Matching Items (99)
![130233-Thumbnail Image.png](https://d1rbsgppyrdqq4.cloudfront.net/s3fs-public/styles/width_400/public/2021-04/130233-Thumbnail%20Image.png?versionId=tRy9B9uEY.mQ1iztew7lSq8GGfjskxU2&X-Amz-Content-Sha256=UNSIGNED-PAYLOAD&X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Credential=AKIASBVQ3ZQ42ZLA5CUJ/20240615/us-west-2/s3/aws4_request&X-Amz-Date=20240615T052925Z&X-Amz-SignedHeaders=host&X-Amz-Expires=120&X-Amz-Signature=3e12ec4299b7c1f60e6b94ba22ad910e1ee7d2354f89e1e8b89aea3e35e051ec&itok=e8zEJG9s)
ContributorsBlume, G (Author) / Hild, Konstanze (Author) / Marko, I. P. (Author) / Hosea, T. J. C. (Author) / Yu, S.-Q. (Author) / Chaparro, S. A. (Author) / Samal, N. (Author) / Johnson, Shane R. (Author) / Zhang, Yong-Hang (Author) / Sweeney, S. J. (Author)
Created2012
![130234-Thumbnail Image.png](https://d1rbsgppyrdqq4.cloudfront.net/s3fs-public/styles/width_400/public/2021-04/130234-Thumbnail%20Image.png?versionId=nG04fSkw92JGkCFI_bvHI4cnBHNl5rJv&X-Amz-Content-Sha256=UNSIGNED-PAYLOAD&X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Credential=AKIASBVQ3ZQ42ZLA5CUJ/20240615/us-west-2/s3/aws4_request&X-Amz-Date=20240615T201348Z&X-Amz-SignedHeaders=host&X-Amz-Expires=120&X-Amz-Signature=ce4fe5de26fa1a32f20aaf558a25e93a4e6c4ec38a700b25c44d2434df780f9f&itok=2hA0x977)
ContributorsLi, Jing-Jing (Author) / Yin, Leijun (Author) / Johnson, Shane R. (Author) / Skromme, B. J. (Author) / Wang, Shumin (Author) / Liu, Xinyu (Author) / Ding, Ding (Author) / Ning, Cun-Zheng (Author) / Furdyna, Jacek K. (Author) / Zhang, Yong-Hang (Author)
Created2012
![130237-Thumbnail Image.png](https://d1rbsgppyrdqq4.cloudfront.net/s3fs-public/styles/width_400/public/2021-04/130237-Thumbnail%20Image.png?versionId=Ia6zQYPoft9pxRVbNtOSFWulJJwmyON5&X-Amz-Content-Sha256=UNSIGNED-PAYLOAD&X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Credential=AKIASBVQ3ZQ42ZLA5CUJ/20240616/us-west-2/s3/aws4_request&X-Amz-Date=20240616T004258Z&X-Amz-SignedHeaders=host&X-Amz-Expires=120&X-Amz-Signature=fa3459db2ec8d148cbd386191c23e7e759616ac0d70ffb27b53a02e4d038d260&itok=3wcAW7zH)
ContributorsHossain, N (Author) / Hild, Konstanze (Author) / Jin, S. R. (Author) / Yu, S.-Q. (Author) / Johnson, Shane R. (Author) / Ding, Ding (Author) / Zhang, Yong-Hang (Author) / Sweeney, S. J. (Author)
Created2013
![130238-Thumbnail Image.png](https://d1rbsgppyrdqq4.cloudfront.net/s3fs-public/styles/width_400/public/2021-04/130238-Thumbnail%20Image.png?versionId=FqdV.XJHGqoTlJBGxbuOOcYlb.tJJE0l&X-Amz-Content-Sha256=UNSIGNED-PAYLOAD&X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Credential=AKIASBVQ3ZQ42ZLA5CUJ/20240616/us-west-2/s3/aws4_request&X-Amz-Date=20240616T004258Z&X-Amz-SignedHeaders=host&X-Amz-Expires=120&X-Amz-Signature=19d07e33e1e0646350c7a331fa279fe2340c2df2d7e4f11654bc80246c7f6f1d&itok=L3Yqi21C)
