Matching Items (575)
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Diseases have been part of human life for generations and evolve within the population, sometimes dying out while other times becoming endemic or the cause of recurrent outbreaks. The long term influence of a disease stems from different dynamics within or between pathogen-host, that have been analyzed and studied by

Diseases have been part of human life for generations and evolve within the population, sometimes dying out while other times becoming endemic or the cause of recurrent outbreaks. The long term influence of a disease stems from different dynamics within or between pathogen-host, that have been analyzed and studied by many researchers using mathematical models. Co-infection with different pathogens is common, yet little is known about how infection with one pathogen affects the host's immunological response to another. Moreover, no work has been found in the literature that considers the variability of the host immune health or that examines a disease at the population level and its corresponding interconnectedness with the host immune system. Knowing that the spread of the disease in the population starts at the individual level, this thesis explores how variability in immune system response within an endemic environment affects an individual's vulnerability, and how prone it is to co-infections. Immunology-based models of Malaria and Tuberculosis (TB) are constructed by extending and modifying existing mathematical models in the literature. The two are then combined to give a single nine-variable model of co-infection with Malaria and TB. Because these models are difficult to gain any insight analytically due to the large number of parameters, a phenomenological model of co-infection is proposed with subsystems corresponding to the individual immunology-based model of a single infection. Within this phenomenological model, the variability of the host immune health is also incorporated through three different pathogen response curves using nonlinear bounded Michaelis-Menten functions that describe the level or state of immune system (healthy, moderate and severely compromised). The immunology-based models of Malaria and TB give numerical results that agree with the biological observations. The Malaria--TB co-infection model gives reasonable results and these suggest that the order in which the two diseases are introduced have an impact on the behavior of both. The subsystems of the phenomenological models that correspond to a single infection (either of Malaria or TB) mimic much of the observed behavior of the immunology-based counterpart and can demonstrate different behavior depending on the chosen pathogen response curve. In addition, varying some of the parameters and initial conditions in the phenomenological model yields a range of topologically different mathematical behaviors, which suggests that this behavior may be able to be observed in the immunology-based models as well. The phenomenological models clearly replicate the qualitative behavior of primary and secondary infection as well as co-infection. The mathematical solutions of the models correspond to the fundamental states described by immunologists: virgin state, immune state and tolerance state. The phenomenological model of co-infection also demonstrates a range of parameter values and initial conditions in which the introduction of a second disease causes both diseases to grow without bound even though those same parameters and initial conditions did not yield unbounded growth in the corresponding subsystems. This results applies to all three states of the host immune system. In terms of the immunology-based system, this would suggest the following: there may be parameter values and initial conditions in which a person can clear Malaria or TB (separately) from their system but in which the presence of both can result in the person dying of one of the diseases. Finally, this thesis studies links between epidemiology (population level) and immunology in an effort to assess the impact of pathogen's spread within the population on the immune response of individuals. Models of Malaria and TB are proposed that incorporate the immune system of the host into a mathematical model of an epidemic at the population level.
ContributorsSoho, Edmé L (Author) / Wirkus, Stephen (Thesis advisor) / Castillo-Chavez, Carlos (Thesis advisor) / Chowell-Puente, Gerardo (Committee member) / Arizona State University (Publisher)
Created2011
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In the past decade, a significant shift has emerged around immigration policy, as advocates and policymakers have made various efforts to pass state and local policies related to immigrant integration or restrictions. This thesis offers original insights into current dynamics in immigration federalism through interviews with lawmakers and community activists

In the past decade, a significant shift has emerged around immigration policy, as advocates and policymakers have made various efforts to pass state and local policies related to immigrant integration or restrictions. This thesis offers original insights into current dynamics in immigration federalism through interviews with lawmakers and community activists in Arizona, a leading state when it comes to restricting the lives of undocumented immigrants. Advancing a new framework that connects the lived experience of officials and activists to partisanship, policy, key events, demographics, and racializing events, this thesis bridges isolated bodies of scholarship on immigration and seeks to demonstrate how every person (not just immigrant) are part of America’s current challenges to become a more inclusive nation of immigrants.

