Matching Items (13)
Description
This thesis responds to the question, "Can Science Make Sense of Life?" through a structural lens of the Human Germline Genetic Editing debate. I explore who is absent from the table, and how the ways of thinking that dominate marginalize and exclude alternative frameworks and considerations. This analysis is centered around an examination of several perspectives from the disability community and an in-depth study of how the Orthodox Jewish community contends with genetic disease. These perspectives illuminate several lessons that prove to bring insight not merely to questions of permissibility on genetic editing, but also offer reflections on the larger relationship between science, technology, and society. I then return to the mainstream genetic editing debate to show how the culture it is born out of and the structures it has ingrained prevent lessons such as these from impacting the conversation. In light of such structures that continuously reproduce the assertion that it is science, not humanity, that is able to make sense of life, my final argument is that though science tends to gatekeep questions of emerging technologies by centering conversations on highly advanced and methodological considerations, public individuals need not feel as if they are irrelevant or unessential. Though science may offer one solution, it is the individuals and communities, not results from a lab, that are equipped to determine if it is the best solution.
ContributorsAsher, Michaela Elyse (Author) / Hurlbut, Ben (Thesis director) / Tirosh-Samuelson, Hava (Committee member) / School of Human Evolution & Social Change (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
Description
The ASU COVID-19 testing lab process was developed to operate as the primary testing site for all ASU staff, students, and specified external individuals. Tests are collected at various collection sites, including a walk-in site at the SDFC and various drive-up sites on campus; analysis is conducted on ASU campus and results are distributed virtually to all patients via the Health Services patient portal. The following is a literature review on past implementations of various process improvement techniques and how they can be applied to the ABCTL testing process to achieve laboratory goals. (abstract)
ContributorsKrell, Abby Elizabeth (Co-author) / Bruner, Ashley (Co-author) / Ramesh, Frankincense (Co-author) / Lewis, Gabriel (Co-author) / Barwey, Ishna (Co-author) / Myers, Jack (Co-author) / Hymer, William (Co-author) / Reagan, Sage (Co-author) / Compton, Carolyn (Thesis director) / McCarville, Daniel R. (Committee member) / Industrial, Systems & Operations Engineering Prgm (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
Description
This dissertation addresses the tendency among some disability scholars to overlook the importance of congenital deformity and disability in the pre-modern West. It argues that congenital deformity and disability deviated so greatly from able-bodied norms that they have played a pivotal role in the history of Western Civilization. In particular, it explores the evolution of two seemingly separate, but ultimately related, ideas from classical antiquity through the First World War: (1) the idea that there was some type of significance, whether supernatural or natural, to the existence of congenital deformity and (2) the idea that the existence of disabled people has resulted in a disability problem for western societies because many disabilities can hinder labor productivity to such an extent that large numbers of the disabled cannot survive without taking precious resources from their more productive, able-bodied counterparts. It also looks at how certain categories of disabled people, including, monsters, hunchbacks, cripples, the blind, the deaf and dumb, and dwarfs, which signified aesthetic and functional deviations from able-bodied norms, often reinforced able-bodied prejudices against the disabled.
ContributorsParry, Matthew (Author) / Fuchs, Rachel (Thesis advisor) / Tirosh-Samuelson, Hava (Committee member) / Wright, Johnson K. (Committee member) / Arizona State University (Publisher)
Created2013
Description
Coccidioidomycosis, also known as Valley Fever, is a disease caused by the dimorphic soil-dwelling fungus, Coccidioides sp. Coccidioidomycosis is difficult to diagnose because symptoms are similar to community-acquired pneumonia. Current diagnostic tests rely on antibody responses, but immune responses can be delayed and aberrant, resulting in false negative diagnoses. Unlike serology, detection of coccidioidal proteins or other fungal components in blood could distinguish valley fever from other pulmonary infections and provide a definitive diagnosis. Using mass spectrometry (LC-MS/MS) we examined the plasma peptidome from patients with serologically confirmed coccidioidomycosis. Mass spectra were searched using the protein database from the Coccidioides species, generated and annotated by the Broad Institute. 15 of 20 patients with serologically confirmed coccidioidomycosis demonstrated the presence of a peptide in plasma, "PGLDSKSLACTFSQV" (PGLD). The peptide is derived from an open reading frame from a "conserved hypothetical protein" annotated with 2 exons, and to date, found only in the C. posadasii strain Silviera RMSCC 3488 genomic sequence. In this thesis work, cDNA sequence analysis from polyadenylated RNA confirms the peptide sequence and genomic location of the peptide, but does not indicate that the intron in the gene prediction of C. posadasii strain Silviera RMSCC 3488 is present. A monoclonal antibody generated against the peptide bound to a 16kDa protein in T27K coccidioidal lysate. Detecting components of the fungus plasma could be a useful diagnostic tool, especially when serology does not provide a definitive diagnosis.
