Matching Items (50)
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Description
Serial femtosecond crystallography (SFX) has opened a new era in crystallo­graphy by permitting nearly damage-free, room-temperature structure determination of challenging proteins such as membrane proteins. In SFX, femtosecond X-ray free-electron laser pulses produce diffraction snapshots from nanocrystals and microcrystals delivered in a liquid jet, which leads to high protein consumption.

Serial femtosecond crystallography (SFX) has opened a new era in crystallo­graphy by permitting nearly damage-free, room-temperature structure determination of challenging proteins such as membrane proteins. In SFX, femtosecond X-ray free-electron laser pulses produce diffraction snapshots from nanocrystals and microcrystals delivered in a liquid jet, which leads to high protein consumption. A slow-moving stream of agarose has been developed as a new crystal delivery medium for SFX. It has low background scattering, is compatible with both soluble and membrane proteins, and can deliver the protein crystals at a wide range of temperatures down to 4°C. Using this crystal-laden agarose stream, the structure of a multi-subunit complex, phycocyanin, was solved to 2.5 Å resolution using 300 µg of microcrystals embedded into the agarose medium post-crystallization. The agarose delivery method reduces protein consumption by at least 100-fold and has the potential to be used for a diverse population of proteins, including membrane protein complexes.
ContributorsConrad, Chelsie (Author) / Basu, Shibom (Author) / James, Daniel (Author) / Wang, Dingjie (Author) / Schaffer, Alexander (Author) / Roy Chowdhury, Shatabdi (Author) / Zatsepin, Nadia (Author) / Aquila, Andrew (Author) / Coe, Jesse (Author) / Gati, Cornelius (Author) / Hunter, Mark S. (Author) / Koglin, Jason E. (Author) / Kupitz, Christopher (Author) / Nelson, Garrett (Author) / Subramanian, Ganesh (Author) / White, Thomas A. (Author) / Zhao, Yun (Author) / Zook, James (Author) / Boutet, Sebastien (Author) / Cherezov, Vadim (Author) / Spence, John (Author) / Fromme, Raimund (Author) / Weierstall, Uwe (Author) / Fromme, Petra (Author) / Department of Chemistry and Biochemistry (Contributor) / Biodesign Institute (Contributor) / Applied Structural Discovery (Contributor) / College of Liberal Arts and Sciences (Contributor) / Department of Physics (Contributor) / School of Molecular Sciences (Contributor)
Created2015-06-30
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Description
X-ray free-electron lasers (XFELs) provide new opportunities for structure determination of biomolecules, viruses and nanomaterials. With unprecedented peak brilliance and ultra-short pulse duration, XFELs can tolerate higher X-ray doses by exploiting the femtosecond-scale exposure time, and can thus go beyond the resolution limits achieved with conventional X-ray diffraction imaging techniques.

X-ray free-electron lasers (XFELs) provide new opportunities for structure determination of biomolecules, viruses and nanomaterials. With unprecedented peak brilliance and ultra-short pulse duration, XFELs can tolerate higher X-ray doses by exploiting the femtosecond-scale exposure time, and can thus go beyond the resolution limits achieved with conventional X-ray diffraction imaging techniques. Using XFELs, it is possible to collect scattering information from single particles at high resolution, however particle heterogeneity and unknown orientations complicate data merging in three-dimensional space. Using the Linac Coherent Light Source (LCLS), synthetic inorganic nanocrystals with a core–shell architecture were used as a model system for proof-of-principle coherent diffractive single-particle imaging experiments. To deal with the heterogeneity of the core–shell particles, new computational methods have been developed to extract the particle size and orientation from the scattering data to assist data merging. The size distribution agrees with that obtained by electron microscopy and the merged data support a model with a core–shell architecture.
ContributorsLi, Xuanxuan (Author) / Spence, John (Author) / Hogue, Brenda (Author) / Liu, Haiguang (Author) / College of Liberal Arts and Sciences (Contributor) / Department of Physics (Contributor) / Biodesign Institute (Contributor) / Applied Structural Discovery (Contributor)
Created2017-08-27
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Description

