Introduction: As of 2016, medical errors were the third leading cause of death in the U.S1, costing over 250,000 deaths and 17 billion dollars annually.

1. Poor communication between patients and their providers leads to increased adverse effects that are primarily drug-drug interactions. Medical miscommunication leads to decreased treatment adherence, dissatisfaction, and inefficient use of resources.

13. Solutions to reduce the errors that arise from miscommunication in the healthcare field are medical transcription apps. HealthKeep by HealthKeep LLC is a medical transcription app that audio records and categorizes visit information and makes it readily accessible to patients, providers, caregivers, and immediate family members.

5. The aim of this study is to conduct a literature review of mHealth applications to identify the common reasons that influence consumers to discontinue use, or more importantly, continue using these applications. The final aim is to identify the market demand and needs of the consumers to ensure better acceptability of our HealthKeep app. Methodology. This literature review was conducted using the ASU library database. The ASU Library database pulls articles from various databases such as PubMed, ScienceDirect, and ProQuest. After applying the inclusion and exclusion criteria, 14 articles were found to be relevant.

Results: Overall, 14 pertinent articles were found through keyword searches. (Healthcare apps) AND (Marketing) - 3, Healthcare transcription apps - 2, Mobile Health Apps - 2, (Security Issues) AND (Healthcare apps) - 1, (gamification) AND (mobile apps) - 2, long term use of mobile health apps “Long term use” AND “ mobile health app” - 1, Medical Miscommunication - 3

Discussion: Top five user concerns were found to be: low awareness, lack of app literacy, cost, non user friendly, lack of security and privacy. Top five ways to foster continued use: social competition, rewards, gamification, convenience/transparency, increased functionality.

Conclusion: The keep strategies for increasing uptake and stickiness: cost friendly, increased app awareness, proper security measures, convenience and low effort, aesthetically pleasing. Healthkeeps future improvements: capture and manage accurate medication lists to reduce medical errors , integrate transcriptions into the EHR, incorporate rewards (tangible and intangible)

In order for microalgae to be a cost-effective renewable energy source, a high CO2-transfer efficiency (CTE) is necessary. Using hollow-fiber membranes (HFM), membrane carbonation (MC) in microalgal cultivation can be used to achieve a CTE near 100%. Due to the diurnal cycle in outdoor algal cultivation, an inconsistent CO2 demand with temperature fluctuations can cause pore wetting of the inner and outer fiber layers in composite HFMs. In addition, the presence of supersaturated O2 during high algal growth may change the gas transfer dynamics of the fibers, which can be critical when trying to selectively remove CO2 from a valuable gas such as biogas. This study evaluated fiber performance under conditions that mimic these effects by analyzing the carbon transfer efficiency (CTE), CO2 flux (JCO2), and outlet CO2 concentration compared to baseline values. Wetting of the interior fiber macropores resulted in an average 32% ± 8.3% decrease in flux, which was greater than for flooding of the outer macropores, which showed no significant change. All tests resulted in a decrease in CTE and an increase in outlet CO2. The presence of elevated O2 levels did not decrease the CO2 flux compared to baseline values, but it increased the O2 concentration and decreased the CH4 concentration at the distal end of the fibers. These findings highlight that liquid accumulation can decrease HFM performance during MC for microalgal cultivation, while the presence of supersaturated O2 can reduce separation efficiency.

I performed Franz Liszt's Hungarian Rhapsody No. 2 and orally presented the findings of my written literature review. I addressed the relationship between the brain and muscles, and how complex neural networks develop in pianists. I focused on how proprioception, manual dexterity, somatosensory motor integration and fine motor function related to the technical aspects of my piano performance.

Objective: This study explored the relationship between patient satisfaction, health literacy, experiences with discrimination and insurance status for African American emerging adults between the ages of 18 and 29. Methods: Participants (N=148, 68.2% female, mean age 22) were recruited from African American/Black college organizations and completed an online survey. Results: The results indicated a strong positive relationship between patient satisfaction and health literacy and a strong negative relationship between patient satisfaction and experiences with discrimination. The results also indicated significant difference in patient satisfaction between those with and without insurance. Those with insurance reported higher patient satisfaction compared to those without.

Early detection of disease is essential for alleviating disease burden, increasing success rate and decreasing mortality rate especially for cancer. To improve disease diagnostics, many candidate biomarkers have been suggested using molecular biology or image analysis techniques over the past decade. The receiver operating characteristics (ROC) curve is a standard technique to evaluate a diagnostic accuracy of biomarkers, but it has some limitations especially for heterogeneous diseases. As an alternative of the ROC curve analysis, we suggest a jittered dot plot (JDP) and JDP-based evaluation measures, above mean difference (AMD) and averaged above mean difference (AAMD). We demonstrate how JDP and AMD or AAMD together better evaluate biomarkers than the standard ROC curve. We analyze real and heterogeneous basal-like breast cancer data.

