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The elaborate signals of animals are often costly to produce and maintain, thus communicating reliable information about the quality of an individual to potential mates or competitors. The properties of the sensory systems that receive signals can drive the evolution of these signals and shape their form and function. However,

The elaborate signals of animals are often costly to produce and maintain, thus communicating reliable information about the quality of an individual to potential mates or competitors. The properties of the sensory systems that receive signals can drive the evolution of these signals and shape their form and function. However, relatively little is known about the ecological and physiological constraints that may influence the development and maintenance of sensory systems. In the house finch (Carpodacus mexicanus) and many other bird species, carotenoid pigments are used to create colorful sexually selected displays, and their expression is limited by health and dietary access to carotenoids. Carotenoids also accumulate in the avian retina, protecting it from photodamage and tuning color vision. Analogous to plumage carotenoid accumulation, I hypothesized that avian vision is subject to environmental and physiological constraints imposed by the acquisition and allocation of carotenoids. To test this hypothesis, I carried out a series of field and captive studies of the house finch to assess natural variation in and correlates of retinal carotenoid accumulation and to experimentally investigate the effects of dietary carotenoid availability, immune activation, and light exposure on retinal carotenoid accumulation. Moreover, through dietary manipulations of retinal carotenoid accumulation, I tested the impacts of carotenoid accumulation on visually mediated foraging and mate choice behaviors. My results indicate that avian retinal carotenoid accumulation is variable and significantly influenced by dietary carotenoid availability and immune system activity. Behavioral studies suggest that retinal carotenoid accumulation influences visual foraging performance and mediates a trade-off between color discrimination and photoreceptor sensitivity under dim-light conditions. Retinal accumulation did not influence female choice for male carotenoid-based coloration, indicating that a direct link between retinal accumulation and sexual selection for coloration is unlikely. However, retinal carotenoid accumulation in males was positively correlated with their plumage coloration. Thus, carotenoid-mediated visual health and performance or may be part of the information encoded in sexually selected coloration.
ContributorsToomey, Matthew (Author) / McGraw, Kevin J. (Thesis advisor) / Deviche, Pierre (Committee member) / Smith, Brian (Committee member) / Rutowski, Ronald (Committee member) / Verrelli, Brian (Committee member) / Arizona State University (Publisher)
Created2011
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Diseases have been part of human life for generations and evolve within the population, sometimes dying out while other times becoming endemic or the cause of recurrent outbreaks. The long term influence of a disease stems from different dynamics within or between pathogen-host, that have been analyzed and studied by

