OI) technique for vector retrieval is presented. Through several modifications to the OI technique, it is shown that the modified

This thesis outlines the development of a vector retrieval technique, based on data assimilation, for a coherent Doppler LIDAR (Light Detection and Ranging). A detailed analysis of the Optimal Interpolation (OI) technique for vector retrieval is presented. Through several modifications to the OI technique, it is shown that the modified technique results in significant improvement in velocity retrieval accuracy. These modifications include changes to innovation covariance portioning, covariance binning, and analysis increment calculation. It is observed that the modified technique is able to make retrievals with better accuracy, preserves local information better, and compares well with tower measurements. In order to study the error of representativeness and vector retrieval error, a lidar simulator was constructed. Using the lidar simulator a thorough sensitivity analysis of the lidar measurement process and vector retrieval is carried out. The error of representativeness as a function of scales of motion and sensitivity of vector retrieval to look angle is quantified. Using the modified OI technique, study of nocturnal flow in Owens' Valley, CA was carried out to identify and understand uncharacteristic events on the night of March 27th 2006. Observations from 1030 UTC to 1230 UTC (0230 hr local time to 0430 hr local time) on March 27 2006 are presented. Lidar observations show complex and uncharacteristic flows such as sudden bursts of westerly cross-valley wind mixing with the dominant up-valley wind. Model results from Coupled Ocean/Atmosphere Mesoscale Prediction System (COAMPS®) and other in-situ instrumentations are used to corroborate and complement these observations. The modified OI technique is used to identify uncharacteristic and extreme flow events at a wind development site. Estimates of turbulence and shear from this technique are compared to tower measurements. A formulation for equivalent wind speed in the presence of variations in wind speed and direction, combined with shear is developed and used to determine wind energy content in presence of turbulence.
ContributorsChoukulkar, Aditya (Author) / Calhoun, Ronald (Thesis advisor) / Mahalov, Alex (Committee member) / Kostelich, Eric (Committee member) / Huang, Huei-Ping (Committee member) / Phelan, Patrick (Committee member) / Arizona State University (Publisher)
Created2013
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Description
Droughts are a common phenomenon of the arid South-west USA climate. Despite water limitations, the region has been substantially transformed by agriculture and urbanization. The water requirements to support these human activities along with the projected increase in droughts intensity and frequency challenge long term sustainability and water security, thus

Droughts are a common phenomenon of the arid South-west USA climate. Despite water limitations, the region has been substantially transformed by agriculture and urbanization. The water requirements to support these human activities along with the projected increase in droughts intensity and frequency challenge long term sustainability and water security, thus the need to spatially and temporally characterize land use/land cover response to drought and quantify water consumption is crucial. This dissertation evaluates changes in `undisturbed' desert vegetation in response to water availability to characterize climate-driven variability. A new model coupling phenology and spectral unmixing was applied to Landsat time series (1987-2010) in order to derive fractional cover (FC) maps of annuals, perennials, and evergreen vegetation. Results show that annuals FC is controlled by short term water availability and antecedent soil moisture. Perennials FC follow wet-dry multi-year regime shifts, while evergreen is completely decoupled from short term changes in water availability. Trend analysis suggests that different processes operate at the local scale. Regionally, evergreen cover increased while perennials and annuals cover decreased. Subsequently, urban land cover was compared with its surrounding desert. A distinct signal of rain use efficiency and aridity index was documented from remote sensing and a soil-water-balance model. It was estimated that a total of 295 mm of water input is needed to sustain current greenness. Finally, an energy balance model was developed to spatio-temporally estimate evapotranspiration (ET) as a proxy for water consumption, and evaluate land use/land cover types in response to drought. Agricultural fields show an average ET of 9.3 mm/day with no significant difference between drought and wet conditions, implying similar level of water usage regardless of climatic conditions. Xeric neighborhoods show significant variability between dry and wet conditions, while mesic neighborhoods retain high ET of 400-500 mm during drought due to irrigation. Considering the potentially limited water availability, land use/land cover changes due to population increases, and the threat of a warming and drying climate, maintaining large water-consuming, irrigated landscapes challenges sustainable practices of water conservation and the need to provide amenities of this desert area for enhancing quality of life.
ContributorsKaplan, Shai (Author) / Myint, Soe Win (Thesis advisor) / Brazel, Anthony J. (Committee member) / Georgescu, Matei (Committee member) / Arizona State University (Publisher)
Created2014
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Description
A general continuum model for simulating the flow of ions in the salt baths that surround and fill excitable neurons is developed and presented. The ion densities and electric potential are computed using the drift-diffusion equations. In addition, a detailed model is given for handling the electrical dynamics on interior

