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The following paper is a comparison between the Mercato di Sant’Ambrogio (Sant’Ambrogio Market) in Florence, Italy and the Open Air Farmers’ Market in Phoenix, Arizona. Farmers’ markets, such as these, serve to rekindle a relationship with food that over time has been lost, particularly due to the green revolution, globalisation,

The following paper is a comparison between the Mercato di Sant’Ambrogio (Sant’Ambrogio Market) in Florence, Italy and the Open Air Farmers’ Market in Phoenix, Arizona. Farmers’ markets, such as these, serve to rekindle a relationship with food that over time has been lost, particularly due to the green revolution, globalisation, and the mechanization of agriculture. In addition, farmers’ markets serve to foster relationships between community members and farmers, and they are an important element of a movement to create food sovereignty within local communities. Food sovereignty gives people the right to decide their food choices. In our modern system where many agricultural decisions are made by the government or large corporations, reclaiming food sovereignty is a larger effort to take back control of personal rights, individual health and the health of the environment.
Using Sant’Ambrogio and Open Air as case studies for the research, this paper provides insight on the degree of impact that local farmers’ markets can have on creating food sovereignty within communities; and how pre-existing factors and negative forces diminish the benefits of farmers’ markets and local food movements. Among many, some of these negative forces include the effects of social and cultural pressures that promote fast food and convenience; a broken agricultural system controlled by monopoly companies; industrial food items priced cheaper than small farmers can compete with; and an underscore of unethical behavior across all sectors (including organic and local) that inhibit honest farmers from making enough profit to survive.
The comparison between Sant’Ambrogio and Open Air Market indicates that big agriculture undermines the success of local farming movements in both countries, but Phoenix can still learn from the movement in Florence, which is rooted in a deep history of outdoor markets and rich food culture. Italy is fortunate in terms of their agriculture capacity because their climate allows for a diverse variety of crops; while Arizona does not have the same agricultural capacity as the Mediterranean climate of Italy, it is still valuable to mimic the network of local food systems that Italy has. In order to do so, Phoenician consumers should take advantage of the food that grows locally and then supplement it with more diverse crops from other areas of Arizona or the southwest.
The Open Air Market in Phoenix currently does not play an important role in the food system except for helping people to relate community and socialization to food. Transparency, communication and education are required to actually increase the success of small local farmers and to help the Open Air Market play a real role in the local food movement and the establishment of food sovereignty.
ContributorsAnderson, Layla (Author) / Vitullo, Juliann (Thesis director) / McGregor, Joan (Committee member) / School of Sustainability (Contributor) / Dean, W.P. Carey School of Business (Contributor) / Department of Management and Entrepreneurship (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
Patients with type 2 diabetes mellitus experience a slower healing process and poor osteointegration, making it difficult for them to heal properly after a bone fracture. This study aims to compare the proliferation and differentiation of human mesenchymal stromal cells at different glucose concentrations, as well as with an advanced

Patients with type 2 diabetes mellitus experience a slower healing process and poor osteointegration, making it difficult for them to heal properly after a bone fracture. This study aims to compare the proliferation and differentiation of human mesenchymal stromal cells at different glucose concentrations, as well as with an advanced glycated end-product (AGE) concentration, to mimic a healthy, prediabetic, and diabetic environment in an in vitro model over several experiments. Each experiment was composed of treatment groups in either growth or osteogenic media, with varying levels of glucose concentration or an advanced glycated end-product concentration. The treatment groups were cultured in 24 well plates over 28 days with staining of FITC-maleimide, DAPI, or alkaline phosphatase conducted at varying time points. The plates were imaged, then analyzed in ImageJ and GraphPad Prism. The study supports that at 28 days in culture, the more glucose added to osteogenic media treatment groups, the lower the nuclear count. At 14 days the same is true of growth media treatment groups, though the trend does not persist until 28 days. It does not seem that cell surface area of osteogenic groups, and growth media treatment groups was affected by glucose level. At 14 days, the alkaline phosphatase expression was unaffected by glucose level. However, at the 28 day time point the higher the glucose level of osteogenic treatment groups, the less expression of alkaline phosphatase. The effect of the added AGE concentration on hMSC osteogenesis was inconclusive. Overall, this study enhanced understanding of the role that glucose and AGEs play in the bone healing process for diabetic patients, allowing for future improvements of biomaterials and engineered tissue.
ContributorsMoya, Adriana Allyssa (Author) / Holloway, Julianne (Thesis director) / Fumasi, Fallon (Committee member) / Dean, W.P. Carey School of Business (Contributor) / Chemical Engineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
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Description

