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Analyzing Incident Rates of COVID-19 Before and After Stay-At-Home Orders Throughout the Southwestern U.S. with Respect to Limited Mobility Models

ContributorsTilleman, Karl Benson (Author) / Albuquerque, Fabio Suzart de (Thesis director) / Powers, Brian (Committee member) / College of Integrative Sciences and Arts (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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Mathematical and analytical approach at the floor and diffuser of a Formula 1 vehicle and how they produce downforce. Reaches a conclusion about how engineers and aerodynamicists creates the desired effects underneath the vehicle to produce substantial downforce.

ContributorsMarcantonio, Nicholas Joseph (Author) / Rajadas, John (Thesis director) / Hillery, Scott (Committee member) / College of Integrative Sciences and Arts (Contributor) / Engineering Programs (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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Preeclampsia is a disease that occurs during pregnancy and affects upwards of 10% of pregnancies around the world (Osungbade & Ige, 2011). African American pregnant women are particularly vulnerable and die at a disproportionate rate compared to other races. In this literature review, three research studies were analyzed to determine

Preeclampsia is a disease that occurs during pregnancy and affects upwards of 10% of pregnancies around the world (Osungbade & Ige, 2011). African American pregnant women are particularly vulnerable and die at a disproportionate rate compared to other races. In this literature review, three research studies were analyzed to determine if African American pregnant women were included in preeclampsia Studies. Only one of the studies included in this review met all criteria by including African American pregnant women. One research study met half of the criteria; however, the authors noted that there was not enough evidence for Black Americans. The third research article also only met half of the criteria. We conclude that further studies are needed that include African American women in studies on preeclampsia.

ContributorsCheeks, Maiya (Author) / Lateef, Dalya (Thesis director) / Briggs, Georgette (Committee member) / College of Integrative Sciences and Arts (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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A research project turned creative project focusing on the narrative of the student's perspective in the Next Generation Service Corps scholarship program. Using survey results from the program members, narratives of their experiences were compiled to offer insight and direction for the growth of the program.<br/><br/>A video of the defense

A research project turned creative project focusing on the narrative of the student's perspective in the Next Generation Service Corps scholarship program. Using survey results from the program members, narratives of their experiences were compiled to offer insight and direction for the growth of the program.<br/><br/>A video of the defense can be found at this link: https://youtu.be/O63NRz0z1Ys

ContributorsJanezic, John Henry (Author) / Hunt, Brett (Thesis director) / Smith, Jacqueline (Committee member) / College of Integrative Sciences and Arts (Contributor) / School of International Letters and Cultures (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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An X class solar flare has the potential to remove our satellites from orbit, permanently deactivate our main forms of communication and bring humanity into a technology-free age. By using Geant4, it is possible to simulate several layers of the Earth's atmosphere and send a simulated solar flare and coronal

An X class solar flare has the potential to remove our satellites from orbit, permanently deactivate our main forms of communication and bring humanity into a technology-free age. By using Geant4, it is possible to simulate several layers of the Earth's atmosphere and send a simulated solar flare and coronal mass ejection. This thesis will show the interaction of photons and protons of various energies with several kilometers of atmosphere.

ContributorsDolghier, Kristian Adrian (Author) / Shovkovy, Igor (Thesis director) / Steinkamp, Brian (Committee member) / Economics Program in CLAS (Contributor) / College of Integrative Sciences and Arts (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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The Founders lab is a year-long program that gives its students an opportunity to participate in a unique team-based, experiential Barrett honors thesis project to design and apply marketing and sales strategies, as well as business and financial models to start up and launch a new business. This honors thesis

The Founders lab is a year-long program that gives its students an opportunity to participate in a unique team-based, experiential Barrett honors thesis project to design and apply marketing and sales strategies, as well as business and financial models to start up and launch a new business. This honors thesis project focuses on increasing the rate of vaccination outcomes in a country where people are increasingly busy (less time) and unwilling to get a needle through a new business venture that provides a service that brings vaccinations straight to businesses, making them available for their employees. Through our work with the Founders Lab, our team was able to create this pitch deck.

ContributorsGomez, Isaias Abraham (Co-author) / Hanzlick, Emily (Co-author) / Zatonskiy, Albert (Co-author) / Byrne, Jared (Thesis director) / Hall, Rick (Committee member) / Silverstein, Taylor (Committee member) / College of Integrative Sciences and Arts (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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Bacteria are often regarded s pathogens, with deleterious impacts on the human body. However, it is known that the presence of trillions of bacteria on and in the human body impart beneficial effects on human health. Like a fingerprint, each individual’s microbiome is unique. The composition of bacteria in one

Bacteria are often regarded s pathogens, with deleterious impacts on the human body. However, it is known that the presence of trillions of bacteria on and in the human body impart beneficial effects on human health. Like a fingerprint, each individual’s microbiome is unique. The composition of bacteria in one person’s gut is different from the gut bacteria in another individual. Together, the human gut microbiome is a complex mix of organisms that is commonly referred to as “the second brain.� Its role in the human body goes beyond digestion and immune system function. The health of the microbiome factors into risk for illnesses as diverse as depression, obesity, bowel disorders and autism (Perlmutter et al., 2015). In context of the myriad of bacteria that live on and within the human body, the composition of bacteria in the gut may have the most significant impact on an individual’s well-being. This “superorganism� co-evolved with its host in order to provide essential and mutually beneficial functions (Ragonnaud et al., 2021).

