Matching Items (314)
Description
Patients who are infected with the human immunodeficiency virus (HIV) and who remain adherent to their highly active antiretroviral treatment (HAART) regimen are likely to achieve good virologic control over significant periods of time. Children who start with a low CD4 percentage (below 15%) are associated with adverse clinical outcomes and the risk of never increasing their CD4 counts to normal functioning levels. While adherent adult HIV patients have been studied frequently, this was a retrospective chart study that aimed to describe the immune reconstitution pattern for up to 16 years in virologically controlled pediatric patients who had been or who are currently being treated at the Bill Holt Clinic at Phoenix Children's Hospital. In the preliminary study, 35 patients met criteria for inclusion and three years later for this extension study 7 more were added while 17 of the initial patients were followed further because they have remained in care and virologically controlled. All 28 patients who achieved 5 years of viral suppression were >25% CD4. All 8 patients who achieved 12 years of viral suppression were >31% CD4. All patients who achieved 16 years of viral suppression were >41% CD4. After 12 years, the 8 patients who maintained viral suppression all had absolute CD4 counts of over 600 cells and additionally each had CD4/CD8 ratios greater than 1. Overall, the data shows immune system normalization for up to 16 years, although CD4/CD8 ratios improved but never completely normalized. Some limitations include a small sample size and missing data points due to laboratory testing errors or the lack of technology in different countries to test for CD8 cells. These findings suggest that children who remain adherent to HAART can experience ongoing immune healing for up to 16 years. This may provide additional incentive to providers and caretakers to encourage adherence and maximize long-term immune competence in HIV positive children.
ContributorsRichards, Anne Elizabeth (Author) / Wachter, Rebekka (Thesis director) / Blattman, Joseph (Committee member) / Barrett, The Honors College (Contributor) / Department of Chemistry and Biochemistry (Contributor) / School of Human Evolution and Social Change (Contributor)
Created2015-05
Description
Waste generation in the U.S. has reached new heights, but the exploitation of Native American lands for waste disposal is nothing new. Many of the negative effects of massive waste production and toxic pollution, such as poor health outcomes and decreased property values, disproportionately burden impoverished, minority communities inside and outside the United States (Brulle and Pellow, 2006). Native American communities have long been exploited for their natural resources and land-use, but in recent decades Indian country has also become a common place to store nuclear, hazardous and municipal wastes. This project is a case study of a local Indian reservation, the Salt River Pima-Maricopa Indian Community, and examined the socio-historical context of the landfill operations in terms of five principles of environmental justice. Each principle was defined and key moments from the SRPMIC's landfill history were discussed to demonstrate ways that the situation has improved, stayed the same or worsened with regard to the rights outlined in each principle. It was concluded that there needs to be an acknowledgement by involved municipalities and industries of the historical context that make the SRPMIC and other nearby Native American communities "ideal" contractors for waste management. Additionally, while the SRPMIC could currently benefit from looking into the principles of environmental justice as a guide to manage past and operating landfills, the Community will have a specific opportunity to revisit these issues under closer scrutiny during the closure of the Salt River Landfill in 2032 in order to ensure more environmentally just outcomes. Finally, it was concluded that scholarship at the intersection of environmental justice and Native American communities should continue because looking closer at the ways that local Native American communities are facing and resisting environmental injustice can serve to develop future models for other communities facing similar challenges to achieving environmental justice.
ContributorsScott, Nicole Danielle (Author) / Kinzig, Ann (Thesis director) / Harlan, Sharon (Committee member) / Maienschein, Jane (Committee member) / Barrett, The Honors College (Contributor) / School of Community Resources and Development (Contributor) / School of Social Transformation (Contributor) / School of Human Evolution and Social Change (Contributor)
Created2015-05
Description
With an increasing global interest in Chinese economics and society, more and more native English speakers have started to learn Chinese as a second language (L2). While English and Chinese share a similar word order at the syntactic level, they differ significantly in ways to keep track of reference at the discourse level. There are generally three ways to keep track of reference: repeating the full noun phrase (NP), replacing the full NP with a lexical pronoun, or omitting the NP using zero anaphora. Chinese, a topic-prominent language, allows a wide use of zero anaphora to maintain reference; whereas English, a subject-prominent language, allows only a limited use of zero anaphora. Due to this difference, Chinese as a second language learners whose native language is English (CSL learners), must learn to implement the use of zero anaphora more frequently in their Chinese discourse. The purpose of this study is to investigate how CSL learners keep track of reference using zero anaphora. It is hypothesized that CSL learners at intermediate proficiency level would display a transfer effect from English to Chinese in their Chinese discourse. Specifically, they would produce fewer zero anaphora than native Chinese speakers, and they would also tend to consider discourse with many uses of zero anaphora for reference tracking as less appropriate. To test the hypothesis, a story-retelling task and multiple-choice questions task were adopted. The results of both tasks supported the hypothesis. Meanwhile, it is also evident that the CSL learners have acquired some usage of zero anaphora in their Chinese discourse as the usage of zero anaphora was more frequent when speaking Chinese than English.