A general continuum model for simulating the flow of ions in the salt baths that surround and fill excitable neurons is developed and presented. The ion densities and electric potential are computed using the drift-diffusion equations. In addition, a detailed model is given for handling the electrical dynamics on interior membrane boundaries, including a model for ion channels in the membranes that facilitate the transfer of ions in and out of cells. The model is applied to the triad synapse found in the outer plexiform layer of the retina in most species. Experimental evidence suggests the existence of a negative feedback pathway between horizontal cells and cone photoreceptors that modulates the flow of calcium ions into the synaptic terminals of cones. However, the underlying mechanism for this feedback is controversial and there are currently three competing hypotheses: the ephaptic hypothesis, the pH hypothesis and the GABA hypothesis. The goal of this work is to test some features of the ephaptic hypothesis using detailed simulations that employ rigorous numerical methods. The model is first applied in a simple rectangular geometry to demonstrate the effects of feedback for different extracellular gap widths. The model is then applied to a more complex and realistic geometry to demonstrate the existence of strictly electrical feedback, as predicted by the ephaptic hypothesis. Lastly, the effects of electrical feedback in regards to the behavior of the bipolar cell membrane potential is explored. Figures for the ion densities and electric potential are presented to verify key features of the model. The computed steady state IV curves for several cases are presented, which can be compared to experimental data. The results provide convincing evidence in favor of the ephaptic hypothesis since the existence of feedback that is strictly electrical in nature is shown, without any dependence on pH effects or chemical transmitters.
ContributorsJones, Jeremiah (Author) / Gardner, Carl (Committee member) / Baer, Steven (Committee member) / Crook, Sharon (Committee member) / Kostelich, Eric (Committee member) / Ringhofer, Christian (Committee member) / Arizona State University (Publisher)
Created2013
Description
It is possible in a properly controlled environment, such as industrial metrology, to make significant headway into the non-industrial constraints on image-based position measurement using the techniques of image registration and achieve repeatable feature measurements on the order of 0.3% of a pixel, or about an order of magnitude improvement

It is possible in a properly controlled environment, such as industrial metrology, to make significant headway into the non-industrial constraints on image-based position measurement using the techniques of image registration and achieve repeatable feature measurements on the order of 0.3% of a pixel, or about an order of magnitude improvement on conventional real-world performance. These measurements are then used as inputs for a model optimal, model agnostic, smoothing for calibration of a laser scribe and online tracking of velocimeter using video input. Using appropriate smooth interpolation to increase effective sample density can reduce uncertainty and improve estimates. Use of the proper negative offset of the template function has the result of creating a convolution with higher local curvature than either template of target function which allows improved center-finding. Using the Akaike Information Criterion with a smoothing spline function it is possible to perform a model-optimal smooth on scalar measurements without knowing the underlying model and to determine the function describing the uncertainty in that optimal smooth. An example of empiric derivation of the parameters for a rudimentary Kalman Filter from this is then provided, and tested. Using the techniques of Exploratory Data Analysis and the "Formulize" genetic algorithm tool to convert the spline models into more accessible analytic forms resulted in stable, properly generalized, KF with performance and simplicity that exceeds "textbook" implementations thereof. Validation of the measurement includes that, in analytic case, it led to arbitrary precision in measurement of feature; in reasonable test case using the methods proposed, a reasonable and consistent maximum error of around 0.3% the length of a pixel was achieved and in practice using pixels that were 700nm in size feature position was located to within ± 2 nm. Robust applicability is demonstrated by the measurement of indicator position for a King model 2-32-G-042 rotameter.
ContributorsMunroe, Michael R (Author) / Phelan, Patrick (Thesis advisor) / Kostelich, Eric (Committee member) / Mahalov, Alex (Committee member) / Arizona State University (Publisher)
Created2012
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Description
Climate change is one of the most pressing issues affecting the world today. One of the impacts of climate change is on the transmission of mosquito-borne diseases (MBDs), such as West Nile Virus (WNV). Climate is known to influence vector and host demography as well as MBD transmission. This dissertation

