Matching Items (191)
Description
Hygiene stigma can exist in tandem to gender stigma which could mean the marginalization of certain groups due to stigmatized identities, specifically women. The marginalization of women is important because of the United Nations Sustainable Development Goal 5: Empowering women and girls and achieving equity. Figuring out how hygiene stigma specifically affects women in Fiji required researching the effects of hygiene stigma, gender inequity and indigenous Fijian societies could influence respondents’ answers. After researching these different topics, these questions were developed: does hygiene stigma and gendered stigma have an overlap? If so, are men more biased than women when it comes to objectifying women? Do indigenous Fijian societies possess an immunity to objectifying women since are considered to have Fijian women have more agency? The data was retrieved from the Global Ethnohydrology Study from 2015-16 in the Viti Levu, Fiji, which was specifically researching whether hygiene stigma is an effective method of helping people have better hygiene norms. A thematic analysis was then conducted, and the data was coded. Based on the results from 28 respondents we were able to conclude that there is gendered stigma within Fijian populations. We found that both men and women objectified women at similar rates and Fiji is not immune to hygiene stigma. The limitations to this analysis were there was no statistical analysis to find correlations hygiene stigma and gendered stigma. There was only one specific code that was being analyzed in this research project which limits the other types of stigma that may exist.
ContributorsKibuka Musoke, Paula Kulabako (Author) / Wutich, Amber (Thesis director) / Schuster, Roseanne (Committee member) / Brewis Slade, Alexandra (Committee member) / School of Molecular Sciences (Contributor) / School of Human Evolution & Social Change (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
Cleavage and polyadenylation is a step in mRNA processing in which the 3’UTR is cleaved and a polyA tail is added to create a final mature transcript. This process relies on RNA sequence elements that guide a large multimeric protein complex named the Cleavage and Polyadenylation Complex to dock on the 3’UTR and execute the cleavage reaction. Interactions of the complex with the RNA and specific dynamics of complex recruitment and formation still remain largely uncharacterized. In our lab we have identified an Adenosine residue as the nucleotide most often present at the cleavage site, although it is unclear whether this specific element is a required instructor of cleavage and polyadenylation. To address whether the Adenosine residue is necessary and sufficient for the cleavage and polyadenylation reaction, we mutated this nucleotide at the cleavage site in three C. elegans protein coding genes, forcing the expression of these wt and mutant 3’UTRs, and studied how the cleavage and polyadenylation machinery process these genes in vivo. We found that interrupting the wt sequence elements found at the cleavage site interferes with the cleavage and polyadenylation reaction, suggesting that the sequence close to the end of the transcript plays a role in modulating the site of the RNA cleavage. This activity is also gene-specific. Genes such as ges-1 showed little disruption in the cleavage of the transcript, with similar location occurring in both the wt and mutant 3’UTRs. On the other hand, mutation of the cleavage site in genes such as Y106G6H.9 caused the activation of new cryptic cleavage sites within the transcript. Taken together, my experiments suggest that the sequence elements at the cleavage site somehow participate in the reaction to guide the cleavage reaction to occur at an exact site. This work will help to better understand the mechanisms of transcription termination in vivo and will push forward research aimed to study post-transcriptional gene regulation in eukaryotes.
ContributorsSteber, Hannah Suzanne (Author) / Mangone, Marco (Thesis director) / Harris, Robin (Committee member) / LaBaer, Joshua (Committee member) / School of Life Sciences (Contributor, Contributor) / School of Mathematical and Statistical Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
Research has been conducted analyzing factors that affect mental health in regions that suffer from water insecurity and water scarcity. Amber Wutich and Alexandra Brewis (2019) explain the effects that water scarcity has on mental health and how chronic worry can trigger depression, stress, anxiety and in extreme cases this can lead to suicidal thoughts. Bina Agarwal (2000) analyzes gender roles in relation to water insecurity where women express more signs of anxiety and worry due to the limited options they have when seeking water outside their household. There are limited studies done on water insecurity at a household level which limit an understanding of possible coping mechanisms along with additional factors that affect mental health. In this study, surveys are conducted in the city of San Juan Del Rio, Queretaro in Mexico where residents have been affected by massive flooding’s. Additionally, residents in Mexico not only suffer from water scarcity but also from poor water infrastructure, constant water outages, shortages, and contaminated water supply. Respondents answers (n=23) regarding the amount of worry, household size, being head of household, and gender was used to conduct paired sample statistical tests where associations were determined. Associations relating to the amount of worry resulted in the idea that residents in San Juan Del Rio because they consistently struggle with water shortages, have developed a coping strategy to deal with water outages and therefore, show fewer signs of worry when faced with a household water situation. In consideration, surveys conducted in surrounding towns and in a rural setting can provide additional information regarding how poverty is related to mental health and water scarcity along with a deeper understanding of possible coping strategies at a household level.