ContributorsTang, Tianyu (Co-author) / Abdulla, Farzana (Co-author) / Chien, Jasmine (Co-author) / Zhang, Xia (Thesis director) / Bahtchevanova, Mariana (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor) / School of International Letters and Cultures (Contributor) / School of Human Evolution and Social Change (Contributor) / Department of Supply Chain Management (Contributor)
Created2015-05
Description
This paper explains what factors influence mental health issues and what type of care is provided in various countries. The countries in this study will include the United States, Japan, Ethiopia and South Africa, all of which have varying degrees of ethnic diversity, economic status and understanding of mental health issues. It discusses the specific healthcare systems in each country, as well as the attitudes and problems associated with depression and schizophrenia, two prevalent mental health disorders. This paper examines the different ways that a diagnosis is reached for schizophrenia and major depression in these different countries, as well as what methods are used for treating individuals with these disorders. It will also examine the prominent notion that schizophrenia has better outcomes in developing countries than in places that have wider medical care available. It then discusses what treatments are available in each country, as well as social constructs that exist regarding those treatments in order to understand the ways that treatments can be expanded to improve outcomes. This paper will then examine the different outcomes of these mental health disorders that are common in each country, and conclude with ideas on how to make global mental health a reality.
ContributorsOlsen, Rachel Lindsay (Author) / Gaughan, Monica (Thesis director) / Wood, Reed (Committee member) / Barrett, The Honors College (Contributor) / School of Politics and Global Studies (Contributor) / School of Human Evolution and Social Change (Contributor) / Department of Psychology (Contributor)
Created2015-05
Description
The study examines cross-cultural perceptions of wastewater reuse from 282 participants from four global sites representing varied levels of socio-economic and political development from the Global North and Global South: Spain, New Zealand, Fiji, and Guatemala. The data comes from the Global Ethnohydrology Survey conducted by the School of Human Evolution and Social Change during the summer of 2013. The Global Ethnohydrology Study is a transdisciplinary multi-year research initiative that examines the range of variation in local ecological knowledge of water issues, also known as "ethnohydrology." Participants were asked about their willingness, level of disgust, and concern with using treated wastewater for various daily activities. Additionally, they were asked to draw schematic representations of how wastewater should be treated to become drinkable again. Using visual content analysis, the drawings were coded for a variety of treatment levels and specific treatment processes. Conclusions about the perceived health implications from wastewater reuse that can stem from drinking treated wastewater were made. The relationship between humans and wastewater is one that has many direct social and health impacts on communities at large. In reaction to global limitations of freshwater, wastewater serves as a valuable resource to tap into. This research examines the cross-cultural public health concerns about treated wastewater in order to draw conclusions that can aid in strategic implementation of advocacy and public education about wastewater reuse.
ContributorsPatel, Sarah Shakir (Author) / Wutich, Amber (Thesis director) / Rice, Jacelyn (Committee member) / Barrett, The Honors College (Contributor) / School of Politics and Global Studies (Contributor) / School of Human Evolution and Social Change (Contributor)
Created2015-05
Description
Triops (Branchiopoda: Notostraca) and Streptocephalus (Branchiopoda: Anostraca) are two crustaceans which cohabitate in ephemeral freshwater pools. They both lay desiccation resistant eggs that disperse passively to new hydrologically isolated environments. The extent of genetic distance among regions and populations is of perennial interest in animals that live in such isolated habitats. Populations in six natural ephemeral pool habitats located in two different regions of the Sonoran Desert and a transition area between the Sonoran and Chihuahuan Deserts were sampled. Sequences from Genbank were used for reference points in the determination of species as well as to further identify regional genetic distance within species. This study estimated the amount of within and between genetic distance of individuals from each region and population through the use of a neutral marker, cytochrome oxidase I (COI). We concluded that, although the method of passive dispersal may differ between the two genera, the differences do not results in different patterns of genetic distances between regions and populations. Furthermore, we only found the putative species, Triops longicaudatus "short", with enough distinct speciation. Although Triops longicaudatus "long" and Triops newberryi may be in the early stages of speciation, this study does not find enough support to conclude that they have separated.