A distinct pathovar of Salmonella enterica serovar Typhimurium, ST313, has emerged in sub-Saharan Africa as a major cause of fatal bacteremia in young children and HIV-infected adults. D23580, a multidrug resistant clinical isolate of ST313, was previously shown to have undergone genome reduction in a manner that resembles that of

A distinct pathovar of Salmonella enterica serovar Typhimurium, ST313, has emerged in sub-Saharan Africa as a major cause of fatal bacteremia in young children and HIV-infected adults. D23580, a multidrug resistant clinical isolate of ST313, was previously shown to have undergone genome reduction in a manner that resembles that of the more human-restricted pathogen, Salmonella enterica serovar Typhi. It has since been shown through tissue distribution studies that D23580 is able to establish an invasive infection in chickens. However, it remains unclear whether ST313 can cause lethal disease in a non-human host following a natural course of infection. Herein we report that D23580 causes lethal and invasive disease in a murine model of infection following peroral challenge. The LD50 of D23580 in female BALB/c mice was 4.7 x 105 CFU. Tissue distribution studies performed 3 and 5 days post-infection confirmed that D23580 was able to more rapidly colonize the spleen, mesenteric lymph nodes and gall bladder in mice when compared to the well-characterized S. Typhimurium strain SL1344. D23580 exhibited enhanced resistance to acid stress relative to SL1344, which may lend towards increased capability to survive passage through the gastrointestinal tract as well as during its intracellular lifecycle. Interestingly, D23580 also displayed higher swimming motility relative to SL1344, S. Typhi strain Ty2, and the ST313 strain A130. Biochemical tests revealed that D23580 shares many similar metabolic features with SL1344, with several notable differences in the Voges-Proskauer and catalase tests, as well alterations in melibiose, and inositol utilization. These results represent the first full duration infection study using an ST313 strain following the entire natural course of disease progression, and serve as a benchmark for ongoing and future studies into the pathogenesis of D23580.

ContributorsYang, Jiseon (Author) / Barrila, Jennifer (Author) / Roland, Kenneth (Author) / Kilbourne, Jacquelyn (Author) / Ott, C. Mark (Author) / Forsyth, Rebecca (Author) / Nickerson, Cheryl (Author) / ASU Biodesign Center Immunotherapy, Vaccines and Virotherapy (Contributor) / Biodesign Institute (Contributor)
Created2015-06-19
Description

The Journal of Surrealism and the Americas: Vol. 1 No. 1 (2007) - Table of Contents

"Introduction to the Journal" by Samantha Kavky, Claudia Mesch, and Amy H. Winter, p. i-iii.

"Anti-Surrealist Cross-Word Puzzles: Breton, Dalí and Print in Wartime America" by Julia Pine, p. 1-29.

"William Carlos Williams’ A Novelette: an American

The Journal of Surrealism and the Americas: Vol. 1 No. 1 (2007) - Table of Contents

"Introduction to the Journal" by Samantha Kavky, Claudia Mesch, and Amy H. Winter, p. i-iii.

"Anti-Surrealist Cross-Word Puzzles: Breton, Dalí and Print in Wartime America" by Julia Pine, p. 1-29.

"William Carlos Williams’ A Novelette: an American Counterproposal to French Surrealism" by Céline Mansanti, p. 30-43

"The Vernacular as Vanguard: Alfred Barr, Salvador Dalí, and the U.S. Reception of Surrealism in the 1930s" by Sandra Zalman, p. 44-67

"Ben Cobb, Anarchy and Alchemy: The Films of Alejandro Jodorowsky" by David Church, p. 68-71

"Tamayo: A Modern Icon Reinterpreted" by Marta Julia Clapp, p. 72-76

"Robert Desnos, Surrealism, and 'Poetic Politics'" by Terri J. Gordon, p. 77-80

"Dali and the Specter of Cinema" by Frédérique Camille Joseph-Lowery, p. 81-84

"Julia Kelly's Art, Ethnography and the Life of Objects: Paris, c. 1925-1935" by Susan Power, p. 85-90

"The Janus-faced Legacy of Joseph Beuys" by Tatjana Myoko von Prittwitz, p. 91-93

