Matching Items (338)
Description
The aim of this project was to conduct an investigation of the cosmetic industry, particularly the field encompassing Botox and dermal fillers. The research helped to identify the various types of fillers used in the market as well as to explore the potential advantages of mechanical injectors within the field. This research and an industry analysis was further used to investigate the necessary components that would best accommodate the patent for a mechanical hand-held injector for the injection of dermal fillers.
ContributorsJames, Merine (Author) / Martin, Thomas (Thesis director) / Devine, John (Committee member) / College of Integrative Sciences and Arts (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
Developments in commercial genetic testing have made it possible for people to find out a wealth of information that was previously difficult or impossible to obtain. Genetic testing is a novel solution to the adaptive problem of paternal uncertainty. We hypothesized that participants in the control condition would have greater interest in their paternal genetic information than their maternal genetic information and that participants who were cued to their dissimilarities with their father would seek out genetic information regarding their paternal side of the family above all other conditions. Neither of the two tested hypotheses were supported by the data. Analyses of several variables suggest that the manipulation did work to enhance perceptions of similarity and dissimilarity to parents, that participants were paying attention, and that the dependent variables were sensitive. Some incidental findings suggest that feelings of similarity, rather than dissimilarity, to father are related to interest in learning about paternal genealogy.
ContributorsSabree, Kaelyn Adele (Author) / Kenrick, Douglas (Thesis director) / Corbin, William (Committee member) / Neuberg, Steven (Committee member) / Ko, Ahra (Committee member) / Department of Psychology (Contributor) / College of Integrative Sciences and Arts (Contributor) / Barrett, The Honors College (Contributor)
Created2020-12
Description
The use of Artificial Intelligence in assistive systems is growing in application and efficiency. From self-driving cars, to medical and surgical robots and industrial tasked unsupervised co-robots; the use of AI and robotics to eliminate human error in high-stress environments and perform automated tasks is something that is advancing society’s status quo. Not only has the understanding of co-robotics exploded in the industrial world, but in research as well. The National Science Foundation (NSF) defines co-robots as the following: “...a robot whose main purpose is to work with people or other robots to accomplish a goal” (NSF, 1). The latest iteration of their National Robotics Initiative, NRI-2.0, focuses on efforts of creating co-robots optimized for ‘scalability, customizability, lowering barriers to entry, and societal impact’(NSF, 1). While many avenues have been explored for the implementation of co-robotics to create more efficient processes and sustainable lifestyles, this project’s focus was on societal impact co-robotics in the field of human safety and well-being. Introducing a co-robotics and computer vision AI solution for first responder assistance would help bring awareness and efficiency to public safety. The use of real-time identification techniques would create a greater range of awareness for first responders in high-stress situations. A combination of environmental features collected through sensors (camera and radar) could be used to identify people and objects within certain environments where visual impairments and obstructions are high (eg. burning buildings, smoke-filled rooms, ect.). Information about situational conditions (environmental readings, locations of other occupants, etc.) could be transmitted to first responders in emergency situations, maximizing situational awareness. This would not only aid first responders in the evaluation of emergency situations, but it would provide useful data for the first responder that would help materialize the most effective course of action for said situation.
ContributorsScott, Kylel D (Author) / Benjamin, Victor (Thesis director) / Liu, Xiao (Committee member) / Engineering Programs (Contributor) / College of Integrative Sciences and Arts (Contributor) / Department of Information Systems (Contributor) / Barrett, The Honors College (Contributor)
Created2020-12
Description
Approximately 15,000 children die every day due to preventable illnesses (World Health Organization, 2016, 2017). Most of these deaths have been concentrated in developing countries and specifically in Sub-Saharan Africa, South Asia and to a lesser extent in Central Asia. Many studies have analyzed determinants of infant mortality rates across regions of South Asia. Despite neighboring South Asia, reasons for infant mortality in Central Asia do not seem to be as heavily researched. To investigate whether there are differences in the risk factors for infant mortality between South Asia and Central Asia, I analyzed data on 557,089 women and 1,272,916 children from Demographic Health Surveys and Multiple Indicator Cluster Surveys in 5 Central Asian (Azerbaijan, Kazakhstan, Kyrgyzstan, Uzbekistan, Tajikistan) and 5 South Asian (Afghanistan, Bangladesh, India, Nepal, Pakistan) countries. Binary logistic regression predicted whether a child was alive based on a number of maternal and child characteristics, including maternal age, maternal education, maternal residence, place of delivery, wealth, open defecation, prenatal care, and vaccinations. There were similarities along with differences in child survival outcomes between Central Asia and South Asia. Maternal age, maternal education, and the DPT 3 vaccination appeared to have protective effects on child survival rates in both Central Asia and South Asia whereas delivery outside of the hospital and open defecation have negative effects on child survival outcomes. Tetanus, polio 1, and the BCG vaccinations appeared to have a more pronounced positive effect on child survival in Central Asia whereas measles and polio 3 appear to have a more pronounced positive effect in South Asia. Wealth also appeared to have a greater protective effect in South Asia as opposed to Central Asia. More research needs to be conducted to elaborate on reasons for why there are differences between Central Asia and South Asia.