ContributorsNeville, Christopher Francis (Author) / Colbern, Allan (Thesis director) / Martinez-Orosco, Rafael (Committee member) / School of Social and Behavioral Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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Something Like Human explores corporate social responsibility through a triple lens, providing a content analysis using previous literature and history as the standards for evaluation. Section I reviews the history of corporate social responsibility and how it is currently understood and employed today. Section II turns its focus to a

Something Like Human explores corporate social responsibility through a triple lens, providing a content analysis using previous literature and history as the standards for evaluation. Section I reviews the history of corporate social responsibility and how it is currently understood and employed today. Section II turns its focus to a specific socially conscious corporation, Lush Cosmetics, examining its practices considering the concepts provided in Section I and performing a close analysis of its promotional materials. Section III consists of a mock marketing campaign designed for Lush in light of their social commitments. By the end of this thesis, the goal for the reader is to ask: Can major corporations be something like human?

ContributorsDalgleish, Alayna Rose (Author) / Gruber, Diane (Thesis director) / Thornton, Leslie-Jean (Committee member) / School of Social and Behavioral Sciences (Contributor, Contributor) / Walter Cronkite School of Journalism and Mass Comm (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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Veterans are approximately 30% more likely than non-veterans to suffer from severe hearing impairment. Tinnitus, or ringing in the ears, which is increasingly common among military service men and women, has been linked to significant cognitive and psychological impairment and can be worsened by the same sounds that trigger post-traumatic

Veterans are approximately 30% more likely than non-veterans to suffer from severe hearing impairment. Tinnitus, or ringing in the ears, which is increasingly common among military service men and women, has been linked to significant cognitive and psychological impairment and can be worsened by the same sounds that trigger post-traumatic stress disorder (PTSD). In fact, tinnitus and PTSD often present as comorbidities, and recent studies suggest these two disorders may share a common neurological pathway. Additional studies are required to better understand the connection between hearing loss and impaired cognitive function such as that observed in with PTSD. Here, we use the fruit fly, Drosophila melanogaster, to explore the relationship between hearing loss and cognitive function. Negative geotaxis climbing assays and courtship behavior analysis were used to examine neurobehavioral changes induced by prolonged, intense auditory stimulation. Preliminary results suggest that exposure to loud noise for an extended period of time significantly affected Drosophila behavior, with males being more sensitive than females. Based on our results, there appears to be a potential connection between noise exposure and behavior, further suggesting that Drosophila could be an effective model to study the link between hearing loss and PTSD.

ContributorsMichael, Allison Faye (Author) / Hackney-Price, Jennifer (Thesis director) / Sellner, Erin (Committee member) / School of Social and Behavioral Sciences (Contributor) / School of Mathematical and Natural Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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Socioeconomic differences have driven society and laid the foundation for the types of opportunities and resources one is eligible to receive. Higher socioeconomic status provides individuals the chance of obtaining an overall better education, occupation, and income. We see this with particular clarity when we examine healthcare. The World Health

Socioeconomic differences have driven society and laid the foundation for the types of opportunities and resources one is eligible to receive. Higher socioeconomic status provides individuals the chance of obtaining an overall better education, occupation, and income. We see this with particular clarity when we examine healthcare. The World Health Organization has regarded healthcare as a fundamental human right, except socioeconomically disadvantaged individuals not only do not have equal access to healthcare, but they also often receive a lower quality of care. These socioeconomic differences are often paired with racial differences, resulting in one group, or set of groups, having social advantage over the others. Although this problem has been discussed throughout the past century, it has not been properly addressed materially and practically. Unequal access to quality healthcare is especially highlighted throughout the COVID-19 pandemic, where there has been evidence that minorities, in particular Black communities, have received inadequate care. Quality healthcare has become unaffordable and a luxury that only certain groups get the privilege of receiving. Not only that, but the ongoing inequalities in the healthcare system have gone so far that they have instilled hostility and mistrust towards the healthcare system.