Climate change is one of the most pressing issues affecting the world today. One of the impacts of climate change is on the transmission of mosquito-borne diseases (MBDs), such as West Nile Virus (WNV). Climate is known to influence vector and host demography as well as MBD transmission. This dissertation addresses the questions of how vector and host demography impact WNV dynamics, and how expected and likely climate change scenarios will affect demographic and epidemiological processes of WNV transmission. First, a data fusion method is developed that connects non-autonomous logistic model parameters to mosquito time series data. This method captures the inter-annual and intra-seasonal variation of mosquito populations within a geographical location. Next, a three-population WNV model between mosquito vectors, bird hosts, and human hosts with infection-age structure for the vector and bird host populations is introduced. A sensitivity analysis uncovers which parameters have the most influence on WNV outbreaks. Finally, the WNV model is extended to include the non-autonomous population model and temperature-dependent processes. Model parameterization using historical temperature and human WNV case data from the Greater Toronto Area (GTA) is conducted. Parameter fitting results are then used to analyze possible future WNV dynamics under two climate change scenarios. These results suggest that WNV risk for the GTA will substantially increase as temperature increases from climate change, even under the most conservative assumptions. This demonstrates the importance of ensuring that the warming of the planet is limited as much as possible.
ContributorsMancuso, Marina (Author) / Milner, Fabio A (Thesis advisor) / Kuang, Yang (Committee member) / Kostelich, Eric (Committee member) / Eikenberry, Steffen (Committee member) / Manore, Carrie (Committee member) / Arizona State University (Publisher)
Created2023
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Description
This work presents a thorough analysis of reconstruction of global wave fields (governed by the inhomogeneous wave equation and the Maxwell vector wave equation) from sensor time series data of the wave field. Three major problems are considered. First, an analysis of circumstances under which wave fields can be fully

This work presents a thorough analysis of reconstruction of global wave fields (governed by the inhomogeneous wave equation and the Maxwell vector wave equation) from sensor time series data of the wave field. Three major problems are considered. First, an analysis of circumstances under which wave fields can be fully reconstructed from a network of fixed-location sensors is presented. It is proven that, in many cases, wave fields can be fully reconstructed from a single sensor, but that such reconstructions can be sensitive to small perturbations in sensor placement. Generally, multiple sensors are necessary. The next problem considered is how to obtain a global approximation of an electromagnetic wave field in the presence of an amplifying noisy current density from sensor time series data. This type of noise, described in terms of a cylindrical Wiener process, creates a nonequilibrium system, derived from Maxwell’s equations, where variance increases with time. In this noisy system, longer observation times do not generally provide more accurate estimates of the field coefficients. The mean squared error of the estimates can be decomposed into a sum of the squared bias and the variance. As the observation time $\tau$ increases, the bias decreases as $\mathcal{O}(1/\tau)$ but the variance increases as $\mathcal{O}(\tau)$. The contrasting time scales imply the existence of an ``optimal'' observing time (the bias-variance tradeoff). An iterative algorithm is developed to construct global approximations of the electric field using the optimal observing times. Lastly, the effect of sensor acceleration is considered. When the sensor location is fixed, measurements of wave fields composed of plane waves are almost periodic and so can be written in terms of a standard Fourier basis. When the sensor is accelerating, the resulting time series is no longer almost periodic. This phenomenon is related to the Doppler effect, where a time transformation must be performed to obtain the frequency and amplitude information from the time series data. To obtain frequency and amplitude information from accelerating sensor time series data in a general inhomogeneous medium, a randomized algorithm is presented. The algorithm is analyzed and example wave fields are reconstructed.
ContributorsBarclay, Bryce Matthew (Author) / Mahalov, Alex (Thesis advisor) / Kostelich, Eric J (Thesis advisor) / Moustaoui, Mohamed (Committee member) / Motsch, Sebastien (Committee member) / Platte, Rodrigo (Committee member) / Arizona State University (Publisher)
Created2023
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Description
This thesis focuses on the turbulent bluff body wakes in incompressible and compressible flows. An incompressible wake flow past an axisymmetric body of revolution at a diameter-based Reynolds number Re=5000 is investigated via a direct numerical simulation. It is followed by the development of a compressible solver using a split-form

