Among other functions, the Notch signaling pathway contributes to the development of somites in animals. It involves a cell signaling mechanism with a wide range of functions, including cellular differentiation, and the formation of the embryonic structures (embryogenesis). All multicellular animals use Notch signaling, which is involved in the development, maintenance, and regeneration of a range of tissues. The Notch signaling pathways spans two cells, and consists of receptor proteins, which cross one cell's membrane and interacts with proteins on adjacent cells, called ligands. The physical interaction of receptors and ligands directs the genetic response of the first cell to produce proteins that define the type of cell it will become. One of the earliest discovered roles of the Notch signaling pathway in vertebrates is in somite formation (somitogenesis). Somitogenesis is the formation of somites, which are sphere-like structures in early vertebrate embryos that are the first visible signs of segmentation. Somites then help to define many tissues and features of the adult animal's body. The Notch signaling pathway plays at least two distinct roles during somitogenesis: the first is maintenance of an oscillating protein gradient, called the segmental clock, and the second is establishing the polarity of somites. Mutations to genes in the Notch pathway can result in birth defects characterized by abnormal development of bones of the spine and ribs, like spondylocostal dysostosis. Additionally, dysfunction in the pathway linked to cancer progression, HIV-related complications, and Alzheimer´s disease, among other disorders.

James M Cummins published 'The Role of Maternal Mitochondria during Oogenesis, Fertilization and Embryogenesis' 30 January 2002 in Reproductive BioMedicine Online. In the article, Cummins examines the role of the energy producing cytoplasmic particles, or organelles called mitochondria. Humans inherit mitochondria from their mothers, and mechanisms have evolved to eliminate sperm mitochondria in early embryonic development. Mitochondria contain their own DNA (mtDNA) separate from nuclear DNA (nDNA). Cummins's article describes how mitochondria influence the development of egg cells called oocytes. Mitochondria also function in the union of oocyte and sperm, early formation of the embryo, and in in vitro fertilization (IVF) techniques, such as the transfer of donor cytoplasm into an oocyte resulting in a technique called ooplasmic transfer.

In 2005, the organization Asian Communities for Reproductive Justice, or ACRJ, published “A New Vision for Advancing Our Movement for Reproductive Health, Reproductive Rights, and Reproductive Justice,” hereafter “A New Vision,” in which the authors explain how reproductive justice is hindered by societal oppressions against women of color. ACRJ, known as Forward Together since 2012, was a founding member of SisterSong Women of Color Reproductive Justice Collective, a collective of organizations founded by people of color that work to advance the reproductive justice movement. In “A New Vision,” the authors elaborate that reproductive justice is about changing the societal structures that produce reproductive oppressions. They assert that a radical transformation is necessary in order to progress toward the establishment of full and equal human rights, reproductive rights, and economic rights to ensure equitable access to healthcare, education, and opportunity.

Resilient infrastructure research has produced a myriad of conflicting definitions and analytic frameworks, highlighting the difficulty of creating a foundational theory that informs disciplines as diverse as business, engineering, ecology, and disaster risk reduction. Nevertheless, there is growing agreement that resilience is a desirable property for infrastructure systems – i.e., that more resilience is always better. Unfortunately, this view ignore that the fact that a single concept of resilience is insufficient to ensure effective performance under diverse and volatile stresses. Scholarship in resilience engineering has identified at least four irreducible resilience concepts, including: rebound, robustness, graceful extensibility, and sustained adaptability.

In this paper, we clarify the meaning of the word resilience and its use, explain the advantages of the pluralistic approach to advancing resilience theory, and clarify two of the four conceptual understandings: robustness and graceful extensibility. Furthermore, we draw upon examples in electric power, transportation, and water systems that illustrate positive and negative cases of resilience in infrastructure management and crisis response. The following conclusions result:

1. Robustness and graceful extensibility are different strategies for resilience that draw upon different system characteristics.
2. Neither robustness nor extensibility can prevent all hazards.
3. While systems can perform both strategies simultaneously, their drawbacks are different.

Robust infrastructure systems fail when policies and procedures become stale, or when faced with overwhelming surprise. Extensible systems fail when a lack of coordination or exhaustion of resources results from decompensation. Consequently, resilience is found neither only in robustness, nor only in extensibility, but in the capacity apply both and switch between them at will.