ContributorsMartinez Castro, Karen (Author) / Sturgess, Jessica (Thesis director) / Sellner, Erin (Committee member) / School of Social and Behavioral Sciences (Contributor) / School of Mathematical and Natural Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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In 2020, the world was swept by a global pandemic. It disrupted the lives of millions; many lost their jobs, students were forced to leave schools, and children were left with little to do while quarantined at their houses. Although the media outlets covered very little of how children were

In 2020, the world was swept by a global pandemic. It disrupted the lives of millions; many lost their jobs, students were forced to leave schools, and children were left with little to do while quarantined at their houses. Although the media outlets covered very little of how children were being affected by COVID-19, it was obvious that their group was not immune to the issues the world was facing. Being stuck at home with little to do took a mental and physical toll on many kids. That is when EVOLVE Academy became an idea; our team wanted to create a fully online platform for children to help them practice and evolve their athletics skills, or simply spend part of their day performing a physical and health activity. Our team designed a solution that would benefit children, as well as parents that were struggling to find engaging activities for their kids while out of school. We quickly encountered issues that made it difficult for us to reach our target audience and make them believe and trust our platform. However, we persisted and tried to solve and answer the questions and problems that came along the way. Sadly, the same pandemic that opened the widow for EVOLVE Academy to exist, is now the reason people are walking away from it. Children want real interaction. They want to connect with other kids through more than just a screen. Although the priority of parents remains the safety and security of their kids, parents are also searching and opting for more “human” interactions, leaving EVOLVE Academy with little room to grow and succeed.

ContributorsHernandez, Melany (Co-author) / Parmenter, Taylor (Co-author) / Byrne, Jared (Thesis director) / Kunowski, Jeffrey (Committee member) / Lee, Christopher (Committee member) / Thunderbird School of Global Management (Contributor, Contributor) / School of Social and Behavioral Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
Description

Evidence of a widening political divide between the Democrat and Republican parties creates concern over the possible ramifications of this phenomenon. One method of assessing dissonance between political parties is through a medium that is shaped by personal beliefs: online dating. Previous research finds that political choice homophily, or a

Evidence of a widening political divide between the Democrat and Republican parties creates concern over the possible ramifications of this phenomenon. One method of assessing dissonance between political parties is through a medium that is shaped by personal beliefs: online dating. Previous research finds that political choice homophily, or a preference for those who are politically similar, is relevant in online dating settings. Researchers find that individuals are significantly more likely to be attracted to or pursue others who have similar political views to themselves. There is, however, a gap in knowledge regarding online dating that occurs separately from conventional online dating sites. Mobile dating apps, applications that are highly popular amongst young adults, have not been thoroughly explored with political choice homophily in mind. The current study aims to test the correlation between dating preference and political beliefs, using the mobile dating app Bumble as a template for a mock (fake) dating app scenario. In the dating app survey that was distributed to 132 ASU students, participants completed a simulated “matching” section where they matched with a list of 15 fabricated Bumble profiles. The fake Bumble profiles randomly contained politically charged or politically neutral statements in the basic info section. Political affiliation of the participant was measured using a sliding scale that quantifies the unidimensional conservative-liberal spectrum on a 0-100 numerical scale. Findings of the survey show that there was no significant difference between participant preference towards politically charged vs. politically neutral mock profiles.

ContributorsGilmore, Ethan James (Author) / Lewis, Stephen (Thesis director) / Halavais, Alexander (Committee member) / School of Social and Behavioral Sciences (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
Description

This thesis will assess the relationship between race and perceptions of incarceration through responses gathered from interviews administered to men incarcerated at the Arizona State Prison Complex in Florence, Arizona. The interviews were conducted by incarcerated men through a Participatory Action Research (PAR) project to enhance the prison environment. Critically,

This thesis will assess the relationship between race and perceptions of incarceration through responses gathered from interviews administered to men incarcerated at the Arizona State Prison Complex in Florence, Arizona. The interviews were conducted by incarcerated men through a Participatory Action Research (PAR) project to enhance the prison environment. Critically, men who were interviewed answered the question “What would you do if you were the Director of the Department of Corrections?” The purpose of this thesis is twofold. First, what are the major themes provided to this question? Second, did these themes differ depending on the race or ethnicity of the respondent? The results from this survey can provide a more informed future for corrections that acknowledges the unique criminal justice system experiences held by members of different racial and ethnic groups.