Affecting millions of Americans, depression is one of the leading causes of the Global Burden of Disease (GBD), followed by anxiety (Gibson-Smith et al., 2018). Communication that occurs between the human brain and the gut microbiome has been found to be a major contributor towards mental health. The human gut microbiome is comprised of many microbes that can communicate with the brain through the gut-brain axis. However, factors such as stress and diets can interfere with this process, especially after increasing the permeability of the intestine (Khoshbin et al., 2020). Perturbation of the gut-brain axis has been implicated across a wide scale of neurodegenerative disorders, with respect to psychopathology (Bonaz et al., 2018). The environment of the gut, along with which species reside there, can help determine the link between gut function and disease. Therefore, it may be possible to prevent the degradation of an individual’s immune function and well-being through alteration of the gut microbiome. (abstract)
ContributorsPisarczyk, Nicole (Author) / Penton, Christopher (Thesis director) / Huffman, Holly (Committee member) / College of Integrative Sciences and Arts (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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This dissertation investigates the condition of skeletal muscle insulin resistance using bioinformatics and computational biology approaches. Drawing from several studies and numerous data sources, I have attempted to uncover molecular mechanisms at multiple levels. From the detailed atomistic simulations of a single protein, to datamining approaches applied at the systems

This dissertation investigates the condition of skeletal muscle insulin resistance using bioinformatics and computational biology approaches. Drawing from several studies and numerous data sources, I have attempted to uncover molecular mechanisms at multiple levels. From the detailed atomistic simulations of a single protein, to datamining approaches applied at the systems biology level, I provide new targets to explore for the research community. Furthermore I present a new online web resource that unifies various bioinformatics databases to enable discovery of relevant features in 3D protein structures.
ContributorsMielke, Clinton (Author) / Mandarino, Lawrence (Committee member) / LaBaer, Joshua (Committee member) / Magee, D. Mitchell (Committee member) / Dinu, Valentin (Committee member) / Willis, Wayne (Committee member) / Arizona State University (Publisher)
Created2013
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While exercising mammalian muscle increasingly relies on carbohydrates for fuel as aerobic exercise intensity rises above the moderate range, flying birds are extraordinary endurance athletes and fuel flight, a moderate-high intensity exercise, almost exclusively with lipid. In addition, Aves have long lifespans compared to weight-matched mammals. As skeletal muscle mitochondria

While exercising mammalian muscle increasingly relies on carbohydrates for fuel as aerobic exercise intensity rises above the moderate range, flying birds are extraordinary endurance athletes and fuel flight, a moderate-high intensity exercise, almost exclusively with lipid. In addition, Aves have long lifespans compared to weight-matched mammals. As skeletal muscle mitochondria account for the majority of oxygen consumption during aerobic exercise, the primary goal was to investigate differences in isolated muscle mitochondria between these species and to examine to what extent factors intrinsic to mitochondria may account for the behavior observed in the intact tissue and whole organism. First, maximal enzyme activities were assessed in sparrow and rat mitochondria. Citrate synthase and aspartate aminotransferase activity were higher in sparrow compared to rat mitochondria, while glutamate dehydrogenase activity was lower. Sparrow mitochondrial NAD-linked isocitrate dehydrogenase activity was dependent on phosphate, unlike the mammalian enzyme. Next, the rate of oxygen consumption (JO), electron transport chain (ETC) activity, and reactive oxygen species (ROS) production were assessed in intact mitochondria. Maximal rates of fat oxidation were lower than for carbohydrate in rat but not sparrow mitochondria. ETC activity was higher in sparrows, but no differences were found in ROS production between species. Finally, fuel selection and control of respiration at three rates between rest and maximum were assessed. Mitochondrial fuel oxidation and selection mirrored that of the whole body; in rat mitochondria the reliance on carbohydrate increased as the rate of oxygen consumption increased, whereas fat dominated under all conditions in the sparrow. These data indicate fuel selection, at least in part, can be modulated at the level of the mitochondrial matrix when multiple substrates are present at saturating levels. As an increase in matrix oxidation-reduction potential has been linked to a suppression of fat oxidation and high ROS production, the high ETC activity relative to dehydrogenase activity in avian compared to mammalian mitochondria may result in lower matrix oxidation-reduction potential, allowing fatty acid oxidation to proceed while also resulting in low ROS production in vivo.
ContributorsKuzmiak, Sarah (Author) / Willis, Wayne T (Thesis advisor) / Mandarino, Lawrence (Committee member) / Sweazea, Karen (Committee member) / Harrison, Jon (Committee member) / Gadau, Juergen (Committee member) / Arizona State University (Publisher)
Created2012
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This thesis looks at how Latinx communities in Wyoming, despite recognizing the impossibility of overcoming the traditional conservative autocracy, still utilize their identity as a political response to unify Latinx communities throughout the state. The project draws from oral histories conducted with Latinx/Chicanx community members in Wyoming, including professors, legislators,

This thesis looks at how Latinx communities in Wyoming, despite recognizing the impossibility of overcoming the traditional conservative autocracy, still utilize their identity as a political response to unify Latinx communities throughout the state. The project draws from oral histories conducted with Latinx/Chicanx community members in Wyoming, including professors, legislators, and everyday citizens.

ContributorsFranco, David (Author) / Fonseca-Chávez, Vanessa (Thesis director) / Martínez, Rafael (Committee member) / College of Integrative Sciences and Arts (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2021-05