ContributorsMurphy Jr., Patrick Joseph (Author) / Rutowski, Ronald (Thesis director) / Cartwright, Reed (Committee member) / Lessios, Nikos (Committee member) / School of Life Sciences (Contributor) / School of Human Evolution and Social Change (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
This is a study of the adaptive behaviors of individuals with Autism Spectrum Disorder using the Vineland II Adaptive Behavioral Scale (VABS-II). This scale was used to determine the overall functioning level of individuals with Autism Spectrum Disorder at the beginning, and will be used at the end, of a year-long study beginning at Arizona State University. This larger study is determining what the effects are, if any, of a combination of nutritional and dietary treatments in individuals with Autism Spectrum Disorder. However, this paper only examines the VABS-II results of forty-three participants in the study, as well as their hand-grip strength. It was found that individuals with Autism Spectrum Disorder are substantially delayed in all four domains (communication, daily living skills, social skills, and motor skills) of adaptive behaviors measured by the VABS-II, particularly in communication. This study will be completed in May 2013, when it will be determined what the effects of these treatments are, if any.
ContributorsAdams, Rebecca (Author) / Ingram-Waters, Mary (Thesis director) / Krajmalnik-Brown, Rosa (Committee member) / Pollard, Elena (Committee member) / Barrett, The Honors College (Contributor)
Created2012-05
Description
Isotopic analyses of archaeological and modern materials are commonly used to reconstruct diet, climate, and habitat. This study analyzes 15 camelid samples from three sites (two archaeological, one modern) in South America to determine their carbon and nitrogen isotopic values to further explore the relationship between stable isotopes and environments. Camelid individuals in the modern site of Cuenca, Ecuador had a diet of almost entirely C3 vegetation, while those in Chen Chen, Peru had slightly higher values, still consistent with C3 plants. Those in the higher altitude site of Pumapunku, Bolivia had higher δ13C values than expected, indicating they may have been foddered with a mixed diet. These isotopic data indicate that vegetation, and therefore herbivore diets, are influenced by altitude. Additionally, it was found that a positive linear relationship exists between δ15N values and aridity of a site. Results indicate that aspects of the environment such as aridity are reflected in isotopic signatures. These results contribute to the increasing amount of data on isotopic variation in South American camelids, both modern and archaeological.
ContributorsSpencer, Katherine Clare (Author) / Knudson, Kelly (Thesis director) / Reed, Kaye (Committee member) / School of Human Evolution and Social Change (Contributor) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
During the summer of June 2014, the researcher, a non-traditional student, studied abroad in Fiji with Arizona State University's School of Human Evolution and Social Change leaving behind a family and financial responsibilities. The program was part of a growing trend as a short-term study abroad experience lasting only eight days. A service-learning project was completed at Votua Village on the Coral Coast which included a homestay and planting on the farm. An autoethnographical approach was used to describe this experience using a personal narrative written in first-person to evoke an emotional response. As a non-traditional student, the experience was probably profoundly different than it may have been for a majority of the class. The motivations, fears, and challenges associated with being a non-traditional student are discussed as well as the mother's guilt that many women experience when working outside of the home towards a personal achievement. The benefits of study abroad to non-traditional students is explained, as is the need for further research regarding their inclusion into these programs. Possible expansions of the study abroad program to include more of the non- traditional demographic within the student body at ASU are discussed. Several recommendations follow the narrative that may help to increase equitable access to study abroad for all students at the tertiary level. This work is a reflection on the researcher's experience as part of a diverse yet mostly traditional group of 35 students that made the trip to Fiji from a non-traditional student perspective and includes photographs as a visual autoethnography from the adventure to enhance and supplement the narrative.
ContributorsBell, Bridget Anne (Author) / Goodman, Rebekka (Thesis director) / Timothy, Dallen (Committee member) / School of Sustainability (Contributor) / School of Human Evolution and Social Change (Contributor) / School of Community Resources and Development (Contributor) / Barrett, The Honors College (Contributor)
Created2015-12
Description
This paper explores the complex, multifaceted relationship of science and science fiction. Because of our rapidly evolving, technology-driven world, the question of how science fiction changes, and is changed by, science is more relevant today than ever before. The nuanced relationship of science and science fiction can first be explored by analyzing the influence of science fiction on science with examples such as the XPRIZE Foundation. At the same time that science fiction influences science, changes in science will also resonate in the future of science fiction. New developments like the open-source movement and the success of platforms like Kickstarter, which allow science to be crowdsourced at unprecedented levels, are changing the landscape of scientific development. These changes are causing increased public engagement with science. Based on these changes in the way science and technology are developed, the science fiction genre seems on the cusp of a dramatic shift. Science fiction has long been dominated by dystopian and apocalyptic visions for the future, frequently the result of some catastrophe of our own making. However, because of the changes in science and technology and the public's engagement with those changes, the next generation of science fiction writers and filmmakers is likely to see a more positive outlook for humanity. Based on the interlocked past of science and science fiction, this paper argues that the changing landscape of science and technology will cause a change for the positive in the tonality of popular science fiction.
ContributorsMiller, Hillary Marie (Author) / Finn, Ed (Thesis director) / Swanner, Leandra (Committee member) / School of Film, Dance and Theatre (Contributor) / School of Human Evolution and Social Change (Contributor) / Barrett, The Honors College (Contributor)
Created2015-12