The microbiome and the immune system are known to work in conjunction to modulate the clearance of pathogens and tolerance of beneficial microbes. A growing area of research seeks to study the potential extent of the involvement of the microbiome in modulating and supporting the immune system during acute allograft rejection. It has been hypothesized that the localized microbiota in each organ produce metabolites that instigate inflammatory immune responses, but whether microbiota interactions precipitate acute allograft rejection is unknown. Therefore, this study focuses on microbiome shifts in the gut and kidney after inducing acute renal transplant rejection in order to implicate gut dysbiosis as a precursor or supporter of allograft rejection. This study also subsequently explores the use of an immune-modulating protein in order to determine differences in the outcome of transplant rejection and potential differences in intestinal microbial load. This experiment sought to induce rejection in BALB/c mice through the use of C57BL/6 mouse renal slivers. Microbiome abundance was analyzed in all experimental groups. Understanding the role of the microbiome in transplant rejection has vast clinical implications and has the potential to enhance pre- and post-operative treatment, and immune management and quality of life following organ transplant.

Since the inception of what is now known as the Behavioral Analysis Unit (BAU) at the Federal Bureau of Investigation (FBI) in the 1970s, criminal profiling has become an increasingly prevalent entity in both forensic science and the popular imagination. The fundamental idea of which profiling is premised – behavior as a reflection of personality – has been the subject of a great deal of misunderstanding, with professionals and nonprofessionals alike questioning whether profiling represents an art or a science and what its function in forensic science should be. To provide a more thorough understanding of criminal profiling’s capabilities and its efficacy as a law enforcement tool, this thesis will examine the application of criminal profiling to investigations, various court rulings concerning profiling’s admissibility, and the role that popular media plays in the perception and function of the practice. It will also discuss how future research and regulatory advancements may strengthen criminal profiling’s scientific merit and legitimacy.

This thesis looks at three different inventory management strategies that can be implemented into a small business. Using GameSet Style as a research subject, this study analyzes current practices and problems that can be fixed when dealing with an excess amount of inventory. The three inventory management strategies that are compared are demand forecasting, inventory management software, and ABC analysis. Inventory can be a small business's highest cost if not managed effectively. The goal for this thesis is to find the best obtainable solution for a small business like GameSet that can be implemented into their business strategy.

Music has consistently been documented as a manner to bring people together across cultures throughout the world. In this research, we propose that people use similar musical tastes as a strong sign of potential social connection. To investigate this notion, we draw on literature examining how music merges the public/private self, the link to personality, and group identity, as well as how it is linked to romantic relationships. Thus, music can be a tool when wanting to get to know someone else and/or forge a platonic relationship. To test this hypothesis, we designed an experiment comparing music relative to another commonality (sharing a sports team in common) to see which factor is stronger in triggering an online social connection. We argue that people believe they have more in common with someone who shares similar music taste compared to other commonalities. We discuss implications for marketers on music streaming platforms.

Claiming Impossible Bodies is a collection of poetry and collage exploring gender and sexuality through the lens of the vampire. For this project, I researched various representations of the vampires through folklore, classical and modern literature, film, and pop culture. The liminality of the vampire allows such figures to take different forms and identities, ranging from dark and grotesque creatures, such as the succubus or incubus from mythology, to modern sex-icons, like Edward Cullen from the Twilight Saga. Considering this wide range of performances by vampiric figures throughout history, the poems in this manuscript seek to deconstruct the binaries that vampires live between and expose the liminality in social norms that attempt to define our identities and shape our performances.