ContributorsDuffy, Stacy Leigh (Author) / Lake, Douglas (Thesis advisor) / Magee, Dewey Mitch (Committee member) / Antwi, Kwasi (Committee member) / Arizona State University (Publisher)
Created2013
Description
This dissertation analyzes the way in which leaders of certain Taiwanese Buddhist organizations associated with a strand of Buddhist modernism called "humanistic Buddhism" use discourse and rhetoric to make environmentalism meaningful to their members. It begins with an assessment of the field of religion and ecology, situating it in the context of secular environmental ethics. It identifies rhetoric and discourse as important but under acknowledged elements in literature on environmental ethics, both religious and secular, and relates this lack of attention to rhetoric to the presence of a problematic gap between environmental ethics theory and environmentalist practice. This dissertation develops a methodology of rhetorical analysis that seeks to assess how rhetoric contributes to alleviating this gap in religious environmentalism. In particular, this dissertation analyzes the development of environmentalism as a major element of humanistic Buddhist groups in Taiwan and seeks to show that a rhetorical analysis helps demonstrate how these organizations have sought to make environmentalism a meaningful subject of contemporary Buddhist religiosity. This dissertation will present an extended analysis of the concept of "spiritual environmentalism," a term developed and promoted by the late Ven. Shengyan (1930-2009), founder of the Taiwanese Buddhist organization Dharma Drum Mountain. Furthermore, this dissertation suggests that the rhetorical methodology proposed herein offers offers a direction for scholars to more effectively engage with religion and ecology in ways that address both descriptive/analytic approaches and constructive engagements with various forms of religious environmentalism.
ContributorsClippard, Seth (Author) / Chen, Huaiyu (Thesis advisor) / Tirosh-Samuelson, Hava (Committee member) / Bokenkamp, Stephen (Committee member) / Tillman, Hoyt (Committee member) / Minteer, Ben (Committee member) / Arizona State University (Publisher)
Created2012
Description
The following text is a re-evaluation of Robert Moore's persecuting society thesis in light of recent criticism. The Persecuting Society asserts that the fundamental condition of Jewish persecution in the 13th century was law and order. In other words, persecution had become an institutionalized phenomenon through which medieval Christians--particularly, the English and French monarchies--segregated, both geographically and ideologically, Jews in England and France. The character of such persecution was primarily economic, but based in religious roots. The paper thus also discusses the role of the Church in establishing and justifying social and economic controls against Jews within the English and French persecutional state apparatuses. The text affirms Moore's persecuting society thesis on two accounts: First, that the English and French crowns developed institutions which marginalized and persecuted Jews; secondly, that functionaries of the Church, particularly ecclesiastic functionaries and later popes of the 13th century, did so as well.
ContributorsAngulo, Zach Daniel (Author) / Tirosh-Samuelson, Hava (Thesis director) / Bruhn, Karen (Committee member) / Barrett, The Honors College (Contributor) / School of Historical, Philosophical and Religious Studies (Contributor)
Created2014-05
Description
Transhumanist concepts and themes increasingly occupy a prominent place in contemporary visions of the future, particularly with regard to technology. A growing number of scholars, including some self-described transhumanists, see transhumanism as functioning like a religion for secular people, in that it fulfills many of the same desires and impulses without reference to any supernatural forces. For this reason there is a growing discussion of transhumanism in comparison with major religious traditions, but one which has heretofore been underappreciated is Protestant pietism. Pietism grew out of a need among Protestants after the Reformation to realize a better Christian community and better prepare individual believers for the afterlife. It had a significant influence over the European Enlightenment, of which transhumanists claim to be the successors. In its understanding of human improvement, human nature, and ultimate human destiny in death and the end-point of history, pietism has multiple interesting points of comparison with transhumanism. Both ideologies begin by improving individual human beings as the primary means to the end of eliminating suffering, especially death and disease, and building the ideal human community. Transhumanism accomplishes its goals for humanity through the use of advanced technologies which enable human beings to transcend their natural limitations. Pietism focuses, as its name suggests, on moral and spiritual improvement according to practical guidelines that lead a Christian believer to take an active role in his or her own sanctification. This essay concludes that pietism reveals certain key limitations in transhumanism as a comprehensive life philosophy, especially in its ability to organize society according to its system of values.
