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Twilight Sleep was a technique originally developed by physicians in Germany in the early 20th century as a novel way to address parturient women’s fear and aversion to pain endured during labor and childbirth. Using a combination of amnestic and analgesic agents such as scopolamine and morphine to synergistically suppress

Twilight Sleep was a technique originally developed by physicians in Germany in the early 20th century as a novel way to address parturient women’s fear and aversion to pain endured during labor and childbirth. Using a combination of amnestic and analgesic agents such as scopolamine and morphine to synergistically suppress pregnant women’s memories, physicians Carl Gauss and Bernhard Krönig enabled women to give birth free of pain, or more accurately any memories of pain.

Despite widespread use throughout Europe, Twilight Sleep initially experienced less popularity and more resistance in the United States where doctors were wary of the potential health risks that Twilight Sleep brought upon women and infants. Some adverse effects caused by incorrect doses of scopolamine and morphine included hallucinations and uncontrolled thrashing in women and depressed respiration in infants. Thus, Twilight Sleep’s status as a vogue topic in obstetrics during the first half of the 20th century came about due to the work of affluent and educated American women. While lacking formal medical training, a subset of women became experts in the matter of Twilight Sleep by traveling to Germany to experience and investigate Twilight Sleep firsthand then disseminating their findings through published books and articles.

This thesis explores the impact of Twilight Sleep on women and physicians and their perceptions of childbirth. Twilight Sleep empowered women to take on a more active role in shaping the medical care they received rather than accepting that childbirth as a natural event associated with physical and mental trauma and high risk of mortality. For doctors, the debate regarding Twilight Sleep’s safety and efficacy affirmed a ubiquitous notion that childbirth ought to be seen as a pathological rather than natural event. By considering childbirth a medical condition that necessitated treatment, physicians had to evaluate their duties to their patients. In empowering women to be involved in making medical decisions and forcing physicians to balance their medical training with their patients’ needs, Twilight Sleep helped to establishing more reciprocal doctor-patient relationships.
ContributorsTran, Yvette Ho (Author) / Maienschein, Jane (Thesis director) / Hurlbut, Ben (Committee member) / O'Neil, Erica (Committee member) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
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"French Vanilla" is a collection of written narratives drawn from lived experiences which serve as the vehicle storytelling that I use to examine larger themes related to the intersections of race and gender. Themes include: binaries, legitimacy, intersectionality, biracial identity development (border identity construction), whiteness, shame, and crisis. While the

"French Vanilla" is a collection of written narratives drawn from lived experiences which serve as the vehicle storytelling that I use to examine larger themes related to the intersections of race and gender. Themes include: binaries, legitimacy, intersectionality, biracial identity development (border identity construction), whiteness, shame, and crisis. While the narratives are situated within theoretical discourse, the narratives present a representation of the lived experience. These pieces engage members of my family as well as a number of figures, including Rachel Dolezal, President Barack Obama, Alicia Keys, and a stranger on a tram in an airport. My relationship with these people present the grounds for an interrogation of identity. This project asks the question: How does one negotiate biracial identity with herself and others through narrative performance? It engages theories, such as critical race theory, black feminist theory, and standpoint theory, which informed my understanding of the discourse of race and contextualized my commentary on race. These theories present a framework within which to situate my understanding and analysis of race through lived experience. Narrative performance, the formal methodology for this work, provides a structure for the performance itself: the ultimate end product. Note: This work of creative scholarship is rooted in collaboration between three female artist-scholars: Carly Bates, Raji Ganesan, and Allyson Yoder. Working from a common intersectional, feminist framework, we served as artistic co-directors of each other's solo pieces and co-producers of Negotiations, in which we share these pieces in relationship to each other. Thus, Negotiations is not a showcase of three individual works, but rather a conversation among three voices. As collaborators, we have been uncompromising in the pursuit of our own unique inquiries and voices, and each of our works of creative scholarship stand alone. However, we believe that all of the parts are best understood in relationship to each other and to the whole. For this reason, we have chosen to cross-reference our thesis documents: French Vanilla: An Exploration of Biracial Identity Through Narrative Performance by Carly Bates; Deep roots, shared fruits: Emergent creative process and the ecology of solo performance through "Dress in Something Plain and Dark" by Allyson Yoder; and Bhairavi: A Performance-Investigation of Belonging and Dis-Belonging in Diaspora Communities by Raji Ganesan.
ContributorsBates, Carly Christopher (Author) / Davis, Olga Idriss (Thesis director) / de la Garza, Sarah Amira (Committee member) / Dove-Viebahn, Aviva (Committee member) / School of Music (Contributor) / Department of English (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
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Description
My name is Adriana Becerra and I am a student at the Walter Cronkite School of Journalism and Mass Communication at Arizona State University. In hoping to combine my two passions of journalism and film, for my Honors Undergraduate Thesis project I created my own film review website. My website