Diseases have been part of human life for generations and evolve within the population, sometimes dying out while other times becoming endemic or the cause of recurrent outbreaks. The long term influence of a disease stems from different dynamics within or between pathogen-host, that have been analyzed and studied by many researchers using mathematical models. Co-infection with different pathogens is common, yet little is known about how infection with one pathogen affects the host's immunological response to another. Moreover, no work has been found in the literature that considers the variability of the host immune health or that examines a disease at the population level and its corresponding interconnectedness with the host immune system. Knowing that the spread of the disease in the population starts at the individual level, this thesis explores how variability in immune system response within an endemic environment affects an individual's vulnerability, and how prone it is to co-infections. Immunology-based models of Malaria and Tuberculosis (TB) are constructed by extending and modifying existing mathematical models in the literature. The two are then combined to give a single nine-variable model of co-infection with Malaria and TB. Because these models are difficult to gain any insight analytically due to the large number of parameters, a phenomenological model of co-infection is proposed with subsystems corresponding to the individual immunology-based model of a single infection. Within this phenomenological model, the variability of the host immune health is also incorporated through three different pathogen response curves using nonlinear bounded Michaelis-Menten functions that describe the level or state of immune system (healthy, moderate and severely compromised). The immunology-based models of Malaria and TB give numerical results that agree with the biological observations. The Malaria--TB co-infection model gives reasonable results and these suggest that the order in which the two diseases are introduced have an impact on the behavior of both. The subsystems of the phenomenological models that correspond to a single infection (either of Malaria or TB) mimic much of the observed behavior of the immunology-based counterpart and can demonstrate different behavior depending on the chosen pathogen response curve. In addition, varying some of the parameters and initial conditions in the phenomenological model yields a range of topologically different mathematical behaviors, which suggests that this behavior may be able to be observed in the immunology-based models as well. The phenomenological models clearly replicate the qualitative behavior of primary and secondary infection as well as co-infection. The mathematical solutions of the models correspond to the fundamental states described by immunologists: virgin state, immune state and tolerance state. The phenomenological model of co-infection also demonstrates a range of parameter values and initial conditions in which the introduction of a second disease causes both diseases to grow without bound even though those same parameters and initial conditions did not yield unbounded growth in the corresponding subsystems. This results applies to all three states of the host immune system. In terms of the immunology-based system, this would suggest the following: there may be parameter values and initial conditions in which a person can clear Malaria or TB (separately) from their system but in which the presence of both can result in the person dying of one of the diseases. Finally, this thesis studies links between epidemiology (population level) and immunology in an effort to assess the impact of pathogen's spread within the population on the immune response of individuals. Models of Malaria and TB are proposed that incorporate the immune system of the host into a mathematical model of an epidemic at the population level.
ContributorsSoho, Edmé L (Author) / Wirkus, Stephen (Thesis advisor) / Castillo-Chavez, Carlos (Thesis advisor) / Chowell-Puente, Gerardo (Committee member) / Arizona State University (Publisher)
Created2011
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Coverage of Black soccer players by Italian media outlets perpetuate narratives rooted in anti-Black racism. These narratives reflect the country’s changing attitude toward immigration. Historically a country from which citizens emigrated, it is now a recipient of immigrants from Africa. These changing demographics have also caused a shift in the

Coverage of Black soccer players by Italian media outlets perpetuate narratives rooted in anti-Black racism. These narratives reflect the country’s changing attitude toward immigration. Historically a country from which citizens emigrated, it is now a recipient of immigrants from Africa. These changing demographics have also caused a shift in the focus of racism in Italy, from discrimination against southern Italians to anti-Black racism. As the country has explored what defines a unified Italian identity, Afro-Italians have been excluded. This study evaluates how these perceptions of Afro-Italian soccer players manifest according to various racial frames, and the frequency with which they do so in three Italian sports dailies: La Gazzetta dello Sport, Corriere dello Sport – Stadio, and Tuttosport. In this context, Afro-Italian refers to an Italian citizen of African descent, and anti-Black racism denotes any form of discrimination, stereotyping, or racism that specifically impacts those of African descent. For this study, a representative sample was collected consisting of website coverage published by the three sports dailies: articles devoted to Mario Balotelli that appeared between 2007 and 2014, and articles devoted to Moise Kean between 2016 and 2019. Three coders recorded the content of the sample articles on a spreadsheet organized by the type of racial frame applied to Black athletes. The analysis reveals that the players were frequently portrayed as being incapable of self-determination and of having an innate, natural athletic capability, rather than one honed through practice. The coders noted that in addition to explicit racial framing, there were also instances of implicit and subtle ways these racial frames manifest. In future research, the coding procedure will need to be adapted to account for these more layered and nuanced manifestations of anti-Black racism.

Created2021-05
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When examining the average college campus, it becomes obvious that students feel rushed from one place to another as they try to participate in class, clubs, and extracurricular activities. One way that students can feel more comfortable and relaxed around campus is to introduce the aspect of gaming. Studies show