Obesity has reached epidemic proportions all around the world, and it has doubled in prevalence in both adults and children in over 70 countries from 1980 to 2015 (Afshin et al., 2017). Excessive weight gain in this proportion has been shown to negatively affect human cognition, reward neurocircuitry, stress responsiveness, and quality of life (Morris et al., 2015). Obesity is an example of a complex interaction between the environment (i.e., high fat diets) and heredity (i.e., polygenic patterns of inheritance). The overconsumption of a high-fat diet (HFD) is an environmental factor that commonly induces weight gain (Hariri & Thibault, 2010). Two dietary-induced phenotypes have been observed in rats as a bimodal distribution of weight gain: obesity-prone (OP) and obesity-resistant (OR). Levin et al. (1997) investigated male and female HFD-fed Sprague-Dawley rats designated as OR when their weight gains were less than the heaviest chow-fed controls, and OP when their weight gains were greater than the heaviest chow-fed controls. OP rats showed greater weight gain, similar energy intake (EI), and similar feed efficiency (FE) compared to OR rats. Pagliassotti et al. (1997) designated male HFD-fed Wistar rats as OP and OR based on upper and lower tertiles of weight gain. OP rats displayed greater weight gain and EI than OR rats. These investigations highlight a predicament regarding rodent research in obesity: independent variables such as rat age, gender, strain, distribution of dietary macronutrients, and fatty acid composition of HFD and chow vary considerably, making it challenging to generalize data. Our experiment utilized outbred male Sprague-Dawley rats (5-6 weeks) administered a chow diet (19% energy from fat; 3.1 kcal/g) and a lard-based HFD (60% energy from fat; 5.24 kcal/g) over eight weeks. Separate rat populations were examined over three consecutive years (2017-2020), and independent obesogenic environmental variables were controlled. We investigated the persistence of weight gain, EI, and FE in HFD-fed rats inclusive of a population of designated OP and OR rats based on tertiles of weight gain. We define persistence as being p > 0.05. We hypothesize that the profiles (periodic data) of the dependent variables (weight gain, EI, FE) will be similar and persistent throughout the three separate years, but the magnitudes (cumulative data) of the dependent variables will differ. Our findings demonstrate that HFD, OP, and OR groups were persistent for periodic and cumulative weight gain, along with FE across the three consecutive independent years. Our findings also demonstrate impersistence for periodic EI in all groups, along with impersistence in cumulative EI for CHOW, OP, and OR groups. Therefore, our results allude to an inconsistent relationship between EI and weight gain, indicating that EI does not completely explain weight gain. Thus, the weakness between EI and weight gain relationship may be attributed to a polygenic pattern of inheritance, possibly signaling a weight setpoint regardless of EI.

For our thesis, we analyzed a set of data from the on-going longitudinal study, “Aging In the Time of COVID-19” (Guest et al., ongoing) from the Center for Innovation in Healthy and Resilient Aging at Arizona State University. This study researched how COVID-19 and the resulting physical/social distancing impacted aging individuals' health, wellbeing, and quality-of-life. The survey collected data regarding over 1400 participants’ social connections, health, and experiences during COVID-19. This study gathered information about participants’ comorbid conditions, age, sex, location, etc. We presented this work in the form of a website including the traditional elements of an Honors Thesis as well as a visual essay with the data analysis portion coded with the JavaScript library D3 and a list of resources for our target audience, older adults who are experiencing social isolation and/or loneliness.

In Photosystem II of plants, the proton motive force that is essential for life is generated partly by the water oxidation process where the tyrosine and histidine 190 (hydrogen bonded) amino acids play an important role. The proton-coupled electron transfer (PCET) process involving these two molecules has been replicated using a benzimidazole-phenol (BIP) construct as an artificial model of both the intramolecular hydrogen bond interaction and the associated PCET process. BIP is a nearly planar molecule and features a strong intramolecular hydrogen bond between the phenol and the nitrogen of the benzimidazole. When the molecule is oxidized electrochemically, the phenolic proton is transferred to the nitrogen of the benzimidazole moiety in a PCET mechanism. Herein the design, synthesis, and physicochemical characterization of a new BIP derivative is described. By introducing a methyl group in the new design, we intentionally increase the dihedral angle between the benzimidazole and phenol rings. The presence of the methyl group affects the ground-state PCET and the excited-state intramolecular proton transfer processes as well. The break in the coplanarity weakens the strength of the intramolecular hydrogen bond, decreases the chemical reversibility, and quenches the emission from the excited-state intramolecular proton transfer state. The findings contribute to understanding the importance of having a nearly planar structure in bioinspired artificial photosynthetic systems.