My name is Adriana Becerra and I am a student at the Walter Cronkite School of Journalism and Mass Communication at Arizona State University. In hoping to combine my two passions of journalism and film, for my Honors Undergraduate Thesis project I created my own film review website. My website is a complete review of the films that were nominated for the 2015 Oscars in the following categories: Best Picture, Animated Feature, Documentary Feature, Foreign Language, and Short Film Live Action. In all, I watched and reviewed a total of twenty-eight films based on acting, lighting, music, cinematography, costume/makeup/set design, writing, and visual effects. Over the course of nine months, I have watched, reviewed, and talked extensively about each film that I have reviewed. Though tedious at times, I thoroughly enjoyed completing my Undergraduate Thesis Project. I hope to continue critically looking at films, and possibly even incorporating film in my journalistic career.
ContributorsBecerra, Adriana Justina (Author) / Dodge, Nancie (Thesis director) / Russell, Dennis (Committee member) / School of Politics and Global Studies (Contributor) / Walter Cronkite School of Journalism and Mass Communication (Contributor) / Department of English (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
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Nitrous oxide (N2O) is a major contributor to the greenhouse effect and to stratospheric ozone depletion. In soils, nitrogen reduction is performed by biotic and abiotic processes, including microbial denitrification and chemical denitrification. Chemical denitrification, or chemodenitrification, is the abiotic step-wise reduction of nitrate (NO3-), nitrite (NO2-), or nitric oxide

Nitrous oxide (N2O) is a major contributor to the greenhouse effect and to stratospheric ozone depletion. In soils, nitrogen reduction is performed by biotic and abiotic processes, including microbial denitrification and chemical denitrification. Chemical denitrification, or chemodenitrification, is the abiotic step-wise reduction of nitrate (NO3-), nitrite (NO2-), or nitric oxide (NO) to N2O in anoxic environments, with high turnover rates particularly in acidic soils. Chemodenitrification was identified in various environments, but the mechanism is still not understood. In this study, the factors influencing abiotic reduction of NO2- to N2O in acidic tropical peat soil are examined. These factors include pH, organic matter content, and dissolved ferrous iron. Anoxic peat soil from sites located in the Peruvian Amazon was used for incubations. The results show that peat soil (pH ~4.5) appears to reduce NO2- more quickly in the presence of lower pH and higher Fe(II) concentrations. NO2- is completely reduced in excess Fe(II), and Fe(II) is completely oxidized in excess NO2-, providing evidence for the proposed mechanism of chemodenitrification. In addition, first order reaction rate constants kFe(II) and kNO2- were calculated using concentration measurements over 4 hours, to test for the hypothesized reaction rate relationships kFe(II): kFe(II) kFe(II)~NO2- > kFe(II)>NO2- and kNO2-: kFe(II)NO2-. The NO2- k values followed the anticipated pattern, although the Fe(II) k value data was inconclusive. Organic material may also play a role in NO2- reduction through chemodenitrification, and future experimentation will test this possibility. How and to what extent the pH and the concentrations of organic matter and Fe(II) affect the kinetic rate of chemodenitrification will lend insight into the N2O production potential of natural tropical peatlands.
ContributorsTylor, Kaitlyn Marie (Author) / Cadillo-Quiroz, Hinsby (Thesis director) / Day, Thomas (Committee member) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
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Sigmund Freud's psychoanalytic theory proposes that the personality has three components, the id, superego, and ego. The id is concerned with pleasure and gain, the reason it is often identified as a human's animalistic side. Additionally, the id does not consider social rules as closely and is the uncensored portion

Sigmund Freud's psychoanalytic theory proposes that the personality has three components, the id, superego, and ego. The id is concerned with pleasure and gain, the reason it is often identified as a human's animalistic side. Additionally, the id does not consider social rules as closely and is the uncensored portion of the personality. The superego is the id's opposite; the superego considers social expectations and pressures immensely, is more self-critical and moralizing. The ego mediates the id and superego, and is understood as the realistic expression of personality which considers both the "animal" and human. A Fractured Whole: A Collection of Short Stories, explores Freud's construction of human personality in both form and content. Within the collection are three sections, each with a different pair of characters. Within each section, the same scene is written in the three "modes" of the id, superego, and ego, as three separate stories. The fifteen stories comprising this collection address the substance of daily life: sexuality, body image, competition, among other topics, to consider how a single person can balance the desires for personal pleasure and to satisfy social expectations. Writing the same scene in three "modes" allows for the observation of how the characters attitudes and actions alter under the influence of different parts of their personalities.
ContributorsOtte, Aneka (Author) / Sturges, Robert (Thesis director) / Bryant, Jason (Committee member) / School of Historical, Philosophical and Religious Studies (Contributor) / Department of English (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
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The act of writing music criticism comes with numerous difficulties inherently involved in describing the ineffable qualities of audio in the medium of the written word. My music criticism podcast, Here and Now with Steve Jozef, offers a method of reviewing albums that sidesteps these problems by interweaving the criticism