"A.J. Meek, Clarence John Laughlin: Prophet Without Honor" by Jeffrey Ian Ross, p. 94-98

 

ContributorsKavky, Samantha (Author) / Mesch, Claudia (Author) / Winter, Amy H. (Author) / Pine, Julia (Author) / Mansanti, Céline (Author) / Zalman, Sandra (Author) / Church, David (Author) / Clapp, Marta Julia (Author) / Gordon, Terri J. (Author) / Joseph-Lowery, Frédérique Camille (Author) / Power, Susan (Author) / von Prittwitz, Tatjana Myoko (Author) / Ross, Jeffrey Ian (Author)
Created2007
The Journal of Surrealism and the Americas: Vol. 2 No. 1 (2008)
Description

The Journal of Surrealism and the Americas: Vol. 2 No. 1 (2008) - Table of Contents

“Surrealism and Ethnography: Introduction” by Amy H. Winter, p. i-vi. 

“Totemic Landscapes and Vanishing Cultures Through the Eyes of Wolfgang Paalen and Kurt Seligmann” by Marie Mauzé, p. 1-24.

“Surrealist Visions of Pre-Columbian Mesoamerica and the Legacy

The Journal of Surrealism and the Americas: Vol. 2 No. 1 (2008) - Table of Contents

“Surrealism and Ethnography: Introduction” by Amy H. Winter, p. i-vi. 

“Totemic Landscapes and Vanishing Cultures Through the Eyes of Wolfgang Paalen and Kurt Seligmann” by Marie Mauzé, p. 1-24.

“Surrealist Visions of Pre-Columbian Mesoamerica and the Legacy of Colonialism: the Good, the (Revalued) Bad, and the Ugly” by Keith Jordan, p. 25-63.

“Surrealism and Inuit Art: The Fascination of the Far North” by Florence Duchemin-Pelletier, p. 64-94.

“Bound Objects and Blurry Boundaries: Surrealist Display and (Anti)Nationalism” by Susan Power, p. 95-113.

“Man Ray’s Lost and Found Photographs: Arts of the Americas in Context” by Wendy Grossman, p. 114-139.

“T.J. Demos, The Exiles of Marcel Duchamp” by Bradley Bailey, p. 140-144. 

“The Dalí Renaissance: New Perspectives on His Life and Art after 1940 and Danser Gala: L’Art Bouffe de Salvador Dalí” by Mary Ann Caws, p. 145-146.

“Review of ‘The Art of Lee Miller’: Victoria and Albert Museum, 2007” by Peter Barberie, p. 147-151.

“Frida Kahlo in Philadelphia: Life and Death” by Samantha Kavky, p. 152-156.

“Thinking the ‘Post-Indian’: Remix: New Modernities in a Post-Indian World” by Claudia Mesch, p. 157-161.

ContributorsWinter, Amy H. (Author) / Mauzé, Marie (Author) / Jordan, Keith (Author) / Duchemin-Pelletier, Florence (Author) / Power, Susan (Author) / Grossman, Wendy A. (Author) / Mesch, Claudia (Author, Author) / Bailey, Charles Bradley (Author) / Caws, Mary Ann (Author) / Barberie, Peter (Author) / Kavky, Samantha (Author)
Created2008
Description

The Journal of Surrealism and the Americas: Vol. 4 No. 1 (2010) - Table of Contents

“Out of Field (Fuera de campo): Marcel Duchamp in Buenos Aires” by Graciela Speranza, p. 1-14. 

“Légitime défense: From Communism and Surrealism to Caribbean Self-Definition” by Lori Cole, p. 15-30. 

“Remedios Varo's Mexican Drawings” by Rosa Berland,

The Journal of Surrealism and the Americas: Vol. 4 No. 1 (2010) - Table of Contents

“Out of Field (Fuera de campo): Marcel Duchamp in Buenos Aires” by Graciela Speranza, p. 1-14. 

“Légitime défense: From Communism and Surrealism to Caribbean Self-Definition” by Lori Cole, p. 15-30. 

“Remedios Varo's Mexican Drawings” by Rosa Berland, p. 30-42.