ContributorsLiu, Shi (Author) / Li, Hua (Author) / Cellek, Oray O. (Author) / Ding, Ding (Author) / Shen, Xiao-Meng (Author) / Lin, Zhi-Yuan (Author) / Steenbergen, Elizabeth H. (Author) / Fan, Jin (Author) / He, Zhao-Yu (Author) / Lu, Jing (Author) / Johnson, Shane R. (Author) / Smith, David J. (Author) / Zhang, Yong-Hang (Author)
Created2013
![130244-Thumbnail Image.png](https://d1rbsgppyrdqq4.cloudfront.net/s3fs-public/styles/width_400/public/2021-04/130244-Thumbnail%20Image.png?versionId=BiZnl7q0guoHwG1kaUlyA4Pw46jCKU_q&X-Amz-Content-Sha256=UNSIGNED-PAYLOAD&X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Credential=AKIASBVQ3ZQ42ZLA5CUJ/20240616/us-west-2/s3/aws4_request&X-Amz-Date=20240616T004258Z&X-Amz-SignedHeaders=host&X-Amz-Expires=120&X-Amz-Signature=bad476e18686a5a41f96b5b34cf9e204bd0e362300d3a44b6720091f85e67e62&itok=Y495zrdp)
ContributorsWebster, Preston T. (Author) / Riordan, Nathaniel A. (Author) / Gogineni, Chaturvedi (Author) / Liu, Shi (Author) / Lu, Jing (Author) / Zhao, Xin-Hao (Author) / Smith, David J. (Author) / Zhang, Yong-Hang (Author) / Johnson, Shane R. (Author)
Created2014
![130270-Thumbnail Image.png](https://d1rbsgppyrdqq4.cloudfront.net/s3fs-public/styles/width_400/public/2021-04/130270-Thumbnail%20Image.png?versionId=YWNgEwZ2.97XEslTr4xNKmSmiQp_YE6y&X-Amz-Content-Sha256=UNSIGNED-PAYLOAD&X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Credential=AKIASBVQ3ZQ42ZLA5CUJ/20240615/us-west-2/s3/aws4_request&X-Amz-Date=20240615T214513Z&X-Amz-SignedHeaders=host&X-Amz-Expires=120&X-Amz-Signature=f177fdb12d2aefdc293276d319ccf8430f6dbe7f536e7d41f51107c5d2f5f759&itok=YfTLZqld)
Description
X-ray diffraction patterns from two-dimensional (2-D) protein crystals obtained using femtosecond X-ray pulses from an X-ray free-electron laser (XFEL) are presented. To date, it has not been possible to acquire transmission X-ray diffraction patterns from individual 2-D protein crystals due to radiation damage. However, the intense and ultrafast pulses generated by an XFEL permit a new method of collecting diffraction data before the sample is destroyed. Utilizing a diffract-before-destroy approach at the Linac Coherent Light Source, Bragg diffraction was acquired to better than 8.5 Å resolution for two different 2-D protein crystal samples each less than 10 nm thick and maintained at room temperature. These proof-of-principle results show promise for structural analysis of both soluble and membrane proteins arranged as 2-D crystals without requiring cryogenic conditions or the formation of three-dimensional crystals.
