Matching Items (23)
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Suicide is one of the leading causes of death worldwide and statistical analysis of suicide by profession reveals that physicians and veterinarians experience abnormally high suicide rates. This paper seeks to provide a comprehensive literature review over what some general theories of suicide are, why these professions exhibit high suicide

Suicide is one of the leading causes of death worldwide and statistical analysis of suicide by profession reveals that physicians and veterinarians experience abnormally high suicide rates. This paper seeks to provide a comprehensive literature review over what some general theories of suicide are, why these professions exhibit high suicide rates, what assistance is currently being provided, and where do these assistance efforts succeed or fail. Moreover, this paper addresses what advancements may be made within these fields to further combat suicide in physicians and veterinarians. To achieve this, general theories behind suicide, risk factors unique to or heavily prevalent in these professions, and current assistance efforts are read, organized, and summarized.<br/><br/>A summary of these risk factors includes stress and mental health disorders accumulated through school and work, personal and professional isolation, access to lethal substances, suicide contagion, exposure to euthanasia, and the role of perfectionism. There are several assistance efforts in place with the most successful ones being highly personalized, but many are still underutilized. Moreover, the stigma of suicide pervades these professions and is addressed by several researchers as something to combat or prevent. Going forward, it is hopeful that not only will more assistance efforts will be created and provided for physicians and veterinarians suffering from suicidal tendencies, but efforts to reduce the stigma of suicide be implemented and utilized as soon as possible.

ContributorsSinclair, Andrew (Author) / DeNardo, Dale (Thesis director) / Sterner, Beckett (Committee member) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
Description

Hemcrete is an alternative, environmentally‐friendly building material gaining adherents in Great Britain and other European countries. It is an attractive choice as a building material because it is made from a renewable resource, hemp, a hardy plant that is a close, but non‐hallucinogenic relative of marijuana. This plant is relatively easy to cultivate,

Hemcrete is an alternative, environmentally‐friendly building material gaining adherents in Great Britain and other European countries. It is an attractive choice as a building material because it is made from a renewable resource, hemp, a hardy plant that is a close, but non‐hallucinogenic relative of marijuana. This plant is relatively easy to cultivate, requires little in the way of pesticides or fertilizers, and almost all parts can be used for various products from paper to textiles to food.

Hemcrete is made from a mixture of lime, water, and the fibrous outer portion of the hemp plant called the “hurd” or “shive”. When mixed, it is worked and placed much like conventional concrete ‐ hence the name. However, that is where the similarities with concrete end. Hemcrete is not comparable to concrete on a strength basis, and is better described as an alternative insulation product. When built into walls of sufficient thickness, Hemcrete offers high thermal efficiency, and has strong claims to being carbon negative. The purpose of this study
was to evaluate this claim of carbon negativity, and to compare these environmentally friendly qualities against conventional fiberglass batt insulation.

Our model was constructed using two identically sized “walls” measuring eight feet square by one foot in depth, one insulated using Hemcrete, and the other using fiberglass. Our study focused on three areas: water usage, cost, and carbon dioxide emissions. We chose water
usage because we wanted to determine the feasibility of using Hemcrete in the Phoenix metropolitan region where water is a troubled resource. Secondly, we wished to evaluate the claim on carbon negativity, so CO2 equivalents throughout the production process were measured. Finally, we wished to know whether Hemcrete could compete on a cost basis with more conventional insulation methods, so we also built in a price comparison.

Since the cultivation of hemp is currently unlawful in the United States, this study can help determine whether these restrictions should be relaxed in order to allow the construction of buildings insulated with Hemcrete.

