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Description
As the student union on Arizona State University’s main Tempe campus, the MU should be a model of building sustainability. After a fire engulfed the MU’s second floor in 2007, the building underwent major renovations and achieved LEED v2.0: Commercial Interiors (LEED CI) Gold certification. Since then, more up-to-date building certification programs have been established, including the Green Globes (GG) green building rating system and a more recent version of LEED that suits the MU’s situation—Existing Buildings: Operations and Maintenance (LEED EB:OM). This paper performs a cost-benefit analysis of these rating systems, specifically looking at 1) national recognition, 2) ease of use, 3) amount of resources needed to invest, 4) length of time of the certification process, 5) certification fees and costs, 6) pre-requisites and system structure of point allotment, and 7) flexibility of the systems. A review of the previous LEED CI certification of the MU addresses 1) solar panel installation and renewable energy achievements, 2) improvement of indoor air quality, 3) application of sustainable construction practices, 4) missed opportunities since renovations were not performed on the entire building, 5) water efficiency scoring, and 6) lack of significant Energy & Atmosphere improvements. A proposal for the university to consider LEED EB:OM certification for the Memorial Union will be presented, analyzing the points already secured by campus-wide programs and policies, credits that are possible with minimal funding, and elaborating on opportunities already planned for completion, including 1) the Power Parasol project, 2) “Zero Waste by 2015” and “Carbon Neutrality” programs and goals, and 3) plans for alternative transportation methods through the Tempe Campus Access Management Plan. In conclusion, my recommendation to pursue LEED EB:OM and achieve Silver level will be presented. With the majority of LEED points already secured and several on the horizon, certifying the MU under LEED EB:OM will set an example and increase the amount of existing buildings on campus to pursue LEED certification. University-wide policies on green cleaning, sustainable purchasing, alternative energy sources, carbon neutrality, and LEED for Multiple Buildings all contribute to simplifying the LEED certification process for ASU buildings campus-wide.
ContributorsHeppner, Mary Catherine (Author) / Brown, Nicholas (Thesis director) / Martin, Thomas (Committee member) / Bogart, Brooke (Committee member) / Barrett, The Honors College (Contributor) / School of Letters and Sciences (Contributor) / T. Denny Sanford School of Social and Family Dynamics (Contributor)
Created2013-05
Description
The Community Action Research Experiences program integrates the research and teaching mission of Arizona State University by providing services to the community by fostering professional and leadership development of students. It is hoped that the results of the collaborations with CARE will serve to further an organization's goals and effectiveness. VALLEYLIFE (VL) is a non-profit organization striving to help people with disabilities. VL develops Action Programs for each of its clients, whom they call members, to improve their independent or social skills. Examples of programs that members may work on include tasks such as computer training, visual arts, or writing. VALLEYLIFE lacked the data to evaluate if the developed and implemented Action Programs are properly carried out by the staff in ways that are beneficial to members. Given the problem, this research project sought to conduct a process evaluation of the staff regarding their implementation of the Action Programs. This involved observations of employee-member interactions in performing the Action Programs and an interview of staff measuring their preparedness and confidence in performing the program and their feelings of the programs and how things are run. This research provided the following implications to VALLEYLIFE. VL might consider performing periodic observations and reviews of the program implementation to monitor quality. VL may consider involving staff in program development and revision to create programs that better serve members. VL may consider generating ideas for how they may cooperate when a peer is struggling to keep up with events that happen through the day in the interest of better serving the members. Overall, employees are doing well as they are efficient in carrying out the written programs during program time. They are comfortable with what they are doing, use time effectively, and do their best to help the members. There is always room for improvement however and by considering some of the implications mentioned, VALLEYLIFE and their employees may be able to take action that may hold potential for further improvements in effectiveness.