The act of writing music criticism comes with numerous difficulties inherently involved in describing the ineffable qualities of audio in the medium of the written word. My music criticism podcast, Here and Now with Steve Jozef, offers a method of reviewing albums that sidesteps these problems by interweaving the criticism with clips of the songs discussed. This format holds the critic accountable to root their opinion in tangible components in the music, and makes clear the direct line between the qualities of the music at hand and the reviewer's verdict on that music. I wrote, recorded, edited, and distributed 13 episodes of the podcast over the course of six months; I've selected four of those episodes to represent my work for the purposes of the thesis. Their scripts, as well as links to the full episodes, are included with this paper. In addition, I thoroughly researched modern academic thought on the nature, purpose, and future of popular music criticism. This research helped me refine a conception of my ideal theoretical audience for the podcast, forced me to confront and assess my music evaluation criteria through various lenses, and develop the goal of creating a pattern of empathetic listening amongst my listeners. Over the course of developing the project, I ran into several obstacles in using copyrighted material on the show without permission from the copyright holders. Thus the podcast also became a case study in evaluating modern copyright law and its application, and demonstrating what needs to change about both for music criticism to sustain in this form.
ContributorsJozef, Steven James (Author) / Wells, Christopher (Thesis director) / Duerden, Sarah (Committee member) / Tinapple, David (Committee member) / Department of English (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
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Triops (Branchiopoda: Notostraca) and Streptocephalus (Branchiopoda: Anostraca) are two crustaceans which cohabitate in ephemeral freshwater pools. They both lay desiccation resistant eggs that disperse passively to new hydrologically isolated environments. The extent of genetic distance among regions and populations is of perennial interest in animals that live in such isolated

Triops (Branchiopoda: Notostraca) and Streptocephalus (Branchiopoda: Anostraca) are two crustaceans which cohabitate in ephemeral freshwater pools. They both lay desiccation resistant eggs that disperse passively to new hydrologically isolated environments. The extent of genetic distance among regions and populations is of perennial interest in animals that live in such isolated habitats. Populations in six natural ephemeral pool habitats located in two different regions of the Sonoran Desert and a transition area between the Sonoran and Chihuahuan Deserts were sampled. Sequences from Genbank were used for reference points in the determination of species as well as to further identify regional genetic distance within species. This study estimated the amount of within and between genetic distance of individuals from each region and population through the use of a neutral marker, cytochrome oxidase I (COI). We concluded that, although the method of passive dispersal may differ between the two genera, the differences do not results in different patterns of genetic distances between regions and populations. Furthermore, we only found the putative species, Triops longicaudatus "short", with enough distinct speciation. Although Triops longicaudatus "long" and Triops newberryi may be in the early stages of speciation, this study does not find enough support to conclude that they have separated.
ContributorsMurphy Jr., Patrick Joseph (Author) / Rutowski, Ronald (Thesis director) / Cartwright, Reed (Committee member) / Lessios, Nikos (Committee member) / School of Life Sciences (Contributor) / School of Human Evolution and Social Change (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
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Dogs' health and wellbeing is of great importance to their owners. The most common nutritional problem for pet dogs is obesity, with 22-40% of pet dogs being classified as overweight or obese. With many adverse health effects associated with obesity, this is a major concern for owners and veterinarians. The

