Matching Items (1,000)
Description
The purpose of this dissertation is to study not only relations between Latin America and the United States, but also Latin American states with each other. It specifically aims to examine the extent to which the United States, the principal hegemonic power in the Americas, can play a constructive role by providing regional public goods. These goods include conflict resolution and economic progress. Although the United States has the potential to create such goods, it also has the potential to create public bads in the form of regional instability, political terror, and economic stagnation. This raises two fundamental research questions: Under what conditions can Washington play a positive role and if these conditions cannot be met, under what conditions can Latin American nations bypass the United States and create their own economic progress and conflict resolution strategies? Drawing upon qualitative research methods and case studies that have attracted scant academic attention, this dissertation finds that through regional multilateral diplomatic negotiations, the United States can play a positive role. However, due to U.S. parochial economic interests and the marginalization of diplomacy as a foreign policy tool, these conditions rarely occur. This research further finds, however, that through flexible regionalization Latin American nations can bypass the United States and create their own goods. Supported by an alternative regional power, flexible regionalization relies upon supranational institutions that exclude the United States, emphasize permanent political and economic integration, and avoid inflexible monetary unions. Through this type of regionalization, Latin America can decrease U.S. interference, sustain political and economic autonomy, and open space for alternative conflict resolution strategies and economic policies that Washington would otherwise oppose. This dissertation is academically significant and policy relevant. First, it reconsiders diplomacy as an instrumental variable for peace and offers generalizable results that can be applied to additional cases. Moreover, finding that Latin American countries can address their own regional issues, this study recognizes the positive agency of Latin America and counters the negative essentialization commonly found in U.S. academic and policy research. Finally, this research offers policy advice for both the United States and Latin America.
ContributorsRipley, Charles (Author) / Doty, Roxanne L (Thesis advisor) / Stoner, Lynn (Committee member) / Simon, Sheldon (Committee member) / Arizona State University (Publisher)
Created2013
Description
The brain is a fundamental target of the stress response that promotes adaptation and survival but the repeated activation of the stress response has the potential alter cognition, emotion, and motivation, key functions of the limbic system. Three structures of the limbic system in particular, the hippocampus, medial prefrontal cortex (mPFC), and amygdala, are of special interest due to documented structural changes and their implication in post-traumatic stress disorder (PTSD). One of many notable chronic stress-induced changes include dendritic arbor restructuring, which reflect plasticity patterns in parallel with the direction of alterations observed in functional imaging studies in PTSD patients. For instance, chronic stress produces dendritic retraction in the hippocampus and mPFC, but dendritic hypertrophy in the amygdala, consistent with functional imaging in patients with PTSD. Some have hypothesized that these limbic region's modifications contribute to one's susceptibility to develop PTSD following a traumatic event. Consequently, we used a familiar chronic stress procedure in a rat model to create a vulnerable brain that might develop traits consistent with PTSD when presented with a challenge. In adult male rats, chronic stress by wire mesh restraint (6h/d/21d) was followed by a variety of behavioral tasks including radial arm water maze (RAWM), fear conditioning and extinction, and fear memory reconsolidation to determine chronic stress effects on behaviors mediated by these limbic structures. In chapter 2, we corroborated past findings that chronic stress caused hippocampal CA3 dendritic retraction. Importantly, we present new findings that CA3 dendritic retraction corresponded with poor spatial memory in the RAWM and that these outcomes reversed after a recovery period. In chapter 3, we also showed that chronic stress impaired mPFC-mediated extinction memory, findings that others have reported. Using carefully assessed behavior, we present new findings that chronic stress impacted nonassociative fear by enhancing contextual fear during extinction that generalized to a new context. Moreover, the generalization behavior corresponded with enhanced functional activation in the hippocampus and amygdala during fear extinction memory retrieval. In chapter 5, we showed for the first time that chronic stress enhanced amygdala functional activation during fear memory retrieval, i.e., reactivation. Moreover, these enhanced fear memories were resistant to protein synthesis interference to disrupt a previously formed memory, called reconsolidation in a novel attempt to weaken chronic stress enhanced traumatic memory. Collectively, these studies demonstrated the plastic and dynamic effects of chronic stress on limbic neurocircuitry implicated in PTSD. We showed that chronic stress created a structural and functional imbalance across the hippocampus, mPFC, and amygdala, which lead to a PTSD-like phenotype with persistent and exaggerated fear following fear conditioning. These behavioral disruptions in conjunction with morphological and functional imaging data reflect a chronic stress-induced imbalance between hippocampal and mPFC regulation in favor of amygdala function overdrive, and supports a novel approach for traumatic memory processing in PTSD.