This study examined crayfish diet within varying hydrologic environment in lotic systems using stable isotope analysis of crayfish and basal resources to add depth to previous findings. Crayfish are numerous and are omnivorous, opportunistic feeders, feeding on invertebrates, vegetation and detritus. Arizona streams stand apart from the Eastern and Northwestern

This study examined crayfish diet within varying hydrologic environment in lotic systems using stable isotope analysis of crayfish and basal resources to add depth to previous findings. Crayfish are numerous and are omnivorous, opportunistic feeders, feeding on invertebrates, vegetation and detritus. Arizona streams stand apart from the Eastern and Northwestern aquatic ecosystems of the United States because Arizona has no native crayfish species. Two species have been introduced and become widely established in Arizona (Orconectes virilis and Procambarus clarkii), with concern for further introduction of crayfish species and more information on how these two species impact the native species in the streams is needed. Previous studies have focused on crayfish abundance with hydrologic variation and crayfish diets within a lentic system, but few have focused on how the diet of consumers varies with hydrologic variability. Crayfish are hardy and have a dramatically increasing population within Arizona and therefore inhabit systems with a wide range of hydrologic variability which may contribute to spatial variability. The results show that crayfish diets do show a significant level of seasonal variation in some study locations, in both C source and trophic level. Hydrologic variation was also shown to impact crayfish diet at several study sites, with increasing magnitude of event (both floods and droughts) correlating with a change toward more aquatic C sources and lower trophic position in several of the study sites. In some locations, the correlation was not as strong with variation and diet change and showed less change in C source and rather showed an increase in trophic position.

ContributorsThompson, Sara Nicole (Author) / Sabo, John L. (Thesis director) / Grimm, Nancy (Committee member) / Baruch, Ethan M. (Committee member) / School of Geographical Sciences and Urban Planning (Contributor) / Dean, W.P. Carey School of Business (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
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Description
In cancer, various genetic and epigenetic alterations cause cancer cells to hyperproliferate and to bypass the survival and migration mechanisms that typically regulate healthy cells. The focal adhesion kinase (FAK) gene produces FAK, a protein that has been implicated in tumor progression in various cancers. Compared with normal tissue counterparts,

In cancer, various genetic and epigenetic alterations cause cancer cells to hyperproliferate and to bypass the survival and migration mechanisms that typically regulate healthy cells. The focal adhesion kinase (FAK) gene produces FAK, a protein that has been implicated in tumor progression in various cancers. Compared with normal tissue counterparts, FAK is overexpressed in many cancers. FAK is therefore a promising cancer drug target due to its demonstrated role in cancer invasion and metastasis and inhibition of FAK is important to achieve an optimal tumor response. Small molecule FAK inhibitors have been shown to decrease tumor growth and metastasis in several preclinical trials. However, these inhibitors focus narrowly on the enzymatic portion of FAK and neglect its scaffolding function, leaving FAK’s scaffolding of oncogenic drivers intact. Paxillin, a major focal adhesion-associated protein, binds to FAK, enabling it to localize to focal adhesions, and this is essential for FAK’s activation and function. Therefore, disrupting the protein-protein interaction between FAK and paxillin has been hypothesized to prevent tumor progression. The binding of FAK to paxillin at its focal adhesion targeting (FAT) domain is mediated by two highly conserved leucine-rich sequences, the leucine-aspartic acid (LD) motifs LD2 and LD4. The purpose of this project was to develop novel stapled LD2 peptide analogs that target the protein-protein interaction of FAT to LD2. Peptide stapling was performed to enhance the pharmacological performance of the LD2 peptide analogs. Based on the native LD2 peptide sequence, stapled LD2 peptide analogs were developed with the intent to improve efficacy of cell permeability, while maintaining or improving FAK binding. The LD2 peptide analogs were characterized via surface plasmon resonance, fluorescence polarization, immunofluorescence, and circular dichroism spectroscopy. Successful LD2 stapled peptide analogs can be therapeutically relevant inhibitors of the FAT-LD2 protein-protein interaction in cancer and have the potential for greater efficacy in FAK inhibition, proteolytic resistance, and cell permeability, which is key in preventing tumor progression in cancer.
ContributorsNott, Rohini (Author) / Gould, Ian R. (Thesis director) / Marlowe, Timothy A. (Committee member) / Cance, William G. (Committee member) / School of Life Sciences (Contributor) / Dean, W.P. Carey School of Business (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
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Description
Long-acting reversible contraceptive methods (LARCs) are a class of highly effective contraceptive methods that includes the hormonal IUD, the copper IUD and the Implant. Despite pregnancy prevention prevailing as the primary motivation for contraceptive use and the pill’s lower effectiveness in actual use, the birth control pill is the most