Dogs' health and wellbeing is of great importance to their owners. The most common nutritional problem for pet dogs is obesity, with 22-40% of pet dogs being classified as overweight or obese. With many adverse health effects associated with obesity, this is a major concern for owners and veterinarians. The degree to which dogs enjoy consuming certain foods can have substantial implications for their body weight, so it is important to understand which aspects of foods make them appealing to dogs. This study aimed to determine whether nutritional aspects of commercial dog foods predict dogs' preferences for those foods. It was found that consumption preference is positively correlated with protein content (p < .001), therefore implying that the protein content of commercial dry dog foods may predict dogs' consumption preferences. Consumption preferences were not predicted by other available measures of food content or caloric value. Dogs' preference for foods high in protein content may be due to the satiating effect of protein. Since foods high in protein both reduce the amount of energy consumed and are found to be palatable to dogs, high-protein dog foods may offer a way for dog food manufacturers, veterinarians, and pet owners to combat obesity in pet dogs.
ContributorsPrevost, Emily Danielle (Author) / Wynne, Clive (Thesis director) / Hall, Nathaniel (Committee member) / School of Life Sciences (Contributor) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
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Learning how to manage time efficiently is something that many people struggle with, college students in particular. The purpose of this study was to examine if personalization via self-experimentation of strategies to improve time management skills is a useful strategy for achieving this goal. This study used a multiple baseline

Learning how to manage time efficiently is something that many people struggle with, college students in particular. The purpose of this study was to examine if personalization via self-experimentation of strategies to improve time management skills is a useful strategy for achieving this goal. This study used a multiple baseline approach with three phases: phase one, the baseline, phase two, which included individuals receiving examples of plausible strategies to improve time management skills, and phase three, which involved the self-experimentation component. Results of this study suggest no significant changes in time management based on self-reported completion of tasks but do indicate a trend towards improved time management skills overall based on the time management questionnaire taken at the beginning and end of the study. These results suggest that further exploration in the use of self-experimentation strategies for improving time management is likely warranted but that current strategies likely require additional research. Results from the interviews indicate that the self-experimentation strategy, as delivered via PACO does increase awareness and thinking about time management.
ContributorsCope, Breanna (Author) / Hekler, Eric (Thesis director) / Buman, Matthew (Committee member) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
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Transient Receptor Potential (TRP) ion channels are a diverse family of nonselective, polymodal sensors in uni- and multicellular eukaryotes that are implicated in an assortment of biological contexts and human disease. The cold-activated TRP Melastatin-8 (TRPM8) channel, also recognized as the human body's primary cold sensor, is among the few

Transient Receptor Potential (TRP) ion channels are a diverse family of nonselective, polymodal sensors in uni- and multicellular eukaryotes that are implicated in an assortment of biological contexts and human disease. The cold-activated TRP Melastatin-8 (TRPM8) channel, also recognized as the human body's primary cold sensor, is among the few TRP channels responsible for thermosensing. Despite sustained interest in the channel, the mechanisms underlying TRPM8 activation, modulation, and gating have proved challenging to study and remain poorly understood. In this thesis, I offer data collected on various expression, extraction, and purification conditions tested in E. Coli expression systems with the aim to optimize the generation of a structurally stable and functional human TRPM8 pore domain (S5 and S6) construct for application in structural biology studies. These studies, including the biophysical technique nuclear magnetic spectroscopy (NMR), among others, will be essential for elucidating the role of the TRPM8 pore domain in in regulating ligand binding, channel gating, ion selectively, and thermal sensitivity. Moreover, in the second half of this thesis, I discuss the ligation-independent megaprimer PCR of whole-plasmids (MEGAWHOP PCR) cloning technique, and how it was used to generate chimeras between TRPM8 and its nearest analog TRPM2. I review steps taken to optimize the efficiency of MEGAWHOP PCR and the implications and unique applications of this novel methodology for advancing recombinant DNA technology. I lastly present preliminary electrophysiological data on the chimeras, employed to isolate and study the functional contributions of each individual transmembrane helix (S1-S6) to TRPM8 menthol activation. These studies show the utility of the TRPM8\u2014TRPM2 chimeras for dissecting function of TRP channels. The average current traces analyzed thus far indicate that the S2 and S3 helices appear to play an important role in TRPM8 menthol modulation because the TRPM8[M2S2] and TRPM8[M2S3] chimeras significantly reduce channel conductance in the presence of menthol. The TRPM8[M2S4] chimera, oppositely, increases channel conductance, implying that the S4 helix in native TRPM8 may suppress menthol modulation. Overall, these findings show that there is promise in the techniques chosen to identify specific regions of TRPM8 crucial to menthol activation, though the methods chosen to study the TRPM8 pore independent from the whole channel may need to be reevaluated. Further experiments will be necessary to refine TRPM8 pore solubilization and purification before structural studies can proceed, and the electrophysiology traces observed for the chimeras will need to be further verified and evaluated for consistency and physiological significance.
ContributorsWaris, Maryam Siddika (Author) / Van Horn, Wade (Thesis director) / Redding, Kevin (Committee member) / School of Molecular Sciences (Contributor) / Department of English (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05