This thesis focuses on the turbulent bluff body wakes in incompressible and compressible flows. An incompressible wake flow past an axisymmetric body of revolution at a diameter-based Reynolds number Re=5000 is investigated via a direct numerical simulation. It is followed by the development of a compressible solver using a split-form discontinuous Galerkin spectral element method framework with shock capturing. In the study on incompressible wake flows, three dominant coherent vortical motions are identified in the wake: the vortex shedding motion with the frequency of St=0.27, the bubble pumping motion with St=0.02, and the very-low-frequency (VLF) motion originated in the very near wake of the body with the frequencies St=0.002 and 0.005. The very-low-frequency motion is associated with a slow precession of the wake barycenter. The vortex shedding pattern is demonstrated to follow a reflectional symmetry breaking mode, with the detachment location rotating continuously and making a full circle over one vortex shedding period. The VLF radial motion with St=0.005 originates as m = 1 mode, but later transitions into m = 2 mode in the intermediate wake. Proper orthogonaldecomposition (POD) and dynamic mode decomposition (DMD) are further performed to analyze the spatial structure associated with the dominant coherent motions. Results of the POD and DMD analysis are consistent with the results of the azimuthal Fourier analysis. To extend the current incompressible code to be able to solve compressible flows, a computational methodology is developed using a high-order approximation for the compressible Navier-Stokes equations with discontinuities. The methodology is based on a split discretization framework with a summation-by-part operator. An entropy viscosity method and a subcell finite volume method are implemented to capture discontinuities. The developed high-order split-form with shock-capturing methodology is subject to a series of evaluation on cases from subsonic to hypersonic, from one-dimensional to three dimensional. The Taylor-Green vortex case and the supersonic sphere wake case show the capability to handle three-dimensional turbulent flows without and with the presence of shocks. It is also shown that higher-order approximations yield smaller errors than lower-order approximations, for the same number of total degrees of freedom.
ContributorsZhang, Fengrui (Author) / Peet, Yulia (Thesis advisor) / Kostelich, Eric (Committee member) / Kim, Jeonglae (Committee member) / Hermann, Marcus (Committee member) / Adrian, Ronald (Committee member) / Arizona State University (Publisher)
Created2022
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Description
High-dimensional systems are difficult to model and predict. The underlying mechanisms of such systems are too complex to be fully understood with limited theoretical knowledge and/or physical measurements. Nevertheless, redcued-order models have been widely used to study high-dimensional systems, because they are practical and efficient to develop and implement. Although

High-dimensional systems are difficult to model and predict. The underlying mechanisms of such systems are too complex to be fully understood with limited theoretical knowledge and/or physical measurements. Nevertheless, redcued-order models have been widely used to study high-dimensional systems, because they are practical and efficient to develop and implement. Although model errors (biases) are inevitable for reduced-order models, these models can still be proven useful to develop real-world applications. Evaluation and validation for idealized models are indispensable to serve the mission of developing useful applications. Data assimilation and uncertainty quantification can provide a way to assess the performance of a reduced-order model. Real data and a dynamical model are combined together in a data assimilation framework to generate corrected model forecasts of a system. Uncertainties in model forecasts and observations are also quantified in a data assimilation cycle to provide optimal updates that are representative of the real dynamics. In this research, data assimilation is applied to assess the performance of two reduced-order models. The first model is developed for predicting prostate cancer treatment response under intermittent androgen suppression therapy. A sequential data assimilation scheme, the ensemble Kalman filter (EnKF), is used to quantify uncertainties in model predictions using clinical data of individual patients provided by Vancouver Prostate Center. The second model is developed to study what causes the changes of the state of stratospheric polar vortex. Two data assimilation schemes: EnKF and ES-MDA (ensemble smoother with multiple data assimilation), are used to validate the qualitative properties of the model using ECMWF (European Center for Medium-Range Weather Forecasts) reanalysis data. In both studies, the reduced-order model is able to reproduce the data patterns and provide insights to understand the underlying mechanism. However, significant model errors are also diagnosed for both models from the results of data assimilation schemes, which suggests specific improvements of the reduced-order models.
ContributorsWu, Zhimin (Author) / Kostelich, Eric (Thesis advisor) / Moustaoui, Mohamed (Thesis advisor) / Jones, Chris (Committee member) / Espanol, Malena (Committee member) / Platte, Rodrigo (Committee member) / Arizona State University (Publisher)
Created2021
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Description
Synthetic biology (SB) has become an important field of science focusing on designing and engineering new biological parts and systems, or re-designing existing biological systems for useful purposes. The dramatic growth of SB throughout the past two decades has not only provided us numerous achievements, but also brought us more