ContributorsRamirez Arellanes, Andrea (Author) / Wutich, Amber (Thesis director) / Brewis, Alexandra (Committee member) / School of Human Evolution & Social Change (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
As obesity rates continue to rise, societal stigmas against individuals classified as "fat" or "obese" also rise. The topics of obesity, fat stigma, slim body ideals, body dissatisfaction and fat talk are all closely interwoven and are heavily influenced by countless human factors. This project attempts to find cross-cultural patterns in female self-perceptions and body preferences across nine culturally and economically diverse countries using both quantitative and qualitative analyses. The nine different countries included in this study are the United States, the United Kingdom, New Zealand, Iceland, Tajikistan, Paraguay, Guatemala, Japan, and South Korea. This study analyzes how satisfied women are with their current size and whether they feel as though they are judged for their size or shape.
ContributorsNiesluchowski, Monet Nazilla (Author) / Wutich, Amber (Thesis director) / Schuster, Roseanne (Committee member) / School of Human Evolution and Social Change (Contributor) / School of Politics and Global Studies (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
Climate change presents a significant threat to human health, both mental and physical; as a result, it has become one of the most commonly discussed phenomena of the 21st century. As many people are aware, a wide range of social and physical factors affects mental health. However, many people fail to realize that these increases global temperatures also have a significant impact on mental health as a result of increased vulnerability that is often manifested through one's emotions. By analyzing perceptions of people across the globe, in the United Kingdom, New Zealand, and Fiji, we were able to pinpoint these emotions and trace them individual's feelings of worry, distress, and hope that resulted from their perceived impacts on climate change. Overall, we found that people tend to have overall more negative emotional reaction when it comes to the perceived effects of climate change. Of the respondents, more men than women expressed concern regarding the various negative implications. Finally, those in the United Kingdom exhibited a stronger emotional response, followed by those in New Zealand and Fiji, respectively.
ContributorsSmith, Austin Lee (Author) / Wutich, Amber (Thesis director) / du Bray, Margaret (Committee member) / Department of Psychology (Contributor) / Sanford School of Social and Family Dynamics (Contributor) / School of Life Sciences (Contributor) / School of Human Evolution and Social Change (Contributor) / Barrett, The Honors College (Contributor)
Created2017-05
Description
The number of undergraduate students participating in short-term experiences in global health (STEGHs) abroad has increased dramatically in recent years (Eyler 2002, Drain et al. 2007). These experiences, in tandem with classroom learning, are designed to help students master skills related to global health competencies, including cultural humility and sensitivity, collaborating with community partners, and sociocultural and political awareness. Although STEGHs offer potential benefits to both students and to sending institutions, these experiences can sometimes be problematic and raise ethical challenges. As the number of students engaged in STEGHs continues to increase, it is important to better understand the impact of these programs on student learning. Current ethical and best practice guidelines for STEGHs state that programs should establish evaluation methods to solicit feedback from students both during and on completion of the program (Crump et al. 2010). However, there is currently no established method for gathering this feedback because of the many different global health competency frameworks, types and duration of programs, and different models of student engagement in such programs. Assessing the quality of a STEGH is a profoundly important and difficult question that cannot be answered as succinctly and quantitatively as classroom performance, which has more standard and established assessment metrics. The goal of this project is to identify the most appropriate and useful assessment metric(s) for determining educational quality and impact for STEGHs at ASU by comparing a typical quantitative evaluation tool (pre-post survey with brief open-ended questions) to a more in-depth qualitative method (key informant interviews). In performing my analysis I seek to examine if the latter can produce a richer narrative of student experiences to inform ongoing program evaluations. My research questions are: 1. What are the current qualitative and quantitative evaluation methods available to assess student learning during short-term experiences in global health? 2. How can current methodology for assessing student experiences with short-term experiences in global health be adapted to collect the most information from students? 3. How do student knowledge and attitudes change before and after their short-term experience in global health? Why is understanding those changes important for adapting programs? My end goal would be to use these new, optimal assessment methods for gathering student perspectives and experiences to adapt pre-departure trainings and post-experience debriefings for study abroad programs, both of which I believe will lead to more sustainable partnerships and a healthier understanding of global health work for students.
