Matching Items (7)
Description
Our perspectives and experiences are constantly shaped by the music around us. Through the writing, recording, and producing of color, an eight track concept album, we seek to explore and reflect upon life's most significant milestones. This paper chronicles the year-long creation process of color and highlights the important influences, challenges, and approach which made the album all the more transcendental.
ContributorsHuerta, Salvador (Co-author) / Tom, Nathan (Co-author) / Sandoval, Mathew (Thesis director) / Enriquez, Dante (Committee member) / School of the Arts, Media and Engineering (Contributor) / Department of Information Systems (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
Emerging technologies, such as augmented reality (AR), are growing in popularity and accessibility at a fast pace. Developers are building more and more games and applications with this technology but few have stopped to think about what the best practices are for creating a good user experience (UX). Currently, there are no universally accepted human-computer interaction guidelines for augmented reality because it is still relatively new. This paper examines three features - virtual content scale, indirect selection, and virtual buttons - in an attempt to discover their impact on the user experience in augmented reality. A Battleship game was developed using the Unity game engine with Vuforia, an augmented reality platform, and built as an iOS application to test these features. The hypothesis was that both virtual content scale and indirect selection would result in a more enjoyable and engaging user experience whereas the virtual button would be too confusing for users to fully appreciate the feature. Usability testing was conducted to gauge participants' responses to these features. After playing a base version of the game with no additional features and then a second version with one of the three features, participants rated their experiences and provided feedback in a four-part survey. It was observed during testing that people did not inherently move their devices around the augmented space and needed guidance to navigate the game. Most users were fascinated with the visuals of the game and two of the tested features. It was found that movement around the augmented space and feedback from the virtual content were critical aspects in creating a good user experience in augmented reality.
ContributorsBauman, Kirsten (Co-author) / Benson, Meera (Co-author) / Olson, Loren (Thesis director) / LiKamWa, Robert (Committee member) / School of the Arts, Media and Engineering (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
Machine learning for analytics has exponentially increased in the past few years due to its ability to identify hidden insights in data. It also has a plethora of applications in healthcare ranging from improving image recognition in CT scans to extracting semantic meaning from thousands of medical form PDFs. Currently in the BioElectrical Systems and Technology Lab, there is a biosensor in development that retrieves and analyzes data manually. In a proof of concept, this project uses the neural network architecture to automatically parse and classify a cardiac disease data set as well as explore health related factors impacting cardiac disease in patients of all ages.
ContributorsMurella, Akhila Sainagaki (Author) / Blain-Christen, Jennifer (Thesis director) / Meuth, Ryan (Committee member) / Computer Science and Engineering Program (Contributor) / School of Mathematical and Statistical Sciences (Contributor) / School of the Arts, Media and Engineering (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
The Renewal Philosophy thesis project consisted of two parts: the creation of a website for Dr. Anderson's Renewal Philosophy project and the development of four videos to be used in Dr. Anderson's classes at Arizona State University. The project includes a written description of the processes and methods used in the completion of the website and videos.
ContributorsMarsh, Caleb (Author) / Anderson, Owen (Thesis director) / Fitzsimmons Burton, Kelly (Committee member) / School of the Arts, Media and Engineering (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
Cardiovascular diseases (CVDs) are the leading cause of mortality worldwide, causing nearly 25% of deaths in the United States. Despite the efforts to create in vitro models for the study and treatment of CVDs, these are still limited in their recapitulation of the heart tissue. Thus, the engineering of accurate cardiac models is imperative to gain more understanding and improve the outcome of CVDs. This Ph.D. dissertation focuses on the development and characterization of isogenic cardiac organoids derived from human induced pluripotent stem cells (hiPSCs). Additionally, the integration of chemical and biological cues for enriching their microenvironment and promoting their maturation state and function were studied. First, hiPSC-derived cardiac cells were utilized for the fabrication of multicellular spherical microtissues, namely isogenic cardiac organoids. The cellular composition and culture time of the engineered tissues were optimized to induce cellular aggregation and the formation of cell-cell interactions. Also, ribbon-like gold nanoparticles, namely gold nanoribbons (AuNRs), were synthesized, characterized, and biofunctionalized for their integration into the isogenic cardiac organoids. In-depth biological evaluation of the organoids showed enhanced cardiac maturation markers. Furthermore, a supplement-free cell culture regime was designed and evaluated for fabricating isogenic cardiac organoids. Mechanistic, cellular, and molecular-level studies demonstrated that the presence of hiPSC-derived cardiac fibroblasts (hiPSC-CFs) significantly improves the morphology and gene expression profile of the organoids. Electrophysiological-relevant features of the organoids, such as conduction velocity (CV), were further investigated utilizing a microelectrode array (MEA) platform. It was shown that MEA offers a simple, yet powerful approach to assessing electrophysiological responses of the tissues, where a trend in decreased CV was found due to the presence of hiPSC-CFs. Overall, this dissertation has a broad impact casting light on the development strategy and biological mechanisms that govern the formation and function of isogenic cardiac organoids. Moreover, this study presents two unique approaches to promote maturation of stem cell-derived cardiac organoids: 1) through the integration of novel biofunctionalized nanomaterials, and 2) through a cell culture regime, leading to enhanced function of the organoids. The proposed micro-engineered organoids have broad applications as physiologically relevant tissues for drug discovery, CVDs modeling, and regenerative medicine.