Long-acting reversible contraceptive methods (LARCs) are a class of highly effective contraceptive methods that includes the hormonal IUD, the copper IUD and the Implant. Despite pregnancy prevention prevailing as the primary motivation for contraceptive use and the pill’s lower effectiveness in actual use, the birth control pill is the most commonly used method among people aged 18-24 years old. Through surveying 300 undergraduate female students from Arizona State University, we studied the impact of a visual resource, tiering methods by effectiveness, on the revision of likelihood of use for any contraceptive method and for LARCs in particular. We found that the visual resource significantly impacted likelihood of LARC use and that participants who cited pregnancy prevention as their only motivation for using a contraceptive method revised their likelihood of LARC use significantly more than participants who cited only hormonal benefit or more than one motivation.
ContributorsDries, Ellen Katherine (Author) / Zafar, Basit (Thesis director) / Green, Ellen (Committee member) / School of Mathematical and Statistical Sciences (Contributor) / Dean, W.P. Carey School of Business (Contributor) / Department of Economics (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
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This paper analyzes responses to a survey using a modified fourfold pattern of preference to determine if implicit information, once made explicit, is practically significant in nudging irrational decision makers towards more rational decisions. Respondents chose between two scenarios and an option for indifference for each of the four questions

This paper analyzes responses to a survey using a modified fourfold pattern of preference to determine if implicit information, once made explicit, is practically significant in nudging irrational decision makers towards more rational decisions. Respondents chose between two scenarios and an option for indifference for each of the four questions from the fourfold pattern with expected value being implicit information. Then respondents were asked familiarity with expected value and given the same four questions again but with the expected value for each scenario then explicitly given. Respondents were asked to give feedback if their answers had changed and if the addition of the explicit information was the reason for that change. Results found the addition of the explicit information in the form of expected value to be practically significant with ~90% of respondents who changed their answers giving that for the reason. In the implicit section of the survey, three out of four of the questions had a response majority of lower expected value answers given compared to the alternative. In the explicit section of the survey, all four questions achieved a response majority of higher expected value answers given compared to the alternative. In moving from the implicit to the explicit section, for each question, the scenario with lower expected value experienced a decrease in percentage of responses, and the scenario with higher expected value and indifference between the scenarios both experienced an increase in percentage of responses.
ContributorsJohnson, Matthew (Author) / Goegan, Brian (Thesis director) / Foster, William (Committee member) / School of Sustainability (Contributor) / Economics Program in CLAS (Contributor) / Dean, W.P. Carey School of Business (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
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This study examines four films from Sollosi’s 2018 list of the top fifteen grossing box office romantic comedies. The films analyzed include Crazy Rich Asians, The Proposal, My Big Fat Greek Wedding, and Pretty Woman whose release dates range from 1990 to 2018. This study observes how these films seemingly

This study examines four films from Sollosi’s 2018 list of the top fifteen grossing box office romantic comedies. The films analyzed include Crazy Rich Asians, The Proposal, My Big Fat Greek Wedding, and Pretty Woman whose release dates range from 1990 to 2018. This study observes how these films seemingly defy stereotypical gender roles, but more often reaffirm them by incorporating stereotypical characteristics. Stereotypical gender roles are expectations of gender that is based off of one’s sex, and stereotypical meaning a widely held and fixed idea or image of a person (Krijnen & Bauwel, 2015).
It is problematic for these films to be reaffirming stereotypical gender roles because of the influence forms of mass media can have on society. According to Hammer (2009), society learns what acceptable and normal roles are through mass media. The films in this study are not only portraying to society what exactly women’s roles are but also how women should be fulfilling those roles. Hall claims, “Stereotyping reduces people to a few, simple, essential characteristics, which are represented as fixed by Nature” (as cited in Krijnen & Bauwel, 2015, p.44). When films place women in stereotypical roles, and perpetuate the idea that the roles are fixed by Nature, they make it difficult for women to transition out of those roles in future films and, in turn, in life. In this study, categories of analysis derived from previous literature reviews as well as observation are used to identify specific roles that are being portrayed repeatedly throughout each film.
ContributorsGargano, Abbey (Author) / Barca, Lisa (Thesis director) / Mack, Robert (Committee member) / Dean, W.P. Carey School of Business (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
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This study examines the intersectionality of mental health and education, with an emphasis on resources and awareness for elementary school teachers. It starts with a review of mental health awareness in society, particularly in regard to social stigma and its associated effects. I then discuss the existing resources, teaching methods,