ContributorsAlam, Mariam (Author) / Hrsuchka, Daniel (Thesis director) / Gaughan, Monica (Committee member) / College of Integrative Sciences and Arts (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
Premise of the study: Land-plant plastid genomes have only rarely undergone significant changes in gene content and order. Thus, discovery of additional examples adds power to tests for causes of such genome-scale structural changes.
Methods: Using next-generation sequence data, we assembled the plastid genome of saguaro cactus and probed the nuclear genome for transferred plastid genes and functionally related nuclear genes. We combined these results with available data across Cactaceae and seed plants more broadly to infer the history of gene loss and to assess the strength of phylogenetic association between gene loss and loss of the inverted repeat (IR).
Key results: The saguaro plastid genome is the smallest known for an obligately photosynthetic angiosperm (∼113 kb), having lost the IR and plastid ndh genes. This loss supports a statistically strong association across seed plants between the loss of ndh genes and the loss of the IR. Many nonplastid copies of plastid ndh genes were found in the nuclear genome, but none had intact reading frames; nor did three related nuclear-encoded subunits. However, nuclear pgr5, which functions in a partially redundant pathway, was intact.
Conclusions: The existence of an alternative pathway redundant with the function of the plastid NADH dehydrogenase-like complex (NDH) complex may permit loss of the plastid ndh gene suite in photoautotrophs like saguaro. Loss of these genes may be a recurring mechanism for overall plastid genome size reduction, especially in combination with loss of the IR.
Methods: Using next-generation sequence data, we assembled the plastid genome of saguaro cactus and probed the nuclear genome for transferred plastid genes and functionally related nuclear genes. We combined these results with available data across Cactaceae and seed plants more broadly to infer the history of gene loss and to assess the strength of phylogenetic association between gene loss and loss of the inverted repeat (IR).
Key results: The saguaro plastid genome is the smallest known for an obligately photosynthetic angiosperm (∼113 kb), having lost the IR and plastid ndh genes. This loss supports a statistically strong association across seed plants between the loss of ndh genes and the loss of the IR. Many nonplastid copies of plastid ndh genes were found in the nuclear genome, but none had intact reading frames; nor did three related nuclear-encoded subunits. However, nuclear pgr5, which functions in a partially redundant pathway, was intact.
Conclusions: The existence of an alternative pathway redundant with the function of the plastid NADH dehydrogenase-like complex (NDH) complex may permit loss of the plastid ndh gene suite in photoautotrophs like saguaro. Loss of these genes may be a recurring mechanism for overall plastid genome size reduction, especially in combination with loss of the IR.
ContributorsSanderson, Michael J. (Author) / Copetti, Dario (Author) / Burquez, Alberto (Author) / Bustamante, Enriquena (Author) / Charboneau, Joseph L. M. (Author) / Eguiarte, Luis E. (Author) / Kumar, Sudhir (Author) / Lee, Hyun Oh (Author) / Lee, Junki (Author) / McMahon, Michelle (Author) / Steele, Kelly (Author) / Wing, Rod (Author) / Yang, Tae-Jin (Author) / Zwickl, Derrick (Author) / Wojciechowski, Martin (Author) / College of Integrative Sciences and Arts (Contributor) / College of Liberal Arts and Sciences (Contributor) / School of Life Sciences (Contributor)
Created2015-07-01
Description
Mathematical epidemiology, one of the oldest and richest areas in mathematical biology, has significantly enhanced our understanding of how pathogens emerge, evolve, and spread. Classical epidemiological models, the standard for predicting and managing the spread of infectious disease, assume that contacts between susceptible and infectious individuals depend on their relative frequency in the population. The behavioral factors that underpin contact rates are not generally addressed. There is, however, an emerging a class of models that addresses the feedbacks between infectious disease dynamics and the behavioral decisions driving host contact. Referred to as “economic epidemiology” or “epidemiological economics,” the approach explores the determinants of decisions about the number and type of contacts made by individuals, using insights and methods from economics. We show how the approach has the potential both to improve predictions of the course of infectious disease, and to support development of novel approaches to infectious disease management.