“Bee Dreaming: the Surreal Odysseys Behind Alan Glass’ Wunderkabinetts” by Gloria Orenstein, p. 43-59.

“Review of Patricia Allmer, ‘René Magritte: Beyond Painting’ by Terri Geis, p. 60-63.

“Review of Eric Ratcliffe, ‘Ithell Colquhoun: Pioneer Surrealist, Artist, Occultist, Writer and Poet’” by Elisabeth Sherman, p. 64-68. 

“‘Arshile Gorky: A Retrospective’: Issues of Identity and Camouflage” by Samantha Kavky, p. 69-72.

“Review of Catherine Millet, ‘Dalí and Me’” by Jonathan S. Wallis, p. 73-77.

“Maria Martins: the Open Secret of Étant donnés. Review of ‘Marcel Duchamp. Étant donnés’” by Frédérique Joseph-Lowery, p. 78-85. 

ContributorsSperanza, Graciela (Author) / Cole, Lori (Author) / Berland, Rosa (Author) / Orenstein, Gloria (Author) / Geis, Terri Lynn (Author) / Sherman, Elisabeth (Author) / Kavky, Samantha (Author) / Wallis, Jonathan S. (Author) / Joseph-Lowery, Frédérique Camille (Author)
Created2010
Description

The Journal of Surrealism and the Americas: Vol. 10 No. 1 (2019) - Table of Contents

“Introduction to the Special Issue on Max Ernst” by Samantha Kavky, p. 1-6. 

“Napoleon in the Wilderness: The Transmogrification of a Picture by Max Ernst” by Martin Schieder, p. 7-23.

“Seeing Through an (American) Temperament: Max Ernst’s

The Journal of Surrealism and the Americas: Vol. 10 No. 1 (2019) - Table of Contents

“Introduction to the Special Issue on Max Ernst” by Samantha Kavky, p. 1-6. 

“Napoleon in the Wilderness: The Transmogrification of a Picture by Max Ernst” by Martin Schieder, p. 7-23.

“Seeing Through an (American) Temperament: Max Ernst’s Microbes, 1946-1953” by Danielle M. Johnson, p. 24-45. 

“Max Ernst and the Aesthetic of Commercial Tourism: Max Among Some of His Favorite Dolls” by Carolyn Butler Palmer, p, 46-68.

“Arizona Dream: Maxime Rossi Meets Max Ernst” by Julia Drost, p. 69-83.

“Glowing Like Phosphorus: Dorothea Tanning and the Sedona Western” by Catriona McAra, p. 84-105.

“Conference Review: ‘SURREALISMS: the Inaugural Conference of the International Society for the Study of Surrealism’” by Kristen Strange, p. 106-110. 

“Exhibition Review of ‘A Home for Surrealism: Fantastic Painting in Midcentury Chicago’” by Jennifer R. Cohen, p. 111-114.

“Exhibition Review: ‘Native American Art at Documenta 14 and the Issue of Democracy’” by Claudia Mesch, p. 115-120.   

ContributorsKavky, Samantha (Author) / Schieder, Martin (Author) / Johnson, Danielle M. (Author) / Palmer, Carolyn Butler (Author) / Drost, Julia, 1969- (Author) / McAra, Catriona (Author) / Strange, Kristen (Author) / Cohen, Jennifer R. (Author) / Mesch, Claudia (Author)
Created2019
Description

The Journal of Surrealism and the Americas: Vol. 6 No. 1 (2012) - Table of Contents

“Notes for a Historiography of Surrealism in America, or the Reinterpretation of the Repressed” by Samantha Kavky, p. i-ix.

“What Makes a Collection Surrealist?: Twentieth-Century Cabinets of Curiosities in Paris and Houston” by Katharine Conley, p. 1-23.

Dalí, Magritte,

The Journal of Surrealism and the Americas: Vol. 6 No. 1 (2012) - Table of Contents

“Notes for a Historiography of Surrealism in America, or the Reinterpretation of the Repressed” by Samantha Kavky, p. i-ix.

“What Makes a Collection Surrealist?: Twentieth-Century Cabinets of Curiosities in Paris and Houston” by Katharine Conley, p. 1-23.