ContributorsHoffman, Ann (Author) / Conrad, Cheryl D. (Thesis advisor) / Olive, M. Foster (Committee member) / Hammer, Jr., Ronald P. (Committee member) / Sanabria, Federico (Committee member) / Arizona State University (Publisher)
Created2013
Description
Chronic restraint stress impairs hippocampal-mediated spatial learning and memory, which improves following a post-stress recovery period. Here, we investigated whether brain derived neurotrophic factor (BDNF), a protein important for hippocampal function, would alter the recovery from chronic stress-induced spatial memory deficits. Adult male Sprague-Dawley rats were infused into the hippocampus with adeno- associated viral vectors containing the coding sequence for short interfering (si)RNA directed against BDNF or a scrambled sequence (Scr), with both containing the coding information for green fluorescent protein to aid in anatomical localization. Rats were then chronically restrained (wire mesh, 6h/d/21d) and assessed for spatial learning and memory using a radial arm water maze (RAWM) either immediately after stressor cessation (Str-Imm) or following a 21-day post-stress recovery period (Str-Rec). All groups learned the RAWM task similarly, but differed on the memory retention trial. Rats in the Str-Imm group, regardless of viral vector contents, committed more errors in the spatial reference memory domain than did non-stressed controls. Importantly, the typical improvement in spatial memory following recovery from chronic stress was blocked with the siRNA against BDNF, as Str-Rec-siRNA performed worse on the RAWM compared to the non-stressed controls or Str-Rec-Scr. These effects were specific for the reference memory domain as repeated entry errors that reflect spatial working memory were unaffected by stress condition or viral vector contents. These results demonstrate that hippocampal BDNF is necessary for the recovery from stress-induced hippocampal dependent spatial memory deficits in the reference memory domain.
ContributorsOrtiz, J. Bryce (Author) / Conrad, Cheryl D. (Thesis advisor) / Olive, M. Foster (Committee member) / Taylor, Sara (Committee member) / Bimonte-Nelson, Heather A. (Committee member) / Arizona State University (Publisher)
Created2013
Description
Amidst studies attempting to fix the U.S., China, and their relationship into preconceived frameworks of international relations, presupposed definitions, and models of reality, this dissertation adopts an identity centric approach to understanding the nature of U.S.-China relations and, more generally, international politics. This approach involves utilizing an interpretive method to understanding, analyzing the narratives of self and other expressed by political actors and how their identities--expressed through narratives--interact with one another and thus how they influence or reflect social behavior. Striving for greater understanding and a more intellectually honest approach to the study of international politics, this study seeks not theory building or generalizability in a traditional "scientific" sense. Rather, informed by thinkers from Karl Popper through those more recent, this dissertation develops and outlines an in-depth, contextual approach to understanding, applying this approach to analyzing the nature of U.S.-China relations. Ultimately, this study argues that U.S. and Chinese identities and how their identities interact influence the nature of U.S.-China relations, whether the relationship tends towards cooperation or conflict, and that in order to glimpse this nature researchers must delve into the details of their subjects of study. Attempting to do so, this study analyzes U.S.-China relations surrounding the terrorist attacks of 11 September 2001, relations regarding the Diaoyu/Senkaku Islands dispute between China and Japan as it pertains to U.S. relations with China, and relations regarding encounters between the U.S. and China in cyber space (paying special note to attempts to define this "space" itself).
ContributorsKoehler, Clifford Eugene (Author) / Simon, Sheldon (Thesis advisor) / Doty, Roxanne (Committee member) / Ashley, Richard (Committee member) / Arizona State University (Publisher)
Created2014
Description
East Asia in the aftermath of the Cold War might provide the most favorable case for realist theory due to historical rivalries, territorial disputes, economic competition, great power politics and deep-rooted realist beliefs among politicians in the region. Yet the fundamental realist prediction of balance of power in the region has not materialized. Neither internal nor external balancing in their original senses is explicitly present. This poses a serious challenge to realism and more broadly, western international relations theories for understanding regional dynamics. Several explanations have been put forward in previous research, such as a total rejection of the applicability of realism for explaining East Asian politics, modifying realism by adding new variables, and focusing on domestic variables. Using a neoclassical realist term, underbalancing, this dissertation goes beyond neoclassical realist theory of underbalancing by reintroducing the distinction between external and internal balancing, which has direct implications for the resources needed for a balancing policy and external reactions to balancing policy. In particular, this approach emphasizes the effect of interaction between states on underbalancing. By doing so, it also highlights what is omitted by realism, namely, the agency of the targeted state at risk of being balanced. In other words, the policy of the state that is aware of its risk of being balanced could draw upon foreign policy tools it possesses to neutralize the balancing efforts from others. This notion of state policies influencing the outcome of balance of power is tested with post-Cold War East Asian politics. The cases included China-Japan and China-ASEAN strategic interactions after the Cold War. Based on materials from public media outlets, official documents and recently leaked U.S. diplomatic cables, this dissertation argues that China's policies towards neighboring states- policies expressed variously through cultural, diplomatic, economic and security initiatives- are indispensable to explain the fact of underbalancing in the region.