ContributorsHale, Brittany Ann (Author) / Jehn, Megan (Thesis director) / Wutich, Amber (Committee member) / School of Human Evolution and Social Change (Contributor) / School of Social Transformation (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
Previous research on shame and stigma has demonstrated that undesired differences can lead to community divides and produce harmful stereotypes in communities. This is particularly true in the context of hygiene, where shame has been used to try and produce better hygiene, and instead has led to increased levels of hygiene stigma in communities. As part of the 2015 Global Ethnohydrology Study, we asked 66 respondents from rural Guatemala questions about their hygiene behaviors and beliefs. The hygiene behavior data was statistically analyzed in order to test for correlation and differences between different demographics such as gender and age. There are significant differences between both gender and age in relation to hygiene behavior and practices. Gender was the stronger determinant of positive hygiene behavior. Using the definitions of stigma from literature, the results of the hygiene behaviors measured were contextualized in order to form conclusions about hygiene stigma overall in Guatemala.
ContributorsHawkins, Emma Nicole (Author) / Wutich, Amber (Thesis director) / du Bray, Meg (Committee member) / School of International Letters and Cultures (Contributor) / School of Human Evolution and Social Change (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
Description
The Culture, Health, and Environment Lab (CHEL) at Arizona State University uses anthropological methods and field-based studies to research how cultural knowledge may be used to help understand and respond to contemporary environmental and health issues—primarily the global challenges of water insecurity and obesity. In their efforts to research water insecurity and it implications, CHEL has been working on studying water insecurity through the Global Ethnohydrology Study (GES). The Global Ethnohydrology study examines local knowledge and perceptions of water issues, using transdisciplinary methods in a multi-year and cross-country program. In the 2015-2016 study, the GES examined water, hygiene norms, and hygiene stigma. It sought to investigate how hygiene norms are impacted by the level of water security, examining if water-poor communities have laxer laxer or more accommodating hygiene norms. This paper will explore the development of the codebook for this study, following the process in which the qualitative data from the GES 2015 was organized through a series of codes so that it may later be analyzed.
ContributorsPfeiffer, Ainsley Josephine (Author) / Wutich, Amber (Thesis director) / Schuster, Roseanne (Committee member) / School of Human Evolution and Social Change (Contributor) / Barrett, The Honors College (Contributor)
Created2017-05
Description
Nucleic acid polymers have numerous applications in both therapeutics and research to control gene expression and bind biologically relevant targets. However, due to poor biological stability their clinical applications are limited. Chemical modifications can improve both intracellular and extracellular stability and enhance resistance to nuclease degradation. To identify a potential candidate for a highly stable synthetic nucleic acid, the biostability of α-L-threofuranosyl nucleic acid (TNA) was evaluated under simulated biological conditions. TNA contains a four-carbon sugar and is linked by 2’, 3’ phosphodiester bonds. We hypothesized that this distinct chemical structure would yield greater nuclease resistance in human serum and human liver microsomes, which were selected as biologically relevant nuclease conditions. We found that TNA oligonucleotides remained undigested for 7 days in these conditions. In addition, TNA/DNA heteropolymers and TNA/RNA oligonucleotide duplexes displayed nuclease resistance, suggesting that TNA has a protective effect over DNA and RNA. In conclusion TNA demonstrates potential as a viable synthetic nucleic acid for use in numerous clinical and therapeutic applications.
ContributorsCulbertson, Michelle Catherine (Author) / Maley, Carlo (Thesis director) / Mangone, Marco (Committee member) / Larsen, Andrew (Committee member) / School of Molecular Sciences (Contributor) / School of International Letters and Cultures (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
Description
In this project we examine the geographical availability of water resources for persons experiencing homelessness in Phoenix, Arizona, U.S.A. Persons experiencing homelessness spend a significant portion of their time outdoors and as such have a higher risk of dehydration, heat-related illness, and heat stress. Our data was collected using archival data, participant- observation, focal follows with water distributors that serve homeless populations, phone and internet surveys with social service providers, and expert interviews with 14 local service providers. We analyzed this data using methods for thematic coding and geospatial analysis. We find that the sources of water and geographic availability vary across the economic sectors of the population and that they become more unconventional and more difficult to access with further isolation. We conclude that many persons who are experience homelessness have inconsistent and unreliable access to water for hydrating, maintaining hygiene, cooking and cleaning for reasons that are largely due to geographic inaccessibility.
ContributorsWarpinski, Chloe Larue (Author) / Wutich, Amber (Thesis director) / Whelan, Mary (Committee member) / School of Human Evolution and Social Change (Contributor) / School of International Letters and Cultures (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12