ContributorsAbalos, Cherylene Sales (Author) / Bradley, Robert (Thesis director) / Dumka, Larry (Committee member) / Goldblatt, Lois (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor) / T. Denny Sanford School of Social and Family Dynamics (Contributor)
Created2013-05
Description
Children's speech and language development is measured by performance on standardized articulation tests. Test items on these assessments, however, vary in length and complexity. Word complexity was compared across five articulation tests: the Assessment of Phonological Patterns-Revised (APP-R), the Bankson-Bernthal Test of Phonology (BBTOP), the Clinical Assessment of Articulation and Phonology (CAAP), the Goldman-Fristoe Test of Articulation (GFTA), and the Assessment of Children's Articulation and Phonology (ACAP). Four groups of word complexity were used, using the dimensions of monosyllabic vs. multisyllabic words, and words with consonant clusters vs. words without consonant clusters. The measure of phonological mean length of utterance (Ingram, 2001), was used to assess overall word complexity. It was found that the tests varied in number of test items and word complexity, with the BBTOP and the CAAP showing the most similarity to word complexity in spontaneous speech of young children. On the other hand, the APP-R used the most complex words and showed the least similarity. Additionally, case studies were analyzed for three of the tests to examine the effect of word complexity on consonant correctness, usedin the measures of Percentage of Correct Consonants (PCC) and the Proportion of Whole Word Proximity (PWP). Word complexity was found to affect consonant correctness, therefore affecting test performance.
ContributorsSullivan, Katherine Elizabeth (Author) / Ingram, David (Thesis director) / Bacon, Cathy (Committee member) / Brown, Jean (Committee member) / Barrett, The Honors College (Contributor) / Department of Speech and Hearing Science (Contributor) / T. Denny Sanford School of Social and Family Dynamics (Contributor)
Created2013-05
Description
Utilizing a compilation of existing literature, theory and current praxis, a clear case for instituting a needle exchange in Maricopa County is visible.. Research on HIV rates are consulted to establish a foundation for understanding the value of needle exchange programs nationally and in Maricopa County. Case studies on existing needle exchange efficacy are also used to support the proposal and outline the success of needle exchanges in reducing rates of infection.
ContributorsGuntermann, Christel Young Shin (Author) / Jacobs, Bertram (Thesis director) / Jackson, Danielle (Committee member) / Taylor, Emily (Committee member) / Barrett, The Honors College (Contributor) / T. Denny Sanford School of Social and Family Dynamics (Contributor) / School of Community Resources and Development (Contributor)
Created2013-05
Description
Our goal was to design a method to express soluble folded major histocompatibility complex (MHC) proteins using human cell line HeLa lysate with the novel 1-Step Human In Vitro Protein Expression by Thermo Scientific in the presence of β2 microglobulin (β2m) and antigenic peptide.
We confirmed that the soluble protein MHC-A2.1 could be successfully attached to the Luminex magnetic beads and detected using the primary antibody anti-GST and the detection antibody goat mAb mouse PE. The average net MFI of the attached pA2.1-bead complex was 8182. Biotinylated A2.1 MHC complexes pre-folded with β2m and FLU M1 peptide (A2.1 monomers) were also successfully attached to Luminex magnetic beads and detected with BB7.2. The average net MFI of the detected A2.1 monmer-bead complexes was 318. The protein MHC complexes were multimerized on magnetic beads to create MHC tetramers and detected with BB7.2, PE labeled monoclonal antibody, via median fluorescent intensity with the Luminex platform. Varying protein, β2 microglobulin (β2m), and peptide concentrations were tested in a number of MHC-A2.1 protein refolding trials. Different antigenic peptides and attachment methods were also tested. However, none of the MHC-A2.1 protein folding and capture trials were successful. Although MHC-A2.1 complexes and recombinant MHC molecules could be attached to Luminex magnetic beads and be detected by Luminex arrays, soluble protein A2.1 could not be successfully expressed, refolded, captured onto Luminex beads, and detected. All refolding trials resulted in a net MFI of <25. The failed refolding and capture trials of A2.1 lead to the conclusion that human cell line HeLa lysate cannot be used to properly fold MHC molecules. However, efforts to refold the complexes onto Luminex magnetic beads are ongoing. We are also using the baculovirus expression system to refold soluble A2.1 lysate onto peptide-bead complexes.