ContributorsChi, Zhipei (Author) / Simon, Sheldon (Thesis advisor) / Rush, James (Committee member) / Shair-Rosenfield, Sarah (Committee member) / Arizona State University (Publisher)
Created2014
Description
Counterinsurgency (COIN) is a long process that even great powers struggle with. Nevertheless, South Korea as a middle power was successful with COINs in Vietnam and Iraq. What were the drivers for the Republic of Korea (ROK) military's success? This dissertation maintains that the unusual nature of missions coupled with political/socio-cultural advantages are sufficient conditions for success of the middle power COIN. COIN missions are seen as unusual to middle powers. A rare mission stimulates military forces to fight harder because they recognize this mission as an opportunity to increase their national prestige. COIN mission success is also more probable for middle powers because their forces make the best of their country's political/socio-cultural advantages. The ROK military's COINs are optimal cases to test these hypotheses. The ROK military's COIN in Vietnam was an extremely rare mission, which increased its enthusiasm. This enthusiasm was converted into appropriate capabilities. By identifying battleground dynamics, the ROK forces initially chose an enemy-oriented approach based upon the method of company-led tactical base, and then later introduced a population-led method. South Korea's political/socio-cultural advantages also contributed to its military success in Vietnam. The Confucius culture that South Koreans and Vietnamese shared allowed the ROK forces to win the hearts and minds of the Vietnamese population. The mission in Iraq was also a rare and important one for national prestige. Accordingly, South Korean forces were equipped with pride and were enthusiastic about missions in Arbil. They changed their organization from a rigid one to a more flexible one by strengthening civil-military units. The ROK military possessed the ability to choose a population-centric approach. South Korea's political and cultural climate also served as an advantage to accomplish COIN in Iraq. The culture of Jung allowed ROK soldiers to sincerely help the local Iraqis. This project contributes to developing a theory of the middle power COIN. The findings also generate security policy implications of how to deal with contingent situations led by the collapse of the North Korean regime and how to redefine the ROK military strategy for the future.
ContributorsBan, Kil-Joo (Author) / Simon, Sheldon (Thesis advisor) / Gortzak, Yoav (Committee member) / Mackinnon, Stephen (Committee member) / Arizona State University (Publisher)
Created2011
Description
Females are highly vulnerable to the effects of methamphetamine, and understanding the mechanisms of this is critical to addressing methamphetamine use as a public health issue. Hormones may play a role in methamphetamine sensitivity; thus, the fluctuation of various endogenous peptides during the postpartum experience is of interest. This honors thesis project explored the relation between anxiety-like behavior, as measured by activity in an open field, and conditioned place preference to methamphetamine in female versus male rats. The behavior of postpartum as well as virgin female rats was compared to that of male rats. There was not a significant difference between males and females in conditioned place preference to methamphetamine, yet females showed higher locomotor activity in response to the drug as well as increased anxiety-like behavior in open field testing as compared to males. Further study is vital to comprehending the complex mechanisms of sex differences in methamphetamine addiction.
ContributorsBaker, Allison Nicole (Author) / Olive, M. Foster (Thesis director) / Presson, Clark (Committee member) / Hansen, Whitney (Committee member) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
The purpose of this research is to identify the factors contributing the resiliency of Syria's President Assad amongst a backdrop of falling authoritarians during the Arab Spring. After determining the Assad's regime's strategies of authoritarian rule both before and after the 2011 uprisings, this paper theorizes what Assad's persistence is most dependent on today by analyzing his discourse throughout the conflict. Assad's framing of the war to the media has significantly legitimized his rule.
ContributorsKassab, Seema (Author) / Parmentier, Mary Jane (Thesis director) / Simon, Sheldon (Committee member) / Barrett, The Honors College (Contributor) / Department of Economics (Contributor) / W. P. Carey School of Business (Contributor) / School of Politics and Global Studies (Contributor) / Sandra Day O'Connor College of Law (Contributor)
Created2015-05
Description
An introduction to neuroscientific thought aimed at an audience that is not educated in biology. Meant to be readable and easily understood by anyone with a high school education. The first section is completed in its entirety, with outlines for the proposed final sections to be completed over the next few years.
ContributorsNelson, Nicholas Alan (Author) / Olive, M. Foster (Thesis director) / Brewer, Gene (Committee member) / Barrett, The Honors College (Contributor) / Department of Psychology (Contributor) / School of Life Sciences (Contributor) / School of Historical, Philosophical and Religious Studies (Contributor)
Created2014-05
Description
The unprecedented rise of terrorist network ISIL has brought the revolutionary Salafi agenda to the forefront of global politics. This thesis provides an analysis of the ideology and an overview of ISIL. The research is comprised of reports on the organization from prominent think-tanks, books analyzing the tenets and thinkers of Salafi radicalism and original source material confiscated from ISIL's predecessor al-Qaeda in Iraq (AQI). An international coalition is posited as a solution to the threat as well as the Middle Eastern terrorist threat more broadly. However, the likelihood of such international cooperation is minimal, and the commitment it would require may make it unfeasible.
ContributorsSims, Alyssa Gabrielle (Author) / Simon, Sheldon (Thesis director) / Ripley, Charles (Committee member) / Barrett, The Honors College (Contributor) / School of International Letters and Cultures (Contributor) / W. P. Carey School of Business (Contributor) / School of Historical, Philosophical and Religious Studies (Contributor)
Created2015-05