ContributorsPerrings, Charles (Author) / Castillo-Chavez, Carlos (Author) / Chowell-Puente, Gerardo (Author) / Daszak, Peter (Author) / Fenichel, Eli P. (Author) / Finnoff, David (Author) / Horan, Richard D. (Author) / Kilpatrick, A. Marm (Author) / Kinzig, Ann (Author) / Kuminoff, Nicolai (Author) / Levin, Simon (Author) / Morin, Benjamin (Author) / Smith, Katherine F. (Author) / Springborn, Michael (Author) / Simon M. Levin Mathematical, Computational and Modeling Sciences Center (Contributor) / College of Liberal Arts and Sciences (Contributor) / School of Life Sciences (Contributor) / School of Human Evolution and Social Change (Contributor) / W.P. Carey School of Business (Contributor) / Economics (Contributor) / Julie Ann Wrigley Global Institute of Sustainability (Contributor)
Created2015-12-01
Description
Background
Seroepidemiological studies before and after the epidemic wave of H1N1-2009 are useful for estimating population attack rates with a potential to validate early estimates of the reproduction number, R, in modeling studies.
Methodology/Principal Findings
Since the final epidemic size, the proportion of individuals in a population who become infected during an epidemic, is not the result of a binomial sampling process because infection events are not independent of each other, we propose the use of an asymptotic distribution of the final size to compute approximate 95% confidence intervals of the observed final size. This allows the comparison of the observed final sizes against predictions based on the modeling study (R = 1.15, 1.40 and 1.90), which also yields simple formulae for determining sample sizes for future seroepidemiological studies. We examine a total of eleven published seroepidemiological studies of H1N1-2009 that took place after observing the peak incidence in a number of countries. Observed seropositive proportions in six studies appear to be smaller than that predicted from R = 1.40; four of the six studies sampled serum less than one month after the reported peak incidence. The comparison of the observed final sizes against R = 1.15 and 1.90 reveals that all eleven studies appear not to be significantly deviating from the prediction with R = 1.15, but final sizes in nine studies indicate overestimation if the value R = 1.90 is used.
Conclusions
Sample sizes of published seroepidemiological studies were too small to assess the validity of model predictions except when R = 1.90 was used. We recommend the use of the proposed approach in determining the sample size of post-epidemic seroepidemiological studies, calculating the 95% confidence interval of observed final size, and conducting relevant hypothesis testing instead of the use of methods that rely on a binomial proportion.
Seroepidemiological studies before and after the epidemic wave of H1N1-2009 are useful for estimating population attack rates with a potential to validate early estimates of the reproduction number, R, in modeling studies.
Methodology/Principal Findings
Since the final epidemic size, the proportion of individuals in a population who become infected during an epidemic, is not the result of a binomial sampling process because infection events are not independent of each other, we propose the use of an asymptotic distribution of the final size to compute approximate 95% confidence intervals of the observed final size. This allows the comparison of the observed final sizes against predictions based on the modeling study (R = 1.15, 1.40 and 1.90), which also yields simple formulae for determining sample sizes for future seroepidemiological studies. We examine a total of eleven published seroepidemiological studies of H1N1-2009 that took place after observing the peak incidence in a number of countries. Observed seropositive proportions in six studies appear to be smaller than that predicted from R = 1.40; four of the six studies sampled serum less than one month after the reported peak incidence. The comparison of the observed final sizes against R = 1.15 and 1.90 reveals that all eleven studies appear not to be significantly deviating from the prediction with R = 1.15, but final sizes in nine studies indicate overestimation if the value R = 1.90 is used.
