Matching Items (266)
Description
Arizona State University and Banner Thunderbird Hospital have partnered to provide pre-med students with an internship at a local emergency department. Students entering into this program will have access to each patient's vital signs, medical imaging, lab tests, and medications. This access presents students with an opportunity to learn about a variety of tools used in the assessment and treatment of emergency room patients. In order to enhance the amount of knowledge students take away from the program, I created a handbook summarizing a variety of diagnostic tests and medications. The first section of the handbook (assessment) is spilt up into the three following categories: vital signs, medical imaging, and lab tests. The second section (treatment) consists of one category, medications. Each section was written with emphasis on basic physiology, and is intended to provide pre-med students with a foundation for building further medical knowledge. Although this handbook was tailored to the information students are most likely to encounter working in Banner Thunderbird Hospital's emergency department, it is still appropriate for any student interested in learning about emergency medicine.
ContributorsBecker, Bryson (Author) / Orchinik, Miles (Thesis director) / Washo-Krupps, Delon (Committee member) / School of Life Sciences (Contributor) / W.P. Carey School of Business (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
This creative group project aims to bring visibility to the diversity of the LGBTQ+ community at Arizona State University by sharing the personal stories and opinions of people from across ASU's rainbow spectrum. Created and produced by a gay couple that met in their first year dorm and a passionate ally, gAySU: Exploring Sparky's Rainbow is a compilation of photos, videos, and stories from ASU students, faculty, and staff that identify with the LGBTQ+ community. When reflecting on their own journey over the past three years, gAySU's creators recognized ASU can feel large with many pockets of communities, yet through trial and error over the past 4 years they managed to explore their identities and grow as individuals, as a couple, and as an ally. By sharing their story and the stories of others, it is the hope that gAySU allows its readers and viewers an insight into what it means to be both a Sun Devil and LGBTQ+, and for those new to or anxious to identify with the LGBTQ+ community, to understand they are not alone in their journey and that it is okay to bleed maroon, gold, and all other colors of the rainbow.
ContributorsKing, Shay Scott (Co-author) / Hendricks, Brock (Co-author) / Hom, Claire (Co-author) / Dove-Viebahn, Aviva (Thesis director) / Sanchez, Daniel (Committee member) / W.P. Carey School of Business (Contributor) / School of Politics and Global Studies (Contributor) / Department of Supply Chain Management (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
This thesis explores the various reasons that Broadway musicals fail, or "flop". It goes into detail on several musicals of different genres, and explains what their shortcomings were, whether it be a less-than-perfect book, a weak score, or a production team that was not experienced in the skills that it takes to put together a musical. It discusses how long the shows ran for, or if they ever made it into a Broadway house. It looks at what the audience reception was like for each show, and whether the shows were a success with the tough critics of Broadway. In addition to this, I have recorded several of my peers performing songs from the musicals I have discussed in the written portion of this thesis. This helps to educate an audience on what it would have been like for one of the flop's real performances. The videos also do a wonderful job of communicating what the show sounds like, and how it can make an audience feel or react. Lastly, it gives more insight into why the musicals they are from failed to thrive in front of a Broadway audience. Through my research, I have discovered that creating a musical is possibly one of the most difficult feats a team of creative people can accomplish. There are countless reasons for failure in these shows, but overall, I feel that every failure had something to offer, and because of that, are surely worth celebrating.
ContributorsUrias-Ramonett, Sedona Lee (Author) / Yatso, Toby (Thesis director) / Dreyfoos, Dale (Committee member) / W.P. Carey School of Business (Contributor) / School of Music (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
The story of graphene truly began in what was simply a stub in the journal Physical Review not two years after the end of World War II. In 1947, McGill University physicist P.R. Wallace authored “The Band Theory of Graphite” and attempted to develop a foundation on which the structure-property relationship of graphite could be explored; he calculates the number of free electrons and conductivity of what he describes as “a single hexagonal layer” and “suppos[es] that conduction takes place only in layers” in bulk graphite to predict wave functions, energies at specific atomic sites in the hexagonal lattice, and energy contours using a tight binding approximation for a hypothesized version of what we now call ‘armchair-style’ graphene. While Wallace was the first to explore the band structure and Brillouin Zones of single-layer graphite, the concept of two-dimensional materials was not new. In fact, for years, it was dismissed as a thermodynamic impossibility.
Everything seemed poised against any proposed physical and experimental stability of a structure like graphene. “Thermodynamically impossible”– a not uncommon shutdown to proposed novel physical or chemical concepts– was once used to describe the entire field of proposed two-dimensional crystals functioning separately from a three-dimensional base or crystalline structure. Rudolf Peierls and Lev Davoidovich Landau, both very accomplished physicists respectively known for the Manhattan Project and for developing a mathematical theory of helium superfluidity, rejected the possibility of isolated monolayer to few-layered crystal lattices. Their reasoning was that diverging thermodynamic-based crystal lattice fluctuations would render the material unstable regardless of controlled temperature. This logic is flawed, but not necessarily inaccurate– diamond, for instance, is thermodynamically metastable at room temperature and pressure in that there exists a slow (i.e. slow on the scale of millions of years) but continuous transformation to graphite. However, this logic was used to support an explanation of thermodynamic impossibility that was provided for graphene’s lack of isolation as late as 1979 by Cornell solid-state physicist Nathaniel David Mermin. These physicists’ claims had clear and consistent grounding in experimental data: as thin films become thinner, there exists a trend of a decreasing melting temperature and increasing instability that renders the films into islands at somewhere around ten to twenty atomic layers. This is driven by the thermodynamically-favorable minimization of surface energy.