We confirmed that the soluble protein MHC-A2.1 could be successfully attached to the Luminex magnetic beads and detected using the primary antibody anti-GST and the detection antibody goat mAb mouse PE. The average net MFI of the attached pA2.1-bead complex was 8182. Biotinylated A2.1 MHC complexes pre-folded with β2m and FLU M1 peptide (A2.1 monomers) were also successfully attached to Luminex magnetic beads and detected with BB7.2. The average net MFI of the detected A2.1 monmer-bead complexes was 318. The protein MHC complexes were multimerized on magnetic beads to create MHC tetramers and detected with BB7.2, PE labeled monoclonal antibody, via median fluorescent intensity with the Luminex platform. Varying protein, β2 microglobulin (β2m), and peptide concentrations were tested in a number of MHC-A2.1 protein refolding trials. Different antigenic peptides and attachment methods were also tested. However, none of the MHC-A2.1 protein folding and capture trials were successful. Although MHC-A2.1 complexes and recombinant MHC molecules could be attached to Luminex magnetic beads and be detected by Luminex arrays, soluble protein A2.1 could not be successfully expressed, refolded, captured onto Luminex beads, and detected. All refolding trials resulted in a net MFI of <25. The failed refolding and capture trials of A2.1 lead to the conclusion that human cell line HeLa lysate cannot be used to properly fold MHC molecules. However, efforts to refold the complexes onto Luminex magnetic beads are ongoing. We are also using the baculovirus expression system to refold soluble A2.1 lysate onto peptide-bead complexes.
ContributorsChang, Peter S (Author) / Anderson, Karen (Thesis director) / Chang, Yung (Committee member) / Sundaresan, Krishna (Committee member) / Barrett, The Honors College (Contributor) / T. Denny Sanford School of Social and Family Dynamics (Contributor) / Department of Chemistry and Biochemistry (Contributor)
Created2013-05
Description
Identifying disease biomarkers may aid in the early detection of breast cancer and improve patient outcomes. Recent evidence suggests that tumors are immunogenic and therefore patients may launch an autoantibody response to tumor associated antigens. Single-chain variable fragments of autoantibodies derived from regional lymph node B cells of breast cancer patients were used to discover these tumor associated biomarkers on protein microarrays. Six candidate biomarkers were discovered from 22 heavy chain-only variable region antibody fragments screened. Validation tests are necessary to confirm the tumorgenicity of these antigens. However, the use of single-chain variable autoantibody fragments presents a novel platform for diagnostics and cancer therapeutics.
ContributorsSharman, M. Camila (Author) / Magee, Dewey (Mitch) (Thesis director) / Wallstrom, Garrick (Committee member) / Petritis, Brianne (Committee member) / Barrett, The Honors College (Contributor) / College of Liberal Arts and Sciences (Contributor) / Virginia G. Piper Center for Personalized Diagnostics (Contributor) / Biodesign Institute (Contributor)
Created2012-12
Description
In September 1974, a guerrilla organization called the Montoneros captured Juan and Jorge Born, two Argentinean heirs to a massive food processing conglomerate, and held them for ransom. After months of negotiations between this radical political group and the brothers' family, the Montoneros received $61.5 million dollars for the brothers' re- lease. Other kidnappings followed, netting the revolutionaries close to $100 million dol- lars. Although their tactics initially brought them recognition, they also unleashed a vio- lent response. Through a military coup, General Jorge Videla assumed power and used counterinsurgency tactics against the radical left wing of the Peronist party members. The coming years of military repression put an end to the revolutionary efforts of the Mon- toneros and gave the military leaders a reputation of violators of human rights. Even the Argentine people called the repression the "Dirty War," and investigations estimate that 30,000 people, the Montoneros among them, disappeared.