Conclusions
Sample sizes of published seroepidemiological studies were too small to assess the validity of model predictions except when R = 1.90 was used. We recommend the use of the proposed approach in determining the sample size of post-epidemic seroepidemiological studies, calculating the 95% confidence interval of observed final size, and conducting relevant hypothesis testing instead of the use of methods that rely on a binomial proportion.
ContributorsNishiura, Hiroshi (Author) / Chowell-Puente, Gerardo (Author) / Castillo-Chavez, Carlos (Author) / Simon M. Levin Mathematical, Computational and Modeling Sciences Center (Contributor) / College of Liberal Arts and Sciences (Contributor) / School of Human Evolution and Social Change (Contributor)
Created2011-03-24
Description
This survey was used to identify the concerns of the public. There are many population techniques that the public feels are harmful to the behavior and nature of the horses. This research defined the different techniques and history of the situation to then analyze the public's opinion of the topic. The survey was trying to determine if any of the techniques could be accepted by the public to control the population of the horses that won’t put the forest, other species, and the herds themselves in danger of possible overpopulation effects.
The data collected from this research showed conflict for the subject. Some of the data was skewed due to conflicting viewpoints on the topic. Analyzing the other aspects of the data we saw noticed that 73% of the servers felt the horses were wild. A majority agreed that the horses should stay there and not be relocated. Some individuals who took the survey were interested in adopting out the horses to help manage horses, there were some concerns with background checks for these adopters since slaughter houses and poor living conditions is a concern.
The data collected from this research showed conflict for the subject. Some of the data was skewed due to conflicting viewpoints on the topic. Analyzing the other aspects of the data we saw noticed that 73% of the servers felt the horses were wild. A majority agreed that the horses should stay there and not be relocated. Some individuals who took the survey were interested in adopting out the horses to help manage horses, there were some concerns with background checks for these adopters since slaughter houses and poor living conditions is a concern.
ContributorsPadayachee, Brittany (Co-author) / Hoover, Sierra (Co-author) / Roen, Duane (Thesis director) / Murphree, Julie (Committee member) / College of Integrative Sciences and Arts (Contributor) / Barrett, The Honors College (Contributor)
Created2020-12
Description
This survey was used to identify the concerns of the public. There are many population techniques that the public feels are harmful to the behavior and nature of the horses. This research defined the different techniques and history of the situation to then analyze the public's opinion of the topic. The survey was trying to determine if any of the techniques could be accepted by the public to control the population of the horses that won’t put the forest, other species, and the herds themselves in danger of possible overpopulation effects.
The data collected from this research showed conflict for the subject. Some of the data was skewed due to conflicting viewpoints on the topic. Analyzing the other aspects of the data we saw noticed that 73% of the servers felt the horses were wild. A majority agreed that the horses should stay there and not be relocated. Some individuals who took the survey were interested in adopting out the horses to help manage horses, there were some concerns with background checks for these adopters since slaughter houses and poor living conditions is a concern.
The data collected from this research showed conflict for the subject. Some of the data was skewed due to conflicting viewpoints on the topic. Analyzing the other aspects of the data we saw noticed that 73% of the servers felt the horses were wild. A majority agreed that the horses should stay there and not be relocated. Some individuals who took the survey were interested in adopting out the horses to help manage horses, there were some concerns with background checks for these adopters since slaughter houses and poor living conditions is a concern.
ContributorsHoover, Sierra Nicole (Co-author) / Padayachee, Brittany (Co-author) / Roen, Duane (Thesis director) / Murphree, Julie (Committee member) / College of Integrative Sciences and Arts (Contributor) / Barrett, The Honors College (Contributor)
Created2020-12
Description
The purpose of this project was to create a workshop for adults without dance experience to immerse them in dance as a form of therapy. The goals of this workshop are to foster physical awareness and physical creativity. There are four main areas the participants would get experience in from this workshop including self-care/awareness, expression, gesture and choreography. These four areas are the ways that the two main goals manifest themselves. For this project I reviewed research by many different professionals from the therapy, psychology, self-care, dance, and dance therapy fields. Their studies as well as my own experience aided in putting together my themes for the workshop and class activities. I include my methodology, lesson plans, a workbook, and my reflection on the process.
ContributorsWilson, Deepika (Author) / Roses-Thema, Cynthia (Thesis director) / Giorgis, Cyndi (Committee member) / College of Integrative Sciences and Arts (Contributor) / Barrett, The Honors College (Contributor)
Created2020-12