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Review of Autism Treatment Research

Description
As the prevalence and awareness of Autism Spectrum Disorder (ASD) increases, so does the variety of treatment options for primary symptoms (social interaction, communication, behavior) and secondary symptoms (anxiety, hyperactivity, GI problems, and insomnia). Various treatments, from Adderall to Citalopram to Flax Seed Oil promise relief for these symptoms. However,…

As the prevalence and awareness of Autism Spectrum Disorder (ASD) increases, so does the variety of treatment options for primary symptoms (social interaction, communication, behavior) and secondary symptoms (anxiety, hyperactivity, GI problems, and insomnia). Various treatments, from Adderall to Citalopram to Flax Seed Oil promise relief for these symptoms. However, very little research has actually been done on some of these treatments. Additionally, the research that has been done fails to compare these treatments against one another in terms of symptom relief. The Autism Treatment Effectiveness Survey, written by Dr. James Adams, director of the Autism/Asperger's Research Program at ASU, and graduate student/program coordinator Devon Coleman, aims to fill this gap. The survey numerically rates medications based on benefit and adverse effects, in addition to naming specific symptoms that are impacted by the treatments. However, the survey itself was retrospective in nature and requires further evidence to support its claims. Therefore, the purpose of this research paper is to evaluate evidence related to the results of the survey. After the performing an extensive literature review of over 70 different treatments, it appears that the findings of the Autism Treatment Effectiveness Survey are generally well supported. There were a few minor discrepancies regarding the primary benefitted symptom, but there was not enough of a conflict to discount the information from the survey. As research is still ongoing, conclusions cannot yet be drawn for Nutritional Supplements, although the current data looks promising.
ContributorsAnderson, Amy Lynn (Author) / Adams, James (Thesis director) / Coleman, Devon (Committee member) / School of Nutrition and Health Promotion (Contributor) / W.P. Carey School of Business (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
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Prenatal Supplementation Research

Description
When viewing vitamins and minerals, it is seen that they are essential for human life and vital for pregnancy. When paired with a healthy diet, prenatal supplements can allow for a healthy pregnancy and reduced maternal and infant health problems. Within this thesis, I was able to break down each…

When viewing vitamins and minerals, it is seen that they are essential for human life and vital for pregnancy. When paired with a healthy diet, prenatal supplements can allow for a healthy pregnancy and reduced maternal and infant health problems. Within this thesis, I was able to break down each vitamin and mineral necessary for a healthy pregnancy and birth. Further, I had the opportunity to dive into the addition of Omega-3 Fatty Acid during pregnancy to add more evidence to the study.
ContributorsSaad, Sophia Saad (Author) / Adams, James (Thesis director) / Haiwei, Gu (Committee member) / Coleman, Devon (Committee member) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2020-12
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Fault Trace Mapping Along the Creeping Section of the Central San Andreas Fault

Description
This study focuses on mapping faults along the Creeping Section of the San Andreas Fault (CSAF) in California between San Juan Bautista (121.54°W 36.85°N) and Parkfield (120.41°W 35.87°N). I synthesize high-quality base data, including and lidar topography from B4, EarthScope, and USGS 3DEP, recent maps of decadal-scale along-fault shear strain,…

This study focuses on mapping faults along the Creeping Section of the San Andreas Fault (CSAF) in California between San Juan Bautista (121.54°W 36.85°N) and Parkfield (120.41°W 35.87°N). I synthesize high-quality base data, including and lidar topography from B4, EarthScope, and USGS 3DEP, recent maps of decadal-scale along-fault shear strain, and aerial and satellite imagery. Using these data, I produced (covering 150 km at 1:10,000 scale) three geospatial map datasets with attributes: geomorphic indicators of faulting, surficial geology, and active fault traces.The CSAF's creeping movement, though likely not associated with large earthquakes, has the potential to cause damage to infrastructure. Accurate fault mapping facilitates fault displacement hazard assessment. This type of work is useful for California state regulations, particularly the Alquist-Priolo Act of 1972, providing insights for engineering site assessments and fault exclusion zones. I discern, categorize, and rank geomorphic indicators to support fault line placement. This approach contributes to the identification of surface expression of creeping faults where the surface has undergone alteration in response to displacement along the fault. I created a surficial geologic map spanning from San Juan Bautista to the southern extent of EarthScope lidar coverage (120.59°W 36.03°N). I categorized each fault as either a primary or secondary fault trace and further broke them into confidence levels based on interpretations of indicators along with structural geologic reasoning and topographic patterns. Accessible target areas containing initial low confidence mapping or interesting structures were visited in the field. Zones along the creeping section exhibit structures such as a pressure ridge found 25 km north of Parkfield, sigmoidal faults and sagponds observed near Paicines Ranch (121.29°W 36.68°N), en-echelon faults, horsetail splays and Riedel shear structures near Lewis Creek (120.87°W 36.29°N). Controls on the structural style along the CSAF are the results of geologic units through which the faults cut and fault zone width and trend.
ContributorsPowell, Joseph Hoss (Author) / Arrowsmith, Ramon (Thesis advisor) / Scott, Chelsea (Thesis advisor) / DeVecchio, Duane (Committee member) / DeLong, Stephen (Committee member) / Arizona State University (Publisher)
Created2023
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Spatio-Temporal Mapping of Plate Boundary Faults in California Using Geodetic Imaging

Description

The Pacific–North American plate boundary in California is composed of a 400-km-wide network of faults and zones of distributed deformation. Earthquakes, even large ones, can occur along individual or combinations of faults within the larger plate boundary system. While research often focuses on the primary and secondary faults, holistic study…

The Pacific–North American plate boundary in California is composed of a 400-km-wide network of faults and zones of distributed deformation. Earthquakes, even large ones, can occur along individual or combinations of faults within the larger plate boundary system. While research often focuses on the primary and secondary faults, holistic study of the plate boundary is required to answer several fundamental questions. How do plate boundary motions partition across California faults? How do faults within the plate boundary interact during earthquakes? What fraction of strain accumulation is relieved aseismically and does this provide limits on fault rupture propagation? Geodetic imaging, broadly defined as measurement of crustal deformation and topography of the Earth’s surface, enables assessment of topographic characteristics and the spatio-temporal behavior of the Earth’s crust.

We focus here on crustal deformation observed with continuous Global Positioning System (GPS) data and Interferometric Synthetic Aperture Radar (InSAR) from NASA’s airborne UAVSAR platform, and on high-resolution topography acquired from lidar and Structure from Motion (SfM) methods. Combined, these measurements are used to identify active structures, past ruptures, transient motions, and distribution of deformation. The observations inform estimates of the mechanical and geometric properties of faults. We discuss five areas in California as examples of different fault behavior, fault maturity and times within the earthquake cycle: the M6.0 2014 South Napa earthquake rupture, the San Jacinto fault, the creeping and locked Carrizo sections of the San Andreas fault, the Landers rupture in the Eastern California Shear Zone, and the convergence of the Eastern California Shear Zone and San Andreas fault in southern California. These examples indicate that distribution of crustal deformation can be measured using interferometric synthetic aperture radar (InSAR), Global Navigation Satellite System (GNSS), and high-resolution topography and can improve our understanding of tectonic deformation and rupture characteristics within the broad plate boundary zone.
ContributorsDonnellan, Andrea (Author) / Arrowsmith, Ramon (Author) / DeLong, Stephen (Author) / College of Liberal Arts and Sciences (Contributor)
Created2017-03-21