The novel Coronavirus Disease 2019 exposed issues in the supply chain for N95 face masks. The demand for protective face masks spiked globally and domestically due to the unexpected outbreak of the pandemic. An important issue was the dependency on N95 mask production in countries abroad. The focus on face masks in this thesis accounts for all models of the N95 mask.<br/>This thesis will focus on onshore and offshore production of N95 face masks before and during the pandemic. Specifically, we will focus on (1) the production of masks in 2019; (2) 3M, Honeywell, and Prestige Ameritech’s production changes; (3) the observations made by All The Things LLC, a broker for face masks; (4) the rise of counterfeit masks and actions taken to stop counterfeit production; (4) actions taken by the federal government to aid in production and distribution; and (5) future research opportunities on this topic. This research project into the production of N95 face masks ceased in February of 2021. <br/>This thesis defends the critical need for more domestically produced N95 masks. The U.S. needs to increase the number of N95 masks produced domestically, manage the Strategic National Stockpile to eliminate masks past their shelf life, and create a plan to replenish the stockpile to reduce the possibility of a shortage when the next public health emergency takes place.

As climate change continues to escalate natural hazards around the globe, certain communities feel the impacts of these disasters more so than others. After Hurricane Maria devastated communities in 2017, Puerto Rico struggled to respond to the needs of its citizens, particularly those in rural areas. Many of the regions affected did not have resilient community structures in place to be able to withstand the systemic ripple effects of the hurricane. However, various community endeavors have developed post-Hurricane Maria to foster community collaboration and resiliency, including the development of agricultural tourism, otherwise known as agritourism. <br/>Although agritourism has begun to develop in rural regions of Puerto Rico, including the municipalities of Utuado, Ciales, Florida, and Jayuya, a systems-understanding is lacking of the current agritourism situation in the region and its related capacities, limitations, and opportunities of agritourism. To address this gap, a spatially explicit understanding and map of the underlying tourism infrastructure is needed to support the development of sustainable agritourism in Utuado, Jayuya, Ciales, and Florida municipalities in Puerto Rico. <br/>This report spatially represents the current state of tourism opportunities in the region as a result of asking “What are the spatial networks of gastronomy, accommodations, farms, and attractions that support the development of agritourism in Utuado, Jayuya, Ciales and Florida municipalities in Puerto Rico?” Three steps lead to the spatial representation starting with developing a comprehensive inventory. Second, we visualize the spatial map through Google Maps. Lastly, we explore the larger context of the report through an ArcGIS Storymap. The inventory will help with better understanding the number and variety of tourism resources available. The spatial visualization will help with understanding the distribution of resources and explore potential connections between resources and what relationships could be fostered in the future. Lastly, the ArcGIS Storymap will serve as a framework for outlining the future development of the SARE project. Overall, this report outlines the spatial maps of tourism resources and provides a tool to be used by community partners, tourists, and project partners.

Consider Steven Cryos’ words, “When disaster strikes, the time to prepare has passed.” Witnessing domestic water insecurity in events such as Hurricane Katrina, the instability in Flint, Michigan, and most recently the winter storms affecting millions across Texas, we decided to take action. The period between a water supply’s disruption and restoration is filled with anxiety, uncertainty, and distress -- particularly since there is no clear indication of when, exactly, restoration comes. It is for this reason that Water Works now exists. As a team of students from diverse backgrounds, what started as an honors project with the Founders Lab at Arizona State University became the seed that will continue to mature into an economically sustainable business model supporting the optimistic visions and tenants of humanitarianism. By having conversations with community members, conducting market research, competing for funding and fostering progress amid the COVID-19 pandemic, our team’s problem-solving traverses the disciplines. The purpose of this paper is to educate our readers about a unique solution to emerging issues of water insecurity that are nested across and within systems who could benefit from the introduction of a personal water reclamation system, showcase our team’s entrepreneurial journey, and propose future directions that will this once pedagogical exercise to continue fulfilling its mission: To heal, to hydrate, and to help bring safe water to everyone.

In this paper, our Founders Lab team members — Jacob Benevento, Sydney Evans, and Alec Whiteley — recount the year-long entrepreneurial journey that led to the creation and launch of our venture, Certified Circular. Certified Circular is a program that certifies on-campus events for implementing circular practices into their activities as well as off-campus businesses. The venture was formed in response to our group’s propelling question and industry selection, which called on us to create and market a venture within the ethical circular economy.