This study examines the intersectionality of mental health and education, with an emphasis on resources and awareness for elementary school teachers. It starts with a review of mental health awareness in society, particularly in regard to social stigma and its associated effects. I then discuss the existing resources, teaching methods, and third party interventions which address mental health awareness and care within elementary schools. Within this context, the research supports the strong influence of teachers’ behaviors and perceivable attitudes on students. However, despite the identification of teachers playing a significant role in the availability of mental health resources for students, existing studies rarely addresses the necessity of mental health awareness and care to optimize teacher capacity and counteract occupational stress. The study examines the current approach and challenges of an elementary school that has expressed interest in creating a culture of care, characterized by mental health awareness and resources that support teachers within the school environment. After identifying the key mental health concerns of the school’s stakeholders, I propose a custom program of self-care and mental health awareness to support the current work culture. The study concludes with examination of implementation strategies for the school, as well as implications for future mental health awareness in similar settings.
ContributorsGiles, Emma (Author) / Johnston, Erik W., 1977- (Thesis director) / Hinrichs, Margaret (Committee member) / Desch, Timothy (Committee member) / Dean, W.P. Carey School of Business (Contributor, Contributor) / School of Public Affairs (Contributor) / Department of Management and Entrepreneurship (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
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This case study is an analysis about the crisis communication tactics that were taken by Futbol Club Barcelona on September 20th and October 1st in regards to the events related to the Catalan Independence Referendum. This paper will analyze the Attribution Theory and what factors to consider when choosing a

This case study is an analysis about the crisis communication tactics that were taken by Futbol Club Barcelona on September 20th and October 1st in regards to the events related to the Catalan Independence Referendum. This paper will analyze the Attribution Theory and what factors to consider when choosing a crisis response strategy. The case study will also analyze the events that took place leading up to and the day the vote took place in Barcelona. It is important to note that this analysis will be done from a general soccer fan’s point of view.
I will begin with a literature review that covers the different crisis communication theories and approaches that fall under the Attribution Theory. I will then discuss the background behind the crisis I am analyzing. This section will include history about the Catalan Independence Movement, the relationship between Futbol Club Barcelona and Catalan Nationalism, and FC Barcelona relationship and involvement with the Independence Referendum. Lastly, I will analyze FC Barcelona’s crisis communication methods and how it was received by the public surrounding the events that took place on and before October 1st 2017.
ContributorsMeraz, Alana Celeste (Author) / Kassing, Jeffrey (Thesis director) / Bagnato, Andrew (Committee member) / School of Community Resources and Development (Contributor) / Department of Marketing (Contributor) / Dean, W.P. Carey School of Business (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
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With the increase in women’s professional sports teams and the burst in female sport participation since Title IX, we might expect increased media attention on women’s sports. However, female athletes’ journey for equality is still a work in progress. Women in sports are underrepresented in the volume and type of

With the increase in women’s professional sports teams and the burst in female sport participation since Title IX, we might expect increased media attention on women’s sports. However, female athletes’ journey for equality is still a work in progress. Women in sports are underrepresented in the volume and type of sports coverage they receive. They are generally represented in media forms, such as magazines and advertising, that focus on their bodies as sexual objects rather than their abilities as athletes. This paper will explore how female athletes are portrayed not only less and in less athletic contexts than male athletes, but also in ways that support the patriarchal dominance that is prevalent in American sports. By examining print media, advertising, televised sports coverage and social media, this paper demonstrates the system of male hegemony that underlies American sports.
ContributorsEvans, Rebekah (Author) / Barca, Lisa (Thesis director) / Dove-Viebahn, Aviva (Committee member) / Dean, W.P. Carey School of Business (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05