Created2013-05
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Humans have evolved in many ways. Just look at how life for mankind has changed over the past few decades. It is amazing how different life can be in just a short amount of time. While it is evident that we have impacts of the environment, it should be just

Humans have evolved in many ways. Just look at how life for mankind has changed over the past few decades. It is amazing how different life can be in just a short amount of time. While it is evident that we have impacts of the environment, it should be just as evident that we impact the animals around us. However, there are a few subtle ways in which we impact the evolution of life.
Through man-made structures, human interference, artificial lights at night, and electromagnetic fields we have caused animals and insects to evolve and fit these new environments. While we tail the world around us to convince ourselves, the animals also living in these environments need to adapt to survive. In this essay, I will discuss how the affects mentioned above have cause crows, moths, snails, bobcats, blackbirds, mosquitoes, elephants, diurnal animals, fireflies, dung beetles, birds and bats to evolve. The adaptations these organisms made were caused by the subtle ways in which we have impact the landscapes around us.
ContributorsFikse, Sydney D (Author) / Sterner, Beckett (Thesis director) / Pfeifer, Susanne (Committee member) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
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This thesis analyzes the implications of climate change for insect-borne diseases in humans, focusing especially on mosquitoes and ticks as the two most common vectors. I first introduce relevant background on climate change, arthropod vectors, and the diseases they carry, and the significance of vector-borne diseases for human health. I

This thesis analyzes the implications of climate change for insect-borne diseases in humans, focusing especially on mosquitoes and ticks as the two most common vectors. I first introduce relevant background on climate change, arthropod vectors, and the diseases they carry, and the significance of vector-borne diseases for human health. I report on current knowledge of spatial and temporal trends in most common mosquito and tick-borne diseases in the United States, with a detailed table provided in Appendix A. I then review how climatic variability is anticipated to cause profound changes in vector life cycles. In particular, the rise in global ambient temperatures is likely to be the primary driver of arthropod proliferation, although they are also sensitive to changes in humidity, carbon dioxide levels, and water levels. As regions warm, arthropods will be able to survive where they were not able to previously, potentially infecting more individuals. The incidence of several vector-borne diseases in the United States is predicted to increase in multiple states as climate change progresses. The World Health Organization predicts that in North America, Dengue Hemorrhagic Fever and Lyme disease will become the primary vector-borne diseases that are increasingly common (Githeko, et. al, 2000).
ContributorsKarjala, Sylvia (Author) / Sterner, Beckett (Thesis director) / Jevtic, Petar (Committee member) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2020-12
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Animal testing is a long-running institution in biomedical research that is seen as a necessary step in the development of new drugs and treatments in the United States. Using animal models that have biological similarities to humans, it is assumed that we can ethically perform basic research that is translatable

Animal testing is a long-running institution in biomedical research that is seen as a necessary step in the development of new drugs and treatments in the United States. Using animal models that have biological similarities to humans, it is assumed that we can ethically perform basic research that is translatable to human health. However, recent years have seen this assumption challenged by the fact that most preclinical research fails to survive the gauntlet of human trials into a functioning treatment on the market. This has marked ethical implications for both the people that depend on new treatments for their health, and the animals used in the research themselves. The purpose of this thesis is to develop solutions for the problems facing animal testing in the United States. First, I identify the political and economic basis of the modern system of animal testing by examining legislation and the IACUCs that govern animal research to understand why the practice continues to be used despite its low rate of success. I then examine factors such as epigenetics and the laboratory environment to explain reasons why animal research fails to translate to humans. Finally, I cover new in-vitro methods such as organoids and organ-on-a-chip technologies to show the potential that alternatives hold for biomedical research. As a result of this analysis, I propose the further integration of alternatives into our system of animal testing to make up for the translational failures the field currently experiences. I also highlight the importance of having IACUCs balanced between animal researchers and members of the public to improve the welfare of animals used in research and increase the transparency of their work. Including more animals into the Animal Welfare Act is also proposed to better standardize our treatment of them and keep experimental results more consistent.
ContributorsCammann, Davis Bukovi (Author) / Barca, Lisa (Thesis director) / Hurlbut, Ben (Committee member) / Sterner, Beckett (Committee member) / School of Life Sciences (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2020-12
Description

The status of Earth’s diversity is deteriorating quickly which will continue to impact humans’ way of life, as well as every other living creature, in all regions of the world. However, there are organizations taking action to protect biodiversity on our planet. The Convention on Biological Diversity (CBD) is one

