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- Creators: Barrett, The Honors College
- Creators: Debussy, Claude, 1862-1918
Description
Electrical stimulation can be used to activate peripheral nerve fibers to restore sensation to individuals with amputation and the technique is also being investigated as a means of treating a wide range of diseases. Longitudinal intrafascicular electrodes (LIFEs) are one of several types of electrodes that have been used to activate peripheral nerves. LIFEs can be used to activate small groups of fibers within a peripheral nerve fascicle, but the degree of their selectivity is uncertain. To investigate the effects of intrafascicular stimulation on nerve fiber activation, a mathematical, conductance-based model of an axon drawn from the literature was implemented and used to simulate the firing response of sensory nerve fibers in the presence of an applied monopolar electric field. Several axons were simulated to represent axons of different size, conductivity, spatial composition and location with respect to the electrode. Electric field profiles produced by pulses of different pulse widths and pulse amplitudes were created. Each fiber was placed within each resulting electric field and the firing threshold was determined. The effects of changes in pulse width, pulse amplitude, and distance on firing patterns were shown; all of these results were consistent with published experimental findings. The models showed lower firing threshold for smaller fibers than larger fibers and for fibers that were farther from the stimulating electrode than those that were closer. Firing threshold was also lower for stimuli of greater pulse width. Analysis of axon recruitment upon increases in pulse amplitude showed that the effects of fiber distance may be more pronounced than the effects of fiber size. This model can serve as a basis for further development to more accurately represent the effects of LIFEs and eventually may assist in the design of stimulation paradigms and waveforms to improve selectivity of axon activation when using LIFEs.
ContributorsSira, Alarmel (Author) / Abbas, James (Thesis director) / Crook, Sharon (Committee member) / Harrington Bioengineering Program (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
This research evaluated soft robotic knee brace designs that were intended to reduce the risk of injury, chronic pain, and osteoarthritis in laborers tasked with repetitive lifting. A soft robotic quasi-passive system was proposed due to energy efficiency, comfortability, and weight. The researcher developed three quasi-passive knee brace systems that would store energy when the user attempted a squat lift and release the energy when the user stood up. The first design focused on using clamped layered leaf springs to create an increased resistive force when the user bends at the knee. The researchers found that because of the unideal clamping of the springs the design failed to produce a significant increase to the forces the user experienced. The second design used a change in length of the layered leaf springs to provide a significant change in force. Through simple tests, the researchers found that the design did create a change in force significant enough to warrant further testing of the design in the future. The third and final design was inspired by a previous honors thesis by Ryan Bellman, this design used pre-stretched elastic bands to create an increased bending moment. Through experimental testing, the researchers found that the elastic bands created a factor increase of 8 from a non-loaded test. Further work would include prototyping a knee brace design and developing a method to allow the user to stretch and unstretch the elastic bands at will. In conclusion, design 2 and design 3 have the potential to significantly increase the well being of workers and increase their knee longevity.
ContributorsLewis, Kyle Jason (Co-author) / Lewis, Kyle (Co-author) / Sugar, Thomas (Thesis director) / Redkar, Sangram (Committee member) / Human Systems Engineering (Contributor) / Engineering Programs (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
The prevalence of excessive weight gain (obesity) has steadily increased since about 1980. Excessive weight gain is associated with many comorbidities; thus, a successful treatment is needed. The most common form of non-surgical treatment for excessive weight gain is caloric restriction with the intent to reduce body weight by 10%. Though this treatment is successful at reducing body weight, it often fails at maintaining the weight loss. Dietary menthol has been suggested as a possible treatment for excessive weight gain and has produced promising results as a preventative method for excessive weight gain. Our studies aimed at reducing weight regain and maintaining caloric restriction by feeding male Sprague-Dawley rats 0.5% dietary menthol during a period of caloric restriction, aimed at reducing their body weight by 10%, following an experimental period where the rats were fed a high-fat diet (HFD) or low-fat diet (LFD). The effects of the dietary menthol were observed during the weight regain period following the caloric restriction period. Two studies were conducted, and both were unable to achieve a maintenance of weight loss following caloric restriction, although our first study was able to produce a delay in weight regain and did not show any evidence of increased thermogenesis in menthol-treated rats. Our findings differ from the findings of previous studies on dietary menthol which could possibly be due to species effects, differences in procedures, age effects, or effects of different fatty acid compositions. The contrasting results in our studies could be due to genetic differences between litters used or a difference in manufacturing of the menthol diet between studies. Given the partial response to menthol in the first study, it can be suggested that the concentration of 0.5% may be below the threshold of menthol sensitivity for some rats. Future research should focus on increasing the concentration of dietary menthol from 0.5% to 1%, since the current concentration did not yield a reduction in weight regain or maintenance of caloric restriction.