When examining the average college campus, it becomes obvious that students feel rushed from one place to another as they try to participate in class, clubs, and extracurricular activities. One way that students can feel more comfortable and relaxed around campus is to introduce the aspect of gaming. Studies show that “Moderate videogame play has been found to contribute to emotional stability” (Jones, 2014). This demonstrates that the stress of college can be mitigated by introducing the ability to interact with video games. This same concept has been applied in the workplace, where studies have shown that “Gaming principles such as challenges, competition, rewards and personalization keep employees engaged and learning” (Clark, 2020). This means that if we manage to gamify the college experience, students will be more engaged which will increase and stabilize the retention rate of colleges which utilize this type of experience. Gaming allows students to connect with their peers in a casual environment while also allowing them to find resources around campus and find new places to eat and relax. We plan to gamify the college experience by introducing augmented reality in the form of an app. Augmented reality is “. . . a technology that combines virtual information with the real world” (Chen, 2019). College students will be able to utilize the resources and amenities available to them on campus while completing quests that help them within the application. This demonstrates the ability for video games to engage students using artificial tasks but real actions and experiences which help them feel more connected to campus. Our Founders Lab team has developed and tested an AR application that can be used to connect students with their campus and the resources available to them.

ContributorsKlein, Jonathan (Co-author) / Rangarajan, Padmapriya (Co-author) / Li, Shimei (Co-author) / Byrne, Jared (Thesis director) / Pierce, John (Committee member) / School of International Letters and Cultures (Contributor) / Department of Management and Entrepreneurship (Contributor) / Sandra Day O'Connor College of Law (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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Before the COVID-19 pandemic, there was a great need for United States’ restaurants to “go green” due to consumers’ habits of frequently eating out. Unfortunately, COVID-19 has caused this initiative to lose traction. While the amount of customers ordering takeout has increased, there is less emphasis on sustainability.<br/>Plastic is known

Before the COVID-19 pandemic, there was a great need for United States’ restaurants to “go green” due to consumers’ habits of frequently eating out. Unfortunately, COVID-19 has caused this initiative to lose traction. While the amount of customers ordering takeout has increased, there is less emphasis on sustainability.<br/>Plastic is known for its harmful effects on the environment and the extreme length of time it takes to decompose. According to the International Union for Conservation of Nature (IUCN), almost 8 million tons of plastic end up in the oceans at an annual rate, threatening not only the safety of marine species but also human health. Modern food packaging materials have included a blend of synthetic ingredients, trickling into our daily lives and polluting the air, water, and land. Single-use plastic items slowly degrade into microplastics and can take up to hundreds of years to biodegrade.<br/>Due to COVID-19, restaurants have switched to takeout and delivery options to adapt to the new business environment and guidelines enforced by the Center of Disease Control (CDC) mandated guidelines. Some of these guidelines include: notices encouraging social distancing and mask-wearing, mandated masks for employees, and easy access to sanitary supplies. This cultural shift is motivating restaurants to search for a quick, cheap, and easy fix to adapt to the increased demand of take-out and delivery methods. This increases their plastic consumption of items such as plastic bags/paper bags, styrofoam containers, and beverage cups. Plastic is the most popular takeout material because of its price and durability as well as allowing for limited contamination and easy disposability.<br/>Almost all food products come in packaging and this, more often than not, is single-use. Food is the largest market out of all the packaging industry, maintaining roughly two-thirds of material going to food. The US Environmental Protection Agency reports that almost half of all municipal solid waste is made up of food and food packaging materials. In 2014, over 162 million tons of packaging material waste was generated in the states. This typically contains toxic inks and dyes that leach into groundwater and soil. When degrading, pieces of plastic absorb toxins like PCBs and pesticides, and then each piece will, in turn, release toxic chemicals like Bisphenol-A. Even before being thrown away, it causes negative effects for the environment. The creation of packaging materials uses many resources such as petroleum and chemicals and then releases toxic byproducts. Such byproducts include sludge containing contaminants, greenhouse gases, and heavy metal and particulate matter emissions. Unlike many other industries, plastic manufacturing has actually increased production. Demand has increased and especially in the food industry to keep things sanitary. This increase in production is reflective of the increase in waste. <br/>Although restaurants have implemented their own sustainable initiatives to combat their carbon footprint, the pandemic has unfortunately forced restaurants to digress. For example, Just Salad, a fast-food restaurant chain, incentivized customers with discounted meals to use reusable bowls which saved over 75,000 pounds of plastic per year. However, when the pandemic hit, the company halted the program to pivot towards takeout and delivery. This effect is apparent on an international scale. Singapore was in lock-down for eight weeks and during that time, 1,470 tons of takeout and food delivery plastic waste was thrown out. In addition, the Hong Kong environmental group Greeners Action surveyed 2,000 people in April and the results showed that people are ordering out twice as much as last year, doubling the use of plastic.<br/>However, is this surge of plastic usage necessary in the food industry or are there methods that can be used to reduce the amount of waste production? The COVID-19 pandemic caused a fracture in the food system’s supply chain, involving food, factory, and farm. This thesis will strive to tackle such topics by analyzing the supply chains of the food industry and identify areas for sustainable opportunities. These recommendations will help to identify areas for green improvement.