Everything seemed poised against any proposed physical and experimental stability of a structure like graphene. “Thermodynamically impossible”– a not uncommon shutdown to proposed novel physical or chemical concepts– was once used to describe the entire field of proposed two-dimensional crystals functioning separately from a three-dimensional base or crystalline structure. Rudolf Peierls and Lev Davoidovich Landau, both very accomplished physicists respectively known for the Manhattan Project and for developing a mathematical theory of helium superfluidity, rejected the possibility of isolated monolayer to few-layered crystal lattices. Their reasoning was that diverging thermodynamic-based crystal lattice fluctuations would render the material unstable regardless of controlled temperature. This logic is flawed, but not necessarily inaccurate– diamond, for instance, is thermodynamically metastable at room temperature and pressure in that there exists a slow (i.e. slow on the scale of millions of years) but continuous transformation to graphite. However, this logic was used to support an explanation of thermodynamic impossibility that was provided for graphene’s lack of isolation as late as 1979 by Cornell solid-state physicist Nathaniel David Mermin. These physicists’ claims had clear and consistent grounding in experimental data: as thin films become thinner, there exists a trend of a decreasing melting temperature and increasing instability that renders the films into islands at somewhere around ten to twenty atomic layers. This is driven by the thermodynamically-favorable minimization of surface energy.
ContributorsShulman, Neal Arthur (Author) / Adams, James (Thesis director) / Islam, Rafiqul (Committee member) / Materials Science and Engineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition characterized by a wide range of symptoms and severities, affecting communication, behavior, and social interactions. With the prevalence of ASD rising to affect nearly 1 in 36 children in the United States, understanding and addressing the multifaceted needs of those with ASD is increasingly critical. This review explores the interplay between genetic, environmental, and immune factors in the onset of ASD, focusing on metabolic dysfunctions and the role of the gut-brain axis. Emerging research highlights the significance of abnormal metabolites and gut microbiota imbalances in contributing to the pathophysiology of ASD, suggesting that these factors may influence neurological function and behavior through modulating immune responses.
Recent analyses have uncovered metabolic disturbances in ASD, affecting amino acid metabolism, glutathione metabolism, glycolysis and the TCA cycle, homocysteine metabolism, ketone body synthesis, and lipid metabolism. These disturbances offer insights into how metabolic dysfunctions may contribute to the neurological and behavioral features of ASD. Furthermore, the gut microbiota's role in immune responses and the controversial impact of antibiotic use on gut flora composition is important to the complexity of ASD and the need for a nuanced understanding of treatment effects.
This review delves into the current understanding of metabolic dysfunctions in children with ASD, emphasizing the critical role of gut microbiota and the impact of antibiotic use. Specifically, this review discusses SCFAs, para-cresol, amino acid metabolites, and glutathione and their respective specific treatments. It also explores the potential of vitamin/mineral supplementation as a therapeutic strategy, highlighting significant improvements in metabolic markers and behavioral symptoms associated with ASD. The findings from key studies, including those by Adams et al., suggest that targeted nutritional interventions and careful management of gut health could offer promising avenues for improving the quality of life for individuals with ASD. The review also acknowledges the need for further research to confirm the long-term effects of these interventions and to develop personalized treatment approaches that consider the unique needs in individuals with ASD.
ContributorsNandakumar, Keshav (Author) / Adams, James (Thesis director) / Flynn, Christina (Committee member) / Barrett, The Honors College (Contributor) / Department of Psychology (Contributor)
Created2024-05
Description
Background: Currently, we do not know the direct cause of autism spectrum disorder (ASD). A correlation between the gut microbiome and ASD may play a key role in normalizing ASD symptoms that plague many around the world. Furthermore, microbiota transfer therapy (MTT) may be the next step toward reducing GI symptoms in people impacted with ASD. The Medical Histories of ASD and NT (Neurotypical) adults may help find further information that could help find causes that contribute to the development of ASD.
Objective: To identify key questions in the Medical History Questionnaire and evaluate differences between the ASD and NT participants.
Results: There are 53 ASD participants and 43 NT participants with mean ages of 23.3 and 25.6 respectively. The mean birth weights of each group remain relatively similar (122.3 vs. 117). A greater number of NT participants were delivered vaginally than ASD participants (72.5% vs. 66%). More ASD participants were born before 40 weeks than NT participants (26.4% vs. 7.5%). NT participants, on average, were breastfed almost two times longer than ASD participants (11.2 months vs. 6.4). ASD participants required more time to be toilet trained for both urine and stool output (3.3 years vs. 2.4 years for urine and 4.3 years vs. 2.7 years for stool output). ASD participants have more food allergies with a higher severity and an equal likelihood of seasonal allergies but with a higher severity. ASD participants mainly reported a major regression at an average age of 19.6 months or an abnormal development from early infancy. Maternal and Paternal Histories are more severe in GI problems, ASD, Delayed Speech, Learning Disabilities, Asthma, Eczema, Seasonal and Food Allergies for ASD participants than NT participants. The most significant finding was the ASD participants’ average age of GI symptoms starting was 3.1 compared to 17.9 for NT participants.
Conclusions and Relevance: There are many factors that may contribute to the development of ASD in early childhood. Further research in a larger sample size may demonstrate more significant differences in ASD and NT populations.
ContributorsKazanchi, Alexander (Author) / Adams, James (Thesis director) / Kirby, Jasmine (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor)
Created2024-05