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- Creators: Beethoven, Ludwig van, 1770-1827
- Status: Published
Description
Glioblastomas (GBMs) are the most aggressive type of brain tumor. GBMs are known for their aggressive and invasive nature because of their ability to easily grow and spread into the surrounding areas of the brain. The annual incidence rate of GBM is 2 to 3 people per 100,000 people in the United States and Europe, and the median survival for patients with an aggressive GBM is 14.6 months. The standard of care for GBMs follows a protocol of surgery, radiation concurrent with the chemotherapeutic drug, temozolomide (TMZ), followed by the administration of up to 6 cycles of TMZ in an adjuvant setting. The objective of this retrospective study was to compare the clinical responses in a patient cohort from varying amount of adjuvant TMZ cycles. Using patient overall survival, the responses to TMZ cycles were tested within different groupings, and the patient covariates were analyzed. The results from the different analyses indicated that survival success of GBM patients is not solely dependent on the number of TMZ cycles, but that other covariates can also affect survival outcomes.
ContributorsSuri, Yash (Author) / Swanson, Kristin (Thesis director) / Massey, Susan (Committee member) / School of Geographical Sciences and Urban Planning (Contributor) / School for the Science of Health Care Delivery (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
Hispanic children have the highest prevalence of obesity versus other ethnic groups. This leaves this population susceptible to many adverse health risks, including hypertension, cardiovascular disease, and high blood pressure. Unfortunately, little research has been done investigating the contributing cause to this issue, specifically common sedentary behaviors in children that limit physical activity and it’s purpose in expending energy. Amongst these behaviors, amount of time spent on electronic devices has proven to have increased drastically in recent years. The relationship between screen time and electronic device use, specifically with television, video games, and computer usage, and physical activity levels, and how those affect cardiometabolic disease risk factors, were explored in this study. Participants of this study were elementary school-aged children from Maricopa County, AZ. Electronic device usage, physical activity amounts, and presence of the specific devices in the child’s were collected from the participants’ parents through self-reported survey questions. Anthropometric and biochemical markers of cardiometabolic disease risk were directly measured. The average time spent engaged in physical activity per day by these participants was 20.02 ± 21.1 minutes and the average total screen time per day was 655 ± 605 minutes. Findings showed strong significance between total screen time and computer and video game use (r=0.482; p=0.01 and r=0.784; p=0.01, respectively). Video game time in the group of children with a video game in their room (350.66 ± 445.96 min/day) was significantly higher than the sample of kids without one in their room (107.19 ± 210.0 min/day ; p=0.000). Total screen time was also significantly greater with children who had a video game system in their room (927.56 ± 928.7 min/day) versus children who did not (543.14 ± 355.11 min/day; p=0.006). Additionally, significance was found showing children with a computer in the bedroom spent more time using the computer per day (450.95 ± 377.95 min/day), compared to those children who did not have a computer in their room (333.5 ± 395.6 min/day; p=0.048). No significant association was found between metabolic markers and screen time. However, HDL-cholesterol, triglycerides, and insulin proved to be dependent on BMI percentile (r=-0.582; p=0.01, r=0.476; p=0.01, r=0.704; p=0.01 respectively). Our data suggest further research needs to be done investigating other potential sources that limit physical activity so that strategies can focus on reducing obesity incidence and the associated health risks. Future studies should use larger sample sizes to be more representative of this population, and develop more direct observations instead of self-reported values to limit bias.
ContributorsGaines, Michael Anthony (Author) / Vega-Lopez, Sonia (Thesis director) / Crespo, Noe (Committee member) / School for the Science of Health Care Delivery (Contributor) / School of Nutrition and Health Promotion (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
Health and wellness coaching has shown promising results in numerous studies. However, there is lack of published research evaluating the impact of using wellness-coaching interventions implemented by coaching trainees in a worksite setting. The main objective was to examine the changes in self-reported scores of the 12-wellness dimensions of health in ASU students, faculty, and staff after participating in an eight-week health and wellness program. The secondary outcome was to evaluate if additional health and wellness recommendations had a significant impact. The participants were aged 18 to 58 years and were divided into two groups: the first group received health and wellness coaching, while the second group received the health and wellness coaching in addition to recommendations on specific worksite social/embedded programs and supporting activities. Both groups had significantly increased scores in Eating/Nutrition and Thinking (p<0.001 and P<0.014 respectively). Health and wellness coaching trainees were effective in assisting clients on reaching realistic progress. Our program shows potential benefits in worksite wellness.