The status of Earth’s diversity is deteriorating quickly which will continue to impact humans’ way of life, as well as every other living creature, in all regions of the world. However, there are organizations taking action to protect biodiversity on our planet. The Convention on Biological Diversity (CBD) is one of those organizations and includes 196 signatories from around the world who are committed to strategies to preserve their biodiversity (Secretariat). Indeed, 98% of the parties which have participated in the Convention on Biological Diversity (CBD) have created national biodiversity strategies (NBS) and action plans (NBSAPs) (Secretariat). Yet, there are still countries that have yet to partake in these efforts. America continues to hold out against ratifying the CBD and remains the only developed country without a National Biodiversity Strategy. As an NBS for the U.S. is under consideration, my goal is to understand what works from previous plans. In particular, I focus on stakeholder engagement in Conservation Biodiversity Action Plans. Stakeholder engagement is important because, without it, there may be insufficient levels of integration of the action plans, which can lead to the failure of the CBDs conservation efforts. To address this question, I analyze the 193 strategies created for countries across the globe. My review describes the ways that stakeholders are engaged in National Biodiversity Strategies for CBD member countries. All plans mention some form of engagement. The most common types mentioned are ‘Education’, ‘Communication’, and ‘Training’. Examining the plans further reveals that most forms of engagement often are just mentioned and not completed. Close to 58% of the engagement forms are only completed about 50% of the time. Exceptions are surveys, interviews, and workshops, which are each completed in over 70% of plans that mention them. I then use this information to provide practical recommendations for creating an effective NBSAP for the United States.

ContributorsOlofsson, Elisa (Author) / Gerber, Leah (Thesis director) / Kroetz, Kailin (Committee member) / Sterner, Beckett (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor)
Created2022-12
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Evolution is a key feature of undergraduate biology education: the AmericanAssociation for the Advancement of Science (AAAS) has identified evolution as one of the five core concepts of biology, and it is relevant to a wide array of biology-related careers. If biology instructors want students to use evolution to address scientific challenges post-graduation,

Evolution is a key feature of undergraduate biology education: the AmericanAssociation for the Advancement of Science (AAAS) has identified evolution as one of the five core concepts of biology, and it is relevant to a wide array of biology-related careers. If biology instructors want students to use evolution to address scientific challenges post-graduation, students need to be able to apply evolutionary principles to real-life situations, and accept that the theory of evolution is the best scientific explanation for the unity and diversity of life on Earth. In order to help students progress on both fronts, biology education researchers need surveys that measure evolution acceptance and assessments that measure students’ ability to apply evolutionary concepts. This dissertation improves the measurement of student understanding and acceptance of evolution by (1) developing a novel Evolutionary Medicine Assessment that measures students’ ability to apply the core principles of Evolutionary Medicine to a variety of health-related scenarios, (2) reevaluating existing measures of student evolution acceptance by using student interviews to assess response process validity, and (3) correcting the validity issues identified on the most widely-used measure of evolution acceptance - the Measure of Acceptance of the Theory of Evolution (MATE) - by developing and validating a revised version of this survey: the MATE 2.0.
ContributorsMisheva, Anastasia Taya (Author) / Brownell, Sara (Thesis advisor) / Barnes, Elizabeth (Committee member) / Collins, James (Committee member) / Cooper, Katelyn (Committee member) / Sterner, Beckett (Committee member) / Arizona State University (Publisher)
Created2023
Description
Scientific researchers have studied microorganisms since the emergence of the single lens microscope in the 17th century. Since then, researchers designed and published many thousands of images to record and share their observations, including hand-drawn diagrams, photomicrographs, and photographs. Images shaped how researchers conceived of microorganisms, their concepts of microorganisms