ContributorsFrank, Matthias (Author) / Carlson, David B. (Author) / Hunter, Mark S. (Author) / Williams, Garth J. (Author) / Messerschmidt, Marc (Author) / Zatsepin, Nadia (Author) / Barty, Anton (Author) / Benner, W. Henry (Author) / Chu, Kaiqin (Author) / Graf, Alexander T. (Author) / Hau-Riege, Stefan P. (Author) / Kirian, Richard A. (Author) / Padeste, Celestino (Author) / Pardini, Tommaso (Author) / Pedrini, Bill (Author) / Segelke, Brent (Author) / Seibert, M. Marvin (Author) / Spence, John (Author) / Tsai, Ching-Ju (Author) / Lane, Stephen M. (Author) / Li, Xiao-Dan (Author) / Schertler, Gebhard (Author) / Boutet, Sebastien (Author) / Coleman, Matthew (Author) / Evans, James E. (Author) / College of Liberal Arts and Sciences (Contributor) / Department of Physics (Contributor)
Created2014-02-28
![130185-Thumbnail Image.png](https://d1rbsgppyrdqq4.cloudfront.net/s3fs-public/styles/width_400/public/2021-04/130185-Thumbnail%20Image.png?versionId=Pj63WOrF.9gGLDiW3FxABQQnCsCtfYYF&X-Amz-Content-Sha256=UNSIGNED-PAYLOAD&X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Credential=AKIASBVQ3ZQ42ZLA5CUJ/20240615/us-west-2/s3/aws4_request&X-Amz-Date=20240615T081616Z&X-Amz-SignedHeaders=host&X-Amz-Expires=120&X-Amz-Signature=01db142637bebd472cadcaab3680565a01504bce23595475cdce034e211ddad8&itok=_56MHySv)
ContributorsBeaudoin, M. (Author) / Johnson, Shane R. (Author) / Boonzaayer, Martin D. (Author) / Zhang, Yong-Hang (Author) / Johs, B. (Author)
Created1999
![130186-Thumbnail Image.png](https://d1rbsgppyrdqq4.cloudfront.net/s3fs-public/styles/width_400/public/2021-04/130186-Thumbnail%20Image.png?versionId=hXEj0su92m05uTDYsbWEnf8ely4_IL36&X-Amz-Content-Sha256=UNSIGNED-PAYLOAD&X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Credential=AKIASBVQ3ZQ42ZLA5CUJ/20240616/us-west-2/s3/aws4_request&X-Amz-Date=20240616T035819Z&X-Amz-SignedHeaders=host&X-Amz-Expires=120&X-Amz-Signature=24fc65eec414fa0e36bd885010138e64b5e40f44cb7978e880cc830bdc6e69c5&itok=Qx9x3JBR)
ContributorsJohnson, Shane R. (Author) / Grassi, E. (Author) / Beaudoin, M. (Author) / Boonzaayer, Martin D. (Author) / Tsakalis, K. S. (Author) / Zhang, Yong-Hang (Author)
Created1999
![130187-Thumbnail Image.png](https://d1rbsgppyrdqq4.cloudfront.net/s3fs-public/styles/width_400/public/2021-04/130187-Thumbnail%20Image.png?versionId=9O4btb8Fx5pG_bzH6EDZM8pRL6cEuEuc&X-Amz-Content-Sha256=UNSIGNED-PAYLOAD&X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Credential=AKIASBVQ3ZQ42ZLA5CUJ/20240616/us-west-2/s3/aws4_request&X-Amz-Date=20240616T004258Z&X-Amz-SignedHeaders=host&X-Amz-Expires=120&X-Amz-Signature=46b3c979ad104540fc2d6aaeb77f49bc5687eac067129a573197c941c9ae2e50&itok=cBP-3V9_)
ContributorsBraun, W. (Author) / Möller, H. (Author) / Johnson, Shane R. (Author) / Zhang, Yong-Hang (Author)
Created1999
![130189-Thumbnail Image.png](https://d1rbsgppyrdqq4.cloudfront.net/s3fs-public/styles/width_400/public/2021-04/130189-Thumbnail%20Image.png?versionId=gb1Onr1xoUPHS9yyVJRHR8FCgc7sz65Z&X-Amz-Content-Sha256=UNSIGNED-PAYLOAD&X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Credential=AKIASBVQ3ZQ42ZLA5CUJ/20240616/us-west-2/s3/aws4_request&X-Amz-Date=20240616T014034Z&X-Amz-SignedHeaders=host&X-Amz-Expires=120&X-Amz-Signature=46952381c27b5c97805a9aa9f5a281d5976894f5b27a9b8c39a232fc2b9e21dd&itok=CJ4dRuvL)
ContributorsDowd, P. (Author) / Braun, W. (Author) / Smith, David J. (Author) / Ryu, C. M. (Author) / Guo, C.-Z. (Author) / Chen, S.-L. (Author) / Koelle, U. (Author) / Johnson, Shane R. (Author) / Zhang, Yong-Hang (Author)
Created1999