In the middle of the COVID-19 epidemic, flaws in the SARS-CoV-2 diagnostic
test were identified by the impending supply shortages of nasopharyngeal swabs and nucleic acid isolation and purification kits. The ASU Biodesign Clinical Testing Lab (ABCTL), which converted from a research lab to SARS-CoV-2 testing lab, was not an exception to these shortages, but the consequences were greater due to its significant testing load in the state of Arizona. In response to the shortages, researchers at The Department of Epidemiology of Microbial Diseases, at the Yale School of Public Health created SalivaDirect method, which is an epidemic effective test, that accounts for limitations of materials, accessibility to specialized lab equipment, time per test, and cost per test. SalivaDirect simplified the diagnostic process by collecting samples via saliva and skipping the nucleic acid extraction and purification, and did it in a way that resulted in a highly sensitive limit of detection of 6-12 SARS-CoV-2 copies/μL with a minimal decrease in positive test agreement.

The ASU Biodesign Clinical Testing Laboratory began in March 2020 after the severe acute respiratory syndrome, coronavirus 2, began spreading throughout the world. ASU worked towards implementing  its own efficient way of testing for the virus, in order to assist the university but also keep the communities around it safe. By developing its own strategy for COVID-19 testing, ASU was on the forefront of research by developing new ways to test for the virus. This process began when research labs at ASU were quickly converted into clinical testing laboratories, which used saliva testing to develop swift COVID-19 diagnostic tests for the Arizona community. The lab developed more accurate and time efficient results, while also converting Nasopharyngeal tests to saliva tests. Not only did this allow for fewer amounts of resources required, but more individuals were able to get tested at faster rates. The ASU Biodesign Clinical Testing Laboratory (ABCTL) was able to accomplish this through the adaptation of previous machines and personnel to fit the testing needs of the community. In the future, the ABCTL will continue to adapt to the ever-changing needs of the community in regards to the unprecedented COVID-19 pandemic. The research collected throughout the past year following the breakout of the COVID-19 pandemic is a reflection of the impressive strategy ASU has created to keep its communities safe, while continuously working towards improving not only the testing sites and functions, but also the ways in which an institution approaches and manages an unfortunate impact on diverse communities.

This thesis project is part of a larger collaboration documenting the history of the ASU Biodesign Clinical Testing Laboratory (ABCTL). There are many different aspects that need to be considered when transforming to a clinical testing laboratory. This includes the different types of tests performed in the laboratory. In addition to the diagnostic polymerase chain reaction (PCR) test that is performed detecting the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), antibody testing is also performed in clinical laboratories. Antibody testing is used to detect a previous infection. Antibodies are produced as part of the immune response against SARS-CoV-2. There are many different forms of antibody tests and their sensitives and specificities have been examined and reviewed in the literature. Antibody testing can be used to determine the seroprevalence of the disease which can inform policy decisions regarding public health strategies. The results from antibody testing can also be used for creating new therapeutics like vaccines. The ABCTL recognizes the shifting need of the community to begin testing for previous infections of SARS-CoV-2 and is developing new forms of antibody testing that can meet them.

This thesis was conducted to study and analyze the fund allocation process adopted by different states in the United States to reduce the impact of the Covid-19 virus. Seven different states and their funding methodologies were compared against the case count within the state. The study also focused on development of a physical distancing index based on three significant attributes. This index was then compared to the expenditure and case counts to support decision making.
A regression model was developed to analyze and compare how different states case counts played out against the regression model and the risk index.

In mid-March of 2020, Arizona State University transformed one of its research labs into ASU Biodesign Clinical Testing Laboratory (ABCTL) to meet the testing needs of the surrounding community during the COVID-19 pandemic. The lab uses RT-qPCR, or reverse transcription polymerase chain reaction, to match the components of a biosample to a portion of the SARS-CoV-2 genome. The ABCTL uses the TaqPath™ COVID-19 Combo Kit, which has undergone many different types of efficacy and efficiency tests and can successfully denote saliva samples as positive even when an individual is infected with various emerging strains of the SARS-CoV-2. Samples are collected by volunteers at testing sites with stringent biosafety precautions and processed in the lab using specific guidelines. As the pandemic eventually becomes less demanding, the ABCTL plans to utilize the Devil’s Drop-off program at various school districts around Arizona to increase testing availability, transfer to the SalivaDirect method, and provide other forms of pathogen testing to distinguish COVID-19 from other types of infections in the ASU community.