ContributorsBlackwell, Jared (Author) / Gregory-Mercado, Karen (Thesis director) / Collins, Michael (Committee member) / Scribner, Christina (Committee member) / School of Nutrition and Health Promotion (Contributor) / School for the Science of Health Care Delivery (Contributor) / Barrett, The Honors College (Contributor)
Created2017-12
Description
Grief reaches across all human differences and boundaries. Grief, when it does not resolve on its own, is known as complicated grief. Parents of children who die are at increased risk for experiencing complicated grief. This case study seeks commonalities and possible contributing factors for the creation of a non-profit in reaction to the death of a child. This study finds that previous achievements such as completing a marathon or graduating from a graduate program may indicate the presence of characteristics like resilience that result in the creation of a non-profit.
ContributorsGood, Jennifer Rose (Author) / Bozeman, Barry (Thesis director) / Gaughan, Monica (Committee member) / School of Human Evolution and Social Change (Contributor) / Economics Program in CLAS (Contributor) / School for the Science of Health Care Delivery (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
Description
Introduction: Health disparities for the Native American population in the United States have been well documented for years. Native Americans face many barriers to healthcare access, including low socioeconomic status, historical trauma, and lack of access to healthcare facilities. Barriers to healthcare and challenges associated with achieving optimal health among Native Americans contribute to health disparities within these populations. If these barriers are to be overcome, they must be understood and addressed. Purpose: The purpose of this review was to identify barriers to healthcare access for Native American populations as well as strategies to address barriers. Method: A preliminary scan of several online databases was conducted. Key terms used in the search included American Indians, Native American, healthcare, healthcare access, health disparities, barriers, and intervention. Articles were selected based on relevance, and data from each chosen article were extracted and categorized. Results: The initial search resulted in 272 articles of potential interest. Based on the abstract review, 32 were deemed relevant, and full text reviews were completed. Based on the full text review, an additional 10 articles were excluded, resulting in a final review of 22 articles. The articles addressed barriers related to various health conditions: cancer treatment, drug or alcohol use, maternal and child health, historical trauma, diabetes and chronic illnesses, and oral health. Conclusion: Native Americans face several barriers to healthcare access that are associated with social, physical, and mental health disparities. Successful efforts to address these barriers include patient-centered, culturally-competent interventions. Others include interventions which focus on community involvement.
ContributorsMohamed, Hebah (Co-author) / Mohamed, Hitham (Co-author) / Coplan, Bettie (Thesis director) / Reddy, Swapna (Committee member) / School for the Science of Health Care Delivery (Contributor) / Barrett, The Honors College (Contributor)
Created2017-12
Description
In the United States, the Latino population is projected to reach approximately 28.6% of the total U.S. population by 2060. Despite their growing presence, Latinos encounter health disparities and worse health outcomes in comparison to their non-Hispanic White (NHW) counterparts. Latinos/ Hispanics have a higher prevalence of diabetes, hypertension, obesity, and late stage cancer diagnosis. Various social determinants of health (SDoH) such as socioeconomic status, education, insurance enrollment, language proficiency, immigration status among other variables intersect to influence Latino health status. However, even when all those factors were held equal, disparities remained. The aforementioned list did not include race/ethnicity, though race/ethnicity is a critical SDoH that influences one's access to care and the quality of care they receive. As such, examining the role of race may be the key to reducing persistent health disparities in access to care, quality of care, and health outcomes.
ContributorsChen, Diana (Author) / Reddy, Swapna (Thesis director) / Cuya Gavilano, Lorena (Committee member) / School for the Science of Health Care Delivery (Contributor) / College of Integrative Sciences and Arts (Contributor) / Barrett, The Honors College (Contributor)
Created2017-12
ContributorsBeethoven, Ludwig van, 1770-1827 (Composer)
ContributorsBeethoven, Ludwig van, 1770-1827 (Composer)
ContributorsBeethoven, Ludwig van, 1770-1827 (Composer)