ContributorsRascon, Kasandra (Author) / Herman, Richard (Thesis director) / Sweazea, Karen (Committee member) / Kim, Minjoo (Committee member) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
Approximately 1% of the total working population within the United States bikes as their primary mode of commute. Due to recent increased in bicycle facilities as well as a focus on alternative modes of transport, understanding the motivations and type of people who bike to work is important in order to encourage new users.
In this project, a literature review was completed as well as data analysis of the National Household Travel Survey (NHTS) in order to find specific populations to target. Using these target populations, it is suggested that advertising and workplace encouragement occur to persuade more people to bike to work. Through data analysis it was found that the most impactful variables were the region of the country, gender, population density, and commute distance. Bicycle commuters statistically had fewer vehicles in their households and drove less miles annually.
There were five main target groups found through this analysis; people who bike for other reasons besides work and live in a city with more than 4,000 people per square mile, young professionals between 19-39, women in regions with separated bicycle facilities, those with low vehicle availability, and environmentally conscious individuals. Working to target these groups through advertising campaigns to encourage new users, as well as increasing and improving bicycle facilities, will help create more new bicyclists.
In this project, a literature review was completed as well as data analysis of the National Household Travel Survey (NHTS) in order to find specific populations to target. Using these target populations, it is suggested that advertising and workplace encouragement occur to persuade more people to bike to work. Through data analysis it was found that the most impactful variables were the region of the country, gender, population density, and commute distance. Bicycle commuters statistically had fewer vehicles in their households and drove less miles annually.
There were five main target groups found through this analysis; people who bike for other reasons besides work and live in a city with more than 4,000 people per square mile, young professionals between 19-39, women in regions with separated bicycle facilities, those with low vehicle availability, and environmentally conscious individuals. Working to target these groups through advertising campaigns to encourage new users, as well as increasing and improving bicycle facilities, will help create more new bicyclists.
ContributorsImbus, Eileen Elizabeth (Author) / Khoeini, Sara (Thesis director) / Pendyala, Ram (Committee member) / Civil, Environmental and Sustainable Eng Program (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
Peasant communities on the Italian Peninsula relied on local climate and geography to produce fruits, vegetables, and grains. Over centuries, these peasant communities developed a system of food practices which became part of an integrative lifestyle people on the Italian Peninsula are still engaged in today. Through social and familial traditions that passed down through generations, these food practices were coined in the 20th century as the “Mediterranean Diet”. “Diet” in this context is defined by using the etymology of the Greek word ‘diaita’, which means “way of life”. The Mediterranean Diet represents a relationship with food, communities, and environments that promote health in several spaces. From peasant roots, the Mediterranean diet encourages the consumption of whole ingredients from fruits, vegetables, grains, and fish, with little emphasis on meats, poultries, and processed sugars, while also preparing and eating those foods with others. In the 21st century, these traditional food practices represent Personal, Social, and Environmental benefits which occur naturally from plant-based diets and socially minded eating practices. This thesis and creative project discusses the history, culture, science, and relevance of the traditional food practices of the Italian Peninsula and how it can be applied to one’s life. This is accomplished through a synthesis of comprehensive research related to the history and science of the Mediterranean Diet and its relationship to the body, society, and the environment, and engages the reader utilizing creative elements. This thesis encourages the reader to ask and answer the following questions: What does the food we eat mean in our lives? How does the food we eat reflect our values? How does our relationship with food affect our relationships with others? And how does the food we eat affect the world around us?
ContributorsPearce, Austen (Author) / Juliann, Vitullo (Thesis director) / John, Eaton (Committee member) / Department of Supply Chain Management (Contributor) / Department of Management and Entrepreneurship (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
In this research, the effect of the crystal structure of the parent phase on the morphology of nanoporous gold is explored. Specifically, Cu-Au alloys are studied. For this experiment, Cu0.75Au0.25 is heat treated to achieve an ordered phase Cu3Au and a disordered random solid solution, face centered cubic, Cu0.75Au0.25 phase, which are then dealloyed to form nanoporous gold (NPG). Using a morphology digital image analysis software called AQUAMI, SEM images of the NPG morphology were characterized to collect data on the ligament length, ligament diameter, porosity size, etc. of the samples. It was determined that the NPG formed from the ordered parent phase had an average ligament diameter that was 10 nm larger than the NPG formed from the disordered parent phase. This may be due to the ordered crystal structure allowing for faster gold diffusion and coarsening resulting in an increased average ligament size. Further future work is needed in order to obtain further evidence to support this hypothesis.
