Matching Items (43)
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Description
Serial femtosecond crystallography (SFX) using X-ray free-electron laser sources is an emerging method with considerable potential for time-resolved pump-probe experiments. Here we present a lipidic cubic phase SFX structure of the light-driven proton pump bacteriorhodopsin (bR) to 2.3 Å resolution and a method to investigate protein dynamics with modest sample requirement.

Serial femtosecond crystallography (SFX) using X-ray free-electron laser sources is an emerging method with considerable potential for time-resolved pump-probe experiments. Here we present a lipidic cubic phase SFX structure of the light-driven proton pump bacteriorhodopsin (bR) to 2.3 Å resolution and a method to investigate protein dynamics with modest sample requirement. Time-resolved SFX (TR-SFX) with a pump-probe delay of 1 ms yields difference Fourier maps compatible with the dark to M state transition of bR. Importantly, the method is very sample efficient and reduces sample consumption to about 1 mg per collected time point. Accumulation of M intermediate within the crystal lattice is confirmed by time-resolved visible absorption spectroscopy. This study provides an important step towards characterizing the complete photocycle dynamics of retinal proteins and demonstrates the feasibility of a sample efficient viscous medium jet for TR-SFX.
ContributorsNogly, Przemyslaw (Author) / Panneels, Valerie (Author) / Nelson, Garrett (Author) / Gati, Cornelius (Author) / Kimura, Tetsunari (Author) / Milne, Christopher (Author) / Milathianaki, Despina (Author) / Kubo, Minoru (Author) / Wu, Wenting (Author) / Conrad, Chelsie (Author) / Coe, Jesse (Author) / Bean, Richard (Author) / Zhao, Yun (Author) / Bath, Petra (Author) / Dods, Robert (Author) / Harimoorthy, Rajiv (Author) / Beyerlein, Kenneth R. (Author) / Rheinberger, Jan (Author) / James, Daniel (Author) / Deponte, Daniel (Author) / Li, Chufeng (Author) / Sala, Leonardo (Author) / Williams, Garth J. (Author) / Hunter, Mark S. (Author) / Koglin, Jason E. (Author) / Berntsen, Peter (Author) / Nango, Eriko (Author) / Iwata, So (Author) / Chapman, Henry N. (Author) / Fromme, Petra (Author) / Frank, Matthias (Author) / Abela, Rafael (Author) / Boutet, Sebastien (Author) / Barty, Anton (Author) / White, Thomas A. (Author) / Weierstall, Uwe (Author) / Spence, John (Author) / Neutze, Richard (Author) / Schertler, Gebhard (Author) / Standfuss, Jorg (Author) / College of Liberal Arts and Sciences (Contributor) / Department of Physics (Contributor) / Department of Chemistry and Biochemistry (Contributor) / Biodesign Institute (Contributor) / Applied Structural Discovery (Contributor) / School of Molecular Sciences (Contributor)
Created2016-08-22
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Description
This paper documents a study of the relationship between heads up display (HUDs) customization and player performance. Additional measures capture satisfaction and prior gaming experience. The goal of this study was to develop a framework on which future Human Systems Engineering studies could create games that are tailor made to

This paper documents a study of the relationship between heads up display (HUDs) customization and player performance. Additional measures capture satisfaction and prior gaming experience. The goal of this study was to develop a framework on which future Human Systems Engineering studies could create games that are tailor made to examine a given area of interest. This study utilized a two-by-two design, where participants play a two-dimensional (2D) platformer game with a mechanic that incentivizes attention to the HUD. This study successfully developed a framework and was moderately successful in uncovering limitations and demonstrating areas for improvement in follow-on studies. Specifically, this study illuminated issues with the low amount of usable data caused by design issues, participant apathy, and reliance on self-reporting data collection. Extensions of this study can utilize this framework and should look to recruit beyond crowdsourcing platforms, collect more diverse data, reduce participant effort, and address other considerations that were found during execution.
ContributorsWallace, Xavier Guillermo (Author) / Roscoe, Rod (Thesis advisor) / Mara, Andrew (Committee member) / Cooke, Nancy (Committee member) / Arizona State University (Publisher)
Created2022
Description

"A Stitch in Time" is a creative project that centered around a creative writing project. The story explores the experiences of a witch named Elio who helps people solve issues in their real lives through the power of dreams. However, he must come to terms with the issues that are

"A Stitch in Time" is a creative project that centered around a creative writing project. The story explores the experiences of a witch named Elio who helps people solve issues in their real lives through the power of dreams. However, he must come to terms with the issues that are present in his own past -- and continue to affect him in the present -- in order to fully reach his potential as a witch. The completed version of this thesis project was two written chapters and a full detailed outline.

