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- Creators: School of Molecular Sciences
- Creators: Department of Supply Chain Management
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For my honors thesis research project, I was interested to learn more about why not everyone purchases fair trade products. The goal of this project is to research more about if there is a lack of awareness regarding fair trade products? And if there were more awareness would people seek out fairly traded products? This paper highlights what I learned about fair trade products as well as what I did to educate people in my community on fair trade.
In cold chain tracking systems, accuracy and flexibility across different temperatures ranges plays an integral role in monitoring biospecimen integrity. However, while two common cold chain tracking systems are currently available (electronic and physics/chemical), there is not an affordable cold chain tracking mechanism that can be applied to a variety of temperatures while maintaining accuracy for individual vials. Hence, our lab implemented our understanding of biochemical reaction kinetics to develop a new cold chain tracking mechanism using the permanganate/oxalic acid reaction. The permanganate/oxalic acid reaction is characterized by the reduction of permanganate (MnVII) to Mn(II) with Mn(II)-autocatalyzed oxidation of oxalate to CO2, resulting in a pink to colorless visual indicator change when the reaction system is not in the solid state (i.e., frozen or vitrified). Throughout our research, we demonstrate, (i) Improved reaction consistency and accuracy along with extended run times with the implementation of a nitric acid-based labware washing protocol, (ii) Simulated reaction kinetics for the maximum length reaction and 60-minute reaction based on previously developed MATLAB scripts (iii) Experimental reaction kinetics to verify the simulated MATLAB maximum and 60-minute reactions times (iv) Long-term stability of the permanganate/oxalic acid reaction with water or eutectic solutions of sodium perchlorate and magnesium perchlorate at -80°C (v) Reaction kinetics with eutectic solvents, sodium perchlorate and magnesium perchlorate, at 25°C, 4°C, and -8°C (vi) Accelerated reaction kinetics after the addition of varying concentrations of manganese perchlorate (vii) Reaction kinetics of higher concentration reaction systems (5x and 10x; for darker colors), at 25°C (viii) Long-term stability of the 10x higher concentration reaction at -80°C.
An effort to experiment on the novel Usutu virus in pure in silico methods was made to determine conformational changes with non polar point mutations in the amino acid sequence. The first method consisted of creating a Python program to exhaustively identify codons, amino acids, and dinucleotide bridges & nonbridges, including viral characteristics defined by Mollentze in 2021. The second method consisted of creating point mutations to non polar amino acids in deemed key sites of the Usutu virus envelope protein and finding the RMSD from the original structure. This resulted in one of two outcomes - either the experiment showed that the Usutu virus envelope protein is highly resistant to point mutations or in silico methods are inconsistent and biased, leading to inaccuracy.
Iron Cycling May Lower Methane Fluxes at an Impounded Marsh: Evidence from the Herring River Estuary
The Supply Chain of a company is the most critical component of a business as it directly impacts a company’s ability to deliver products/services to customers is a timely, cost effective method. With this amount of importance, a resilient supply chain is pivotal for positive future earnings in each successive quarter. Two pivotal metrics to gauge a Supply Chain include Production Delays and Excess Inventory. Through in-depth analysis, it was found that these metrics had caused abnormal amounts of price volatility with a stock’s performance. Understanding these metrics, the impact and lesson that COVID had taught, and analyzing earnings transcripts of publicly traded company’s demonstrates the use of Supply Chain health in comparison to company performance. This thesis aims to examine how a company's supply chain affects its performance, by analyzing different metrics and disruptions that have caused significant volatility in the stock market. The objective is to help investors maximize their profitability or reduce their risk by identifying the key factors that impact a company's supply chain.