ContributorsTse, Ariana Yusof (Author) / Sieradzki, Karl (Thesis director) / Wang, Qing Hua (Committee member) / Materials Science and Engineering Program (Contributor) / Walter Cronkite School of Journalism & Mass Comm (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
Directors make choices on how a movie is film, these choices effect everything in the film and there are multiple factors that go into that decision-making process. Directors usually make decisions based on the entire story and their vantage point of know everything. For example, a director might choose to make a piece of information known to the audience before the character’s know so that it raises tension. The creative project refers to this type of filmmaking as: “objective cinema”. The alternative is when a director makes decisions not based on the overall story but on the reality of a character(s). That is, filmmaking techniques are used in service of communicating a character’s emotional and situational reality.
The goal of such an exercise is to bring the audience closer to a character, typically the main character. A film is driven by the audience’s connection to the plot and the main character, who is typically the driving force behind the narrative. Having an audience closer to the main character is advantageous to give the audience something personal to latch onto. Getting invested in a single character’s story is a tactic that most films use and while some use traditional filmmaking styles to narrate the film, some put in these subjective moments.
Most movies include a mix of objective and subjective scene; however, the vast majority of screen time is usually objective. Subjective moments are just that, moments within a film where the filmmaking is visually distinct from before in order to communicate the transition into a character’ subjective experience of reality. The process of using cinematic techniques: sound, images and actors to create emotion is the focus of the thesis. What specific techniques do director and other filmmakers use to create these moments from the perspective of a specific character? The research on this creative project included reverse engineering scenes to firgue out the technical specifications that the filmmakers use. What kind of lighting, cameras and sound design where employed? Why were those techniques chosen to represent a character’s subjective reality? And most importantly, why do those techniques evoke those emotions?
The goal of such an exercise is to bring the audience closer to a character, typically the main character. A film is driven by the audience’s connection to the plot and the main character, who is typically the driving force behind the narrative. Having an audience closer to the main character is advantageous to give the audience something personal to latch onto. Getting invested in a single character’s story is a tactic that most films use and while some use traditional filmmaking styles to narrate the film, some put in these subjective moments.
Most movies include a mix of objective and subjective scene; however, the vast majority of screen time is usually objective. Subjective moments are just that, moments within a film where the filmmaking is visually distinct from before in order to communicate the transition into a character’ subjective experience of reality. The process of using cinematic techniques: sound, images and actors to create emotion is the focus of the thesis. What specific techniques do director and other filmmakers use to create these moments from the perspective of a specific character? The research on this creative project included reverse engineering scenes to firgue out the technical specifications that the filmmakers use. What kind of lighting, cameras and sound design where employed? Why were those techniques chosen to represent a character’s subjective reality? And most importantly, why do those techniques evoke those emotions?
ContributorsKaufman, Jacob Aryeh (Author) / Collis, Adam (Thesis director) / Klucsarits, Philip (Committee member) / Lawrence, Sher (Committee member) / School of Film, Dance and Theatre (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
This Creative Project was carried out in coordination with the capstone project, Around the Corner Imaging with Terahertz Waves. This capstone project deals with a system designed to implement Around the Corner, or Non Line-of-Sight (NLoS) Imaging. This document discusses the creation of a GUI using MATLAB to control the Terahertz Imaging system. The GUI was developed in response to a need for synchronization, ease of operation, easy parameter modification, and data management. Along the way, many design decisions were made ranging from choosing a software platform to determining how variables should be passed. These decisions and considerations are discussed in this document. The resulting GUI has measured up to the design criteria and will be able to be used by anyone wishing to use the Terahertz Imaging System for further research in the field of Around the Corner or NLoS Imaging.
ContributorsWood, Jacob Cannon (Author) / Trichopoulos, Georgios (Thesis director) / Aberle, James (Committee member) / Electrical Engineering Program (Contributor) / School of Mathematical and Statistical Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
Honeybees are important pollinators worldwide and pollinate about one-third of the food we consume. Recently though, honeybee colonies have been under increasing stress due to changing environments, pesticides, mites, and viruses, which has increased the incidence of
colony collapse. This paper aims to understand how these different factors contribute to the decline of honeybee populations by using two separate approaches: data analysis and mathematical modeling. The data analysis examines the relative impacts of mites, pollen, mites, and viruses on honeybee populations and colony collapse. From the data, low initial bee populations lead to collapse in September while mites and viruses can lead to collapse in December. Feeding bee colonies also has a mixed effect, where it increases both bee and mite populations. For the model, we focus on the population dynamics of the honeybee-mite interaction. Using a system of delay differential equations with five population components, we find that bee colonies can collapse from mites, coexist with mites, and survive without them. As long as bees produce more pupa than the death rate of pupa and mites produce enough phoretic mites compared to their death rates, bees and mites can coexist. Thus, it is possible for honeybee colonies to withstand mites, but if the parasitism is too large, the colony will collapse. Provided
this equilibrium exists, the addition of mites leads to the colony moving to the interior equilibrium. Additionally, population oscillations are persistent if they occur and are connected to the interior equilibrium. Certain parameter values destabilize bee populations, leading to large
oscillations and even collapse. From these parameters, we can develop approaches that can help us prevent honeybee colony collapse before it occurs.