ContributorsSaifi, Abigail (Author) / LaCroix, Kristin (Thesis director) / Mara, Andrew (Committee member) / Barrett, The Honors College (Contributor) / Department of English (Contributor) / Department of Psychology (Contributor)
Created2023-05
Description

The New Jersey Childhood Obesity Study, funded by the Robert Wood Johnson Foundation, aims to provide vital information for planning, implementing and evaluating interventions aimed at preventing childhood obesity in five ew Jersey municipalities: Camden, Newark, New Brunswick, Trenton, and Vineland. These five communities are being supported by RWJF's New

The New Jersey Childhood Obesity Study, funded by the Robert Wood Johnson Foundation, aims to provide vital information for planning, implementing and evaluating interventions aimed at preventing childhood obesity in five ew Jersey municipalities: Camden, Newark, New Brunswick, Trenton, and Vineland. These five communities are being supported by RWJF's New Jersey Partnership for Healthy Kids program to plan and implement policy and environmental change strategies to prevent childhood obesity.

Effective interventions for addressing childhood obesity require community specific information on who is most at risk and on contributing factors that can be addressed through tailored interventions that meet the needs of the community.

Using a comprehensive research study, the Center for State Health Policy at Rutgers University is working collaboratively with the State Program Office for New Jersey Partnership for Healthy Kids and the five communities to address these information needs. The main components of the study include:

• A household survey of 1700 families with 3 -18 year old children

• De-identified heights and weights data from public school districts

• Assessment of the food and physical activity environments using objective data

Data books and maps based on the results of the study are being shared with the community coalitions in the five communities to help them plan their interventions.

Created2010
Description

The New Jersey Childhood Obesity Study, funded by the Robert Wood Johnson Foundation, aims to provide vital information for planning, implementing and evaluating interventions aimed at preventing childhood obesity in five New Jersey municipalities: Camden, Newark, New Brunswick, Trenton, and Vineland.

These five communities are being supported by RWJF's New Jersey

The New Jersey Childhood Obesity Study, funded by the Robert Wood Johnson Foundation, aims to provide vital information for planning, implementing and evaluating interventions aimed at preventing childhood obesity in five New Jersey municipalities: Camden, Newark, New Brunswick, Trenton, and Vineland.

These five communities are being supported by RWJF's New Jersey Partnership for Healthy Kids program to plan and implement policy and environmental change strategies to prevent childhood obesity.

Effective interventions for addressing childhood obesity require community-specific information on who is most at risk and on contributing factors that can be addressed through tailored interventions that meet the needs of the community.

Using a comprehensive research study, the Center for State Health Policy at Rutgers University is working collaboratively with the State Program Office for New Jersey Partnership for Healthy I<ids and the five communities to address these information needs. The main components of the study include:

• A household survey of 1700 families with 3 -18 year old children

• De-identified heights and weights data from public school districts

• Assessment of the food and physical activity environments using objective data

Data books and maps based on the results of the study are being shared with the community coalitions in the five communities to help them plan their interventions.

Created2010
Description

The New Jersey Childhood Obesity Study, funded by the Robert Wood Johnson Foundation, aims to provide vital information for planning, implementing and evaluating interventions aimed at preventing childhood obesity in five New Jersey municipalities: Camden, Newark, New Brunswick, Trenton, and Vineland. These five communities are being supported by RWJF's New

The New Jersey Childhood Obesity Study, funded by the Robert Wood Johnson Foundation, aims to provide vital information for planning, implementing and evaluating interventions aimed at preventing childhood obesity in five New Jersey municipalities: Camden, Newark, New Brunswick, Trenton, and Vineland. These five communities are being supported by RWJF's New Jersey Partnership for Healthy Kids program to plan and implement policy and environmental change strategies to prevent childhood obesity.

Effective interventions for addressing childhood obesity require community specific information on who is most at risk and on contributing factors that can be addressed through tailored interventions that meet the needs of the community.

Using a comprehensive research study, the Center for State Health Policy at Rutgers University is working collaboratively with the State Program Office for New Jersey Partnership for Healthy Kids and the five communities to address these information needs. The main components of the study include:

A household survey of 1700 families with 3 -18 year old children

De-identified heights and weights data from public school districts

Assessment of the food and physical activity environments using objective data

Data books and maps based on the results of the study are being shared with the community coalitions in the five communities to help them plan their interventions.