ContributorsScarvie, Matthew (Author) / Stoner, Kathryn (Thesis director) / Hinojosa, Magda (Committee member) / Mitchell, Michael (Committee member) / Barrett, The Honors College (Contributor) / College of Liberal Arts and Sciences (Contributor)
Created2012-12
Description
While the use of super-cooled gasses as a tool for the study of macroscopic quantum effects has only become experimentally viable in recent years, theories involing such gasses have existed almost as long as quantum theory itself. Albert Einstein first proposed the concept of what is known today as a Bose-Einstein condensate; the driving principle behind his theory was a deliberate exploitation of the symmetric property of multiparticle bosonic wavefunctions. Specifically, since the Bose-Einstein statistics of bosons dic- tate that any arbitrary number of particles can occupy the same state, it is possible in an extremely low energy environment for particles on the order of Avagadro's number to all condense into the ground state. This state of matter is now called a Bose-Einstein condensate (hereafter referred to as a BEC). This state of matter is interesting because having such a large number of particles in the same state allows for the observation of macroscopic quantum effects.
ContributorsSpencer, Kwit (Author) / Schmidt, Kevin (Thesis director) / Treacy, Michael (Committee member) / Dawson, Colby (Committee member) / Barrett, The Honors College (Contributor) / College of Liberal Arts and Sciences (Contributor)
Created2012-12
Description
Organizations use news releases to promote coverage of its operations and enhance the image and issues pertinent to the organization. In most cases, the primary focus of press releases and news media coverage differs. This thesis analyzes the resonance between coverage by news organizations and the materials released by the organization. Analysis of coverage by the news media and the NBA illustrates the resonance and connections in coverage by all three organizations. It also shows how information regarding the NBA lockout released by the NBA and news outlets can be differentiated into unique issue arenas. These issue arenas can have influence on each other, while also allowing organizations to provide their own unique perspectives.
ContributorsEckert, Marshall (Author) / Gilpin, Dawn (Thesis director) / Matera, Fran (Committee member) / Barrett, The Honors College (Contributor) / College of Liberal Arts and Sciences (Contributor) / Walter Cronkite School of Journalism and Mass Communication (Contributor)
Created2012-12
Description
The use of medical scribes in emergency departments has been associated with faster patient discharge times, increased numbers of patients treated, and improved patient satisfaction ratings in previous research studies and has also been correlated with improved levels of physician satisfaction as well as a high degree of gratification from scribes. For this paper, I examined the nature of scribing, essentially analyzing the role of the scribe in modern healthcare, and the effects of the occupation on the medical field. Though a shortage of prior research regarding medical scribing persisted, the data I received here mirrored some of the results from earlier studies, specifically those which proclaimed that physicians admit to increased work efficiency when accompanied by scribes. Unlike prior studies, however, this thesis presents novel information regarding scribes‘ perspectives of the profession, including some of the complaints they possess, which are most notably long and irregular shifts, far commute distances, and low wages. Through my research, which relied heavily on interviews and surveys and less heavily on EMR-simulating examinations, scribes were discovered to have a greater average typing speed (64 wpm) than physicians (30 wpm) and performed better in three drills that simulated different manners of patient charting. It was the opinion of all physicians that scribes were beneficial—both to them as physicians and to patients. Though scribes represented varying opinions about their role, the majority (9/11) of those who were interviewed classified scribing as a somewhat stressful job but also stated that they were mostly satisfied with their position.
ContributorsAguirre, Abel (Author) / Robert, Jason (Thesis director) / Maienschein, Jane (Committee member) / Ellison, Karin (Committee member) / Barrett, The Honors College (Contributor) / College of Liberal Arts and Sciences (Contributor) / School of Life Sciences (Contributor)
Created2012-12