ContributorsDeng, Aretha (Co-author) / Tao, Adlar (Co-author) / Vargas, Cassandra (Co-author) / Printezis, Antonios (Thesis director) / Konopka, John (Committee member) / Department of Supply Chain Management (Contributor) / School of International Letters and Cultures (Contributor) / Department of Information Systems (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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What is being done to promote cultural sensitivity in healthcare settings? To find answers and solutions to the widespread deficit of cultural competence in the health care industry, this case study interviews a varied sample of five physicians consisting of three men and two women in clinical, academic, and administrative

What is being done to promote cultural sensitivity in healthcare settings? To find answers and solutions to the widespread deficit of cultural competence in the health care industry, this case study interviews a varied sample of five physicians consisting of three men and two women in clinical, academic, and administrative positions. The hypothesis was physicians do not receive cultural sensitivity training in medical school and as a result, they have to find other ways to learn about the cultures of their patients. None of the participants had received formal cultural competency training in medical school and all of them found methods to improve their cultural literacy. The study uncovered the cultural training physicians do receive is sporadic and inconsistent, which can cause some disconnect between education and real-life clinical practice. Many solutions to improve cultural competency in health care delivery are presented. The results of this exploratory research should be used to inspire future conversations about cultural competency in health care as well as the creation of support and educational services and materials to medical students and health care workers on improving cultural sensitivity in clinical practice.

ContributorsWilson, Diane Kathleen (Author) / Cortese, Denis (Thesis director) / Estevez, Dulce (Committee member) / School of International Letters and Cultures (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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Much of Nepal lacks access to clean drinking water, and many water sources are contaminated with arsenic at concentrations above both World Health Organization and local Nepalese guidelines. While many water treatment technologies exist, it is necessary to identify those that are easily implementable in developing areas. One simple treatment

Much of Nepal lacks access to clean drinking water, and many water sources are contaminated with arsenic at concentrations above both World Health Organization and local Nepalese guidelines. While many water treatment technologies exist, it is necessary to identify those that are easily implementable in developing areas. One simple treatment that has gained popularity is biochar—a porous, carbon-based substance produced through pyrolysis of biomass in an oxygen-free environment. Arizona State University’s Engineering Projects in Community Service (EPICS) has partnered with communities in Nepal in an attempt to increase biochar production in the area, as it has several valuable applications including water treatment. Biochar’s arsenic adsorption capability will be investigated in this project with the goal of using the biochar that Nepalese communities produce to remove water contaminants. It has been found in scientific literature that biochar is effective in removing heavy metal contaminants from water with the addition of iron through surface activation. Thus, the specific goal of this research was to compare the arsenic adsorption disparity between raw biochar and iron-impregnated biochar. It was hypothesized that after numerous bed volumes pass through a water treatment column, iron from the source water will accumulate on the surface of raw biochar, mimicking the intentionally iron-impregnated biochar and further increasing contaminant uptake. It is thus an additional goal of this project to compare biochar loaded with iron through an iron-spiked water column and biochar impregnated with iron through surface oxidation. For this investigation, the biochar was crushed and sieved to a size between 90 and 100 micrometers. Two samples were prepared: raw biochar and oxidized biochar. The oxidized biochar was impregnated with iron through surface oxidation with potassium permanganate and iron loading. Then, X-ray fluorescence was used to compare the composition of the oxidized biochar with its raw counterpart, indicating approximately 0.5% iron in the raw and 1% iron in the oxidized biochar. The biochar samples were then added to batches of arsenic-spiked water at iron to arsenic concentration ratios of 20 mg/L:1 mg/L and 50 mg/L:1 mg/L to determine adsorption efficiency. Inductively coupled plasma mass spectrometry (ICP-MS) analysis indicated an 86% removal of arsenic using a 50:1 ratio of iron to arsenic (1.25 g biochar required in 40 mL solution), and 75% removal with a 20:1 ratio (0.5 g biochar required in 40 mL solution). Additional samples were then inserted into a column process apparatus for further adsorption analysis. Again, ICP-MS analysis was performed and the results showed that while both raw and treated biochars were capable of adsorbing arsenic, they were exhausted after less than 70 bed volumes (234 mL), with raw biochar lasting 60 bed volumes (201 mL) and oxidized about 70 bed volumes (234 mL). Further research should be conducted to investigate more affordable and less laboratory-intensive processes to prepare biochar for water treatment.