ContributorsPatino, Alejandra (Author) / Nikkhah, Medhi (Thesis advisor) / Blain-Christen, Jennifer (Committee member) / Kodibagkar, Vikram (Committee member) / Vernon, Brent (Committee member) / Zhu, Wuqiang (Committee member) / Arizona State University (Publisher)
Created2023
Description
This dissertation proposes and presents two different passive sigma-delta
modulator zoom Analog to Digital Converter (ADC) architectures. The first ADC is fullydifferential, synthesizable zoom-ADC architecture with a passive loop filter for lowfrequency Built in Self-Test (BIST) applications. The detailed ADC architecture and a step
by step process designing the zoom-ADC along with a synthesis tool that can target various
design specifications are presented. The design flow does not rely on extensive knowledge
of an experienced ADC designer. Two example set of BIST ADCs have been synthesized
with different performance requirements in 65nm CMOS process. The first ADC achieves
90.4dB Signal to Noise Ratio (SNR) in 512µs measurement time and consumes 17µW
power. Another example achieves 78.2dB SNR in 31.25µs measurement time and
consumes 63µW power. The second ADC architecture is a multi-mode, dynamically
zooming passive sigma-delta modulator. The architecture is based on a 5b interpolating
flash ADC as the zooming unit, and a passive discrete time sigma delta modulator as the
fine conversion unit. The proposed ADC provides an Oversampling Ratio (OSR)-
independent, dynamic zooming technique, employing an interpolating zooming front-end.
The modulator covers between 0.1 MHz and 10 MHz signal bandwidth which makes it
suitable for cellular applications including 4G radio systems. By reconfiguring the OSR,
bias current, and component parameters, optimal power consumption can be achieved for
every mode. The ADC is implemented in 0.13 µm CMOS technology and it achieves an
SNDR of 82.2/77.1/74.2/68 dB for 0.1/1.92/5/10MHz bandwidth with 1.3/5.7/9.6/11.9mW
power consumption from a 1.2 V supply.
modulator zoom Analog to Digital Converter (ADC) architectures. The first ADC is fullydifferential, synthesizable zoom-ADC architecture with a passive loop filter for lowfrequency Built in Self-Test (BIST) applications. The detailed ADC architecture and a step
by step process designing the zoom-ADC along with a synthesis tool that can target various
design specifications are presented. The design flow does not rely on extensive knowledge
of an experienced ADC designer. Two example set of BIST ADCs have been synthesized
with different performance requirements in 65nm CMOS process. The first ADC achieves
90.4dB Signal to Noise Ratio (SNR) in 512µs measurement time and consumes 17µW
power. Another example achieves 78.2dB SNR in 31.25µs measurement time and
consumes 63µW power. The second ADC architecture is a multi-mode, dynamically
zooming passive sigma-delta modulator. The architecture is based on a 5b interpolating
flash ADC as the zooming unit, and a passive discrete time sigma delta modulator as the
fine conversion unit. The proposed ADC provides an Oversampling Ratio (OSR)-
independent, dynamic zooming technique, employing an interpolating zooming front-end.
The modulator covers between 0.1 MHz and 10 MHz signal bandwidth which makes it
suitable for cellular applications including 4G radio systems. By reconfiguring the OSR,
bias current, and component parameters, optimal power consumption can be achieved for
every mode. The ADC is implemented in 0.13 µm CMOS technology and it achieves an
SNDR of 82.2/77.1/74.2/68 dB for 0.1/1.92/5/10MHz bandwidth with 1.3/5.7/9.6/11.9mW
power consumption from a 1.2 V supply.
ContributorsEROL, OSMAN EMIR (Author) / Ozev, Sule (Thesis advisor) / Kitchen, Jennifer (Committee member) / Ogras, Umit Y. (Committee member) / Blain-Christen, Jennifer (Committee member) / Arizona State University (Publisher)
Created2018
Description
In many real-world machine learning classification applications, well labeled training data can be difficult, expensive, or even impossible to obtain. In such situations, it is sometimes possible to label a small subset of data as belonging to the class of interest though it is impractical to manually label all data not of interest. The result is a small set of positive labeled data and a large set of unknown and unlabeled data. This is known as the Positive and Unlabeled learning (PU learning) problem, a type of semi-supervised learning. In this dissertation, the PU learning problem is rigorously defined, several common assumptions described, and a literature review of the field provided. A new family of effective PU learning algorithms, the MLR (Modified Logistic Regression) family of algorithms, is described. Theoretical and experimental justification for these algorithms is provided demonstrating their success and flexibility. Extensive experimentation and empirical evidence are provided comparing several new and existing PU learning evaluation estimation metrics in a wide variety of scenarios. The surprisingly clear advantage of a simple recall estimate as the best estimate for overall PU classifier performance is described. Finally, an application of PU learning to the field of solar fault detection, an area not previously explored in the field, demonstrates the advantage and potential of PU learning in new application domains.
ContributorsJaskie, Kristen P (Author) / Spanias, Andreas (Thesis advisor) / Blain-Christen, Jennifer (Committee member) / Tepedelenlioğlu, Cihan (Committee member) / Thiagarajan, Jayaraman (Committee member) / Arizona State University (Publisher)
Created2021