Dalí, Magritte, and Surrealism’s Legacy, New York c. 1965” by Sandra Zalman, p. 24-38.

“‘What Makes Indians Laugh’: Surrealism, Ritual, and Return in Steven Yazzie and Joseph Beuys” by Claudia Mesch, p. 39-60. 

“Cracking up an Alligator: Ethnography, Juan Downey’s Videos, and Irony” by Hjorleifur Jonsson, p. 61-86.

“Review of Effie Rentzou, ‘Littérature Malgré Elle: Le Surréalisme et la Transformation du Littéraire’” by Pierre Taminiaux, p. 87-90.

“In Wonderland: the Surrealist Adventures of Women Artists in Mexico and the United States” by Susan L. Aberth, p. 91-94.

ContributorsKavky, Samantha (Author) / Conley, Katharine (Author) / Zalman, Sandra (Author) / Mesch, Claudia (Author) / Jonsson, Hjorleifur (Author) / Taminiaux, Pierre (Author) / Aberth, Susan Louise (Author)
Created2012
Description

The Journal of Surrealism and the Americas: Vol. 9 No. 1 (2016) - Table of Contents

“Anemic Cinema: Dada/Surrealism and Film in the Americas: Introduction to the Cinema Issue” by Samantha Kavky, p. i-iii.

“‘Polycythemia,’ or Surrealist Intertextuality in the Light of Cinematic ‘Anemia’” by Robert J. Belton, p. 1-13.

“Modern Architecture Will

The Journal of Surrealism and the Americas: Vol. 9 No. 1 (2016) - Table of Contents

“Anemic Cinema: Dada/Surrealism and Film in the Americas: Introduction to the Cinema Issue” by Samantha Kavky, p. i-iii.

“‘Polycythemia,’ or Surrealist Intertextuality in the Light of Cinematic ‘Anemia’” by Robert J. Belton, p. 1-13.

“Modern Architecture Will Help You” by Ana María León, p, 14-39. 

“Radio Transmission: Electricity and Surrealist Art in 1950s and ‘60s San Francisco” by R. Bruce Elder, p. 40-61.

“Surrealism in the Autobiographical Cinema of Alejandro Jodorowsky: Dance of Reality (La Danza de la realidad, 2013) and Endless Poetry (Poesía sin fin, 2016)” by George Melnyk, p. 62-66. 

“Review of Wolfgang Paalen, ‘Form and Sense’ with an Introduction by Martica Sawin” by Ellen G. Landau, p. 67-72. 

ContributorsKavky, Samantha (Author) / Belton, Robert James, 1953- (Author) / León, Ana María (Author) / Elder, Bruce (R. Bruce) (Author) / Melnyk, George (Author) / Landau, Ellen G. (Author)
Created2016
Description

The purpose of this project was to evaluate the State Bar of New Mexico's (SBNM) new podcast series, SBNM is Hear. The podcast was initially developed as a member outreach tool and a new platform for professional development and survey questions were developed to gauge the podcast’s effectiveness in these

The purpose of this project was to evaluate the State Bar of New Mexico's (SBNM) new podcast series, SBNM is Hear. The podcast was initially developed as a member outreach tool and a new platform for professional development and survey questions were developed to gauge the podcast’s effectiveness in these two areas. An electronic survey was deployed to active members of the SBNM through email. Respondents were asked questions regarding their demographics, whether they had listened to the series, and what content they would like to hear in the future. The survey resulted in 103 responses, of which 60% indicated that they had not listened to the podcast. The results showed that listenership was evenly divided between generations and that more females listened to at least one episode. The open-ended responses indicated that the two cohorts of respondents (listeners and non- listeners) viewed the podcast a potential connection to the New Mexico judiciary. Future recommendations include conducting an annual survey to continue to understand the effectiveness of the podcast and solicit feedback for continued growth and improvement

ContributorsPettit, Morgan (Author) / Lauer, Claire (Degree committee member) / Mara, Andrew (Degree committee member) / Carradini, Stephen (Degree committee member)
Created2020-12-10