Synthetic biology (SB) has become an important field of science focusing on designing and engineering new biological parts and systems, or re-designing existing biological systems for useful purposes. The dramatic growth of SB throughout the past two decades has not only provided us numerous achievements, but also brought us more timely and underexplored problems. In SB's entire history, mathematical modeling has always been an indispensable approach to predict the experimental outcomes, improve experimental design and obtain mechanism-understanding of the biological systems. \textit{Escherichia coli} (\textit{E. coli}) is one of the most important experimental platforms, its growth dynamics is the major research objective in this dissertation. Chapter 2 employs a reaction-diffusion model to predict the \textit{E. coli} colony growth on a semi-solid agar plate under multiple controls. In that chapter, a density-dependent diffusion model with non-monotonic growth to capture the colony's non-linear growth profile is introduced. Findings of the new model to experimental data are compared and contrasted with those from other proposed models. In addition, the cross-sectional profile of the colony are computed and compared with experimental data. \textit{E. coli} colony is also used to perform spatial patterns driven by designed gene circuits. In Chapter 3, a gene circuit (MINPAC) and its corresponding pattern formation results are presented. Specifically, a series of partial differential equation (PDE) models are developed to describe the pattern formation driven by the MINPAC circuit. Model simulations of the patterns based on different experimental conditions and numerical analysis of the models to obtain a deeper understanding of the mechanisms are performed and discussed. Mathematical analysis of the simplified models, including traveling wave analysis and local stability analysis, is also presented and used to explore the control strategies of the pattern formation. The interaction between the gene circuit and the host \textit{E. coli} may be crucial and even greatly affect the experimental outcomes. Chapter 4 focuses on the growth feedback between the circuit and the host cell under different nutrient conditions. Two ordinary differential equation (ODE) models are developed to describe such feedback with nutrient variation. Preliminary results on data fitting using both two models and the model dynamical analysis are included.
ContributorsHe, Changhan (Author) / Kuang, Yang (Thesis advisor) / Wang, Xiao (Committee member) / Kostelich, Eric (Committee member) / Tian, Xiaojun (Committee member) / Gumel, Abba (Committee member) / Arizona State University (Publisher)
Created2021
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Description
In the realm of discrete ill-posed problems, image deblurring is a challenging problem aimed at restoring clear and visually appealing images from their blurred counterparts. Over the years, various numerical techniques have been developed to solve this problem, each offering unique approaches to tackle blurring and noise.This thesis studies multilevel

In the realm of discrete ill-posed problems, image deblurring is a challenging problem aimed at restoring clear and visually appealing images from their blurred counterparts. Over the years, various numerical techniques have been developed to solve this problem, each offering unique approaches to tackle blurring and noise.This thesis studies multilevel methods using Daubechies wavelets and Tikhonov regularization. The Daubechies wavelets are a family of orthogonal wavelets widely used in various fields because of their orthogonality and compact support. They have been widely applied in signal processing, image compression, and other applications. One key aspect of this investigation involves a comprehensive comparative analysis with Krylov methods, well-established iterative methods known for their efficiency and accuracy in solving large-scale inverse problems. The focus is on two well-known Krylov methods, namely hybrid LSQR and hybrid generalized minimal residual method \linebreak(GMRES). By contrasting the multilevel and Krylov methods, the aim is to discern their strengths and limitations, facilitating a deeper understanding of their applicability in diverse image-deblurring scenarios. Other critical comparison factors are the noise level adopted during the deblurring process and the amount of blur. To gauge their robustness and performance under different blurry and noisy conditions, this work explores how each method behaves with different noise levels from mild to severe and different amounts of blur from small to large. Moreover, this thesis combines multilevel and Krylov methods to test a new method for solving inverse problems. This work aims to provide valuable insights into the strengths and weaknesses of these multilevel Krylov methods by shedding light on their efficacy. Ultimately, the findings could have implications across diverse domains, including medical imaging, remote sensing, and multimedia applications, where high-quality and noise-free images are indispensable for accurate analysis and interpretation.
ContributorsAmdouni, Bechir (Author) / Espanol, Malena (Thesis advisor) / Renaut, Rosemary (Committee member) / Platte, Rodrigo (Committee member) / Fricks, John (Committee member) / Moustaoui, Mohamed (Committee member) / Arizona State University (Publisher)
Created2024