ContributorsQuintero, Karen Rotna (Author) / Wright, Kevin (Thesis director) / Young, Jacob (Committee member) / School of Social and Behavioral Sciences (Contributor) / School of International Letters and Cultures (Contributor) / College of Health Solutions (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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Solution methods for certain linear and nonlinear evolution equations are presented in this dissertation. Emphasis is placed mainly on the analytical treatment of nonautonomous differential equations, which are challenging to solve despite the existent numerical and symbolic computational software programs available. Ideas from the transformation theory are adopted allowing one

Solution methods for certain linear and nonlinear evolution equations are presented in this dissertation. Emphasis is placed mainly on the analytical treatment of nonautonomous differential equations, which are challenging to solve despite the existent numerical and symbolic computational software programs available. Ideas from the transformation theory are adopted allowing one to solve the problems under consideration from a non-traditional perspective. First, the Cauchy initial value problem is considered for a class of nonautonomous and inhomogeneous linear diffusion-type equation on the entire real line. Explicit transformations are used to reduce the equations under study to their corresponding standard forms emphasizing on natural relations with certain Riccati(and/or Ermakov)-type systems. These relations give solvability results for the Cauchy problem of the parabolic equation considered. The superposition principle allows to solve formally this problem from an unconventional point of view. An eigenfunction expansion approach is also considered for this general evolution equation. Examples considered to corroborate the efficacy of the proposed solution methods include the Fokker-Planck equation, the Black-Scholes model and the one-factor Gaussian Hull-White model. The results obtained in the first part are used to solve the Cauchy initial value problem for certain inhomogeneous Burgers-type equation. The connection between linear (the Diffusion-type) and nonlinear (Burgers-type) parabolic equations is stress in order to establish a strong commutative relation. Traveling wave solutions of a nonautonomous Burgers equation are also investigated. Finally, it is constructed explicitly the minimum-uncertainty squeezed states for quantum harmonic oscillators. They are derived by the action of corresponding maximal kinematical invariance group on the standard ground state solution. It is shown that the product of the variances attains the required minimum value only at the instances that one variance is a minimum and the other is a maximum, when the squeezing of one of the variances occurs. Such explicit construction is possible due to the relation between the diffusion-type equation studied in the first part and the time-dependent Schrodinger equation. A modication of the radiation field operators for squeezed photons in a perfect cavity is also suggested with the help of a nonstandard solution of Heisenberg's equation of motion.
ContributorsVega-Guzmán, José Manuel, 1982- (Author) / Sulov, Sergei K (Thesis advisor) / Castillo-Chavez, Carlos (Thesis advisor) / Platte, Rodrigo (Committee member) / Chowell-Puente, Gerardo (Committee member) / Arizona State University (Publisher)
Created2013
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Communication skills are vital for the world we inhabit. Both oral and written communication are some of the most sought-after skills in the job market today; this holds true in science, technology, engineering and mathematics (STEM) fields. Despite the high demand for communication skills, communication classes are not required for

Communication skills are vital for the world we inhabit. Both oral and written communication are some of the most sought-after skills in the job market today; this holds true in science, technology, engineering and mathematics (STEM) fields. Despite the high demand for communication skills, communication classes are not required for some STEM majors (Missingham, 2006). STEM major maps are often so packed with core classes that they nearly exclude the possibility of taking communication courses. Students and job seekers are told they need to be able to communicate to succeed but are not given any information or support in developing their skills. Scientific inquiry and discovery cannot be limited to only those that understand high-level jargon and have a Ph.D. in a subject. STEM majors and graduates must be able to translate information to communities beyond other experts. If they cannot communicate the impact of their research and discoveries, who is going to listen to them?<br/>Overall, the literature around communication in STEM fields demonstrate the need for and value of specific, teachable communication skills. This paper will examine the impact of a communication training module that teaches specific communication skills to BIO 182: General Biology II students. The communication training module is an online module that teaches students the basics of oral communication. The impact of the module will be examined through the observation of students’ presentations.

ContributorsLivingston, Elisabeth Shaw (Author) / Wentzel, Bonnie (Thesis director) / Sellner, Erin (Committee member) / School of Social and Behavioral Sciences (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2021-05