Created2010
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Description
Contracting is an integral component of both government (i.e., public) and private business. As part of the contracting process, contracting companies must submit proposals to federal agencies or private businesses; individuals who write proposals on behalf of contracting companies are known as proposal writers. Although proposal writers are central to

Contracting is an integral component of both government (i.e., public) and private business. As part of the contracting process, contracting companies must submit proposals to federal agencies or private businesses; individuals who write proposals on behalf of contracting companies are known as proposal writers. Although proposal writers are central to the proposal writing process, they are only marginally represented in available literature on the contracting and proposal writing processes. Additionally, available literature is disproportionately influenced by industry and trade sources, versus academic sources, and completed by industry authorities. As a result, key findings from such reports may not reflect the feedback gathered as part of this research. This research utilized a 25-question survey with both multiple choice and free answer questions to gauge the most and least effective components of the proposal writing process. Communication and collaboration—internally within the proposal team or within the company, and externally between the company and customers, clients, etc.— were cited as both the most and least effective components of the process. Notably, however, communication and collaboration were not the most frequently encountered issues, as only 23.5% of proposal writers reported communication as a common issues. Instead, supporting resources (46.9%), time/ schedule (49.2%), and direction. instructions (44.9%) were reported as the most common issues that proposal writers encountered, although one in four participants noted that issues were not consistent across proposals.
ContributorsRast, Mickella (Author) / Mara, Andrew (Thesis advisor) / Stambler, Mollie (Committee member) / Madson, Michael (Committee member) / Lambrecht, Kathryn (Committee member) / Arizona State University (Publisher)
Created2023
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Description
Educational videos are a large part of the YouTube community, and an emerging niche of these videos is educational videos created by professionals in the field. Creating content on their profession establishes them as experts and trustworthy sources of information that audiences can turn to while researching topics relating to

Educational videos are a large part of the YouTube community, and an emerging niche of these videos is educational videos created by professionals in the field. Creating content on their profession establishes them as experts and trustworthy sources of information that audiences can turn to while researching topics relating to the field. This study includes eighteen videos from three doctors creating medical-educational content posted to YouTube. The purpose of this study was to determine if these content creators use best practices for educational videos and the common themes these videos share. The best practices were gathered from previous research conducted on educational videos. These practices are viewability, timing, accessibility, reliability, and confidence. Commonalities noted across channels were then coded to find common themes within the niche. These themes do not need to be in every video, but they should be present on two channels. These themes include formatting videos and thumbnails, styles of videos, and their use of humor and entertaining additional content. These videos also break down the negative perceptions of authority that are often attached to doctors by humanizing the doctors to the audience. Combining these best practices and the use of the found common themes strengthen the videos to create engaging and educational content.
ContributorsTaylor, Darby Lyn (Author) / Mara, Andrew (Thesis advisor) / Carradini, Stephen (Committee member) / Madson, Michael (Committee member) / Arizona State University (Publisher)
Created2022
Description
The field of technical communication studies informational documents, such as instruction manuals or research articles and so on. Games have instructions, or rules, which must be documented. Technical communication scholars have studied documents for video games, but similar research on tabletop rulebook documents appears to be mostly absent, an absence

The field of technical communication studies informational documents, such as instruction manuals or research articles and so on. Games have instructions, or rules, which must be documented. Technical communication scholars have studied documents for video games, but similar research on tabletop rulebook documents appears to be mostly absent, an absence that creates a gap within technical communication research. Filling this gap, my work studies tabletop game rulebooks, which lie within the genre of instruction manuals. Technical communication has produced a theory of effective manual design, and I present much of that theory as, what I call, standards of effective manual design. I observed 30 tabletop game rulebooks to see how well they follow those standards, and I interviewed or surveyed people who played 15 of those games to see how effective the games’ rulebooks are for those people. This allowed me to see how well a rulebook’s adherence to the standards of effective manual design aligned with its effectiveness. This alignment did not always hold; consequently, though an effective rulebook follows the standards of effective manual design, a rulebook can follow said standards yet be ineffective. I conclude that following the standards is only a necessary, not sufficient, condition for making an effective rulebook. The standards must also be used in the correct way and amount.
ContributorsRiggleman, Mark Kenneth (Author) / Lambrecht, Kathryn (Thesis advisor) / Cooke, Lynne (Committee member) / Mara, Andrew (Committee member) / Arizona State University (Publisher)
Created2024