colony collapse. This paper aims to understand how these different factors contribute to the decline of honeybee populations by using two separate approaches: data analysis and mathematical modeling. The data analysis examines the relative impacts of mites, pollen, mites, and viruses on honeybee populations and colony collapse. From the data, low initial bee populations lead to collapse in September while mites and viruses can lead to collapse in December. Feeding bee colonies also has a mixed effect, where it increases both bee and mite populations. For the model, we focus on the population dynamics of the honeybee-mite interaction. Using a system of delay differential equations with five population components, we find that bee colonies can collapse from mites, coexist with mites, and survive without them. As long as bees produce more pupa than the death rate of pupa and mites produce enough phoretic mites compared to their death rates, bees and mites can coexist. Thus, it is possible for honeybee colonies to withstand mites, but if the parasitism is too large, the colony will collapse. Provided
this equilibrium exists, the addition of mites leads to the colony moving to the interior equilibrium. Additionally, population oscillations are persistent if they occur and are connected to the interior equilibrium. Certain parameter values destabilize bee populations, leading to large
oscillations and even collapse. From these parameters, we can develop approaches that can help us prevent honeybee colony collapse before it occurs.
ContributorsSweeney, Brian Felix (Author) / Kang, Yun (Thesis director) / Mubayi, Anuj (Committee member) / College of Integrative Sciences and Arts (Contributor) / Economics Program in CLAS (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
After the First World War, citizens, soldiers, and political figures alike thought they had witnessed the archetype of human sadism and war brutality. Yet, less than twenty years later, World War II immediately countered this notion. World War II was a transnational conflict that epitomized total war, which directly engaged civilians in the conflict like never before. Typically when we discuss Germany’s involvement in the war, we have visions of Hitler and his high-up officials personally crafting the Holocaust that killed 6 million Jews via firing squads, ghettoes, and gas chambers. The post-war landscape furthered this notion through the Nuremberg trials, which sentenced the most evil of the war’s perpetrators on the international stage, and the denazification process by the allied countries, which worked to reteach a “brainwashed” generation of Germans. However, rarely was the role of ordinary soldiers and the people at home a part of the dialogue of German complicity. Through the phases of post-war memorialization, people began to question the roles of themselves, and eventually their ancestors, in various ways. Of course, there are immense differences between the architect of the Final Solution and a Wehrmacht soldier who was drafted into the war; my goal is not to place these people on a ladder of guilt, but to widen the dialogue on the complex role ordinary Germans held during the war.
I will begin by establishing complicity among Wehrmacht soldiers, and then among ordinary people, contrasting beneficiaries and participants in popularized crime with bystanders. I will also argue that as women suffered uniquely during World War II, they also exercised unique complicity. Next, I will take these findings and discuss the memorialization of complicity in order to understand how individuals, the public, and the state framed their respective roles in the war; in order to accomplish this I will first discuss individual remembrance by examining individual interviews and familial interviews in order to gain an understanding of how people perceive their role in the war and also how individual stories can change as generations pass. These interviews include people who were both beneficiaries and bystanders. Then, I will discuss collective remembrance by examining the controversy over public monuments. Ultimately, I will argue that ordinary Germans all held significant levels of complicity that need to be assessed in order to understand the Nazi war effort and political system; additionally, how complicity is remembered greatly and profoundly affects memorialization and our future.
I will begin by establishing complicity among Wehrmacht soldiers, and then among ordinary people, contrasting beneficiaries and participants in popularized crime with bystanders. I will also argue that as women suffered uniquely during World War II, they also exercised unique complicity. Next, I will take these findings and discuss the memorialization of complicity in order to understand how individuals, the public, and the state framed their respective roles in the war; in order to accomplish this I will first discuss individual remembrance by examining individual interviews and familial interviews in order to gain an understanding of how people perceive their role in the war and also how individual stories can change as generations pass. These interviews include people who were both beneficiaries and bystanders. Then, I will discuss collective remembrance by examining the controversy over public monuments. Ultimately, I will argue that ordinary Germans all held significant levels of complicity that need to be assessed in order to understand the Nazi war effort and political system; additionally, how complicity is remembered greatly and profoundly affects memorialization and our future.
ContributorsTobin, Janna K (Author) / Benkert, Volker (Thesis director) / Cichopek-Gajraj, Anna (Committee member) / Historical, Philosophical & Religious Studies (Contributor) / Economics Program in CLAS (Contributor) / School of Politics and Global Studies (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2019-05