ContributorsLaird, Ashlyn (Author) / Schoepf, Jared (Thesis director) / Westerhoff, Paul (Committee member) / Chemical Engineering Program (Contributor) / School of International Letters and Cultures (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
Description

A journalistic, first-person narrative going through the lessons learned from travel. The story is complemented by a series of photos from childhood to the present all uploaded to a Wix-based website.

Created2021-05
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The purpose of this research is to exploit the neglect of specific populations and diseases in Latin America through an epidemiological literature review. As a small part of a larger publication, the foci of this research was the infectious disease, helminthiasis. Using manually indexed abstracts from the National Library of

The purpose of this research is to exploit the neglect of specific populations and diseases in Latin America through an epidemiological literature review. As a small part of a larger publication, the foci of this research was the infectious disease, helminthiasis. Using manually indexed abstracts from the National Library of Medicine database in PubMed, 4,594 papers were synthesized and then processed for further review. Of those papers, 29 provided information about helminths in indigenous populations. These papers were reviewed and used in prevalence data extraction and variable analysis. The main conclusion was to reveal the fact that from an entire health database less than 30 papers provided information about the persistence of helminths in indigenous communities of Latin America. Not only that but the few papers that could be analyzed had consistently high prevalence ratios.

ContributorsGregory, Cassandre June (Author) / Hurtado, Ana Magdalena (Thesis director) / Estevez, Dulce (Committee member) / School of Life Sciences (Contributor) / School of Human Evolution & Social Change (Contributor, Contributor) / School of International Letters and Cultures (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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The microbiome and the immune system are known to work in conjunction to modulate the clearance of pathogens and tolerance of beneficial microbes. A growing area of research seeks to study the potential extent of the involvement of the microbiome in modulating and supporting the immune system during acute allograft

The microbiome and the immune system are known to work in conjunction to modulate the clearance of pathogens and tolerance of beneficial microbes. A growing area of research seeks to study the potential extent of the involvement of the microbiome in modulating and supporting the immune system during acute allograft rejection. It has been hypothesized that the localized microbiota in each organ produce metabolites that instigate inflammatory immune responses, but whether microbiota interactions precipitate acute allograft rejection is unknown. Therefore, this study focuses on microbiome shifts in the gut and kidney after inducing acute renal transplant rejection in order to implicate gut dysbiosis as a precursor or supporter of allograft rejection. This study also subsequently explores the use of an immune-modulating protein in order to determine differences in the outcome of transplant rejection and potential differences in intestinal microbial load. This experiment sought to induce rejection in BALB/c mice through the use of C57BL/6 mouse renal slivers. Microbiome abundance was analyzed in all experimental groups. Understanding the role of the microbiome in transplant rejection has vast clinical implications and has the potential to enhance pre- and post-operative treatment, and immune management and quality of life following organ transplant.

ContributorsKokott, Kristiana Tara (Author) / Lim, Efrem (Thesis director) / Lucas, Alexandra (Committee member) / School of International Letters and Cultures (Contributor) / School of Life Sciences (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2021-05