The ASU COVID-19 testing lab process was developed to operate as the primary testing site for all ASU staff, students, and specified external individuals. Tests are collected at various collection sites, including a walk-in site at the SDFC and various drive-up sites on campus; analysis is conducted on ASU campus and results are distributed virtually to all patients via the Health Services patient portal. The following is a literature review on past implementations of various process improvement techniques and how they can be applied to the ABCTL testing process to achieve laboratory goals. (abstract)

The U.S. Navy and other amphibious military organizations utilize a derivation of the traditional side stroke called the Combat Side Stroke, or CSS, and tout it as the most efficient technique available. Citing its low aerobic requirements and slow yet powerful movements as superior to the traditionally-best front crawl (freestyle), the CSS is the go-to stroke for any operation in the water. The purpose of this thesis is to apply principles of Industrial Engineering to a real-world situation not typically approached from a perspective of optimization. I will analyze pre-existing data about various swim strokes in order to compare them in terms of efficiency for different variables. These variables include calories burned, speed, and strokes per unit distance, as well as their interactions. Calories will be measured by heart rate monitors, converting BPM to calories burned. Speed will be measured by stopwatch and observer. Strokes per unit distance will be measured by observer. The strokes to be analyzed include the breast stroke, crawl stroke, butterfly, and combat side stroke. The goal is to informally test the U.S. Navy's claim that the combat side stroke is the optimum stroke to conserve energy while covering distance. Because of limitations in the scope of the project, analysis will be done using data collected from literary sources rather than through experimentation. This thesis will include a design of experiment to test the findings here in practical study. The main method of analysis will be linear programming, followed by hypothesis testing, culminating in a design of experiment for future progress on this topic.

The definition of "beauty" can be interpreted in many ways but when defining it literally, it is considered as such: "a combination of qualities that pleases the intellect or moral sense" (Oxford Dictionaries). Beauty simply "pleases" the intellect; it does not say that intellect is a factor of beauty itself. Beauty is nice to look at, a mere pleasure to experience in the "moral sense." It does not have anything to do with one's actions, principles or intelligence, but instead the way one presents himself or herself. If someone is deemed as intellectual, does that mean they are not viewed as beautiful? Is that why beauty is rarely associated with brains and vice versa? Has a history of stereotypes and media interference convinced us that these two concepts cannot coexist? And what if we found out that they did? Could we take that person seriously? I decided to challenge the idea of beauty and brains, and see if beauty is in fact measured by its literal definition and controlled by its assumed stereotype, or if other factors apply when deciphering someone's "beauty." First, I will analyze the perceptions and stereotypes of engineers. By looking at the public opinion of both engineers and women engineers, I can show the common struggles engineers face. Next I will look at perceptions of cheerleaders, in particular, professional cheerleaders. Through analyzing current stereotypes and gender roles associated with these women in the spotlight, I can establish how opinions of these women are formed. I will also look at a survey of a sample of Arizona State University students in which we can confirm or deny the results found through research of previous studies. We will also be able to gather personal opinions about why these stereotypes exist and how to break them down. Finally, we will look at personal accounts of current or retired National Football League (NFL) cheerleaders. These will give first-hand examples of what it is like to be both a cheerleader and a woman in STEM (science, technology, engineering, and mathematics).

In an increasingly global economy, companies face challenges with implementing successful business and marketing strategies in cultures different from their own. This paper calls upon previous research to compile a per-country outline of general behaviors and expectations when doing business overseas. Using categorical definitions from Hofstede's 1984 study and those found in the Handbook of Global and Multicultural Negotiation, a table has been prepared to group similar countries based on their cultural biases.

Perfection is extremely difficult to achieve when playing team sports. This is especially true for lacrosse, a sport where dropped passes, missed shots and turnovers are prevalent even at the college and professional levels of the game. In order to improve on mistakes, teams must first recognize where the errors are being made. The purpose of this project is to implement the DMAIC process improvement method into lacrosse, with the goal of identifying and implementing improvements, leading to a more successful team.
In order to use DMAIC, lacrosse was expressed as a process that included five phases: offense, defense, riding, clearing and faceoffs. Data was gathered for each phase using game film from the Arizona State Men’s Club Lacrosse Team over the course of the 2019 and 2020 seasons. The data was then analyzed by comparing the output statistics of each phase to the goal differential, number of goals scored, and number of goals against. Once the areas of improvement were determined, additional analysis was done to determine why these certain areas needed improvement. The results provided what changes needed to be made in order to improve the team. In order to ensure the team sustained their success, control measures were put in place to determine what action needs to be taken and when.