Scientific researchers have studied microorganisms since the emergence of the single lens microscope in the 17th century. Since then, researchers designed and published many thousands of images to record and share their observations, including hand-drawn diagrams, photomicrographs, and photographs. Images shaped how researchers conceived of microorganisms, their concepts of microorganisms shaped their images, and their images and concepts were shaped by the contexts in which they were working. Over time, the interplay of images and concepts in various research contexts participated in the development of new concepts related to microorganisms, like the “biofilm” concept, or the idea that bacteria exist in nature as complex aggregates attached to surfaces via extracellular polymeric matrices. Many histories of microbiology locate the origin of the biofilm concept in the 1970s, but that date obscures the rich history of research about attached microbial aggregates that occurred throughout the history of microbiology. I discovered how the interplay of images and concepts related to bacteria participated in the development of the biofilm concept by documenting when and why researchers used different visual features to represent changing concepts related to microorganisms. I specifically examined how and why scientists represented evolving concepts related to bacteria during the 17th century (Chapter 1), from the late 17th century to the early 20th century (Chapter 2), and during the first seventy-four years of the 20th century (Chapter 3). I discovered the biofilm concept developed in at least three unique research contexts during the 20th century, and how images reflected and shaped the concept’s development in each case. The narrative and collection of images generated from this work serve as a visual history of the development of scientists’ ideas about the nature of bacteria over 300 years.
ContributorsGuerrero, Anna Clemencia (Author) / Maienschein, Jane (Thesis advisor) / Laubichler, Manfred (Committee member) / Sterner, Beckett (Committee member) / Matlin, Karl (Committee member) / Arizona State University (Publisher)
Created2023
Description

An effort to experiment on the novel Usutu virus in pure in silico methods was made to determine conformational changes with non polar point mutations in the amino acid sequence. The first method consisted of creating a Python program to exhaustively identify codons, amino acids, and dinucleotide bridges & nonbridges,

An effort to experiment on the novel Usutu virus in pure in silico methods was made to determine conformational changes with non polar point mutations in the amino acid sequence. The first method consisted of creating a Python program to exhaustively identify codons, amino acids, and dinucleotide bridges & nonbridges, including viral characteristics defined by Mollentze in 2021. The second method consisted of creating point mutations to non polar amino acids in deemed key sites of the Usutu virus envelope protein and finding the RMSD from the original structure. This resulted in one of two outcomes - either the experiment showed that the Usutu virus envelope protein is highly resistant to point mutations or in silico methods are inconsistent and biased, leading to inaccuracy.

ContributorsBurton, Reilly (Author) / Mills, Jeremy (Thesis director) / Sterner, Beckett (Committee member) / Upham, Nathan (Committee member) / Barrett, The Honors College (Contributor) / Division of Teacher Preparation (Contributor) / School of Molecular Sciences (Contributor)
Created2023-05
Description

This study highlights the significance of zoonotic diseases, which make up almost 60% of infectious diseases in humans, and their origin from animals. Among mammalian viruses, primates, bats, and rodents have been identified as high-risk carriers. Within the rodent family Cricetidae, the species complex of Peromyscus eremicus, Peromyscus californicus, Peromyscus

This study highlights the significance of zoonotic diseases, which make up almost 60% of infectious diseases in humans, and their origin from animals. Among mammalian viruses, primates, bats, and rodents have been identified as high-risk carriers. Within the rodent family Cricetidae, the species complex of Peromyscus eremicus, Peromyscus californicus, Peromyscus fraterculus, and Osgoodomys banderanus have been found to play a crucial role in disease transmission. These four species are phylogenetically related and share similar physical appearances and ecological niches. They have been identified as carriers of several zoonotic diseases, including Hantavirus, Arenavirus, Yersinia pestis, and Flavivirus, with a history of spread to humans. Despite their implications for public health, many of these species remain understudied. Thus, this study aims to provide a systematic review of the existing literature on these four species to summarize the findings on virus prevalence and distribution. The review shows that sampling efforts have been uneven and recent efforts have been lacking, with potential undiscovered zoonotic diseases. The concentration of sampling efforts in California and gaps in the literature are concerning, especially with changing agriculture and climate change potentially affecting rodent communities.

ContributorsTariq, Muhamamad (Author) / Sterner, Beckett (Thesis director) / Upham, Nate (Committee member) / Barrett, The Honors College (Contributor) / Dean, W.P. Carey School of Business (Contributor) / School of Life Sciences (Contributor)
Created2023-05