ContributorsDepew, Mason James (Author) / Tirosh-Samuelson, Hava (Thesis director) / Bennett, Gaymon (Committee member) / School of Historical, Philosophical and Religious Studies (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
Description
The Norman invasion and conquest of England in 1066, led by Duke William "the Conqueror," is well-known in British history; less well-known is the fact that the conquest caused a group of Norman Jews to immigrate to England. These immigrants were the first significant population of Jews to ever reside in England, and by about 1100, distinct communities of Jews had established themselves in several cities throughout the country. However, Jewish life in England came to an abrupt end less than two-hundred and thirty years after its beginning when King Edward I expelled the entire Jewish population from England in 1290. The edict of expulsion was approved by the English parliament on June 18, 1290, and there are no surviving records of what happened in that meeting or why Edward decided to banish the Jews. Accordingly, there are a host of questions that need answering if one is to propose a explanation. For example, what could compel Edward I, who struggled financially and was deeply in debt for the duration of his reign, to expel the people who had been the crown's greatest asset for two centuries? Why did the king break the charter which specifically placed the Jews under the monarchy's protection? Why was the aristocracy so intent on getting rid of the Jews who, on several occasions, kept the baronies financially afloat through generous loans? My goal in writing this thesis is threefold: first, to provide a concise but clear account of this extraordinarily specific section of history; second, to present the information in such a way that those who read it might be convinced that the Expulsion was, in fact, primarily motivated by financial factors; and third, to identify several structural and institutional factors which were critical to the Jews' experiences in medieval England.
ContributorsMiller, Drew Beaupre (Author) / Tirosh-Samuelson, Hava (Thesis director) / Barth, Jonathan (Committee member) / School of Politics and Global Studies (Contributor) / School of Social Transformation (Contributor) / School of Historical, Philosophical and Religious Studies (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
Description
For as long as humans have been working, they have been looking for ways to get that work done better, faster, and more efficient. Over the course of human history, mankind has created innumerable spectacular inventions, all with the goal of making the economy and daily life more efficient. Today, innovations and technological advancements are happening at a pace like never seen before, and technology like automation and artificial intelligence are poised to once again fundamentally alter the way people live and work in society. Whether society is prepared or not, robots are coming to replace human labor, and they are coming fast. In many areas artificial intelligence has disrupted entire industries of the economy. As people continue to make advancements in artificial intelligence, more industries will be disturbed, more jobs will be lost, and entirely new industries and professions will be created in their wake. The future of the economy and society will be determined by how humans adapt to the rapid innovations that are taking place every single day. In this paper I will examine the extent to which automation will take the place of human labor in the future, project the potential effect of automation to future unemployment, and what individuals and society will need to do to adapt to keep pace with rapidly advancing technology. I will also look at the history of automation in the economy. For centuries humans have been advancing technology to make their everyday work more productive and efficient, and for centuries this has forced humans to adapt to the modern technology through things like training and education. The thesis will additionally examine the ways in which the U.S. education system will have to adapt to meet the demands of the advancing economy, and how job retraining programs must be modernized to prepare workers for the changing economy.
ContributorsCunningham, Reed P. (Author) / DeSerpa, Allan (Thesis director) / Haglin, Brett (Committee member) / School of International Letters and Cultures (Contributor) / Department of Finance (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
This Project Report documents the accomplishments of an extraordinary group of students, faculty, and staff at the Arizona state University, who participated in a year-long, multidisciplinary, first-of-its-kind academic endeavor entitled “The Making of a COVID Lab.” The lab that is the focus of this project is the ASU Biodesign Clinical Testing Laboratory, known simply as the ABCTL.
ContributorsCompton, Carolyn C. (Project director) / Christianson, Serena L. (Project director) / Floyd, Christopher (Project director) / Schneller, Eugene S (Research team head) / Rigoni, Adam (Research team head) / Stanford, Michael (Research team head) / Cheong, Pauline (Research team head) / McCarville, Daniel R. (Research team head) / Dudley, Sean (Research team head) / Blum, Nita (Research team head) / Magee, Mitch (Research team head) / Agee, Claire (Research team member) / Cosgrove, Samuel (Research team member) / English, Corinne (Research team member) / Mattson, Kyle (Research team member) / Qian, Michael (Research team member) / Espinoza, Hale Anna (Research team member) / Filipek, Marina (Research team member) / Jenkins, Landon James (Research team member) / Ross, Nathaniel (Research team member) / Salvatierra, Madeline (Research team member) / Serrano, Osvin (Research team member) / Wakefield, Alex (Research team member) / Calo, Van Dexter (Research team member) / Nofi, Matthew (Research team member) / Raymond, Courtney (Research team member) / Barwey, Ishna (Research team member) / Bruner, Ashley (Research team member) / Hymer, William (Research team member) / Krell, Abby Elizabeth (Research team member) / Lewis, Gabriel (Research team member) / Myers, Jack (Research team member) / Ramesh, Frankincense (Research team member) / Reagan, Sage (Research team member) / Kandan, Mani (Research team member) / Knox, Garrett (Research team member) / Leung, Michael (Research team member) / Schmit, Jacob (Research team member) / Woo, Sabrina (Research team member) / Anderson, Laura (Research team member) / Breshears, Scott (Research team member) / Majhail, Kajol (Research team member) / Ruan, Ellen (Research team member) / Smetanick, Jennifer (Research team member) / Bardfeld, Sierra (Research team member) / Cura, Joriel (Research team member) / Dholaria, Nikhil (Research team member) / Foote, Hannah (Research team member) / Liu, Tara (Research team member) / Raymond, Julia (Research team member) / Varghese, Mahima (Research team member)
Created2021